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TABLE OF CONTENTS
| | | | Volume 116, Issue 5 (553-696) Published online 28 February 2017
| | In this issue Review Clinical Studies Translational Therapeutics Molecular Diagnostics Genetics & Genomics Epidemiology
Also new today Advance online publication Digital Edition
| | | | Review | Top | | Tissue-based next generation sequencing: application in a universal healthcare systemSeán O Hynes, Brendan Pang, Jacqueline A James, Perry Maxwell and Manuel Salto-Tellez Br J Cancer 2017 116: 553-560; advance online publication, January 19, 2017; 10.1038/bjc.2016.452 Abstract | Full Text | | Clinical Studies | Top | | Efficacy of fluoropyrimidine-based chemotherapy in patients with advanced biliary tract cancer after failure of gemcitabine plus cisplatin: retrospective analysis of 321 patientsBum Jun Kim, Changhoon Yoo, Kyu-pyo Kim, Jaewon Hyung, Seong Joon Park, Baek-Yeol Ryoo and Heung-Moon Chang Br J Cancer 2017 116: 561-567; advance online publication, January 12, 2017; 10.1038/bjc.2016.446 Abstract | Full Text | | | | A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutationsJ J Yang, Q Zhou, H H Yan, X C Zhang, H J Chen, H Y Tu, Z Wang, C R Xu, J Su, B C Wang, B Y Jiang, X Y Bai, W Z Zhong, X N Yang and Y L Wu Br J Cancer 2017 116: 568-574; advance online publication, January 19, 2017; 10.1038/bjc.2016.456 Abstract | Full Text | | | | A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitorJohanna C Bendell, Milind Javle, Tanios S Bekaii-Saab, Richard S Finn, Zev A Wainberg, Daniel A Laheru, Colin D Weekes, Benjamin R Tan, Gazala N Khan, Mark M Zalupski, Jeffrey R Infante, Suzanne Jones, Kyriakos P Papadopoulos, Anthony W Tolcher, Renae E Chavira, Janna L Christy-Bittel, Emma Barrett and Amita Patnaik Br J Cancer 2017 116: 575-583; advance online publication, February 2, 2017; 10.1038/bjc.2017.10 Abstract | Full Text | | | | Comparison of two protocols for the management of asymptomatic postmenopausal women with adnexal tumours – a randomised controlled trial of RMI/RCOG vs Simple RulesNatalie Nunes, Gareth Ambler, Xulin Foo, Joel Naftalin, Grigoris Derdelis, Martin Widschwendter and Davor Jurkovic Br J Cancer 2017 116: 584-591; advance online publication, February 2, 2017; 10.1038/bjc.2017.17 Abstract | Full Text | | Translational Therapeutics | Top | | Aurora B expression modulates paclitaxel response in non-small cell lung cancerAhmed SK Al-Khafaji, Michael PA Davies, Janet M Risk, Michael W Marcus, Maria Koffa, John R Gosney, Richard J Shaw, John K Field and Triantafillos Liloglou Br J Cancer 2017 116: 592-599; advance online publication, January 17, 2017; 10.1038/bjc.2016.453 Abstract | Full Text | | | | A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix depositionL M Schiffmann, M Brunold, M Liwschitz, V Goede, S Loges, M Wroblewski, A Quaas, H Alakus, D Stippel, C J Bruns, M Hallek, H Kashkar, U T Hacker and O Coutelle Br J Cancer 2017 116: 600-608; advance online publication, January 31, 2017; 10.1038/bjc.2017.13 Abstract | Full Text | | | | Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCKGirijesh Kumar Patel, Mohammad Aslam Khan, Arun Bhardwaj, Sanjeev K Srivastava, Haseeb Zubair, Mary C Patton, Seema Singh, Moh'd Khushman and Ajay P Singh Br J Cancer 2017 116: 609-619; advance online publication, February 2, 2017; 10.1038/bjc.2017.18 Abstract | Full Text | | | | Neratinib resistance and cross-resistance to other HER2-targeted drugs due to increased activity of metabolism enzyme cytochrome P4503A4Susan Breslin, Michelle C Lowry and Lorraine O'Driscoll Br J Cancer 2017 116: 620-625; advance online publication, February 2, 2017; 10.1038/bjc.2016.445 Abstract | Full Text | | Molecular Diagnostics | Top | | Circular RNA 0000096 affects cell growth and migration in gastric cancerPeifei Li, Huilin Chen, Shengcan Chen, Xiaoyan Mo, Tianwen Li, Bingxiu Xiao, Rui Yu and Junming Guo Br J Cancer 2017 116: 626-633; advance online publication, January 12, 2017; 10.1038/bjc.2016.451 Abstract | Full Text | | | | MicroRNA promoter methylation: a new tool for accurate detection of urothelial carcinomaNuno André Padrão, Sara Monteiro-Reis, Jorge Torres-Ferreira, Luís Antunes, Luís Leça, Diana Montezuma, João Ramalho-Carvalho, Paula C Dias, Paula Monteiro, Jorge Oliveira, Rui Henrique and Carmen Jerónimo Br J Cancer 2017 116: 634-639; advance online publication, January 12, 2017; 10.1038/bjc.2016.454 Abstract | Full Text | | | | Tenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groupsElias Sundquist, Joonas H Kauppila, Johanna Veijola, Rayan Mroueh, Petri Lehenkari, Saara Laitinen, Juha Risteli, Ylermi Soini, Veli-Matti Kosma, Iris Sawazaki-Calone, Carolina Carneiro Soares Macedo, Risto Bloigu, Ricardo D Coletta and Tuula Salo Br J Cancer 2017 116: 640-648; advance online publication, January 17, 2017; 10.1038/bjc.2016.455 Abstract | Full Text | | | | The predictive and prognostic value of tumour necrosis in muscle invasive bladder cancer patients receiving radiotherapy with or without chemotherapy in the BC2001 trial (CRUK/01/004)Ananya Choudhury, Catharine M West, Nuria Porta, Emma Hall, Helen Denley, Carey Hendron, Rebecca Lewis, Syed A Hussain, Robert Huddart and Nicholas James on behalf of the BC2001 investigators Br J Cancer 2017 116: 649-657; advance online publication, January 26, 2017; 10.1038/bjc.2017.2 Abstract | Full Text | | Genetics & Genomics | Top | | Epigenomic landscape of 5-hydroxymethylcytosine reveals its transcriptional regulation of lncRNAs in colorectal cancerHanyang Hu, Maoguo Shu, Lin He, Xueyuan Yu, Xiangyu Liu, Yalin Lu, Yinghong Chen, Xiaoping Miao and Xiaohua Chen Br J Cancer 2017 116: 658-668; advance online publication, January 31, 2017; 10.1038/bjc.2016.457 Abstract | Full Text | | | | The spectrum of EWSR1-rearranged neoplasms at a tertiary sarcoma centre; assessing 772 tumour specimens and the value of current ancillary molecular diagnostic modalitiesJonathan Noujaim, Robin L Jones, John Swansbury, David Gonzalez, Charlotte Benson, Ian Judson, Cyril Fisher and Khin Thway Br J Cancer 2017 116: 669-678; advance online publication, January 31, 2017; 10.1038/bjc.2017.4 Abstract | Full Text | | Epidemiology | Top | | Composite protective lifestyle factors and risk of developing gastric adenocarcinoma: the Singapore Chinese Health StudyZhensheng Wang, Woon-Puay Koh, Aizhen Jin, Renwei Wang and Jian-Min Yuan Br J Cancer 2017 116: 679-687; advance online publication, January 26, 2017; 10.1038/bjc.2017.7 Abstract | Full Text | | | | Circulating copper and zinc levels and risk of hepatobiliary cancers in EuropeansMagdalena Stepien, David J Hughes, Sandra Hybsier, Christina Bamia, Anne Tjønneland, Kim Overvad, Aurélie Affret, Mathilde His, Marie-Christine Boutron-Ruault, Verena Katzke, Tilman Kühn, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Phlippos Orfanos, Domenico Palli, Sabina Sieri, Rosario Tumino, Fulvio Ricceri, Salvatore Panico, H B(as) Bueno-de-Mesquita, Petra H Peeters, Elisabete Weiderpass, Cristina Lasheras, Catalina Bonet Bonet, Elena Molina-Portillo, Miren Dorronsoro, José María Huerta, Aurelio Barricarte, Bodil Ohlsson, Klas Sjöberg, Mårten Werner, Dmitry Shungin, Nick Wareham, Kay-Tee Khaw, Ruth C Travis, Heinz Freisling, Amanda J Cross, Lutz Schomburg and Mazda Jenab Br J Cancer 2017 116: 688-696; advance online publication, February 2, 2017; 10.1038/bjc.2017.1 Abstract | Full Text | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to British Journal of Cancer. 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