TABLE OF CONTENTS
| | | | Volume 116, Issue 8 (973-1118) Published online 11 April 2017
| | In this issue Review Clinical Studies Translational Therapeutics Molecular Diagnostics Epidemiology Letters to the Editor
Also new today Advance online publication Digital Edition
| | | | | | Advertisement | | BACR 2017 Conferences The BACR hosts a number of specialist cancer meetings to bring together the latest thinking in cancer research. Having links with organisations such as EACR,NCRI and RSM boosts opportunities for networking and establishing collaborations with leaders in cancer research. Interested in attending/or presenting then visit www.bacr.org.uk/events | | | | | | | | Review | Top | | A unified model of the hierarchical and stochastic theories of gastric cancerYanjing Song, Yao Wang, Chuan Tong, Hongqing Xi, Xudong Zhao, Yi Wang and Lin Chen Br J Cancer 2017 116: 973-989; advance online publication, March 16, 2017; 10.1038/bjc.2017.54 Abstract | Full Text | | Clinical Studies | Top | | MEK inhibition appears to improve symptom control in primary NRAS-driven CNS melanoma in childrenVeronica A Kinsler, Patricia O'Hare, Thomas Jacques, Darren Hargrave and Olga Slater Br J Cancer 2017 116: 990-993; advance online publication, March 2, 2017; 10.1038/bjc.2017.49 Abstract | Full Text | | | | Predicting serious complications in patients with cancer and pulmonary embolism using decision tree modelling: the EPIPHANY IndexA Carmona-Bayonas, P Jiménez-Fonseca, C Font, F Fenoy, R Otero, C Beato, J M Plasencia, M Biosca, M Sánchez, M Benegas, D Calvo-Temprano, D Varona, L Faez, I de la Haba, M Antonio, O Madridano, M P Solis, A Ramchandani, E Castañón, P J Marchena, M Martín, F Ayala de la Peña and V Vicente on behalf of the Asociación de Investigación de la Enfermedad Tromboembólica de la Región de Murcia (the Region of Murcia’s Association of Thromboembolic Disease Research) Br J Cancer 2017 116: 994-1001; advance online publication, March 7, 2017; 10.1038/bjc.2017.48 Abstract | Full Text | | | | Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancerHui-Ming Lin, Kate L Mahon, Calan Spielman, Howard Gurney, Girish Mallesara, Martin R Stockler, Patricia Bastick, Karen Briscoe, Gavin Marx, Alexander Swarbrick and Lisa G Horvath Br J Cancer 2017 116: 1002-1011; advance online publication, March 9, 2017; 10.1038/bjc.2017.50 Abstract | Full Text | | | | Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification systemJeong Mo Bae, Jung Ho Kim, Yoonjin Kwak, Dae-Won Lee, Yongjun Cha, Xianyu Wen, Tae Hun Lee, Nam-Yun Cho, Seung-Yong Jeong, Kyu Joo Park, Sae Won Han, Hye Seung Lee, Tae-You Kim and Gyeong Hoon Kang Br J Cancer 2017 116: 1012-1020; advance online publication, March 9, 2017; 10.1038/bjc.2017.52 Abstract | Full Text | | | | BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancerMichael J Pishvaian, Andrew V Biankin, Peter Bailey, David K Chang, Daniel Laheru, Christopher L Wolfgang and Jonathan R Brody Br J Cancer 2017 116: 1021-1026; advance online publication, March 14, 2017; 10.1038/bjc.2017.40 Abstract | Full Text | | Translational Therapeutics | Top | | Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1Li Xu, Yuanrun Zhu, Jinjin Shao, Min Chen, Hao Yan, Guanqun Li, Yi Zhu, Zhifei Xu, Bo Yang, Peihua Luo and Qiaojun He Br J Cancer 2017 116: 1027-1036; advance online publication, March 7, 2017; 10.1038/bjc.2017.55 Abstract | Full Text | | | | Carcinoembryonic antigen and cytokeratin-19 fragments for assessment of therapy response in non-small cell lung cancer: a systematic review and meta-analysisStefan Holdenrieder, Birgit Wehnl, Karina Hettwer, Kirsten Simon, Steffen Uhlig and Farshid Dayyani Br J Cancer 2017 116: 1037-1045; advance online publication, March 9, 2017; 10.1038/bjc.2017.45 Abstract | Full Text | | | | Comprehensive molecular exploration identified promoter DNA methylation of the CRBP1 gene as a determinant of radiation sensitivity in rectal cancerK Yokoi, K Yamashita, S Ishii, T Tanaka, N Nishizawa, A Tsutsui, H Miura, H Katoh, T Yamanashi, M Naito, T Sato, T Nakamura and M Watanabe Br J Cancer 2017 116: 1046-1056; advance online publication, March 14, 2017; 10.1038/bjc.2017.65 Abstract | Full Text | | | | Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinomaYae-eun Suh, Katherine Lawler, Rhonda Henley-Smith, Lucy Pike, Russell Leek, Sally Barrington, Edward W Odell, Tony Ng, Francesco Pezzella, Teresa Guerrero-Urbano and Mahvash Tavassoli Br J Cancer 2017 116: 1057-1064; advance online publication, March 21, 2017; 10.1038/bjc.2017.66 Abstract | Full Text | | Molecular Diagnostics | Top | | VEPH1 expression decreases vascularisation in ovarian cancer xenografts and inhibits VEGFA and IL8 expression through inhibition of AKT activationPremalatha Shathasivam, Alexandra Kollara, Thomasina Spybey, Soyeon Park, Blaise Clarke, Maurice J Ringuette and Theodore J Brown Br J Cancer 2017 116: 1065-1076; advance online publication, March 16, 2017; 10.1038/bjc.2017.51 Abstract | Full Text | | | | Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancerTakashi Sakaguchi, Hirofumi Yoshino, Masaya Yonemori, Kazutaka Miyamoto, Satoshi Sugita, Ryosuke Matsushita, Toshihiko Itesako, Shuichi Tatarano, Masayuki Nakagawa and Hideki Enokida Br J Cancer 2017 116: 1077-1087; advance online publication, March 21, 2017; 10.1038/bjc.2017.43 Abstract | Full Text | | | | Examining the common aetiology of serous ovarian cancers and basal-like breast cancers using double primariesColin B Begg, Megan S Rice, Emily C Zabor and Shelley S Tworoger Br J Cancer 2017 116: 1088-1091; advance online publication, March 23, 2017; 10.1038/bjc.2017.73 Abstract | Full Text | | Epidemiology | Top | | The impact of vitamin D pathway genetic variation and circulating 25-hydroxyvitamin D on cancer outcome: systematic review and meta-analysisP G Vaughan-Shaw, F O'Sullivan, S M Farrington, E Theodoratou, H Campbell, M G Dunlop and L Zgaga Br J Cancer 2017 116: 1092-1110; advance online publication, March 16, 2017; 10.1038/bjc.2017.44 Abstract | Full Text | | | | The effect of ovarian cancer screening on sexual activity and functioning: results from the UK collaborative trial of ovarian cancer screening RCTLesley Fallowfield, Ivonne Solis-Trapala, Usha Menon, Carolyn Langridge, Shirley May, Ian Jacobs and Valerie Jenkins for and on behalf of the UKCTOCS trialists Br J Cancer 2017 116: 1111-1117; advance online publication, March 21, 2017; 10.1038/bjc.2017.72 Abstract | Full Text | | Letters to the Editor | Top | | Comment on ‘Statin use and all-cancer survival: prospective results from the Women’s Health Initiative’Uffe Ravnskov Br J Cancer 2017 116: e9; advance online publication, March 9, 2017; 10.1038/bjc.2017.41 Full Text | | | | Comment on ‘Nomogram to predict pathologic complete response in HER2-positive breast cancer treated with neoadjuvant systemic therapy’Kadri Altundag Br J Cancer 2017 116: e10; advance online publication, March 14, 2017; 10.1038/bjc.2017.60 Full Text | | | | Reply to ‘Comment on ‘Nomogram to predict pathologic complete response in HER2-positive breast cancer treated with neoadjuvant systemic therapy’’Takeo Fujii and Naoto T Ueno Br J Cancer 2017 116: e11; advance online publication, March 14, 2017; 10.1038/bjc.2017.61 Full Text | | | | Comment on ‘The burden of occupationally-related cutaneous malignant melanoma in Britain due to solar radiation’William B Grant Br J Cancer 2017 116: e12; advance online publication, March 16, 2017; 10.1038/bjc.2017.63 Full Text | | | | Reply to ‘Comment on ‘The burden of occupationally-related cutaneous malignant melanoma in Britain due to solar radiation’’ – outdoor occupation may not be linked to increased risk of melanoma in BritainLesley Rushton and Sally J Hutchings Br J Cancer 2017 116: e13; advance online publication, March 16, 2017; 10.1038/bjc.2017.64 Full Text | | | | Comment on ‘Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy’Keisuke Imafuku, Koji Yoshino, Kei Yamaguchi, Satoshi Tsuboi, Kuniaki Ohara and Hiroo Hata Br J Cancer 2017 116: e14; advance online publication, March 21, 2017; 10.1038/bjc.2017.58 Full Text | | | | Reply to ‘Comment on ‘Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy’’Samantha Bowyer, Prashanth Prithviraj, Paul Lorigan, James Larkin, Grant McArthur, Victoria Atkinson, Michael Millward, Muoi Khou, Stefan Diem, Sangeetha Ramanujam, Ben Kong, Elizabeth Liniker, Alexander Guminski, Phillip Parente, Miles C Andrews, Sagun Parakh, Jonathan Cebon, Georgina V Long, Matteo S Carlino and Oliver Klein Br J Cancer 2017 116: e15; advance online publication, March 21, 2017; 10.1038/bjc.2017.59 Full Text | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to British Journal of Cancer. 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