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For more information visit the website. Visit our open access funding page or contact openaccess@nature.com to learn more about APC funding. | | | | Latest Comment | | | | | | | | Latest Articles | View all Articles | | | mTORC1 accelerates retinal development via the immunoproteasome OPEN | | Ji-Heon Choi, Hong Seok Jo, Soyeon Lim, Hyoung-Tai Kim, Kang Woo Lee, Kyeong Hwan Moon, Taejeong Ha, Sang Soo Kwak, Yeha Kim, Eun Jung Lee, Cheol O. Joe & Jin Woo Kim | | | One of the determinants of the neuronal subtype produced from retinal progenitor cells is their proliferative potential. Here the authors show that mTORC1 promotes progenitor cell cycle progression and hence accelerated development in mouse retina through induction of the immunoproteasome which enhances the degradation of cyclins. | | 27 June 2018 | doi: 10.1038/s41467-018-04774-9 | | Developmental neurogenesis Mitosis | Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome OPEN | | Yue Li, Michael E. Stockton, Brian E. Eisinger, Yinghua Zhao, Jessica L. Miller, Ismat Bhuiyan, Yu Gao, Zhiping Wu, Junmin Peng & Xinyu Zhao | | | Loss of fragile X mental retardation protein (FMRP) leads to fragile X syndrome, associated with cognitive dysfunction. Here the authors show that mice lacking FMRP show reduced hippocampal neurogenesis and cognitive deficits, which can be rescued by reducing histone acetylation. | | 27 June 2018 | doi: 10.1038/s41467-018-04869-3 | | Adult neurogenesis Autism spectrum disorders Neural stem cells | Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice OPEN | | I-Ling Lu, Chien Chen, Chien-Yi Tung, Hsin-Hung Chen, Jia-Ping Pan, Chia-Hsiang Chang, Jia-Shing Cheng, Yi-An Chen, Chun-Hung Wang, Chia-Wei Huang, Yi-Ning Kang, Hsin-Yun Chang, Lei-Li Li, Kai-Ping Chang, Yang-Hsin Shih, Chi-Hung Lin, Shang-Yeong Kwan & Jin-Wu Tsai | | | Cortical malformations have a variety of causes. Here the authors use transposon mutagenesis to insert mutations into neural stem cells in the developing mouse cortex to screen for new candidate genes for cortical malformation, and validate some targets in human brain tissue. | | 27 June 2018 | doi: 10.1038/s41467-018-04880-8 | | Developmental disorders Neuronal development | Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy OPEN | | Ali Talebi, Jonas Dehairs, Florian Rambow, Aljosja Rogiers, David Nittner, Rita Derua, Frank Vanderhoydonc, Joao A. G. Duarte, Francesca Bosisio, Kathleen Van den Eynde, Kris Nys, Mónica Vara Pérez, Patrizia Agostinis, Etienne Waelkens, Joost Van den Oord, Sarah-Maria Fendt, Jean-Christophe Marine & Johannes V. Swinnen | | | Melanoma patients harbouring BRAFV600E mutation generally develop resistance to targeted therapy. In this study, the authors demonstrate that SREBP-1-mediated induction of lipid biosynthesis contributes to therapy resistance in BRAF mutant melanoma. | | 27 June 2018 | doi: 10.1038/s41467-018-04664-0 | | Cancer metabolism Cancer therapeutic resistance Melanoma Phospholipids | Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods OPEN | | Michiel van de Waterbeemd, Sem Tamara, Kyle L. Fort, Eugen Damoc, Vojtech Franc, Philipp Bieri, Martin Itten, Alexander Makarov, Nenad Ban & Albert J. R. Heck | | | The authors demonstrate a 3-tier mass spectrometry approach, including bottom-up and top-down proteomics, as well as native mass spectrometry to provide a detailed description of proteoforms, protein processing and post-translational modifications present within ribosomes from bacteria, plant, and human. | | 27 June 2018 | doi: 10.1038/s41467-018-04853-x | | Proteomics Ribosomal proteins | Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations OPEN | | Joerg P. Burgstaller, Thomas Kolbe, Vitezslav Havlicek, Stephanie Hembach, Joanna Poulton, Jaroslav Piálek, Ralf Steinborn, Thomas Rülicke, Gottfried Brem, Nick S. Jones & Iain G. Johnston | | | Mitochondrial populations in cells may consist of heteroplasmic mixtures of mtDNA types, and their evolution through development, aging and generations is central to genetic diseases. Here the authors dissect these population dynamics using a large mouse-based data set to characterise the dynamics of heteroplasmy mean and variance throughout life and across generations. | | 27 June 2018 | doi: 10.1038/s41467-018-04797-2 | | Applied mathematics Mitochondria Mitochondrial genome Stochastic modelling | KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary OPEN | | R. Tyler Hillman, Joseph Celestino, Christopher Terranova, Hannah C. Beird, Curtis Gumbs, Latasha Little, Tri Nguyen, Rebecca Thornton, Samantha Tippen, Jianhua Zhang, Karen H. Lu, David M. Gershenson, Kunal Rai, Russell R. Broaddus & P. Andrew Futreal | | | Adult-type granulosa cell tumors of the ovary (aGCTs) are rare and recurrence is difficult to treat. Here, the authors observe in aGCT a novel recurrent somatic truncating mutation of KMT2D, more frequent in recurrent aGCT, and also non-genetic loss of KMT2D expression. | | 27 June 2018 | doi: 10.1038/s41467-018-04950-x | | Medical genomics Ovarian cancer | Nuclear Smad6 promotes gliomagenesis by negatively regulating PIAS3-mediated STAT3 inhibition OPEN | | Jiantong Jiao, Rui Zhang, Zheng Li, Ying Yin, Xiangming Fang, Xiaopeng Ding, Ying Cai, Shudong Yang, Huijun Mu, Da Zong, Yuexin Chen, Yansong Zhang, Jian Zou, Junfei Shao & Zhaohui Huang | | | In glioma STAT3 signaling contributes to gliomagenesis. Here, the authors show that Smad6 expression correlates with poor survival and is overexpressed in glioma cells, and regulates STAT3 activity via negatively regulating PIAS3. | | 27 June 2018 | doi: 10.1038/s41467-018-04936-9 | | Cancer prevention CNS cancer | Thermally-induced reversible structural isomerization in colloidal semiconductor CdS magic-size clusters OPEN | | Baowei Zhang, Tingting Zhu, Mingyang Ou, Nelson Rowell, Hongsong Fan, Jiantao Han, Lei Tan, Martin T. Dove, Yang Ren, Xiaobing Zuo, Shuo Han, Jianrong Zeng & Kui Yu | | | Few structural isomers of colloids, with identical masses but different structures, have been identified. Here, the authors observe an interesting example of structural isomerism in a pair of semiconductor magic-size clusters, which reversibly transform between one another with first-order unimolecular reaction kinetics. | | 27 June 2018 | doi: 10.1038/s41467-018-04842-0 | | Inorganic chemistry Quantum dots | Extremely strong polarization of an active asteroid (3200) Phaethon OPEN | | Takashi Ito, Masateru Ishiguro, Tomoko Arai, Masataka Imai, Tomohiko Sekiguchi, Yoonsoo P. Bach, Yuna G. Kwon, Masanori Kobayashi, Ryo Ishimaru, Hiroyuki Naito, Makoto Watanabe & Kiyoshi Kuramoto | | | (3200) Phaethon is a near-Earth asteroid discovered in 1983 that has large inclination and eccentricity. Here, the authors perform polarimetric observation of Phaethon over a wide range of solar phase angle and report that the asteroid exhibits a very strong linear polarization. | | 27 June 2018 | doi: 10.1038/s41467-018-04727-2 | | Asteroids, comets and Kuiper belt | Direct visualization of current-induced spin accumulation in topological insulators OPEN | | Yang Liu, Jean Besbas, Yi Wang, Pan He, Mengji Chen, Dapeng Zhu, Yang Wu, Jong Min Lee, Lan Wang, Jisoo Moon, Nikesh Koirala, Seongshik Oh & Hyunsoo Yang | | | Charge-to-spin conversion is a key theme of spintronics and its realization in topological materials is highly desired. Here, Liu et al. report spatial imaging of current-induced spin accumulation at the edges of Bi2Se3 and BiSbTeSe2 topological insulators. | | 27 June 2018 | doi: 10.1038/s41467-018-04939-6 | | Electronic devices Spintronics Topological insulators | Discovery of ZrCoBi based half Heuslers with high thermoelectric conversion efficiency OPEN | | Hangtian Zhu, Ran He, Jun Mao, Qing Zhu, Chunhua Li, Jifeng Sun, Wuyang Ren, Yumei Wang, Zihang Liu, Zhongjia Tang, Andrei Sotnikov, Zhiming Wang, David Broido, David J. Singh, Gang Chen, Kornelius Nielsch & Zhifeng Ren | | | Identifying new compounds with intrinsically high conversion efficiency is the key to demonstrating next-generation thermoelectric modules. Here, Zhu et al. report the discovery of p-type ZrCoBi-based half Heuslers with thermoelectric conversion efficiency of 9% and large high-temperature stability. | | 27 June 2018 | doi: 10.1038/s41467-018-04958-3 | | Synthesis and processing Thermoelectrics | A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion OPEN | | Sam J. B. Mallinson, Melodie M. Machovina, Rodrigo L. Silveira, Marc Garcia-Borràs, Nathan Gallup, Christopher W. Johnson, Mark D. Allen, Munir S. Skaf, Michael F. Crowley, Ellen L. Neidle, Kendall N. Houk, Gregg T. Beckham, Jennifer L. DuBois & John E. McGeehan | | | Catabolizing lignin-derived aromatic compounds requires an aryl-O-demethylation step. Here the authors present the structures of GcoA and GcoB, a cytochrome P450-reductase pair that catalyzes aryl-O-demethylations and show that GcoA displays broad substrate specificity, which is of interest for biotechnology applications. | | 27 June 2018 | doi: 10.1038/s41467-018-04878-2 | | Biophysical chemistry Enzyme mechanisms Enzymes Multienzyme complexes X-ray crystallography | Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1 OPEN | | Hamed Kooshapur, Nila Roy Choudhury, Bernd Simon, Max Mühlbauer, Alexander Jussupow, Noemi Fernandez, Alisha N. Jones, Andre Dallmann, Frank Gabel, Carlo Camilloni, Gracjan Michlewski, Javier F. Caceres & Michael Sattler | | | hnRNP A1 is an auxiliary factor that promotes the Microprocessor-mediated processing of pri-mir-18a, of the oncomiR-1 cluster. Here the authors employ an integrative structural biology approach and provide insights into the molecular mechanism of how hnRNP A1 facilitates pri-mir-18a biogenesis. | | 26 June 2018 | doi: 10.1038/s41467-018-04871-9 | | Proteins RNA SAXS Solution-state NMR Structural biology | Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction OPEN | | Serena Zacchigna, Valentina Martinelli, Silvia Moimas, Andrea Colliva, Marco Anzini, Andrea Nordio, Alessia Costa, Michael Rehman, Simone Vodret, Cristina Pierro, Giulia Colussi, Lorena Zentilin, Maria Ines Gutierrez, Ellen Dirkx, Carlin Long, Gianfranco Sinagra, David Klatzmann & Mauro Giacca | | | Regulatory T cells (Tregs) expand during pregnancy to promote tolerance towards the fetus. Here the authors show that Tregs induce proliferation of fetal and maternal cardiomyocytes during pregnancy and enhance myocardial repair via proliferation-promoting paracrine actions. | | 26 June 2018 | doi: 10.1038/s41467-018-04908-z | | Cardiac regeneration Cell division T cells | In utero nanoparticle delivery for site-specific genome editing OPEN | | Adele S. Ricciardi, Raman Bahal, James S. Farrelly, Elias Quijano, Anthony H. Bianchi, Valerie L. Luks, Rachael Putman, Francesc López-Giráldez, Süleyman Coşkun, Eric Song, Yanfeng Liu, Wei-Che Hsieh, Danith H. Ly, David H. Stitelman, Peter M. Glazer & W. Mark Saltzman | | | The correction of genetic defects in utero could allow for improved outcomes of gene therapy. Here, the authors demonstrate safe delivery of nanoparticles to fetal mouse tissues, and show that nanoparticles containing peptide nucleic acids to edit the beta-globin gene are effective in a mouse model of beta-thalassemia. | | 26 June 2018 | doi: 10.1038/s41467-018-04894-2 | | Genetic engineering Nanoparticles Peptide nucleic acid oligo Targeted gene repair | Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth OPEN | | Yuhan Chen, Qingyang Huang, Wen Liu, Qiong Zhu, Chun-Ping Cui, Liang Xu, Xing Guo, Ping Wang, Jingwen Liu, Guanglong Dong, Wenyi Wei, Cui Hua Liu, Zhichun Feng, Fuchu He & Lingqiang Zhang | | | Changes in glucose metabolism can lead to tumor development, but the involvement of splicing factors is unclear. Here, the authors screened for SR proteins and identified SRSF5 stability is enhanced in response to glucose elevation to promote alternative splicing of CCAR1 which facilitates tumor growth. | | 25 June 2018 | doi: 10.1038/s41467-018-04815-3 | | Acetylation RNA splicing Ubiquitylation | Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia OPEN | | Alexander Rosenberg, Iuliana V. Ene, Maayan Bibi, Shiri Zakin, Ella Shtifman Segal, Naomi Ziv, Alon M. Dahan, Arnaldo Lopes Colombo, Richard J. Bennett & Judith Berman | | | The authors show that antifungal tolerance, defined as the fraction of growth of a fungal pathogen above the minimal inhibitory concentration, is due to the slow growth of subpopulations of cells that overcome drug stress, and that high tolerance is often associated with persistent infections. | | 25 June 2018 | doi: 10.1038/s41467-018-04926-x | | Antifungal agents Cellular microbiology Fungal biology Pathogens Preclinical research | Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration OPEN | | Hannah Guak, Sara Al Habyan, Eric H. Ma, Haya Aldossary, Maia Al-Masri, So Yoon Won, Thomas Ying, Elizabeth D. Fixman, Russell G. Jones, Luke M. McCaffrey & Connie. M. Krawczyk | | | The activation of dendritic cells (DC) is associated with a metabolic switch from oxidative to glycolytic metabolism. Here, the authors show that both strong and weak stimuli cause an immediate increase in glycolysis, but only strong stimuli induce long-term glycolytic reprogramming. | | 25 June 2018 | doi: 10.1038/s41467-018-04804-6 | | Cell migration Dendritic cells Metabolomics | Accelerating the discovery of insensitive high-energy-density materials by a materials genome approach OPEN | | Yi Wang, Yuji Liu, Siwei Song, Zhijian Yang, Xiujuan Qi, Kangcai Wang, Yu Liu, Qinghua Zhang & Yong Tian | | | The synthesis of explosive materials that are stable, highly dense, and have low sensitivity to external stimuli is a challenge. Here, the authors use a genomic approach to accelerate the discovery of insensitive high explosive molecules with good detonation and low sensitivity properties. | | 22 June 2018 | doi: 10.1038/s41467-018-04897-z | | Computational chemistry Materials chemistry Organic chemistry | Systematic design of superaerophobic nanotube-array electrode comprised of transition-metal sulfides for overall water splitting OPEN | | Haoyi Li, Shuangming Chen, Ying Zhang, Qinghua Zhang, Xiaofan Jia, Qi Zhang, Lin Gu, Xiaoming Sun, Li Song & Xun Wang | | | Water splitting by nanostructured, abundant catalysts provides a renewable means to make carbon neutral fuels, but the ideal material morphology and composition remain uncertain. Here, the authors prepare superaerophobic, multi-metallic sulfide nanotube arrays as bifunctional water splitting catalysts. | | 22 June 2018 | doi: 10.1038/s41467-018-04888-0 | | Electrocatalysis Materials chemistry Synthesis and processing | Coupling of electrochemically triggered thermal and mechanical effects to aggravate failure in a layered cathode OPEN | | Pengfei Yan, Jianming Zheng, Tianwu Chen, Langli Luo, Yuyuan Jiang, Kuan Wang, Manling Sui, Ji-Guang Zhang, Sulin Zhang & Chongmin Wang | | | Electrochemical processes induce thermo-mechanical effects that mediate battery performance. Here the authors directly visualize cracking dynamics in a thermally perturbed, delithiated LiNi0.6Mn0.2Co0.2O2 cathode to demonstrate coupling between thermal, mechanical and electrochemical factors. | | 22 June 2018 | doi: 10.1038/s41467-018-04862-w | | Batteries | LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration OPEN | | Elvira Infante, Alessia Castagnino, Robin Ferrari, Pedro Monteiro, Sonia Agüera-González, Perrine Paul-Gilloteaux, Mélanie J. Domingues, Paolo Maiuri, Matthew Raab, Catherine M. Shanahan, Alexandre Baffet, Matthieu Piel, Edgar R. Gomes & Philippe Chavrier | | | The ability of cancer cells to migrate through small, constricted areas is limited by nuclear stiffness. Here the authors show that in turn nuclear stiffness stimulates the delivery of enzymes important for the degradation of the extracellular matrix and the formation of invadopodia in association with fibers thus opposing nuclear movement. | | 22 June 2018 | doi: 10.1038/s41467-018-04865-7 | | Cancer Invadopodia | Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory OPEN | | Samuel M. Cohen, Benjamin Suutari, Xingzhi He, Yang Wang, Sandrine Sanchez, Natasha N. Tirko, Nataniel J. Mandelberg, Caitlin Mullins, Guangjun Zhou, Shuqi Wang, Ilona Kats, Alejandro Salah, Richard W. Tsien & Huan Ma | | | Activity-dependent gene expression is thought to involve translocation of Ca2+/calmodulin (CaM) to the nucleus. Here, the authors examine a translocation-deficient mutant of γCaMKII, a Ca2+/CaM shuttle protein, to show that translocation of Ca2+/CaM is required for memory and synaptic plasticity. | | 22 June 2018 | doi: 10.1038/s41467-018-04705-8 | | Cellular neuroscience Molecular neuroscience | Precision therapeutic targeting of human cancer cell motility OPEN | | Li Xu, Ryan Gordon, Rebecca Farmer, Abhinandan Pattanayak, Andrew Binkowski, Xiaoke Huang, Michael Avram, Sankar Krishna, Eric Voll, Janet Pavese, Juan Chavez, James Bruce, Andrew Mazar, Antoinette Nibbs, Wayne Anderson, Lin Li, Borko Jovanovic, Sean Pruell, Matias Valsecchi, Giulio Francia et al. | | | In this study, the authors identify and validate a halogen-substituted isoflavanone able to inhibit prostate cancer cell motility, invasion and metastasis in vitro and in vivo. They demonstrate its ability to selectively inhibit activation of client proteins that stimulate cell motility. | | 22 June 2018 | doi: 10.1038/s41467-018-04465-5 | | Chemical tools Targeted therapies | TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons OPEN | | Layal Maatouk, Anne-Claire Compagnion, Maria-Angeles Carrillo-de Sauvage, Alexis-Pierre Bemelmans, Sabrina Leclere-Turbant, Vincent Cirotteau, Mira Tohme, Allen Beke, Michaël Trichet, Virginie Bazin, Bobby N. Trawick, Richard M. Ransohoff, François Tronche, Bénédicte Manoury & Sheela Vyas | | | Inflammation is a component of Parkinson’s disease. Here the authors show that activation of Toll-like receptor 9 controlled by microglial glucocorticoid receptor signaling, contributes to dopamine neuron loss in a model of Parkinson’s disease. | | 22 June 2018 | doi: 10.1038/s41467-018-04569-y | | Neuroimmunology Parkinson's disease | Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors OPEN | | César López-Camacho, Peter Abbink, Rafael A. Larocca, Wanwisa Dejnirattisai, Michael Boyd, Alex Badamchi-Zadeh, Zoë R. Wallace, Jennifer Doig, Ricardo Sanchez Velazquez, Roberto Dias Lins Neto, Danilo F. Coelho, Young Chan Kim, Claire L. Donald, Ania Owsianka, Giuditta De Lorenzo, Alain Kohl, Sarah C. Gilbert, Lucy Dorrell, Juthathip Mongkolsapaya, Arvind H. Patel et al. | | | Zika virus (ZIKV) is an emerging global health issue, but currently no licensed vaccine achieves lasting protective immunity. Here the authors show that a ZIKV vaccine containing the envelop protein without the transmembrane domain and the precursor membrane protein can provide effective protection in mouse models. | | 22 June 2018 | doi: 10.1038/s41467-018-04859-5 | | Molecular medicine Vaccines Viral infection | Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL OPEN | | Shuiming Qian, Xinchen Lv, Ray N. Scheid, Li Lu, Zhenlin Yang, Wei Chen, Rui Liu, Melissa D. Boersma, John M. Denu, Xuehua Zhong & Jiamu Du | | | Histone mark reader proteins bind to particular histone modifications and regulate chromatin state. Here, Qian et al. show that the SHORT LIFE reader has a unique ability to recognize both activating and repressive histone marks and that these interactions enable SHORT LIFE to repress flowering in plants. | | 21 June 2018 | doi: 10.1038/s41467-018-04836-y | | Epigenetics Plant molecular biology X-ray crystallography | IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes OPEN | | Yukihide Momozawa, Julia Dmitrieva, Emilie Théâtre, Valérie Deffontaine, Souad Rahmouni, Benoît Charloteaux, François Crins, Elisa Docampo, Mahmoud Elansary, Ann-Stephan Gori, Christelle Lecut, Rob Mariman, Myriam Mni, Cécile Oury, Ilya Altukhov, Dmitry Alexeev, Yuri Aulchenko, Leila Amininejad, Gerd Bouma, Frank Hoentjen et al. | | | Most of the more than 200 known genetic risk loci for inflammatory bowel disease (IBD) reside in regulatory regions. Here, the authors provide eQTL datasets for six circulating immune cell types and ileal, colonic and rectal biopsies to map regulatory modules and identify potential causative genes for IBD. | | 21 June 2018 | doi: 10.1038/s41467-018-04365-8 | | Genetics research Genome-wide association studies Immunogenetics Inflammatory bowel disease | Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis OPEN | | Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Wardak, Lung-Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessene, John Silke, Peter E. Czabotar, Andrew I. Webb & James M. Murphy | | | RIPK3-mediated phosphorylation of the mixed lineage kinase domain-like (MLKL) pseudokinase is thought to be the trigger for MLKL activation during necroptotic signaling. Here the authors provide evidence that the transition of human MLKL from a monomeric state to a tetramer is essential for necroptosis signalling. | | 21 June 2018 | doi: 10.1038/s41467-018-04714-7 | | Kinases Mass spectrometry Necroptosis SAXS | | | | | | | | Latest Author Correction | | | | | | | | Advertisement | | | | | Advertisement | | Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours. Click here to sign up. | | | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. 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