 | An experimental method based on the perturbation of isogenic cell lines followed by selection, transformation and deep sequencing is presented to study the onset and the consequences of chromothripsis, a massive DNA rearrangement process observed in cancer genomes. Balca R Mardin, Alexandros P Drainas, Sebastian M Waszak, Joachim Weischenfeldt, Mayumi Isokane, Adrian M Stütz, Benjamin Raeder, Theocharis Efthymiopoulos, Christopher Buccitelli, Maia Segura‐Wang, Paul Northcott, Stefan M Pfister, Peter Lichter, Jan Ellenberg, and Jan O Korbel |
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