TABLE OF CONTENTS
|  |  |  | Volume 28, Issue 10 (October 2014) |  | In this issue Review Concise Review Original Articles Letters to the Editor
Also new    AOP | |  |  |  | | Advertisement |  | Nature Communications soon to be fully open access From 20th October Nature Communications, will become fully open access for all new submissions. If an author has a manuscript they wish to submit to the journal via the subscription route, they must submit before 20th October. After this date all new submissions, if accepted, will be published open access and an article processing charge (APC) will apply. For any questions on the switch, open access or advice on policies and funding, visit our website, read the press release or contact our dedicated support team at openaccess@nature.com. |  | | |  |  | Review | Top |  | Mesenchymal stromal cells in the antimicrobial host response of hematopoietic stem cell recipients with graft-versus-host disease—friends or foes?A Balan, G Lucchini, S Schmidt, A Schneider, L Tramsen, S Kuçi, R Meisel, P Bader and T Lehrnbecher Leukemia 2014 28: 1941-1948; advance online publication, April 3, 2014; 10.1038/leu.2014.127 Abstract | Full Text |  | Concise Review | Top |  | Should persons with acute myeloid leukemia have a transplant in first remission?R P Gale, P H Wiernik and H M Lazarus Leukemia 2014 28: 1949-1952; advance online publication, April 14, 2014; 10.1038/leu.2014.129 Abstract | Full Text |  | Original Articles | Top |  | MOLECULAR TARGETS FOR THERAPY | The prognostic relevance of flt3 and npm1 mutations on older patients treated intensively or non-intensively: a study of 1312 patients in the UK NCRI AML16 trialM Lazenby, A F Gilkes, C Marrin, A Evans, R K Hills and A K Burnett Leukemia 2014 28: 1953-1959; advance online publication, February 27, 2014; 10.1038/leu.2014.90 Abstract | Full Text |  |  |  | THERAPY | Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activityK P Callahan, M Minhajuddin, C Corbett, E D Lagadinou, R M Rossi, V Grose, M M Balys, L Pan, S Jacob, A Frontier, M R Grever, D M Lucas, A D Kinghorn, J L Liesveld, M W Becker and C T Jordan Leukemia 2014 28: 1960-1968; advance online publication, February 28, 2014; 10.1038/leu.2014.93 Abstract | Full Text |  |  |  | ACUTE LEUKEMIAS | Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human acute myeloid leukemiaR B Walter, G S Laszlo, J M Lionberger, J A Pollard, K H Harrington, C J Gudgeon, M Othus, S Rafii, S Meshinchi, F R Appelbaum and I D Bernstein Leukemia 2014 28: 1969-1977; advance online publication, March 18, 2014; 10.1038/leu.2014.107 Abstract | Full Text |  |  |  | Functional integration of acute myeloid leukemia into the vascular nicheC R Cogle, D C Goldman, G J Madlambayan, R P Leon, A Al Masri, H A Clark, S A Asbaghi, J W Tyner, J Dunlap, G Fan, T Kovacsovics, Q Liu, A Meacham, K L Hamlin, R A Hromas, E W Scott and W H Fleming Leukemia 2014 28: 1978-1987; advance online publication, March 18, 2014; 10.1038/leu.2014.109 Abstract | Full Text |  |  |  | CHRONIC MYELOPROLIFERATIVE NEOPLASIAS | Velocity of early BCR-ABL transcript elimination as an optimized predictor of outcome in chronic myeloid leukemia (CML) patients in chronic phase on treatment with imatinibB Hanfstein, V Shlyakhto, M Lauseker, R Hehlmann, S Saussele, C Dietz, P Erben, A Fabarius, U Proetel, S Schnittger, S W Krause, J Schubert, H Einsele, M Hänel, J Dengler, C Falge, L Kanz, A Neubauer, M Kneba, F Stegelmann, M Pfreundschuh, C F Waller, K Spiekermann, G M Baerlocher, M Pfirrmann, J Hasford, W-K Hofmann, A Hochhaus, M C Müller and for the SAKK and the German CML Study Group Leukemia 2014 28: 1988-1992; advance online publication, May 6, 2014; 10.1038/leu.2014.153 Abstract | Full Text |  |  |  | CHRONIC LYMPHOCYTIC LEUKEMIA | Targeting the proliferative and chemoresistant compartment in chronic lymphocytic leukemia by inhibiting survivin proteinN Purroy, P Abrisqueta, J Carabia, C Carpio, E Calpe, C Palacio, J Castellví, M Crespo and F Bosch Leukemia 2014 28: 1993-2004; advance online publication, March 12, 2014; 10.1038/leu.2014.96 Abstract | Full Text |  |  |  | Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemiaD Saulep-Easton, F B Vincent, M Le Page, A Wei, S B Ting, C M Croce, C Tam and F Mackay Leukemia 2014 28: 2005-2015; advance online publication, March 18, 2014; 10.1038/leu.2014.105 Abstract | Full Text |  |  |  | IMMUNOLOGY | Comparative analysis of FoxP3+ regulatory T cells in the target tissues and blood in chronic graft versus host diseaseM M Imanguli, E W Cowen, J Rose, S Dhamala, W Swaim, S Lafond, B Yagi, R E Gress, S Z Pavletic and F T Hakim Leukemia 2014 28: 2016-2027; advance online publication, February 28, 2014; 10.1038/leu.2014.92 Abstract | Full Text |  |  |  | ONCOGENES, FUSION GENES AND TUMOR SUPPRESSOR GENES | A ‘telomere-associated secretory phenotype’ cooperates with BCR-ABL to drive malignant proliferation of leukemic cellsM Braig, N Pällmann, M Preukschas, D Steinemann, W Hofmann, A Gompf, T Streichert, T Braunschweig, M Copland, K L Rudolph, C Bokemeyer, S Koschmieder, A Schuppert, S Balabanov and T H Brümmendorf Leukemia 2014 28: 2028-2039; advance online publication, March 7, 2014; 10.1038/leu.2014.95 Abstract | Full Text |  |  |  | Structural basis of Ets1 activation by Runx1T Shrivastava, K Mino, N D Babayeva, O I Baranovskaya, A Rizzino and T H Tahirov Leukemia 2014 28: 2040-2048; advance online publication, March 20, 2014; 10.1038/leu.2014.111 Abstract | Full Text |  |  |  | LYMPHOMA | Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphomaA Moros, V Rodríguez, I Saborit-Villarroya, A Montraveta, P Balsas, P Sandy, A Martínez, A Wiestner, E Normant, E Campo, P Pérez-Galán, D Colomer and G Roué Leukemia 2014 28: 2049-2059; advance online publication, March 18, 2014; 10.1038/leu.2014.106 Abstract | Full Text |  |  |  | MYELOMA | Quantification of clonal circulating plasma cells in newly diagnosed multiple myeloma: implications for redefining high-risk myelomaW I Gonsalves, S V Rajkumar, V Gupta, W G Morice, M M Timm, P P Singh, A Dispenzieri, F K Buadi, M Q Lacy, P Kapoor, M A Gertz and S K Kumar Leukemia 2014 28: 2060-2065; advance online publication, March 12, 2014; 10.1038/leu.2014.98 Abstract | Full Text |  |  |  | p53 haploinsufficiency and functional abnormalities in multiple myelomaP J Teoh, T H Chung, S Sebastian, S N Choo, J Yan, S B Ng, R Fonseca and W J Chng Leukemia 2014 28: 2066-2074; advance online publication, March 14, 2014; 10.1038/leu.2014.102 Abstract | Full Text |  |  |  | Preserved levels of uninvolved immunoglobulins are independently associated with favorable outcome in patients with symptomatic multiple myelomaE Kastritis, F Zagouri, A Symeonidis, M Roussou, A Sioni, A Pouli, S Delimpasi, E Katodritou, E Michalis, M Michael, E Hatzimichael, A Vassou, P Repousis, A Christophoridou, Z Kartasis, E Stefanoudaki, C Megalakaki, S Giannouli, M-C Kyrtsonis, K Konstantopoulos, M Spyroupoulou-Vlachou, E Terpos and M A Dimopoulos for the Greek Myeloma Study Group Leukemia 2014 28: 2075-2079; advance online publication, March 18, 2014; 10.1038/leu.2014.110 Abstract | Full Text |  |  |  | PKA/AMPK signaling in relation to adiponectin’s antiproliferative effect on multiple myeloma cellsE A Medina, K Oberheu, S R Polusani, V Ortega, G V N Velagaleti and B O Oyajobi Leukemia 2014 28: 2080-2089; advance online publication, March 20, 2014; 10.1038/leu.2014.112 Abstract | Full Text |  | Letters to the Editor | Top |  | ETV6–FLT3 fusion gene-positive, eosinophilia-associated myeloproliferative neoplasm successfully treated with sorafenib and allogeneic stem cell transplantL Falchi, M Mehrotra, K J Newberry, L M Lyle, G Lu, K P Patel, R Luthra, U Popat and S Verstovsek Leukemia 2014 28: 2090-2092; advance online publication, May 23, 2014; 10.1038/leu.2014.168 Full Text |  |  |  | Essential thrombocythemia with high hemoglobin levels according to the revised WHO classificationT Barbui, J Thiele, H M Kvasnicka, A Carobbio, A M Vannucchi and A Tefferi Leukemia 2014 28: 2092-2094; advance online publication, June 3, 2014; 10.1038/leu.2014.175 Full Text |  |  |  | Bone marrow stromal cell-fueled multiple myeloma growth and osteoclastogenesis are sustained by protein kinase CK2S Manni, D Toscani, E Mandato, A Brancalion, L Quotti Tubi, P Macaccaro, A Cabrelle, F Adami, R Zambello, C Gurrieri, G Semenzato, N Giuliani and F Piazza Leukemia 2014 28: 2094-2097; advance online publication, June 4, 2014; 10.1038/leu.2014.178 Full Text |  |  |  | Enhanced generation of cord blood hematopoietic stem and progenitor cells by culture with StemRegenin1 and Delta1Ext-IgGA Dahlberg, C Brashem-Stein, C Delaney and I D Bernstein Leukemia 2014 28: 2097-2101; advance online publication, June 6, 2014; 10.1038/leu.2014.181 Full Text |  |  |  | Effects of the small-molecule inhibitor of integrin α4, TBC3486, on pre-B-ALL cells OPENY T Hsieh, E J Gang, S N Shishido, H N Kim, J Pham, S Khazal, A Osborne, Z A Esguerra, E Kwok, J Jang, H Bonig, R J Biediger, P Vanderslice and Y M Kim Leukemia 2014 28: 2101-2104; advance online publication, June 6, 2014; 10.1038/leu.2014.182 Full Text |  |  |  | MYD88 (L265P) mutation is an independent prognostic factor for outcome in patients with diffuse large B-cell lymphomaC Fernández-Rodríguez, B Bellosillo, M García-García, B Sánchez-González, E Gimeno, M C Vela, S Serrano, C Besses and A Salar Leukemia 2014 28: 2104-2106; advance online publication, June 6, 2014; 10.1038/leu.2014.184 Full Text |  |  |  | Bioinformatic analyses of CALR mutations in myeloproliferative neoplasms support a role in signalingL Eder-Azanza, D Navarro, P Aranaz, F J Novo, N C P Cross and J L Vizmanos Leukemia 2014 28: 2106-2109; advance online publication, June 12, 2014; 10.1038/leu.2014.190 Full Text |  |  |  | B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with dasatinib in cutaneous T-cell lymphoma (CTCL) OPEND L Petersen, T Krejsgaard, J Berthelsen, S Fredholm, A Willerslev-Olsen, N A Sibbesen, C M Bonefeld, M H Andersen, C Francavilla, J V Olsen, T Hu, M Zhang, M A Wasik, C Geisler, A Woetmann and N Odum Leukemia 2014 28: 2109-2112; advance online publication, June 12, 2014; 10.1038/leu.2014.192 Full Text |  |  |  | Predicting multiple myeloma disease activity by analyzing natural calcium isotopic compositionG W Gordon, J Monge, M B Channon, Q Wu, J L Skulan, A D Anbar and R Fonseca Leukemia 2014 28: 2112-2115; advance online publication, June 12, 2014; 10.1038/leu.2014.193 Full Text |  |  |  |  | | Advertisement |  | | |  |  |  |  |  |  |  |  |  | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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