The EMBO Journal Table of Contents for 02 May 2018; Vol. 37, No. 9

02 May 2018 | Volume 37, Number 9 Submit Table of Contents News & Views Articles Volume 37, Number 9 News & Views Past stem cells and finally in transit: SLC1A3 instructs skin niche coupling Recent work shows coordinated growth of three distinct epithelial niches and a functional role for glutamate transporter SLC1A3 in activation of stem and progenitor cells. Edwige Roy and Kiarash Khosrotehrani Published online 18.04.2018 Pushed out of a tough crowd: centrosome aberrations promote invasiveness Non‐cell‐autonomous budding of mitotic cells from an epithelium suggests how structural centrosome alterations might cause dissemination of metastatic cells. Lauren T Evans and Andrew J Holland Published online 05.04.2018 Articles Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth Stem and progenitor cell proliferation is synchronized over distinct compartments in the skin and controlled by SLC1A3 during postnatal epidermal development. Bettina Reichenbach, Johanna Classon, Tomomi Aida, Kohichi Tanaka, Maria Genander and Christian Göritz Published online 03.04.2018 Structural centrosome aberrations promote non‐cell‐autonomous invasiveness Decreased adherence and increased stiffness of cells overexpressing centrosomal ninein‐like protein causes dissemination of wild‐type cells undergoing mitosis from mosaic epithelia. Olivier Ganier, Dominik Schnerch, Philipp Oertle, Roderick YH Lim, Marija Plodinec and Erich A Nigg Published online 22.03.2018 Synaptic activity‐induced glycolysis facilitates membrane lipid provision and neurite outgrowth Neuronal membrane expansion required for neurite outgrowth upon synaptic stimulation involves concomitant upregulation of glucose uptake and metabolism, supporting lipid biosynthesis. Marc Segarra‐Mondejar, Sergi Casellas‐Díaz, Marina Ramiro‐Pareta, Claudia Müller‐Sánchez, Alejandro Martorell‐Riera, Ismaïl Hermelo, Manuel Reina, Julián Aragonés, Ofelia M Martínez‐Estrada and Francesc X Soriano Published online 03.04.2018 Spatial separation between replisome‐ and template‐induced replication stress signaling Checkpoint activation upon replication‐blocking lesions originates from Exo1‐processed daughter‐strand gaps and Rad9 signaling, distinguishing it from Mrc1‐dependent responses to replisome‐inherent problems. Néstor García‐Rodríguez, Magdalena Morawska, Ronald P Wong, Yasukazu Daigaku and Helle D Ulrich Published online 26.03.2018 Contact‐dependent growth inhibition induces high levels of antibiotic‐tolerant persister cells in clonal bacterial populations Contact‐mediated stringent response activation provides an alternative bet‐hedging strategy for antibiotic tolerance at high cell‐densities. Anirban Ghosh, Özden Baltekin, Marcus Wäneskog, Dina Elkhalifa, Disa L Hammarlöf, Johan Elf and Sanna Koskiniemi Published online 23.03.2018 Phospholipid‐flipping activity of P4‐ATPase drives membrane curvature Phosphatidylcholine‐flipping at the plasma membrane can induce inward membrane curvature and membrane tubule formation upon recruitment of BAR domains to the plasma membrane. Naoto Takada, Tomoki Naito, Takanari Inoue, Kazuhisa Nakayama, Hiroyuki Takatsu and Hye‐Won Shin Published online 29.03.2018 PTRN‐1/CAMSAP promotes CYK‐1/formin‐dependent actin polymerization during endocytic recycling Direct interaction of the actin regulator formin with a patronin/CAMSAP‐family microtubule‐binding protein in C. elegans reveals an unexpected role of patronin in actin cytoskeleton remodeling during vesicle transport. Ting Gong, Yanling Yan, Jing Zhang, Shuai Liu, Hang Liu, Jinghu Gao, Xin Zhou, Juan Chen and Anbing Shi Published online 22.03.2018 Endosome maturation factors Rabenosyn‐5/VPS45 and caveolin‐1 regulate ciliary membrane and polycystin‐2 homeostasis Endosomal uptake and sorting affect male mating behaviour in Caenorhabditis elegans by regulating ciliary membrane dynamics and the localization of polycystic kidney disease‐associated factor polycystin‐2 in sensory cilia. Noémie Scheidel, Julie Kennedy and Oliver E Blacque Published online 23.03.2018   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2017 by the European Molecular Biology Organisation.