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Cell Death and Disease - Table of Contents alert Volume 9, August 2018

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Cell Death & Disease
TABLE OF CONTENTS

Volume 9 (August 2018)

In this issue
Article
Review Article
Comment
Correction
 

Article

 

A fully defined static suspension culture system for large-scale human embryonic stem cell production

Xia Li, Ruoyu Ma, Qi Gu, Lingmin Liang, Lei Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0863-8

Abstract | Full Text

Long non-coding RNA SNHG5 promotes human hepatocellular carcinoma progression by regulating miR-26a-5p/GSK3β signal pathway

Yarui Li, Dan Guo, Yan Zhao, Mudan Ren, Guifang Lu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0882-5

Abstract | Full Text

Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells

Riccardo Cristofani, Marina Montagnani Marelli, Maria Elena Cicardi, Fabrizio Fontana, Monica Marzagalli et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0866-5

Abstract | Full Text

CD59 is a potential biomarker of esophageal squamous cell carcinoma radioresistance by affecting DNA repair

Yuzhen Zhou, Li Chu, Qi Wang, Weixing Dai, Xiaozhou Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0895-0

Abstract | Full Text

MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors

Marialaura Petroni, Francesca Sardina, Paola Infante, Armando Bartolazzi, Erica Locatelli et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0924-z

Abstract | Full Text

High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling

Donghyeok Kim, Bo-hyun Choi, In-geun Ryoo & Mi-Kyoung Kwak

Cell Death & Disease 2018 9: 10.1038/s41419-018-0903-4

Abstract | Full Text

Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

Ni Ni Moe Myint, Ajay M. Verma, Daniel Fernandez-Garcia, Panchali Sarmah, Patrick S. Tarpey et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0934-x

Abstract | Full Text

Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation

Qi Lv, Can Shi, Simiao Qiao, Na Cao, Chunge Guan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0814-4

Abstract | Full Text

SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency

Ah-Young Kim, Eun-Mi Lee, Eun-Joo Lee, Jae-Hong Kim, Kyoungho Suk et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0920-3

Abstract | Full Text

TRMP, a p53-inducible long noncoding RNA, regulates G1/S cell cycle progression by modulating IRES-dependent p27 translation

Yang Yang, Chenfeng Wang, Kailiang Zhao, Guang Zhang, Decai Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0884-3

Abstract | Full Text

Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation

Hiroshi Kuribayashi, Yukihiro Baba, Toshiro Iwagawa, Eisuke Arai, Akira Murakami et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0907-0

Abstract | Full Text

Enhanced articular cartilage regeneration with SIRT1-activated MSCs using gelatin-based hydrogel

Seong Mi Choi, Kyoung-Mi Lee, Seung Bae Ryu, Yoo Jung Park, Yeok Gu Hwang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0914-1

Abstract | Full Text

Novel β-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer

Su Jin Kim, Tae Hwan Noh, Sujin Son, Do Hyun Kim, Wooseong Kim et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0942-x

Abstract | Full Text

The activation of microRNA-520h–associated TGF-β1/c-Myb/Smad7 axis promotes epithelial ovarian cancer progression

Jing Zhang, Wenxue Liu, Fangqian Shen, Xiaoling Ma, Xiaorui Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0946-6

Abstract | Full Text

Human menstrual blood-derived stem cells promote functional recovery in a rat spinal cord hemisection model

Qinfeng Wu, Qinghua Wang, Zhangjie Li, Xiangzhe Li, Jing Zang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0847-8

Abstract | Full Text

The bHLH transcription factor DEC1 promotes thyroid cancer aggressiveness by the interplay with NOTCH1

Cristina Gallo, Valentina Fragliasso, Benedetta Donati, Federica Torricelli, Annalisa Tameni et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0933-y

Abstract | Full Text

Alpha-6 integrin promotes radioresistance of glioblastoma by modulating DNA damage response and the transcription factor Zeb1

Aline Kowalski-Chauvel, Anouchka Modesto, Valerie Gouaze-andersson, Laurent Baricault, Julia Gilhodes et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0853-x

Abstract | Full Text

Foot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression

Huan-Huan Feng, Zi-Xiang Zhu, Wei-Jun Cao, Fan Yang, Xiang-Le Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0940-z

Abstract | Full Text

Autophagy exacerbates electrical remodeling in atrial fibrillation by ubiquitin-dependent degradation of L-type calcium channel

Yue Yuan, Jing Zhao, Yongtai Gong, Dingyu Wang, Xiaoyu Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0860-y

Abstract | Full Text

CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling

Neng Wang, Weiping Liu, Yifeng Zheng, Shengqi Wang, Bowen Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0876-3

Abstract | Full Text

Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness

Shu-Huei Cho, I-Ying Kuo, Pei-Jung Frank Lu, Hong-Tai Tzeng, Wu-Wei Lai et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0915-0

Abstract | Full Text

DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis

Jing Zhou, Hao Liu, Lian Zhang, Xin Liu, Chundong Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0883-4

Abstract | Full Text

HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis

Xusheng Ding, Jun Ji, Jinling Jiang, Qu Cai, Chao Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0922-1

Abstract | Full Text

PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons

Duk-shin Lee & Ji-Eun Kim

Cell Death & Disease 2018 9: 10.1038/s41419-018-0910-5

Abstract | Full Text

The expression and function of RASAL2 in renal cell carcinoma angiogenesis

Ke Hui, Yangyang Yue, Shiqi Wu, Yanan Gu, Bing Guan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0898-x

Abstract | Full Text

Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling

Cheong-Meng Chong, Minjing Ke, Yuan Tan, Zhijian Huang, Ke Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0945-7

Abstract | Full Text

PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice

No-Joon Song, Seo-Hyuk Chang, Suji Kim, Vanja Panic, Byung-Hyun Jang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0904-3

Abstract | Full Text

Zinc induces CDK5 activation and neuronal death through CDK5-Tyr15 phosphorylation in ischemic stroke

Qing-Zhang Tuo, Zhen-Yu Liuyang, Peng Lei, Xiong Yan, Yang-Ping Shentu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0929-7

Abstract | Full Text

Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells

Tae Woo Kim, Seon Young Lee, Mia Kim, Chunhoo Cheon & Seong-Gyu Ko

Cell Death & Disease 2018 9: 10.1038/s41419-018-0930-1

Abstract | Full Text

Release of c-FLIP brake selectively sensitizes human cancer cells to TLR3-mediated apoptosis

Lugain Alkurdi, François Virard, Béatrice Vanbervliet, Kathrin Weber, Florent Toscano et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0850-0

Abstract | Full Text

RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD

Hui Chen, Yulu Fang, Jianfeng Wu, Hong Chen, Zhenhuan Zou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0936-8

Abstract | Full Text

Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury

Yong-Yue Gao, Zi-Huan Zhang, Zong Zhuang, Yue Lu, Ling-Yun Wu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0939-5

Abstract | Full Text

ARD1 contributes to IKKβ-mediated breast cancer tumorigenesis

Yu Zhang, Hang Zhou, Yongjun Tao, Xingyu Liu, Zhu Yuan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0921-2

Abstract | Full Text

Nuclear YAP localization as a key regulator of podocyte function

Jakob Bonse, Dirk Oliver Wennmann, Joachim Kremerskothen, Thomas Weide, Ulf Michgehl et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0878-1

Abstract | Full Text

ID1-induced p16/IL6 axis activation contributes to the resistant of hepatocellular carcinoma cells to sorafenib

Lei-lei Niu, Chuan-le Cheng, Ming-Yue Li, Sheng-li Yang, Bao-guang Hu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0926-x

Abstract | Full Text

Essential role of Ahnak in adipocyte differentiation leading to the transcriptional regulation of Bmpr1α expression

Jong Kyu Woo, Jae Hoon Shin, Seo Hyun Lee, Hun-Min Park, Soo Young Cho et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0873-6

Abstract | Full Text

Novel AF1q/MLLT11 favorably affects imatinib resistance and cell survival in chronic myeloid leukemia

Wei Li, Min Ji, Fei Lu, Yihua Pang, Xin Dong et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0900-7

Abstract | Full Text

Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/β-catenin signal pathway in hepatocellular carcinoma

Yufeng Wang, Liankang Sun, Liang Wang, Zhikui Liu, Qing Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0937-7

Abstract | Full Text

Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy

Zhengyu Jiang, Lulong Bo, Yan Meng, Chen Wang, Tianxing Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0838-9

Abstract | Full Text

Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53

Mannu K. Walia, Scott Taylor, Patricia W. M. Ho, T. John Martin & Carl R. Walkley

Cell Death & Disease 2018 9: 10.1038/s41419-018-0944-8

Abstract | Full Text

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

Matheus Dyczynski, Mattias Vesterlund, Ann-Charlotte Björklund, Vasilios Zachariadis, Jerry Janssen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0625-7

Abstract | Full Text

Long noncoding RNA NEAT1, regulated by LIN28B, promotes cell proliferation and migration through sponging miR-506 in high-grade serous ovarian cancer

Wu Yong, Deng Yu, Zhu Jun, Duan Yachen, Weng Weiwei et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0908-z

Abstract | Full Text

Exosomal miR-21-5p derived from gastric cancer promotes peritoneal metastasis via mesothelial-to-mesenchymal transition

Qiang Li, Bowen Li, Qing Li, Song Wei, Zhongyuan He et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0928-8

Abstract | Full Text

PARP12 (ARTD12) suppresses hepatocellular carcinoma metastasis through interacting with FHL2 and regulating its stability

Changjuan Shao, Yangyang Qiu, Juan Liu, Huan Feng, Suqin Shen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0906-1

Abstract | Full Text

BAG3 regulates stability of IL-8 mRNA via interplay between HuR and miR-4312 in PDACs

Chao Li, Jing-Yi Jiang, Jia-Mei Wang, Jia Sun, Ming-Xin An et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0874-5

Abstract | Full Text

Specific inhibition of ADAM17/TACE promotes neurogenesis in the injured motor cortex

Noelia Geribaldi-Doldán, Manuel Carrasco, Maribel Murillo-Carretero, Samuel Domínguez-García, Francisco J. García-Cózar et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0913-2

Abstract | Full Text

JAM-A knockdown accelerates the proliferation and migration of human keratinocytes, and improves wound healing in rats via FAK/Erk signaling

Yunchuan Wang, Jianping Zheng, Yue Han, Yijie Zhang, Linlin Su et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0941-y

Abstract | Full Text

TGF-β1-SOX9 axis-inducible COL10A1 promotes invasion and metastasis in gastric cancer via epithelial-to-mesenchymal transition

Tingting Li, Haipeng Huang, Guangyao Shi, Liying Zhao, Tuanjie Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0877-2

Abstract | Full Text

MALAT1miR663a negative feedback loop in colon cancer cell functions through direct miRNA–lncRNA binding

Wei Tian, Yantao Du, Yuwan Ma, Liankun Gu, Jing Zhou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0925-y

Abstract | Full Text

JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism

Qin Wei, Baoyong Zhou, Gangyi Yang, Wenjing Hu, Lili Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0923-0

Abstract | Full Text

TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation

Gang Zheng, Yu Zhan, Xiaobin Li, Zongyou Pan, Fanghong Zheng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0909-y

Abstract | Full Text

Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury

Céline Descloux, Vanessa Ginet, Coralie Rummel, Anita C. Truttmann & Julien Puyal

Cell Death & Disease 2018 9: 10.1038/s41419-018-0916-z

Abstract | Full Text

The detrimental effects of glucocorticoids exposure during pregnancy on offspring’s cardiac functions mediated by hypermethylation of bone morphogenetic protein-4

Jieying Peng, Yuhao Zhou, Zhiyu Zhang, Zhiming Wang, Lingtong Gao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0841-1

Abstract | Full Text

Knockdown of FOXA2 enhances the osteogenic differentiation of bone marrow-derived mesenchymal stem cells partly via activation of the ERK signalling pathway

Chenyi Ye, Mo Chen, Erman Chen, Weixu Li, Shengdong Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0857-6

Abstract | Full Text

Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis

Mariachiara Buccarelli, Matteo Marconi, Simone Pacioni, Ivana De Pasqualis, Quintino Giorgio D’Alessandris et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0864-7

Abstract | Full Text

Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts

De Li, Chenglong Wang, Zhuokai Li, Hui Wang, Jiye He et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0862-9

Abstract | Full Text

DBC1 regulates Wnt/β-catenin-mediated expression of MACC1, a key regulator of cancer progression, in colon cancer

Hwa Jin Kim, Sue Jin Moon, Seok-Hyung Kim, Kyu Heo & Jeong Hoon Kim

Cell Death & Disease 2018 9: 10.1038/s41419-018-0899-9

Abstract | Full Text

Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy

Wuzheng Zhu, Yujia Yuan, Guangneng Liao, Lan Li, Jingping Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0861-x

Abstract | Full Text

Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature

Tej Pratap Singh, Pablo A. Vieyra-Garcia, Karin Wagner, Josef Penninger & Peter Wolf

Cell Death & Disease 2018 9: 10.1038/s41419-018-0858-5

Abstract | Full Text

CiRS-7 promotes growth and metastasis of esophageal squamous cell carcinoma via regulation of miR-7/HOXB13

Rui-chao Li, Shun Ke, Fan-kai Meng, Jun Lu, Xiao-jing Zou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0852-y

Abstract | Full Text

Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer

Suhaib K. Abdeen, Uri Ben-David, Aya Shweiki, Bella Maly & Rami I. Aqeilan

Cell Death & Disease 2018 9: 10.1038/s41419-018-0896-z

Abstract | Full Text

Selective killing of human T-ALL cells: an integrated approach targeting redox homeostasis and the OMA1/OPA1 axis

Micol Silic-Benussi, Gloria Scattolin, Ilaria Cavallari, Sonia Minuzzo, Paola del Bianco et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0870-9

Abstract | Full Text

Double-edged sword of gonadotropin-releasing hormone (GnRH): A novel role of GnRH in the multiple beneficial functions of endometrial stem cells

Se-Ra Park, Ara Cho, Sung Taek Park, Chan Hum Park, Soyi Lim et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0892-3

Abstract | Full Text

Evaluating protective and therapeutic effects of alpha-lipoic acid on cisplatin-induced ototoxicity

Kyung-Hee Kim, Byeonghyeon Lee, Ye-Ri Kim, Min-A Kim, Nari Ryu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0888-z

Abstract | Full Text

Berberine ameliorates blockade of autophagic flux in the liver by regulating cholesterol metabolism and inhibiting COX2-prostaglandin synthesis

Haidong Sun, Qian Liu, Hai Hu, Yisheng Jiang, Wentao Shao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0890-5

Abstract | Full Text

Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1

Koyo Nishiyama, Reo Maruyama, Takeshi Niinuma, Masahiro Kai, Hiroshi Kitajima et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0893-2

Abstract | Full Text

Rsad2 is necessary for mouse dendritic cell maturation via the IRF7-mediated signaling pathway

Ji-Su Jang, Jun-Ho Lee, Nam-Chul Jung, So-Yeon Choi, Soo-Yeoun Park et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0889-y

Abstract | Full Text

PAK2–c-Myc–PKM2 axis plays an essential role in head and neck oncogenesis via regulating Warburg effect

Amit Gupta, Athira Ajith, Smriti Singh, Rajendra Kumar Panday, Atul Samaiya et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0887-0

Abstract | Full Text

Review Article

 

Prolyl isomerase Pin1: a promoter of cancer and a target for therapy

Yang Chen, Ya-ran Wu, Hong-ying Yang, Xin-zhe Li, Meng-meng Jie et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0844-y

Abstract | Full Text

Transdifferentiation: a new promise for neurodegenerative diseases

Cristiana Mollinari, Jian Zhao, Leonardo Lupacchini, Enrico Garaci, Daniela Merlo et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0891-4

Abstract | Full Text

Comment

 

How PERK kinase conveys stress signals to nuclear factor-κB to mediate estrogen-induced apoptosis in breast cancer cells?

Ping Fan & V. Craig Jordan

Cell Death & Disease 2018 9: 10.1038/s41419-018-0516-y

Abstract | Full Text

The antiproliferative and apoptotic profile of gomesin against DFTD

Maria P. Ikonomopoulou & Manuel A. Fernandez-Rojo

Cell Death & Disease 2018 9: 10.1038/s41419-018-0885-2

Abstract | Full Text

ApoNETosis: discovery of a novel form of neutrophil death with concomitant apoptosis and NETosis

Dhia Azzouz & Nades Palaniyar

Cell Death & Disease 2018 9: 10.1038/s41419-018-0846-9

Abstract | Full Text

Correction

 

Correction to: MicroRNA-125b reverses oxaliplatin resistance in hepatocellular carcinoma by negatively regulating EVA1A mediated autophagy

Wei-Wei Ren, Dan-Dan Li, Xiaolan Chen, Xiao-Long Li, Ya-Ping He et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0836-y

Abstract | Full Text

Correction to: Hsa-miR-623 suppresses tumor progression in human lung adenocarcinoma

Shuang Wei, Zun-yi Zhang, Sheng-ling Fu, Jun-gang Xie, Xian-sheng Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0880-7

Abstract | Full Text

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1 comment:

creative enzymes said...

Aldehyde dehydrogenase from yeast catalyzes the following reaction: RCHO + NAD/NADP+ + H2O → RCOOH + NADH/NADPH+ + H+. The yeast enzyme requires potassium ions and thiols (glutathione, 2-mercaptoethanol, cysteine) for its activity. aldehyde dehydrogenase