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Scientific Reports Biology Table of Contents e-alert: 02 May 2017

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  02 May 2017   
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Biological Sciences

Erratum: High affinity anchoring of the decoration protein pb10 onto the bacteriophage T5 capsid


Emeline Vernhes, Madalena Renouard, Bernard Gilquin et al.



Corrigendum: Harnessing Nature’s Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins


Reed B. Jacob, Kenan C. Michaels, Cathy J. Anderson et al.



Corrigendum: Arbuscular mycorrhiza enhance the rate of litter decomposition while inhibiting soil microbial community development


Heng Gui, Kevin Hyde, Jianchu Xu et al.



Corrigendum: Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis process


Wenyan Ji, Wujin Sun, Jinmei Feng et al.



WINCS Harmoni: Closed-loop dynamic neurochemical control of therapeutic interventions


Kendall H. Lee, J. Luis Lujan, James K. Trevathan et al.


There has been significant progress in understanding the role of neurotransmitters in normal and pathologic brain function. However, preclinical trials aimed at improving …


Corrigendum: Very rapid long-distance sea crossing by a migratory bird


José A. Alves, Maria P. Dias, Verónica Méndez et al.



Pluronic based β-cyclodextrin polyrotaxanes for treatment of Niemann-Pick Type C disease


Christopher J. Collins, Bradley P. Loren, Md Suhail Alam et al.


Niemann-Pick Type C disease (NPC) is a rare metabolic disorder characterized by disruption of normal cholesterol trafficking within the cells of the body. There are no FDA …


Observability of Boolean multiplex control networks


Yuhu Wu, Jingxue Xu, Xi-Ming Sun et al.


Boolean multiplex (multilevel) networks (BMNs) are currently receiving considerable attention as theoretical arguments for modeling of biological systems and system level …


Prognostic significance of huntingtin interacting protein 1 expression on patients with acute myeloid leukemia


Jinghan Wang, Mengxia Yu, Qi Guo et al.


Huntingtin interacting protein 1 (HIP1) is an endocytic protein which is overexpressed in a variety of human cancers and involved in cancer-causing translocation in leukemia. …


1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function


Mathias Gorski, Peter J. van der Most, Alexander Teumer et al.


HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS …


Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression


Arunava Ghosh, Sabri H. Abdelwahab, Steven L. Reeber et al.


Little cigars (LCs) are regulated differently than cigarettes, allowing them to be potentially targeted at youth/young adults. We exposed human bronchial epithelial cultures …


Corrigendum: Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons


Yousuf O. Ali, Gillian Bradley, Hui-Chen Lu



Manufacturing Differences Affect Human Bone Marrow Stromal Cell Characteristics and Function: Comparison of Production Methods and Products from Multiple Centers


Shutong Liu, Luis F. de Castro, Ping Jin et al.


Human bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) are manufactured using many different methods, but little is known about the …


Guilty repair sustains cooperation, angry retaliation destroys it


Anya Skatova, Alexa Spence, Caroline Leygue et al.


Sustained cooperative social interactions are key to successful outcomes in many real-world contexts (e.g., climate change and energy conservation). We explore the …


Genome-wide identification, characterization, and expression profile of aquaporin gene family in flax (Linum usitatissimum)


S. M. Shivaraj, Rupesh K. Deshmukh, Rhitu Rai et al.


Membrane intrinsic proteins (MIPs) form transmembrane channels and facilitate transport of myriad substrates across the cell membrane in many organisms. Majority of plant MIPs …


Wireless Power Transfer to Millimeter-Sized Gastrointestinal Electronics Validated in a Swine Model


Abubakar Abid, Jonathan M. O’Brien, Taylor Bensel et al.


Electronic devices placed in the gastrointestinal (GI) tract for prolonged periods have the potential to transform clinical evaluation and treatment. One challenge to the …


In situ polymerisation of isoeugenol as a green consolidation method for waterlogged archaeological wood


Emily McHale, Calin C. Steindal, Hartmut Kutzke et al.


Waterlogged archaeological wood is often in need of consolidation prior to drying to prevent shrinkage and cracking of the object. There is a need for new greener materials (than …


Millions of Boreal Shield Lakes can be used to Probe Archaean Ocean Biogeochemistry


S. L. Schiff, J. M. Tsuji, L. Wu et al.


Life originated in Archaean oceans, almost 4 billion years ago, in the absence of oxygen and the presence of high dissolved iron concentrations. Early Earth oxidation is marked …


TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice


Valvanera Fernández-Laso, Cristina Sastre, Nerea Méndez-Barbero et al.


Tumor necrosis factor-like weak inducer of apoptosis (TWEAK/Tnfsf12) is a cytokine implicated in different steps associated with vascular remodeling. However, the role of TWEAK …


The plant cell-wall enzyme AtXTH3 catalyses covalent cross-linking between cellulose and cello-oligosaccharide


Naoki Shinohara, Naoki Sunagawa, Satoru Tamura et al.


Cellulose is an economically important material, but routes of its industrial processing have not been fully explored. The plant cell wall – the major source of cellulose – …


A unifying mathematical framework for experimental TCR-pMHC kinetic constants


Jose Faro, Mario Castro, Carmen Molina-París


Receptor binding and triggering are central in Immunology as T cells activated through their T cell receptors (TCR) by protein antigens orchestrate immune responses. In order to …


Corrigendum: The driving force of prophages and CRISPR-Cas system in the evolution of Cronobacter sakazakii


Haiyan Zeng, Jumei Zhang, Chensi Li et al.



Corrigendum: Characterization of a P1-like bacteriophage carrying CTX-M-27 in Salmonella spp. resistant to third generation cephalosporins isolated from pork in China


Ling Yang, Wan Li, Gui-Ze Jiang et al.



Accelerating recovery from jet lag: prediction from a multi-oscillator model and its experimental confirmation in model animals


Hiroshi Kori, Yoshiaki Yamaguchi, Hitoshi Okamura


The endogenous circadian clock drives oscillations that are completely synchronized with the environmental day–night rhythms with a period of approximately 24 hours. Temporal …


Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina


Steven Hughes, Russell G. Foster, Stuart N. Peirson et al.


Two-pore domain (K2P) potassium channels perform essential roles in neuronal function. These channels produce background leak type potassium currents that act to regulate resting …


Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1+CXCR5−/dim B-helper T cell induction


Toshiki Eri, Kimito Kawahata, Takeyuki Kanzaki et al.


T cell lymphopenia results in peripheral homeostatic expansion to maintain the T cell immune system, which is termed lymphopenia-induced proliferation (LIP). LIP is a potential …


Differences in peripheral sensory input to the olfactory bulb between male and female mice


Marley D. Kass, Lindsey A. Czarnecki, Andrew H. Moberly et al.


Female mammals generally have a superior sense of smell than males, but the biological basis of this difference is unknown. Here, we demonstrate sexually dimorphic neural coding …


Corrigendum: Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia


Francesca Lazzaroni, Luca Del Giacco, Daniele Biasci et al.



Erratum: Loss of miR-542-3p enhances IGFBP-1 expression in decidualizing human endometrial stromal cells


Hideno Tochigi, Takeshi Kajihara, Yosuke Mizuno et al.



Mild MPP+ exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation


Shuichiro Sakamoto, Masatsugu Miyara, Seigo Sanoh et al.


Parkinson’s disease (PD) is a prevalent neurodegenerative disorder, mainly characterised by the progressive loss of dopaminergic neurons. MPP+ has been widely used as a …


Cocaine Cue-Induced Dopamine Release in Recreational Cocaine Users


Sylvia M. L. Cox, Yvonne Yau, Kevin Larcher et al.


It has been proposed that the acquisition of drug seeking is related to the development of conditioned dopamine responses in the ventral striatum. As drug use continues and …


Performance of machine-learning scoring functions in structure-based virtual screening


Maciej Wójcikowski, Pedro J. Ballester, Pawel Siedlecki


Classical scoring functions have reached a plateau in their performance in virtual screening and binding affinity prediction. Recently, machine-learning scoring functions trained …


Role of the virulence plasmid in acid resistance of Shigella flexneri


Chang Niu, Jing Yang, Hongsheng Liu et al.


Virulence plasmid (VP) acquisition was a key step in the evolution of Shigella from a non-pathogenic Escherichia coli ancestor to a pathogenic genus. In addition, the …


Live cell imaging of mitochondria following targeted irradiation in situ reveals rapid and highly localized loss of membrane potential


Dietrich W. M. Walsh, Christian Siebenwirth, Christoph Greubel et al.


The reliance of all cell types on the mitochondrial function for survival makes mitochondria an interesting target when trying to understand their role in the cellular response …


Corrigendum: KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer


Minsuh Kim, Young-Ah Suh, Ju-Hee Oh et al.



Modest and Severe Maternal Iron Deficiency in Pregnancy are Associated with Fetal Anaemia and Organ-Specific Hypoxia in Rats


Andrew G. Woodman, Alison S. Care, Yael Mansour et al.


Prenatal iron-deficiency (ID) is known to alter fetal developmental trajectories, which predisposes the offspring to chronic disease in later life, although the underlying …


Comparative genomics and metabolomics analyses of the adaptation mechanism in Ketogulonicigenium vulgare-Bacillus thuringiensis consortium


Nan Jia, Ming-Zhu Ding, Yang Zou et al.


Adaptive evolution by serial subcultivation of co-cultured Bacillus thuringiensis and Ketogulonicigenium vulgare significantly enhanced the productivity of 2-keto-L-gulonic acid …


A Variation Code Accounts for the Perceived Roughness of Coarsely Textured Surfaces


James M. Goodman, Sliman J. Bensmaia


For decades, the dominant theory of roughness coding in the somatosensory nerves posited that perceived roughness was determined by the spatial pattern of activation in one …


Unravelling the contributions of motor experience and conceptual knowledge in action perception: A training study


S. A. Gerson, M. Meyer, S. Hunnius et al.


Prior knowledge affects how we perceive the world and the sensorimotor system actively guides our perception. An ongoing dispute regards the extent to which prior motor knowledge …


Insecticide-induced leg loss does not eliminate biting and reproduction in Anopheles gambiae mosquitoes


Alison T. Isaacs, Amy Lynd, Martin J. Donnelly


Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. …


Targeting ASIC3 for Relieving Mice Fibromyalgia Pain: Roles of Electroacupuncture, Opioid, and Adenosine


Liang-Ta Yen, Ching-Liang Hsieh, Hsin-Cheng Hsu et al.


Many scientists are seeking better therapies for treating fibromyalgia (FM) pain. We used a mouse model of FM to determine if ASIC3 and its relevant signaling pathway …


Complex multifractal nature in Mycobacterium tuberculosis genome


Saurav Mandal, Tanmoy Roychowdhury, Keilash Chirom et al.


The mutifractal and long range correlation (C(r)) properties of strings, such as nucleotide sequence can be a useful parameter for identification of underlying patterns and …


CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue


Meiyan Dai, Lujin Wu, Peihua Wang et al.


Macrophages in adipose tissue are associated with obesity-induced low-grade inflammation, which contributed to insulin resistance and the related metabolic diseases. Previous …


LPS independent activation of the pro-inflammatory receptor Trem1 by C/EBPε in granulocytes


Hyung C. Suh, Touati Benoukraf, Pavithra Shyamsunder et al.


C/EBPε is a critical transcriptional factor for granulocyte differentiation and function. Individuals with germline mutations of C/EBPε fail to develop normal granulocytes and …


The environmental yeast Cryptococcus liquefaciens produces capsular and secreted polysaccharides with similar pathogenic properties to those of C. neoformans


Glauber R. de S. Araújo, Gustavo J. C. Freitas, Fernanda L. Fonseca et al.


Invasive fungal infections, including cryptococcosis, are a growing threat to immunocompromised patients. Although Cryptococcus neoformans and Cryptococcus gattii are the main …


Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment


Xiaowei Sylvia Chen, Rose H. Reader, Alexander Hoischen et al.


A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language …


Size and shape variations of the bony components of sperm whale cochleae


Joseph G. Schnitzler, Bruno Frédérich, Sven Früchtnicht et al.


Several mass strandings of sperm whales occurred in the North Sea during January and February 2016. Twelve animals were necropsied and sampled around 48 h after their discovery …


Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis


S. Lugert, T. Kremer, R. Jagasia et al.


Adult hippocampal neurogenesis is a remarkable form of brain plasticity through which new neurons are generated throughout life. Despite its important roles in cognition and …


Quantitative diagnosis of breast tumors by morphometric classification of microenvironmental myoepithelial cells using a machine learning approach


Yoichiro Yamamoto, Akira Saito, Ayako Tateishi et al.


Machine learning systems have recently received increased attention for their broad applications in several fields. In this study, we show for the first time that histological …


Corrigendum: Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity


Yukti Choudhury, Yi Chin Toh, Jiangwa Xing et al.



Klf5 Mediates Odontoblastic Differentiation through Regulating Dentin-Specific Extracellular Matrix Gene Expression during Mouse Tooth Development


Zhuo Chen, Qi Zhang, Han Wang et al.


Klf5, a member of the Krüppel-like transcription factor family, has essential roles during embryonic development, cell proliferation, differentiation, migration and apoptosis. …


Identifying N6-methyladenosine sites using multi-interval nucleotide pair position specificity and support vector machine


Pengwei Xing, Ran Su, Fei Guo et al.


N6-methyladenosine (m6A) refers to methylation of the adenosine nucleotide acid at the nitrogen-6 position. It plays an important role in a series of biological processes, such …


Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense


Wanyan Deng, Quanxin Long, Jie Zeng et al.


The success of Mycobacterium tuberculosis (M. tuberculosis) as a pathogen is largely contributes to its ability to manipulate the host immune responses. The genome of M. …

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