Advertisement | | NATURE FEATURE: Growing Pains for Gene Therapy Manufacturing The first of a four-part series highlighting new gene therapy production strategies and technologies. The first installment discusses the progress that has been made as the first wave of gene therapies win market approval and the challenges that must be overcome to relieve the production bottleneck when manufacturing cutting edge gene therapies at scale. Read feature here | | | | | | TABLE OF CONTENTS
| | | | Volume 25, Issue 3 | | In this issue Editorial Comment Review Article Article Brief Communication Also new AOP | Advertisement | | | | | | | | Advertisement | | The event will be led by scientists and clinicians researching, developing and testing new treatments for genetically inherited and acquired diseases, using gene delivery technology, stem cell manipulation and DNA repair techniques, covering aspects including: scientific principles, molecular basis of disease, current and developing technologies and clinical applications. More info | | | | | | | | | | Editorial | | | CAR-T in the clinic: drive with care Rafael J. Yáñez-Muñoz & Stephan A. Grupp Gene Therapy 2018 25 :157 - 161; July 01, 2018; 10.1038/s41434-018-0023-x Abstract | Full Text | | Comment | | | The revving up of CARs Muhammad Bilal Abid Gene Therapy 2018 25 :162 - 162; April 13, 2018; 10.1038/s41434-018-0015-x Abstract | Full Text | | | | | CAR-T: trailblazing the path from clinical development to the clinic Samuele Butera Gene Therapy 2018 25 :163 - 164; April 23, 2018; 10.1038/s41434-018-0013-z Abstract | Full Text | | | | | Driving cars to the clinic for solid tumors Mauro Castellarin, Keisuke Watanabe, Carl H. June, Christopher C. Kloss & Avery D. Posey Jr. Gene Therapy 2018 25 :165 - 175; June 07, 2018; 10.1038/s41434-018-0007-x Abstract | Full Text | | | | | Fludarabine and neurotoxicity in engineered T-cell therapy Kate L. Lowe, Crystal L. Mackall, Elliot Norry, Rafael Amado, Bent K. Jakobsen et al. Gene Therapy 2018 25 :176 - 191; May 07, 2018; 10.1038/s41434-018-0019-6 Abstract | Full Text | | Review Article | | | Interleukin-armed chimeric antigen receptor-modified T cells for cancer immunotherapy Y Huang, D Li, D-Y Qin, H-F Gou, W Wei et al. Gene Therapy 2017 25 :192 - 197; September 21, 2017; 10.1038/gt.2017.81 Abstract | Full Text | | Article | | | Excessive activated T-cell proliferation after anti-CD19 CAR T-cell therapy Wen-ying Zhang, Yang Liu, Yao Wang, Jing Nie, Ye-lei Guo et al. Gene Therapy 2018 25 :198 - 204; March 29, 2018; 10.1038/s41434-017-0001-8 Abstract | Full Text | | Brief Communication | | | Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain Jennifer A. Sullivan, Lisa M. Stanek, Michael J. Lukason, Jie Bu, Shayla R. Osmond et al. Gene Therapy 2018 25 :205 - 219; May 22, 2018; 10.1038/s41434-018-0017-8 Abstract | Full Text | | | | | In vivo selection with lentiviral expression of Bcl2T69A/S70A/S87A mutant in hematopoietic stem cell-transplanted mice Yan-Yi Wang, Shan Ma, Qingyong Chen, Demin Jiao & Yong Yang Gene Therapy 2018 25 :220 - 233; March 09, 2018; 10.1038/s41434-018-0008-9 Abstract | Full Text | | | | | Effects of microRNA-292-5p on myocardial ischemia–reperfusion injury through the peroxisome proliferator-activated receptor-α/-γ signaling pathway Zhen-Dong Zhu, Ji-Yun Ye, Hua Niu, Yu-Mei Ma, Xue-Mei Fu et al. Gene Therapy 2018 25 :234 - 248; April 18, 2018; 10.1038/s41434-018-0014-y Abstract | Full Text | | Advertisement | | Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. Click here to sign up. | | | | | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com | | | | | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to Gene Therapy. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Springer Nature |One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA Springer Nature's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW. © 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved. | | | |
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