Molecular Systems Biology - New articles published 14 August 2012

Latest Articles 14th August 2012   Featured Article Research Articles   Web feeds About Open access Advertisement 'How to get published?' session at ICSB 2012, Toronto, 19-23 August The session will be hosted by the Chief Editor of Molecular Systems Biology and take place on Tuesday, August 21 @12:00 pm, in the Carlu (bring along your conference lunch). Invitation is open to all attendees!  Find out more     Featured Article Mapping the human phosphatome on growth pathways Phosphatases control cell growth by a variety of mechanisms. A novel strategy is presented that combines multiparametric analysis of cell perturbations with logic modeling to achieve a detailed mapping of human phosphatase function on growth pathways. Francesca Sacco, Pier Federico Gherardini, Serena Paoluzi, Julio Saez-Rodriguez, Manuela Helmer-Citterich, Antonella Ragnini-Wilson, Luisa Castagnoli & Gianni Cesareni Molecular Systems Biology 8:603; doi:10.1038/msb.2012.36; published 14 August 2012 Full Text | PDF | Supp. Inf. | Review Process Research Articles Dissecting sources of quantitative gene expression pattern divergence between Drosophila species The function of a transcriptional circuit is compared in three closely related species of Drosophila. Using quantitative imaging of gene expression, targeted transgenic reporter fly lines, and a computational framework, the sources of their differing expression outputs are identified. Zeba Wunderlich, Meghan D Bragdon, Kelly B Eckenrode, Tara Lydiard-Martin, Sivanne Pearl-Waserman & Angela H DePace Molecular Systems Biology 8:604; doi:10.1038/msb.2012.35; published 14 August 2012 Full Text | PDF | Supp. Inf. | Review Process Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS A novel strategy for the quantitative measurement of allele-specific protein expression is used to infer the contributions of cis- and trans-acting factors influencing the divergence of protein levels between yeast species. Zia Khan, Joshua S Bloom, Sasan Amini, Mona Singh, David H Perlman, Amy A Caudy & Leonid Kruglyak Molecular Systems Biology 8:602; doi:10.1038/msb.2012.34; published 14 August 2012 Full Text | PDF | Supp. Inf. | Review Process

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