The Pharmacogenomics Journal - Table of Contents alert Volume 18 Issue 3

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TABLE OF CONTENTS Volume 18, Issue 3 (May 2018) In this issue Review Original Articles Also new AOP   Sign up for e-alerts Recommend to your library Web feed Subscribe   Review Top Harnessing low-density lipoprotein receptor protein 6 (LRP6) genetic variation and Wnt signaling for innovative diagnostics in complex diseases OPEN Z-M Wang, J-Q Luo, L-Y Xu, H-H Zhou and W Zhang Pharmacogenomics J 2018 18: 351-358; advance online publication, July 11, 2017; 10.1038/tpj.2017.28 Abstract | Full Text Original Articles Top Applications of pharmacogenomics in regulatory science: a product life cycle review W C Tan-Koi, P C Leow and Y Y Teo Pharmacogenomics J 2018 18: 359-366; advance online publication, December 5, 2017; 10.1038/tpj.2017.47 Abstract | Full Text Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest D J Pappas, A Lizee, V Paunic, K R Beutner, A Motyer, D Vukcevic, S Leslie, J Biesiada, J Meller, K D Taylor, X Zheng, L P Zhao, P-A Gourraud, J A Hollenbach, S J Mack and M Maiers Pharmacogenomics J 2018 18: 367-376; advance online publication, April 25, 2017; 10.1038/tpj.2017.7 Abstract | Full Text Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity OPEN J J Sutherland, Y W Webster, J A Willy, G H Searfoss, K M Goldstein, A R Irizarry, D G Hall and J L Stevens Pharmacogenomics J 2018 18: 377-390; advance online publication, April 25, 2017; 10.1038/tpj.2017.17 Abstract | Full Text A cost-effectiveness analysis of maternal CYP2D6 genetic testing to guide treatment for postpartum pain and avert infant adverse events M E Moretti, D F Lato, H Berger, G Koren, S Ito and W J Ungar Pharmacogenomics J 2018 18: 391-397; advance online publication, July 11, 2017; 10.1038/tpj.2017.33 Abstract | Full Text Genome-wide meta-analysis of copy number variations with alcohol dependence A Sulovari, Z Liu, Z Zhu and D Li Pharmacogenomics J 2018 18: 398-405; advance online publication, July 11, 2017; 10.1038/tpj.2017.35 Abstract | Full Text Genome-wide association studies of placebo and duloxetine response in major depressive disorder M Maciukiewicz, V S Marshe, A K Tiwari, T M Fonseka, N Freeman, J L Kennedy, S Rotzinger, J A Foster, S H Kennedy and D J Müller Pharmacogenomics J 2018 18: 406-412; advance online publication, July 11, 2017; 10.1038/tpj.2017.29 Abstract | Full Text New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation C Fabbri, K E Tansey, R H Perlis, J Hauser, N Henigsberg, W Maier, O Mors, A Placentino, M Rietschel, D Souery, G Breen, C Curtis, L Sang-Hyuk, S Newhouse, H Patel, M Guipponi, N Perroud, G Bondolfi, M O'Donovan, G Lewis, J M Biernacka, R M Weinshilboum, A Farmer, K J Aitchison, I Craig, P McGuffin, R Uher and C M Lewis Pharmacogenomics J 2018 18: 413-421; advance online publication, November 21, 2017; 10.1038/tpj.2017.44 Abstract | Full Text The predictive value of ABCB1, ABCG2, CYP3A4/5 and CYP2D6 polymorphisms for risperidone and aripiprazole plasma concentrations and the occurrence of adverse drug reactions C Rafaniello, M Sessa, F F Bernardi, M Pozzi, S Cheli, D Cattaneo, S Baldelli, M Molteni, R Bernardini, F Rossi, E Clementi, C Bravaccio, S Radice and A Capuano Pharmacogenomics J 2018 18: 422-430; advance online publication, July 18, 2017; 10.1038/tpj.2017.38 Abstract | Full Text Pharmacogenetics of oral antidiabetes drugs: evidence for diverse signals at the IRS1 locus S Prudente, R Di Paola, S Pezzilli, M Garofolo, O Lamacchia, T Filardi, G C Mannino, L Mercuri, F Alberico, M G Scarale, G Sesti, S Morano, G Penno, M Cignarelli, M Copetti and V Trischitta Pharmacogenomics J 2018 18: 431-435; advance online publication, July 11, 2017; 10.1038/tpj.2017.32 Abstract | Full Text Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates OPEN D I Staquicini, S D'Angelo, F Ferrara, K Karjalainen, G Sharma, T L Smith, C A Tarleton, D E Jaalouk, A Kuniyasu, W B Baze, B K Chaffee, P W Hanley, K F Barnhart, E Koivunen, S Marchiò, R L Sidman, J E Cortes, H M Kantarjian, W Arap and R Pasqualini Pharmacogenomics J 2018 18: 436-443; advance online publication, December 5, 2017; 10.1038/tpj.2017.46 Abstract | Full Text MTHFR, TS and XRCC1 genetic variants may affect survival in patients with myelodysplastic syndromes treated with supportive care or azacitidine OPEN G Visani, F Loscocco, A Ruzzo, S Galimberti, F Graziano, M T Voso, E Giacomini, C Finelli, E Ciabatti, E Fabiani, S Barulli, A Volpe, D Magro, P Piccaluga, F Fuligni, M Vignetti, P Fazi, A Piciocchi, E Gabucci, M Rocchi, M Magnani and A Isidori Pharmacogenomics J 2018 18: 444-449; advance online publication, December 5, 2017; 10.1038/tpj.2017.48 Abstract | Full Text Associations between the C677T and A1298C polymorphisms of MTHFR and the toxicity of methotrexate in childhood malignancies: a meta-analysis C Zhu, Y W Liu, S Z Wang, X L Li, X L Nie, X T Yu, L B Zhao and X L Wang Pharmacogenomics J 2018 18: 450-459; advance online publication, July 11, 2017; 10.1038/tpj.2017.34 Abstract | Full Text Imatinib-induced ophthalmological side-effects in GIST patients are associated with the variations of EGFR, SLC22A1, SLC22A5 and ABCB1 OPEN H-B Qiu, W Zhuang, T Wu, S Xin, C-Z Lin, H-L Ruan, X Zhu, M Huang, J-L Li, X-Y Hou, Z-W Zhou and X-D Wang Pharmacogenomics J 2018 18: 460-466; advance online publication, August 1, 2017; 10.1038/tpj.2017.40 Abstract | Full Text Gene expression and linkage analysis implicate CBLB as a mediator of rituximab resistance J Jack, G W Small, C C Brown, T M Havener, H L McLeod, A A Motsinger-Reif and K L Richards Pharmacogenomics J 2018 18: 467-473; advance online publication, December 5, 2017; 10.1038/tpj.2017.41 Abstract | Full Text The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab T Magnes, T Melchardt, C Hufnagl, L Weiss, C Mittermair, D Neureiter, E Klieser, G Rinnerthaler, S Roesch, A Gaggl, R Greil and A Egle Pharmacogenomics J 2018 18: 474-479; advance online publication, July 18, 2017; 10.1038/tpj.2017.37 Abstract | Full Text Characterisation of the HLA-DRB1*07:01 biomarker for lapatinib-induced liver toxicity during treatment of early-stage breast cancer patients with lapatinib in combination with trastuzumab and/or taxanes C F Spraggs, L R Parham, L P Briley, L Warren, L S Williams, D J Fraser, Z Jiang, Z Aziz, S Ahmed, G Demetriou, A Mehta, N Jackson, J Byrne, M Andersson, M Toi, L Harris, J Gralow, J A Zujewski, R Crescenzo, A Armour, E Perez and M Piccart Pharmacogenomics J 2018 18: 480-486; advance online publication, August 8, 2017; 10.1038/tpj.2017.39 Abstract | Full Text The PNPLA3 I148M variant is associated with transaminase elevations in type 2 diabetes patients treated with basal insulin peglispro S Pillai, S Duvvuru, P Bhatnagar, W Foster, M Farmen, S Shankar, C Harris, E Bastyr, III, B Hoogwerf and A Haupt Pharmacogenomics J 2018 18: 487-493; advance online publication, November 21, 2017; 10.1038/tpj.2017.45 Abstract | Full Text Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis OPEN N D Loft, L Skov, L Iversen, R Gniadecki, T N Dam, I Brandslund, H J Hoffmann, M R Andersen, R B Dessau, A C Bergmann, N M Andersen, P S Andersen, S Bank, U Vogel and V Andersen Pharmacogenomics J 2018 18: 494-500; advance online publication, July 11, 2017; 10.1038/tpj.2017.31 Abstract | Full Text Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients W S Oetting, B Wu, D P Schladt, W Guan, R P Remmel, R B Mannon, A J Matas, A K Israni and P A Jacobson for the DeKAF Genomics Investigators Pharmacogenomics J 2018 18: 501-505; advance online publication, November 21, 2017; 10.1038/tpj.2017.49 Abstract | Full Text Role of CYP24A1, VDR and GC gene polymorphisms on deferasirox pharmacokinetics and clinical outcomes S Allegra, J Cusato, S De Francia, A Arduino, F Longo, E Pirro, D Massano, A De Nicolò, A Piga and A D'Avolio Pharmacogenomics J 2018 18: 506-515; advance online publication, November 21, 2017; 10.1038/tpj.2017.43 Abstract | Full Text   Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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