Tuesday, February 14, 2017

Immunology and Cell Biology - Table of Contents alert Volume 95 Issue 2

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Immunology and Cell Biology

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Pixels to data: Quantitative cell biology using high-content imaging and analysis.

Date: Tuesday 28 February 2017

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The February 2017 issue contains a Special Feature on Necroptotic death signalling: evolution, mechanisms and disease relevance. In recent years, research into a genetically encoded cell death program termed necroptosis has accelerated into vogue. Many laboratories are now racing to answer key questions such as: How does it occur? When does it occur? What does it do? What is it good (or not so good) for? Answers to these will ultimately guide efforts aimed at manipulating this new pathway for therapeutic benefit. In the six articles in this ICB Special Feature, the current state of play in necroptotic cell death research is dissected in considerable detail. The articles provide timely updates on what we have learnt so far and, importantly, where we might be going. Immunology & Cell Biology thanks the coordinator of this Special Feature - James Vince - for his planning and input.

Please see articles marked


Volume 95, Issue 2 (February 2017)

In this issue
News and Commentaries
Outstanding Observation
Original Articles
Short Communication
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News and Commentaries


Epithelial extracellular ATP: an initiator of immunity to parasitic infections

Sean Nelson, Hiroshi Kiyono and Yosuke Kurashima

Immunol Cell Biol 2017 95: 117-118; advance online publication, November 22, 2016; 10.1038/icb.2016.106

Full Text

See also: Original Article by Huang et al.

Lymphocytic division clocked up by Myc

Amir Erez and Grégoire Altan-Bonnet

Immunol Cell Biol 2017 95: 119-120; advance online publication, December 20, 2016; 10.1038/icb.2016.115

Full Text

Outstanding Observation


Protein tyrosine phosphatase PTPN22 has dual roles in promoting pathogen versus homeostatic-driven CD8 T-cell responses

Tatiana Jofra, Roberta Di Fonte, Tarun Edgar Hutchinson, Farhad Dastmalchi, Giuseppe Galvani, Manuela Battaglia, Shahram Salek-Ardakani and Georgia Fousteri

Immunol Cell Biol 2017 95: 121-128; advance online publication, October 11, 2016; 10.1038/icb.2016.92

Abstract | Full Text



Necroptotic death signaling: evolution, mechanisms and disease relevance  

James E Vince

Immunol Cell Biol 2017 95: 129-130; 10.1038/icb.2016.119

Full Text | PDF



Controlled detonation: evolution of necroptosis in pathogen defense  

Michelle Brault and Andrew Oberst

Immunol Cell Biol 2017 95: 131-136; advance online publication, December 20, 2016; 10.1038/icb.2016.117

Abstract | Full Text

Relevance of necroptosis in cancer  

Najoua Lalaoui and Gabriela Brumatti

Immunol Cell Biol 2017 95: 137-145; advance online publication, January 17, 2017; 10.1038/icb.2016.120

Abstract | Full Text

A motive for killing: effector functions of regulated lytic cell death  

Meghan Bliss-Moreau, Alyce A Chen, Akshay A D'Cruz and Ben A Croker

Immunol Cell Biol 2017 95: 146-151; advance online publication, November 29, 2016; 10.1038/icb.2016.113

Abstract | Full Text

Insane in the membrane: a structural perspective of MLKL function in necroptosis  

Emma J Petrie, Joanne M Hildebrand and James M Murphy

Immunol Cell Biol 2017 95: 152-159; advance online publication, January 17, 2017; 10.1038/icb.2016.125

Abstract | Full Text

Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins  

Lazaros Vasilikos, Lisanne M Spilgies, Janin Knop and Wendy Wei-Lynn Wong

Immunol Cell Biol 2017 95: 160-165; advance online publication, January 3, 2017; 10.1038/icb.2016.118

Abstract | Full Text

Mechanisms of RIPK3-induced inflammation  

Inbar Shlomovitz, Sefi Zargrian and Motti Gerlic

Immunol Cell Biol 2017 95: 166-172; advance online publication, January 3, 2017; 10.1038/icb.2016.124

Abstract | Full Text



Tissue-resident macrophages — how to humanize our knowledge

Andreas Schlitzer and Joachim L Schultze

Immunol Cell Biol 2017 95: 173-177; advance online publication, October 18, 2016; 10.1038/icb.2016.82

Abstract | Full Text

Original Articles


P2X7 receptor-dependent tuning of gut epithelial responses to infection OPEN

Szu-Wei Huang, Catherine Walker, Joanne Pennock, Kathryn Else, Werner Muller, Michael JD Daniels, Carolina Pellegrini, David Brough, Gloria Lopez-Castejon and Sheena M Cruickshank

Immunol Cell Biol 2017 95: 178-188; advance online publication, September 20, 2016; 10.1038/icb.2016.75

Abstract | Full Text

See also: News and Commentary by Nelson et al.

Anti-CD45RB and donor-specific spleen cells transfusion inhibition allograft skin rejection mediated by memory T cells

You-Qiang Jian, Jian Ye, Hui Qi, Chun-Yan Deng, Shao-Ping Deng and Fu-Rong Li

Immunol Cell Biol 2017 95: 189-197; advance online publication, September 12, 2016; 10.1038/icb.2016.88

Abstract | Full Text

Macrophage polarization and MRSA infection in burned mice

Tomoki Nishiguchi, Ichiaki Ito, Jong O Lee, Sumihiro Suzuki, Fujio Suzuki and Makiko Kobayashi

Immunol Cell Biol 2017 95: 198-206; advance online publication, September 6, 2016; 10.1038/icb.2016.84

Abstract | Full Text

Impaired activation of ALS monocytes by exosomes

Lisa Zondler, Marisa S Feiler, Axel Freischmidt, Wolfgang P Ruf, Albert C Ludolph, Karin M Danzer and Jochen H Weishaupt

Immunol Cell Biol 2017 95: 207-214; advance online publication, September 12, 2016; 10.1038/icb.2016.89

Abstract | Full Text

Short Communication


Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and function

Janin Chandra, Paula T Y Kuo, Anne M Hahn, Gabrielle T Belz and Ian H Frazer

Immunol Cell Biol 2017 95: 215-223; advance online publication, November 29, 2016; 10.1038/icb.2016.83

Abstract | Full Text

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