Nature Reviews Microbiology contents August 2018 Volume 16 Number 8

Advertisement Scientific Reports Top 100 in Ecology This collection presents the top 100 most highly accessed ecology articles published in Scientific Reports in 2017. Access the collection >>> TABLE OF CONTENTS August 2018 Volume 16, Issue 8 Research Highlights News & Analysis Reviews   Advertisement Nature Spotlight on Hong Kong: Building science innovation  Hong Kong is maximising major scientific innovation and commercial benefits through its proximity to the research and development hubs in mainland China. Yet barriers to collaboration remain. Access the full supplement for more    Advertisement Minimizing the Risk of Antimicrobial Resistance from Food Animal Production September 28, 2018, NYC This symposium will discuss the primary pathways of pathogen transmission, the drive to prioritize the use of non-medically important antibiotics and an array of strategies to mitigate antimicrobial resistance. Both in-person and via webinar. Register today.    Advertisement Nature Reviews Reader Survey At Nature Reviews we are continually looking for ways to ensure we meet our readers' needs. Your responses to this short survey will give us insight into how our content may be improved. Get started here.     Research Highlights   Gut microbiota bile acid metabolism controls cancer immunosurveillance    p453 Anna Dart doi:10.1038/s41579-018-0053-9 The gut microbiota can metabolize bile acids to affect immunosurveillance in the liver of mice and indirectly control the growth of primary liver tumours and liver metastases.   ppGpp triggers the switch    p454 Andrea Du Toit doi:10.1038/s41579-018-0042-z Breaking barriers    p454 Andrea Du Toit doi:10.1038/s41579-018-0043-y Four is a crowd    p454 Andrea Du Toit doi:10.1038/s41579-018-0044-x Sharing the burden to build a matrix    pp454 - 455 Ashley York doi:10.1038/s41579-018-0045-9 This study investigates the benefits of division of labour during extracellular matrix production within biofilms and show that both genetic and phenotypic strategies for a division of labour promote biofilm formation.   Falling into your own trap    pp454 - 455 Andrea Du Toit doi:10.1038/s41579-018-0054-8 Macrophage apoptosis induced by Staphylococcus aureus-generated deoxyadenosine involves a macrophage membrane transporter and kinases of the purine salvage pathway.   Oiling the Flavivirus replication machinery    p455 Ashley York doi:10.1038/s41579-018-0050-z New drugs underfoot?    p455 Ashley York doi:10.1038/s41579-018-0051-y An aquatic origin of retroviruses    p455 Ashley York doi:10.1038/s41579-018-0052-x Nature Reviews Microbiology JOBS of the week Postdoctoral Research Associate Texas A&M Institute of Biosciences and Technology Postdoctoral Positions at Stomatological Hospital of Guangzhou Medical University (SHGMU) Postdoctoral Positions at Stomatological Hospital of Guangzhou Medical University (SHGMU) Post Doctoral Research Scientist Rush University Medical Center (211-0571) Tenure-track Assistant Professor in Molecular Microbiology Department of Biology at the University of Copenhagen Research Associate x 2 posts Imperial College London More Science jobs from Nature Reviews Microbiology EVENT 3rd International Conference on Microbiology 14.12.18 Colombo, Sri Lanka More science events from News & Analysis   Surveying what’s flushed away    p456 Gregorio Iraola & Nitin Kumar doi:10.1038/s41579-018-0047-7 Advertisement Do you have a career question? The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud.  Listen today!   Reviews   Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier    pp457 - 470 Eric C. Martens, Mareike Neumann & Mahesh S. Desai doi:10.1038/s41579-018-0036-x The first line of host defence against both encroaching commensal bacteria and invading enteric pathogens is the intestinal mucosal barrier, which is composed of epithelial cells and a host-secreted mucous layer. In this Review, Martens and colleagues discuss the complex interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier.   Cyanobacterial blooms    pp471 - 483 Jef Huisman, Geoffrey A. Codd, Hans W. Paerl, Bas W. Ibelings, Jolanda M. H. Verspagen et al. doi:10.1038/s41579-018-0040-1 Cyanobacteria can form large blooms that threaten the water quality of lakes and seas. In this Review, Huisman and colleagues discuss bloom formation, the impact of eutrophication and climate change, and measures to prevent and control cyanobacterial blooms.   Going around in circles: virulence plasmids in enteric pathogens    pp484 - 495 Giulia Pilla & Christoph M. Tang doi:10.1038/s41579-018-0031-2 Virulence plasmids have a major role in the development of disease that is caused by enteric bacterial pathogens. In this Review, Pilla and Tang discuss virulence plasmids in enteric pathogens, outline the mechanisms by which they are maintained in bacterial populations and speculate on how these might contribute their propagation and success.   Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis    pp496 - 507 Sabine Ehrt, Dirk Schnappinger & Kyu Y. Rhee doi:10.1038/s41579-018-0013-4 As an obligate human pathogen, Mycobacterium tuberculosis has evolved to survive and thrive in biochemically challenging niches in its host. Ehrt, Schnappinger and Rhee review the unique metabolic features that enable M. tuberculosis pathogenesis and persistence but also represent drug targets.   Controlling vector-borne diseases by releasing modified mosquitoes    pp508 - 518 Heather A. Flores & Scott L. O’Neill doi:10.1038/s41579-018-0025-0 Flores and O’Neill review novel approaches to control mosquito-transmitted diseases, with a focus on control methods that are based on the release of mosquitoes, including the release of Wolbachia-infected mosquitoes, and strategies to genetically modify the vector.   Advertisement Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. 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