Nature Reviews Neuroscience contents October 2018 Volume 19 Number 10

If you are unable to see the message below, click here to view.

TABLE OF CONTENTS October 2018 Volume 19, Issue 10 Research Highlights Reviews Correspondence   Research Highlights   Auditory advances Katherine Whalley p579 | doi:10.1038/s41583-018-0052-x Spontaneous activity in the developing auditory system is maintained by a homeostatic mechanism and is important for cochlear neuron subtype specification. PDF   Concentrating on the claustrum Natasha Bray pp580 - 581 | doi:10.1038/s41583-018-0056-6 Two studies show that the claustrum delivers inhibition to different parts of the cortex — the prefrontal cortex and auditory cortex. PDF   Receptor replacement Darran Yates pp580 - 581 | doi:10.1038/s41583-018-0060-x Mice receiving autoantibodies against the GluA2 AMPA receptor subunit from individuals with autoimmune encephalitis exhibit changes in AMPA receptor subunit composition and impaired synaptic plasticity and memory. PDF   Planning a path Sian Lewis p581 | doi:10.1038/s41583-018-0061-9 PDF   Catching waves Sian Lewis p581 | doi:10.1038/s41583-018-0062-8 PDF   Untangling tau structure Sian Lewis p581 | doi:10.1038/s41583-018-0063-7 PDF   Novel inhibition Sian Lewis p581 | doi:10.1038/s41583-018-0064-6 PDF   Reviews   Rodent models for Alzheimer disease    Jürgen Götz, Liviu-Gabriel Bodea & Michel Goedert pp583 - 598 | doi:10.1038/s41583-018-0054-8 Rodent models are extensively used to investigate the pathophysiology of Alzheimer disease. In this Review, Götz, Bodea and Goedert critically examine the approaches that have been adopted to generate rodent Alzheimer disease models and touch on some of the lessons that have been learned from their use. Full Text | PDF   Multiple sclerosis and cognition: synaptic failure and network dysfunction    Massimiliano Di Filippo, Emilio Portaccio, Andrea Mancini & Paolo Calabresi pp599 - 609 | doi:10.1038/s41583-018-0053-9 Cognitive impairment is a key feature of multiple sclerosis (MS). Di Filippo and colleagues provide an overview of the cognitive domains and brain regions that are affected in MS, with a focus on potential hippocampal mechanisms underlying learning and memory deficits in this disease. Full Text | PDF   Inflammasome signalling in brain function and neurodegenerative disease    Michael T. Heneka, Róisín M. McManus & Eicke Latz pp610 - 621 | doi:10.1038/s41583-018-0055-7 Inflammasomes are pro-inflammatory protein complexes that become activated in a range of neurodegenerative conditions. In this review, Heneka and colleagues discuss recent findings that provide fresh insights on the role of inflammasomes across cell types and disease states in the brain. Full Text | PDF   Microglial signatures and their role in health and disease    Oleg Butovsky & Howard L. Weiner pp622 - 635 | doi:10.1038/s41583-018-0057-5 Technological advances have allowed the molecular ‘signatures’ of microglia to be characterized, providing insight into their roles in CNS function. Weiner and Butovsky discuss the plasticity of these signatures in health and disease and consider the mechanisms underlying their establishment, maintenance and regulation. Full Text | PDF   Advertisement Do you have a career question?  The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud. Listen today >>   Correspondence   Can neocortical feedback alter the sign of plasticity?    Blake A. Richards & Timothy P. Lillicrap p636 | doi:10.1038/s41583-018-0049-5 Full Text | PDF   Reply to ‘Can neocortical feedback alter the sign of plasticity?’    Pieter R. Roelfsema & Anthony Holtmaat pp637 - 638 | doi:10.1038/s41583-018-0048-6 Full Text | PDF   Advertisement Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. Click here to sign up.   Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount (You will need to log in to be recognised as a nature.com registrant) For further technical assistance, please contact our registration department For print subscription enquiries, please contact our subscription department For other enquiries, please contact our customer feedback department Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA Springer Nature's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW. Nature is part of Springer Nature. © 2018 Springer Nature Limited. All rights reserved.