The EMBO Journal Table of Contents for 1 October 2015; Vol. 34, No. 19

1 October 2015 | Volume 34, Number 19 Submit Table of Contents News & Views Correspondence Review Articles Corrigendum Volume 34, Number 19 News & Views α‐Synuclein oligomers pump it up! Oligomeric forms of the Parkinson's disease‐causing protein α‐synuclein sequester the neuronal sodium–potassium pump to perturb ion currents, ultimately leading to Ca2+ excitotoxicity. Philipp J Kahle, Naoto Sugeno, and Angelos Skodras Published online 15.09.2015 The tumor suppressor FBW7 controls ciliary length New work reveals ubiquitin‐dependent degradation of NDE1 as a mechanism linking cell cycle stage to ciliogenesis. Anna S Nikonova and Erica A Golemis Published online 12.08.2015 The different autophagic roads by which phagosomes travel to lysosomes The engulfment of phagosomes by autophagosomes is required for delivery to lysosomes and for MHC restricted antigen presentation. Christian Münz Published online 02.09.2015 Correspondence cIAP2 supports viability of mice lacking cIAP1 and XIAP Kristen N Heard, Mathieu JM Bertrand, and Philip A Barker Published online 30.09.2015 Response to Heard et al Maryline Moulin, Anne K Voss, Tim Thomas, Wendy Wei‐Lynn Wong, Wendy D Cook, Frank Koentgen, James Vince, John Silke, and David L Vaux Published online 30.09.2015 Review ESCRTs are everywhere ESCRT complexes are required for membrane remodeling and scission; this review highlights their role in cellular processes ranging from exosome generation to the reformation of the nuclear envelope. James H Hurley Published online 25.08.2015 Articles α‐synuclein assemblies sequester neuronal α3‐Na+/K+‐ATPase and impair Na+ gradient Oligomeric and fibrillar forms of the Parkinson's disease linked protein α‐synuclein interact with the α3‐NKA sodium potassium pump to perturb ion currents in neurons. Amulya Nidhi Shrivastava, Virginie Redeker, Nicolas Fritz, Laura Pieri, Leandro G Almeida, Maria Spolidoro, Thomas Liebmann, Luc Bousset, Marianne Renner, Clément Léna, Anita Aperia, Ronald Melki, and Antoine Triller Published online 31.08.2015 Cell cycle‐dependent ubiquitylation and destruction of NDE1 by CDK5‐FBW7 regulates ciliary length Quiescence‐specific kinase CDK5 initiates NDE1 degradation to couple cell cycle state to length control of primary cilia. Dipak Maskey, Matthew Caleb Marlin, Seokho Kim, Sehyun Kim, E‐Ching Ong, Guangpu Li, and Leonidas Tsiokas Published online 23.07.2015 KIM‐1‐/TIM‐1‐mediated phagocytosis links ATG5‐/ULK1‐dependent clearance of apoptotic cells to antigen presentation Phosphatidylserine receptor KIM‐1/TIM‐1‐mediated phagocytosis and autophagic processing of apoptotic cells promote antigen presentation in epithelial cells to modulate inflammation. Craig R Brooks, Melissa Y Yeung, Yang S Brooks, Hui Chen, Takaharu Ichimura, Joel M Henderson, and Joseph V Bonventre Published online 17.08.2015 Polynucleotide kinase–phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability Polynucleotide kinase‐phosphatase is essential for normal brain development by preventing the accumulation of endogenous DNA single‐ and double‐strand breaks, which otherwise results in widespread cell death during neurogenesis. Mikio Shimada, Lavinia C Dumitrache, Helen R Russell, and Peter J McKinnon Published online 19.08.2015 Corrigendum The inner membrane histidine kinase EnvZ senses osmolality via helix‐coil transitions in the cytoplasm Loo Chien Wang, Leslie K Morgan, Pahan Godakumbura, Linda J Kenney, and Ganesh S Anand Published online 30.09.2015   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2015 by the European Molecular Biology Organisation.