| | | | Weekly Content Alert
| | 14 August 2012 | | Featured image: | | | | Sandström et al. use roll-coating apparatus to produce light-emitting electrochemical cells under ambient conditions. |
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| | | Advertisement | | | | | | Latest Articles | View all Articles | | | Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers | | Maxime Zoenen, Eneko Urizar, Stéphane Swillens, Gilbert Vassart and Sabine Costagliola | | Glycoprotein hormone receptors show negative cooperativity following a single molecule of agonist binding to each receptor dimer. Here, constitutively active receptors are shown to display less cooperative allosteric regulation, suggesting a direct relationship between conformational changes in the transmembrane domain and allosteric behaviour of the receptor dimers. | | 14 Aug | Nat Commun 3:1007 doi:10.1038/ncomms1991 (2012) | | Biological sciences Biophysics | | | | Abstract | Full Text | PDF (812 kB) | Supplementary Information |
TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export | | Nicolas Viphakone, Guillaume M. Hautbergue, Matthew Walsh, Chung-Te Chang, Arthur Holland, Eric G. Folco, Robin Reed and Stuart A. Wilson | | The TREX complex and Nxf1 are involved in the export of mRNA from the nucleus but the precise molecular function of TREX is unclear. Here, the TREX components Aly and Thoc5 are shown to bind to Nxf1 resulting in a change in Nxf1 conformation that permits binding to mRNA and nuclear export. | | 14 Aug | Nat Commun 3:1006 doi:10.1038/ncomms2005 (2012) | | Biological sciences Cell biology | | Molecular biology | | Abstract | Full Text | PDF (1,924 kB) | Supplementary Information |
Antenna electrodes for controlling electroluminescence | | Kevin C.Y. Huang, Min-Kyo Seo, Yijie Huo, Tomas Sarmiento, James S. Harris and Mark L. Brongersma | | Metallic nanoantennas can be used to enhance and tailor the photoluminescence effects in small-scale devices. Huang et al. design combined nanoantenna electrodes for quantum well nanoscale light-emitting diodes, to both inject charge and control the electroluminescence properties. | | 14 Aug | Nat Commun 3:1005 doi:10.1038/ncomms1985 (2012) | | Physical sciences Applied physics | | Nanotechnology Optical physics | | Abstract | Full Text | PDF (661 kB) | Supplementary Information |
DNA replication timing and selection shape the landscape of nucleotide variation in cancer genomes | | Yong H Woo and Wen-Hsiung Li | | Cancer cells form by somatic mutations and natural selection, but how these factors affect tumorigenesis is not clear. Here, somatic mutations are characterized in human cancer genomes, revealing that DNA replication timing influences the frequency of single-nucleotide variants in different genomic regions. | | 14 Aug | Nat Commun 3:1004 doi:10.1038/ncomms1982 (2012) | | Biological sciences Cancer | | Genetics | | Abstract | Full Text | PDF (440 kB) | Supplementary Information |
Ambient fabrication of flexible and large-area organic light-emitting devices using slot-die coating OPEN | | Andreas Sandström, Henrik F. Dam, Frederik C. Krebs and Ludvig Edman | | Light-emitting electrochromic cells are a promising alternative to organic light-emitting diodes, as their performance is less sensitive to fabrication conditions. Here, a roll-to-roll compatible fabrication of such devices is presented, demonstrating large-area continuous production in ambient conditions. | | 14 Aug | Nat Commun 3:1002 doi:10.1038/ncomms2002 (2012) | | Physical sciences Applied physics | | Materials science Optical physics | | | | Abstract | Full Text | PDF (724 kB) |
Stirring competes with chemical induction in chiral selection of soft matter aggregates | | Núria Petit-Garrido, Josep Claret, Jordi Ignés-Mullol and Francesc Sagués | | Chirality can be induced both by physical forces and by chemical induction processes. Here, a self-assembled system is reported in which chiral selection is controlled by the combined action of a chiral dopant and vortical stirring, which can act either constructively or destructively. | | 14 Aug | Nat Commun 3:1001 doi:10.1038/ncomms1987 (2012) | | Chemical sciences Physical chemistry | | Abstract | Full Text | PDF (759 kB) |
FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage | | Young Min Chung, See-Hyoung Park, Wen-Bin Tsai, Shih-Ya Wang, Masa-Aki Ikeda, Jonathan S. Berek, David J. Chen and Mickey C.-T. Hu | | The protein ataxia-telangiectasia mutated (ATM) detects DNA damage and can trigger cellular apoptosis, but how this process is regulated at the molecular level is unclear. Here, Chung et al. show that the transcription factor FOXO3 controls the formation of ATM-containing signalling complexes at sites of DNA damage that trigger apoptosis. | | 14 Aug | Nat Commun 3:1000 doi:10.1038/ncomms2008 (2012) | | Biological sciences Cancer | | Cell biology | | Abstract | Full Text | PDF (1,348 kB) | Supplementary Information |
Laser-induced ultrafast demagnetization in the presence of a nanoscale magnetic domain network | | Boris Vodungbo, Julien Gautier, Guillaume Lambert, Anna Barszczak Sardinha, Magali Lozano, Stéphane Sebban, Mathieu Ducousso, Willem Boutu, Kaigong Li, Bharati Tudu, Marina Tortarolo, Ranjit Hawaldar, Renaud Delaunay, Victor López-Flores, Jacek Arabski, Christine Boeglin, Hamed Merdji, Philippe Zeitoun and Jan Lüning | | Understanding ultrafast demagnetisation is key to manipulating magnetic structures on fast timescales, yet laser sources limit the attainable spatial resolution. Here, a soft X-ray high harmonic source enables a high temporal and spatial resolution study of domain demagnetisation in [Co/Pt]30 multilayer films. | | 14 Aug | Nat Commun 3:999 doi:10.1038/ncomms2007 (2012) | | Physical sciences Condensed matter | | Materials science Optical physics | | | | Abstract | Full Text | PDF (749 kB) | Supplementary Information |
Three-dimensional orientation-unlimited polarization encryption by a single optically configured vectorial beam | | Xiangping Li, Tzu-Hsiang Lan, Chung-Hao Tien and Min Gu | | Generating arbitrary orientation of light polarization has been an elusive goal, yet it is important to light interactions with nano-objects. By combining azimuthally and radially polarized beams, Li et al. overcome this obstacle and demonstrate its use for polarization-based encryption with gold nanorods. | | 14 Aug | Nat Commun 3:998 doi:10.1038/ncomms2006 (2012) | | Physical sciences Applied physics | | Nanotechnology Optical physics | | Abstract | Full Text | PDF (669 kB) | Supplementary Information |
Composite pulses for robust universal control of singlet–triplet qubits | | Xin Wang, Lev S. Bishop, J.P. Kestner, Edwin Barnes, Kai Sun and S. Das Sarma | | Precise qubit manipulation is essential in quantum computation; however errors can occur from fluctuations in the magnetic field. Wang et al. propose a robust scheme for universal control of qubits in a semiconductor double quantum dot, cancelling leading orders of error in field gradient variation. | | 14 Aug | Nat Commun 3:997 doi:10.1038/ncomms2003 (2012) | | Physical sciences Condensed matter | | Theoretical physics | | Abstract | Full Text | PDF (472 kB) | Supplementary Information |
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