Wednesday, April 4, 2018

Leukemia - Table of Contents alert Volume 32 Issue 4

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Leukemia
 
TABLE OF CONTENTS

Volume 32, Issue 4 (April 2018)

In this issue
Original Articles
Letters to the Editor
Correspondence
Corrigendum
Also new
AOP
 

Original Articles

Acute myeloid leukemia

Dual inhibition of EZH1/2 breaks the quiescence of leukemia stem cells in acute myeloid leukemia

S Fujita, D Honma, N Adachi, K Araki, E Takamatsu et al.

Leukemia 2017 32 :855 - 864; September 27, 2017; 10.1038/leu.2017.300

 

Abstract | Full Text

A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target

F Yan, N Shen, J X Pang, N Zhao, Y W Zhang et al.

Leukemia 2017 32 :865 - 873; October 10, 2017; 10.1038/leu.2017.307

 

Abstract | Full Text

Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia

L Lhermitte, E Mejstrikova, A J van der Sluijs-Gelling, G E Grigore, L Sedek et al.

Leukemia 2017 32 :874 - 881; November 01, 2017; 10.1038/leu.2017.313

 

Abstract | Full Text

Targeting acute myeloid leukemia by drug-induced c-MYB degradation

V Walf-Vorderwülbecke, K Pearce, T Brooks, M Hubank, M M van den Heuvel-Eibrink et al.

Leukemia 2017 32 :882 - 889; November 01, 2017; 10.1038/leu.2017.317

 

Abstract | Full Text

SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia

J Bu, A Chen, X Yan, F He, Y Dong et al.

Leukemia 2017 32 :890 - 899; November 29, 2017; 10.1038/leu.2017.339

 

Abstract | Full Text

AZA-MS: a novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo

A Unnikrishnan, A N Q Vo, R Pickford, M J Raftery, A C Nunez et al.

Leukemia 2017 32 :900 - 910; November 29, 2017; 10.1038/leu.2017.340

 

Abstract | Full Text

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia

A G Sanarico, C Ronchini, A Croce, E M Memmi, U A Cammarata et al.

Leukemia 2017 32 :911 - 919; December 06, 2017; 10.1038/leu.2017.342

 

Abstract | Full Text

Molecular targets for therapy

Pharmacodynamics and proteomic analysis of acalabrutinib therapy: similarity of on-target effects to ibrutinib and rationale for combination therapy

V K Patel, B Lamothe, M L Ayres, J Gay, J P Cheung et al.

Leukemia 2017 32 :920 - 930; November 03, 2017; 10.1038/leu.2017.321

 

Abstract | Full Text

Acute lymphoblastic leukemia

RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia

I S Jerchel, A Q Hoogkamer, I M Ariës, E M P Steeghs, J M Boer et al.

Leukemia 2017 32 :931 - 940; October 03, 2017; 10.1038/leu.2017.303

 

Abstract | Full Text

Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system

S Bornschein, S Demeyer, R Stirparo, O Gielen, C Vicente et al.

Leukemia 2017 32 :941 - 951; November 20, 2017; 10.1038/leu.2017.328

 

Abstract | Full Text

Chronic myelogenous leukemia

Risk of developing chronic myeloid neoplasms in well-differentiated thyroid cancer patients treated with radioactive iodine

R J Molenaar, C Pleyer, T Radivoyevitch, S Sidana, A Godley et al.

Leukemia 2017 32 :952 - 959; November 06, 2017; 10.1038/leu.2017.323

 

Abstract | Full Text

Chronic lymphocytic leukemia

Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway

K Kondo, H Shaim, P A Thompson, J A Burger, M Keating et al.

Leukemia 2017 32 :960 - 970; October 03, 2017; 10.1038/leu.2017.304

 

Abstract | Full Text

Multiple myeloma, gammopathies

Prognostic value of antigen expression in multiple myeloma: a PETHEMA/GEM study on 1265 patients enrolled in four consecutive clinical trials

P Arana, B Paiva, M-T Cedena, N Puig, L Cordon et al.

Leukemia 2017 32 :971 - 978; November 03, 2017; 10.1038/leu.2017.320

 

Abstract | Full Text

Phase 1/2 study of weekly carfilzomib, cyclophosphamide, dexamethasone in newly diagnosed transplant-ineligible myeloma

S Bringhen, M D'Agostino, L De Paoli, V Montefusco, A M Liberati et al.

Leukemia 2017 32 :979 - 985; November 16, 2017; 10.1038/leu.2017.327

 

Abstract | Full Text

Early relapse after autologous hematopoietic cell transplantation remains a poor prognostic factor in multiple myeloma but outcomes have improved over time

S K Kumar, A Dispenzieri, R Fraser, F Mingwei, G Akpek et al.

Leukemia 2017 32 :986 - 995; November 16, 2017; 10.1038/leu.2017.331

 

Abstract | Full Text

Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma

A Gullà, T Hideshima, G Bianchi, M Fulciniti, M Kemal Samur et al.

Leukemia 2017 32 :996 - 1002; November 21, 2017; 10.1038/leu.2017.334

 

Abstract | Full Text

MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells

C Botta, M Cucè, M R Pitari, D Caracciolo, A Gullà et al.

Leukemia 2017 32 :1003 - 1015; November 21, 2017; 10.1038/leu.2017.336

 

Abstract | Full Text

Chronic myeloproliferative neoplasms

Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells

B Peter, S Bibi, G Eisenwort, B Wingelhofer, D Berger et al.

Leukemia 2017 32 :1016 - 1022; November 29, 2017; 10.1038/leu.2017.338

 

Abstract | Full Text

Stem cell biology

Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS

Y Mei, B Zhao, A A Basiorka, J Yang, L Cao et al.

Leukemia 2017 32 :1023 - 1033; November 16, 2017; 10.1038/leu.2017.326

 

Abstract | Full Text

Letters to the Editor

Long-term efficacy and safety of momelotinib, a JAK1 and JAK2 inhibitor, for the treatment of myelofibrosis

A Pardanani, J Gotlib, A W Roberts, M Wadleigh, S Sirhan et al.

Leukemia 2017 32 :1034 - 1037; November 16, 2017; 10.1038/leu.2017.330

 

Abstract | Full Text

Towards ‘off-the-shelf’ genetically modified T cells: prolonging functional engraftment in mice by CD8 veto T cells

N Or-Geva, R Gidron-Budovsky, L Radomir, Y Edelstein, A K Singh et al.

Leukemia 2017 32 :1038 - 1040; November 20, 2017; 10.1038/leu.2017.332

 

Abstract | Full Text

Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity

S Marsilio, H Khiabanian, G Fabbri, S Vergani, C Scuoppo et al.

Leukemia 2017 32 :1040 - 1043; December 05, 2017; 10.1038/leu.2017.343

 

Abstract | Full Text

Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines

F Maura, M Petljak, M Lionetti, I Cifola, W Liang et al.

Leukemia 2017 32 :1043 - 1047; December 06, 2017; 10.1038/leu.2017.345

 

Abstract | Full Text

CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

I Tirado-Gonzalez, E Czlonka, A Nevmerzhitskaya, D Soetopo, E Bergonzani et al.

Leukemia 2017 32 :1048 - 1051; December 06, 2017; 10.1038/leu.2017.346

 

Abstract | Full Text

Correspondence

The role of bone marrow morphology in the diagnosis of relapsed acute myeloid leukemia

B Said, S Gilles, D Weisdorf & A Rashidi

Leukemia 2017 32 :1052 - 1052; October 31, 2017; 10.1038/leu.2017.308

 

Abstract | Full Text

Corrigendum

Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML

C Schütz, S Inselmann, S Saussele, C T Dietz, M C Müller et al.

Leukemia 2018 32 :1053 - 1053; January 30, 2018; 10.1038/leu.2017.348

 

Abstract | Full Text

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