Nature Reviews Genetics Contents October 2018 Volume 19 Number 10

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Advertisement Do you have a career question?  The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud.  Listen today!  TABLE OF CONTENTS October 2018 Volume 19, Issue 10 Research Highlights Reviews Consensus Statement   Advertisement Does Your Taq Need to Go? Upgrade from standard Taq to GoTaq® G2 Hot Start and enjoy the convenience of room-temperature setup and higher yield, sensitivity and specificity. Compare your current Taq to GoTaq® G2 Hot Start and submit your data. You'll be entered to win monthly prizes and an Eppendorf thermal cycler.  Request free sample   Research Highlights   Dynamic RNAs in sperm shape embryo development Ross Cloney p591 | doi:10.1038/s41576-018-0042-x Two studies published in the journal Developmental Cell suggest that changes to the RNA payload of sperm that occur during maturation in the epididymis help ensure successful embryo development in mice. PDF   Evolution of eusociality Linda Koch p592 | doi:10.1038/s41576-018-0044-8 Insulin signalling underlies the evolution and regulation of eusocial behaviours in ants, posits a recent study in Science. PDF   FOXP2 tells a cautionary tale Rebecca Furlong pp592 - 593 | doi:10.1038/s41576-018-0046-6 A study in Cell challenges the existing notion of the evolution of FOXP2 as a human-specific language gene. PDF   Lessons from 1 million genomes Michelle Trenkmann pp592 - 593 | doi:10.1038/s41576-018-0047-5 A Nature Genetics study reports the findings of a genome-wide associationstudy of educational attainment in 1.1 million individuals. PDF   Transcriptomics in intact tissues Linda Koch p593 | doi:10.1038/s41576-018-0045-7 A new RNA sequencing technology reported in Science uses hydrogel-tissue chemistry to enable gene expression profiling in intact tissues. PDF   Nature Reviews Genetics JOBS of the week Research Fellow Dana-Farber Cancer Institute (DFCI) Postdoctoral Fellow / Physiology - 18000001DU The University of Tennessee Health Science Center (UTHSC) Tenure Track Faculty Positions Michigan State University Faculty Positions Available in Southwest University Southwest University (SWU) Faculty and Postdoctoral Positions at the Institute of Technological Sciences, Wuhan University Wuhan University More Science jobs from Nature Reviews Genetics EVENT Systems Genetics of Aging Symposium 10.10.18 Farmington, USA More science events from Reviews   Stem cell bioengineering: building from stem cell biology    Mukul Tewary, Nika Shakiba & Peter W. Zandstra pp595 - 614 | doi:10.1038/s41576-018-0040-z This Review discusses how stem cell bioengineering can advance regenerative medicine by giving insight into the design principles that underlie different levels of stem cell systems — from the inner circuitry in single cells and the stem cell niche to systemic interactions between organs and tissues. Full Text | PDF Collection: Stem cells from development to the clinic   High-throughput determination of RNA structures    Eric J. Strobel, Angela M Yu & Julius B. Lucks pp615 - 634 | doi:10.1038/s41576-018-0034-x High-throughput sequencing technology is enabling the structures of RNA to be determined on an unprecedented scale, providing insights into the relationship between the structures adopted by RNAs and the functions they perform in the cell. Full Text | PDF   Cytonuclear integration and co-evolution    Daniel B. Sloan, Jessica M. Warren, Alissa M. Williams, Zhiqiang Wu, Salah E. Abdel-Ghany et al. pp635 - 648 | doi:10.1038/s41576-018-0035-9 Eukaryotic cells must regulate not only their nuclear genomes but also the intimate functional interplay with organelle genomes, such as those in mitochondria and plastids. This Review discusses the functional and evolutionary implications of cellular genomes being partitioned between the nucleus and organelles, including the translocation of genes and gene products, chimeric enzyme complexes and insights into molecular co-evolution. Full Text | PDF   Consensus Statement   Diagnosis and management of Cornelia de Lange syndrome: first international consensus statement    Antonie D. Kline, Joanna F. Moss, Angelo Selicorni, Anne-Marie Bisgaard, Matthew A. Deardorff et al. pp649 - 666 | doi:10.1038/s41576-018-0031-0 Cornelia de Lange syndrome is a genetic disorder affecting multiple organ systems that exhibits great phenotypic heterogeneity. This Consensus Statement summarizes recommendations for the diagnosis and management of patients with Cornelia de Lange syndrome. Full Text | PDF   Advertisement Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. Click here to sign up.   Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

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