TABLE OF CONTENTS |  |  |  | Volume 110, Issue 8 (1917-2164) Published online 15 April 2014
|  | In this issue Clinical Studies Translational Therapeutics Molecular Diagnostics Genetics & Genomics
Also new today Advance online publication Digital Edition
| |  |  |  | | Advertisement |  | | |  |  | Clinical Studies | Top |  | First-, second-, third-line therapy for mRCC: benchmarks for trial design from the IMDC J J Ko, T K Choueiri, B I Rini, J-L Lee, N Kroeger, S Srinivas, L C Harshman, J J Knox, G A Bjarnason, M J MacKenzie, L Wood, U N Vaishampayan, N Agarwal, S K Pal, M-H Tan, S Y Rha, T Yuasa, F Donskov, A Bamias and D Y C Heng Br J Cancer 2014 110: 1917-1922; advance online publication, April 1, 2014; 10.1038/bjc.2014.25 Abstract | Full Text |  |  |  | A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer R M Glasspool, R Brown, M E Gore, G J S Rustin, I A McNeish, R H Wilson, S Pledge, J Paul, M Mackean, G D Hall, H Gabra, S E R Halford, J Walker, K Appleton, R Ullah and S Kaye Br J Cancer 2014 110: 1923-1929; advance online publication, March 18, 2014; 10.1038/bjc.2014.116 Abstract | Full Text |  |  |  | Prognostic performance of inflammation-based prognostic indices in primary operable non-small cell lung cancer D J Pinato, R J Shiner, M J Seckl, J Stebbing, R Sharma and F A Mauri Br J Cancer 2014 110: 1930-1935; advance online publication, March 25, 2014; 10.1038/bjc.2014.145 Abstract | Full Text |  |  |  | A multicentre randomised controlled trial of reciprocal lung cancer peer review and supported quality improvement: results from the improving lung cancer outcomes project G K Russell, S Jimenez, L Martin, R Stanley, M D Peake and I Woolhouse Br J Cancer 2014 110: 1936-1942; advance online publication, March 20, 2014; 10.1038/bjc.2014.146 Abstract | Full Text |  |  |  | Prognostic nomogram for nonresectable pancreatic cancer treated with gemcitabine-based chemotherapy T Hamada, Y Nakai, H Yasunaga, H Isayama, H Matsui, N Takahara, T Sasaki, K Takagi, T Watanabe, H Yagioka, H Kogure, T Arizumi, N Yamamoto, Y Ito, K Hirano, T Tsujino, M Tada and K Koike Br J Cancer 2014 110: 1943-1949; advance online publication, March 18, 2014; 10.1038/bjc.2014.131 Abstract | Full Text |  |  |  | Adaptive designs for clinical trials assessing biomarker-guided treatment strategies J Wason, A Marshall, J Dunn, R C Stein and N Stallard Br J Cancer 2014 110: 1950-1957; advance online publication, March 25, 2014; 10.1038/bjc.2014.156 Abstract | Full Text |  | Translational Therapeutics | Top |  | Acquisition of epithelial–mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells Q Yang, J Huang, Q Wu, Y Cai, L Zhu, X Lu, S Chen, C Chen and Z Wang Br J Cancer 2014 110: 1958-1967; advance online publication, March 18, 2014; 10.1038/bjc.2014.136 Abstract | Full Text |  |  |  | Clinical significance of p95HER2 overexpression, PTEN loss and PI3K expression in p185HER2-positive metastatic breast cancer patients treated with trastuzumab-based therapies D Tural, S Serdengecti, F Demirelli, T Öztürk, S İlvan, H Turna, M Özgüroglu and E Büyükünal Br J Cancer 2014 110: 1968-1976; advance online publication, March 4, 2014; 10.1038/bjc.2014.72 Abstract | Full Text |  |  |  | Tumour cell retention of rucaparib, sustained PARP inhibition and efficacy of weekly as well as daily schedules J Murray, H Thomas, P Berry, S Kyle, M Patterson, C Jones, G Los, Z Hostomsky, E R Plummer, A V Boddy and N J Curtin Br J Cancer 2014 110: 1977-1984; advance online publication, February 20, 2014; 10.1038/bjc.2014.91 Abstract | Full Text |  |  |  | Biological significance of fluorine-18-α-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancer S Suzuki, K Kaira, Y Ohshima, N S Ishioka, M Sohda, T Yokobori, T Miyazaki, N Oriuchi, H Tominaga, Y Kanai, N Tsukamoto, T Asao, Y Tsushima, T Higuchi, T Oyama and H Kuwano Br J Cancer 2014 110: 1985-1991; advance online publication, March 25, 2014; 10.1038/bjc.2014.142 Abstract | Full Text |  |  |  | Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells Y Zou, F Li, W Hou, P Sampath, Y Zhang and S H Thorne Br J Cancer 2014 110: 1992-1999; advance online publication, March 18, 2014; 10.1038/bjc.2014.140 Abstract | Full Text |  |  |  | Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model A Bhardwaj, S Singh, S K Srivastava, S Arora, S J Hyde, J Andrews, W E Grizzle and A P Singh Br J Cancer 2014 110: 2000-2010; advance online publication, March 18, 2014; 10.1038/bjc.2014.141 Abstract | Full Text |  | Molecular Diagnostics | Top |  | Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer H Q Xi, A Z Cai, X S Wu, J X Cui, W S Shen, S B Bian, N Wang, J Y Li, C R Lu, Z Song, B Wei and L Chen Br J Cancer 2014 110: 2011-2020; advance online publication, March 4, 2014; 10.1038/bjc.2014.112 Abstract | Full Text |  |  |  | Clinical significance of polypeptide N-acetylgalactosaminyl transferase-5 (GalNAc-T5) expression in patients with gastric cancer H He, Z Shen, H Zhang, X Wang, Z Tang, J Xu and Y Sun Br J Cancer 2014 110: 2021-2029; advance online publication, March 11, 2014; 10.1038/bjc.2014.93 Abstract | Full Text |  |  |  | ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer K Shimizu, K Kaira, Y Tomizawa, N Sunaga, O Kawashima, N Oriuchi, H Tominaga, S Nagamori, Y Kanai, M Yamada, T Oyama and I Takeyoshi Br J Cancer 2014 110: 2030-2039; advance online publication, March 6, 2014; 10.1038/bjc.2014.88 Abstract | Full Text |  |  |  | CD74: a new prognostic factor for patients with malignant pleural mesothelioma C Otterstrom, A Soltermann, I Opitz, E Felley-Bosco, W Weder, R A Stahel, F Triponez, J H Robert and V Serre-Beinier Br J Cancer 2014 110: 2040-2046; advance online publication, March 4, 2014; 10.1038/bjc.2014.117 Abstract | Full Text |  |  |  | Clinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma N Sunaga, K Kaira, Y Tomizawa, K Shimizu, H Imai, G Takahashi, S Kakegawa, Y Ohtaki, T Nagashima, N Kasahara, O Kawashima, T Hisada, R Saito and M Yamada Br J Cancer 2014 110: 2047-2053; advance online publication, February 27, 2014; 10.1038/bjc.2014.110 Abstract | Full Text |  |  |  | Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer I Balgkouranidou, M Chimonidou, G Milaki, E G Tsarouxa, S Kakolyris, D R Welch, V Georgoulias and E S Lianidou Br J Cancer 2014 110: 2054-2062; advance online publication, March 18, 2014; 10.1038/bjc.2014.104 Abstract | Full Text |  |  |  | Lack of correlation of stem cell markers in breast cancer stem cells Y Liu, R Nenutil, M V Appleyard, K Murray, M Boylan, A M Thompson and P J Coates Br J Cancer 2014 110: 2063-2071; advance online publication, February 27, 2014; 10.1038/bjc.2014.105 Abstract | Full Text |  |  |  | Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c M K Nygren, C Tekle, V A Ingebrigtsen, R Mäkelä, M Krohn, M R Aure, C E Nunes-Xavier, M Perälä, T Tramm, J Alsner, J Overgaard, J M Nesland, E Borgen, A-L Børresen-Dale, Ø Fodstad, K K Sahlberg and S-K Leivonen Br J Cancer 2014 110: 2072-2080; advance online publication, February 27, 2014; 10.1038/bjc.2014.113 Abstract | Full Text |  |  |  | Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer K Malinowsky, U Nitsche, K-P Janssen, F G Bader, C Späth, E Drecoll, G Keller, H Höfler, J Slotta-Huspenina and K-F Becker Br J Cancer 2014 110: 2081-2089; advance online publication, March 11, 2014; 10.1038/bjc.2014.100 Abstract | Full Text |  |  |  | Biomarker-based prognosis in hepatocellular carcinoma: validation and extension of the BALAD model R Fox, S Berhane, M Teng, T Cox, T Tada, H Toyoda, T Kumada, C Kagebayashi, S Satomura and P J Johnson Br J Cancer 2014 110: 2090-2098; advance online publication, April 1, 2014; 10.1038/bjc.2014.130 Abstract | Full Text |  |  |  | Arachidonic acid induction of Rho-mediated transendothelial migration in prostate cancer M Brown, J-A Roulson, C A Hart, T Tawadros and N W Clarke Br J Cancer 2014 110: 2099-2108; advance online publication, March 4, 2014; 10.1038/bjc.2014.99 Abstract | Full Text |  |  |  | A novel staging model to classify oesophageal squamous cell carcinoma patients in China H Tan, H Zhang, J Xie, B Chen, C Wen, X Guo, Q Zhao, Z Wu, J Shen, J Wu, X Xu, E Li, L Xu and X Wang Br J Cancer 2014 110: 2109-2115; advance online publication, February 25, 2014; 10.1038/bjc.2014.101 Abstract | Full Text |  |  |  | Biliverdin’s regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer J Zheng, D A Nagda, S A Lajud, S Kumar, A Mouchli, O Bezpalko, B W O'Malley, Jr and D Li Br J Cancer 2014 110: 2116-2122; advance online publication, February 25, 2014; 10.1038/bjc.2014.98 Abstract | Full Text |  | Genetics & Genomics | Top |  | LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk S M Tajuddin, A F S Amaral, A F Fernández, S Chanock, D T Silverman, A Tardón, A Carrato, M García-Closas, B P Jackson, E G Toraño, M Márquez, R G Urdinguio, R García-Closas, N Rothman, M Kogevinas, F X Real, M F Fraga, N Malats and for the Spanish Bladder Cancer/EPICURO Study investigators Br J Cancer 2014 110: 2123-2130; advance online publication, March 4, 2014; 10.1038/bjc.2014.67 Abstract | Full Text |  |  |  | Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives P Wongtrakoongate, J Li and P W Andrews Br J Cancer 2014 110: 2131-2138; advance online publication, March 6, 2014; 10.1038/bjc.2014.128 Abstract | Full Text |  |  |  | Impact of HER2 copy number in IHC2+/FISH-amplified breast cancer on outcome of adjuvant trastuzumab treatment in a large UK cancer network A Borley, T Mercer, M Morgan, P Dutton, P Barrett-Lee, M Brunelli and B Jasani Br J Cancer 2014 110: 2139-2143; advance online publication, April 1, 2014; 10.1038/bjc.2014.147 Abstract | Full Text |  |  |  | ERRβ signalling through FST and BCAS2 inhibits cellular proliferation in breast cancer cells D Sengupta, D K Bhargava, A Dixit, B S Sahoo, S Biswas, G Biswas and S K Mishra Br J Cancer 2014 110: 2144-2158; advance online publication, March 25, 2014; 10.1038/bjc.2014.53 Abstract | Full Text |  |  |  | Prognostic impact of genomic instability in colorectal cancer T S Hveem, M A Merok, M E Pretorius, M Novelli, M S Bævre, O H Sjo, N Clinch, K Liestøl, A Svindland, R A Lothe, A Nesbakken and H E Danielsen Br J Cancer 2014 110: 2159-2164; advance online publication, March 18, 2014; 10.1038/bjc.2014.133 Abstract | Full Text |  |  |  |  | | Advertisement |  | Don't miss out! 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