Tuesday, August 14, 2012

Nature Communications - 14 August 2012

 
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14 August 2012
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Sandström et al. use roll-coating apparatus to produce light-emitting electrochemical cells under ambient conditions.
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Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers
Maxime Zoenen, Eneko Urizar, Stéphane Swillens, Gilbert Vassart and Sabine Costagliola
Glycoprotein hormone receptors show negative cooperativity following a single molecule of agonist binding to each receptor dimer. Here, constitutively active receptors are shown to display less cooperative allosteric regulation, suggesting a direct relationship between conformational changes in the transmembrane domain and allosteric behaviour of the receptor dimers.
14 Aug | Nat Commun 3:1007 doi:10.1038/ncomms1991 (2012)
Biological sciences Biophysics 
Abstract | Full Text | PDF (812 kB) |
Supplementary Information

TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export
Nicolas Viphakone, Guillaume M. Hautbergue, Matthew Walsh, Chung-Te Chang, Arthur Holland, Eric G. Folco, Robin Reed and Stuart A. Wilson
The TREX complex and Nxf1 are involved in the export of mRNA from the nucleus but the precise molecular function of TREX is unclear. Here, the TREX components Aly and Thoc5 are shown to bind to Nxf1 resulting in a change in Nxf1 conformation that permits binding to mRNA and nuclear export.
14 Aug | Nat Commun 3:1006 doi:10.1038/ncomms2005 (2012)
Biological sciences Cell biology 
Molecular biology 
Abstract | Full Text | PDF (1,924 kB) |
Supplementary Information

Antenna electrodes for controlling electroluminescence
Kevin C.Y. Huang, Min-Kyo Seo, Yijie Huo, Tomas Sarmiento, James S. Harris and Mark L. Brongersma
Metallic nanoantennas can be used to enhance and tailor the photoluminescence effects in small-scale devices. Huang et al. design combined nanoantenna electrodes for quantum well nanoscale light-emitting diodes, to both inject charge and control the electroluminescence properties.
14 Aug | Nat Commun 3:1005 doi:10.1038/ncomms1985 (2012)
Physical sciences Applied physics 
Nanotechnology Optical physics 
Abstract | Full Text | PDF (661 kB) |
Supplementary Information

DNA replication timing and selection shape the landscape of nucleotide variation in cancer genomes
Yong H Woo and Wen-Hsiung Li
Cancer cells form by somatic mutations and natural selection, but how these factors affect tumorigenesis is not clear. Here, somatic mutations are characterized in human cancer genomes, revealing that DNA replication timing influences the frequency of single-nucleotide variants in different genomic regions.
14 Aug | Nat Commun 3:1004 doi:10.1038/ncomms1982 (2012)
Biological sciences Cancer 
Genetics
Abstract | Full Text | PDF (440 kB) |
Supplementary Information

Mechanism of resilin elasticity
Guokui Qin, Xiao Hu, Peggy Cebe and David L. Kaplan
Resilin is a polymeric elastic protein that is important for the flight and jumping of insects. Here, the structure-function relationships of Drosophila resilin are investigated, and a mechanical model is proposed to account for its elasticity.
14 Aug | Nat Commun 3:1003 doi:10.1038/ncomms2004 (2012)
Biological sciences Biophysics Materials science
Abstract | Full Text | PDF (1,540 kB) |
Supplementary Information

Ambient fabrication of flexible and large-area organic light-emitting devices using slot-die coating OPEN
Andreas Sandström, Henrik F. Dam, Frederik C. Krebs and Ludvig Edman
Light-emitting electrochromic cells are a promising alternative to organic light-emitting diodes, as their performance is less sensitive to fabrication conditions. Here, a roll-to-roll compatible fabrication of such devices is presented, demonstrating large-area continuous production in ambient conditions.
14 Aug | Nat Commun 3:1002 doi:10.1038/ncomms2002 (2012)
Physical sciences Applied physics 
Materials science Optical physics 
Abstract | Full Text | PDF (724 kB)

Stirring competes with chemical induction in chiral selection of soft matter aggregates
Núria Petit-Garrido, Josep Claret, Jordi Ignés-Mullol and Francesc Sagués
Chirality can be induced both by physical forces and by chemical induction processes. Here, a self-assembled system is reported in which chiral selection is controlled by the combined action of a chiral dopant and vortical stirring, which can act either constructively or destructively.
14 Aug | Nat Commun 3:1001 doi:10.1038/ncomms1987 (2012)
Chemical sciences Physical chemistry 
Abstract | Full Text | PDF (759 kB)

FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage
Young Min Chung, See-Hyoung Park, Wen-Bin Tsai, Shih-Ya Wang, Masa-Aki Ikeda, Jonathan S. Berek, David J. Chen and Mickey C.-T. Hu
The protein ataxia-telangiectasia mutated (ATM) detects DNA damage and can trigger cellular apoptosis, but how this process is regulated at the molecular level is unclear. Here, Chung et al. show that the transcription factor FOXO3 controls the formation of ATM-containing signalling complexes at sites of DNA damage that trigger apoptosis.
14 Aug | Nat Commun 3:1000 doi:10.1038/ncomms2008 (2012)
Biological sciences Cancer 
Cell biology 
Abstract | Full Text | PDF (1,348 kB) |
Supplementary Information

Laser-induced ultrafast demagnetization in the presence of a nanoscale magnetic domain network
Boris Vodungbo, Julien Gautier, Guillaume Lambert, Anna Barszczak Sardinha, Magali Lozano, Stéphane Sebban, Mathieu Ducousso, Willem Boutu, Kaigong Li, Bharati Tudu, Marina Tortarolo, Ranjit Hawaldar, Renaud Delaunay, Victor López-Flores, Jacek Arabski, Christine Boeglin, Hamed Merdji, Philippe Zeitoun and Jan Lüning
Understanding ultrafast demagnetisation is key to manipulating magnetic structures on fast timescales, yet laser sources limit the attainable spatial resolution. Here, a soft X-ray high harmonic source enables a high temporal and spatial resolution study of domain demagnetisation in [Co/Pt]30 multilayer films.
14 Aug | Nat Commun 3:999 doi:10.1038/ncomms2007 (2012)
Physical sciences Condensed matter 
Materials science Optical physics 
Abstract | Full Text | PDF (749 kB) |
Supplementary Information

Three-dimensional orientation-unlimited polarization encryption by a single optically configured vectorial beam
Xiangping Li, Tzu-Hsiang Lan, Chung-Hao Tien and Min Gu
Generating arbitrary orientation of light polarization has been an elusive goal, yet it is important to light interactions with nano-objects. By combining azimuthally and radially polarized beams, Li et al. overcome this obstacle and demonstrate its use for polarization-based encryption with gold nanorods.
14 Aug | Nat Commun 3:998 doi:10.1038/ncomms2006 (2012)
Physical sciences Applied physics 
Nanotechnology Optical physics 
Abstract | Full Text | PDF (669 kB) |
Supplementary Information

Composite pulses for robust universal control of singlet–triplet qubits
Xin Wang, Lev S. Bishop, J.P. Kestner, Edwin Barnes, Kai Sun and S. Das Sarma
Precise qubit manipulation is essential in quantum computation; however errors can occur from fluctuations in the magnetic field. Wang et al. propose a robust scheme for universal control of qubits in a semiconductor double quantum dot, cancelling leading orders of error in field gradient variation.
14 Aug | Nat Commun 3:997 doi:10.1038/ncomms2003 (2012)
Physical sciences Condensed matter 
Theoretical physics
Abstract | Full Text | PDF (472 kB) |
Supplementary Information
 
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