The EMBO Journal Table of Contents for 15 March 2018; Vol. 37, No. 6

15 March 2018 | Volume 37, Number 6 Submit Table of Contents News & Views Resource Articles Corrigendum Volume 37, Number 6 News & Views No way out: when RNA elements promote nuclear retention High‐throughput RNA oligo tiling provides a new method for testing functional domains in long noncoding RNAs, shedding light on this diverse and poorly understood group of transcripts. Federico Agostini, Jernej Ule and Julian A Zagalak Published online 27.02.2018 Resource High‐throughput identification of RNA nuclear enrichment sequences A new tiling‐based method maps functional domains across a panel of long non‐coding RNAs, identifying sequence motifs that retain these RNAs in the nucleus. Chinmay J Shukla, Alexandra L McCorkindale, Chiara Gerhardinger, Keegan D Korthauer, Moran N Cabili, David M Shechner, Rafael A Irizarry, Philipp G Maass and John L Rinn Published online 15.01.2018 Articles LPS targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation Immunogenicity of bacterial outer membrane vesicles is linked to lipopolysaccharide delivery and TLR4‐TRIF signaling in host macrophages. José Carlos Santos, Mathias S Dick, Brice Lagrange, Daniel Degrandi, Klaus Pfeffer, Masahiro Yamamoto, Etienne Meunier, Pawel Pelczar, Thomas Henry and Petr Broz Published online 19.02.2018 Prion‐like protein aggregates exploit the RHO GTPase to cofilin‐1 signaling pathway to enter cells RNAi screening shows that pathological protein aggregates harness a signaling pathway also utilized by viruses to remodel cortical actin and invade host cells. Zhen Zhong, Laura Grasso, Caroline Sibilla, Tim J Stevens, Nicholas Barry and Anne Bertolotti Published online 01.03.2018 Molecular basis for sterol transport by StART‐like lipid transfer domains Mammalian LAM family proteins have StART‐like lipid transfer domains, transferring sterols efficiently. The structure of the lipid transfer module of a yeast LAM protein reveals how StART proteins bind sterol. Florian A Horenkamp, Diana P Valverde, Jodi Nunnari and Karin M Reinisch Published online 21.02.2018 A single nucleotide incorporation step limits human telomerase repeat addition activity A template‐encoded pause‐signal links processive repeat addition of human telomerase to cellular nucleotide levels. Yinnan Chen, Joshua D Podlevsky, Dhenugen Logeswaran and Julian J‐L Chen Published online 12.02.2018 Structural basis of siRNA recognition by TRBP double‐stranded RNA binding domains NMR studies of the dsRNA‐binding protein TRBP suggest that its role in facilitating miRNA biogenesis is to increase accuracy of the Dicer RNase. Gregoire Masliah, Christophe Maris, Sebastian LB König, Maxim Yulikov, Florian Aeschimann, Anna L Malinowska, Julie Mabille, Jan Weiler, Andrea Holla, Juerg Hunziker, Nicole Meisner‐Kober, Benjamin Schuler, Gunnar Jeschke and Frederic H‐T Allain Published online 15.02.2018 HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry Tethering experiments and detection of H3S10 phosphorylation in G2 suggest that HP1 initially clusters the chromosomal passenger complex for activation, before other epigenetic marks determine its cent localisation in mitosis. Jan G Ruppert, Kumiko Samejima, Melpomeni Platani, Oscar Molina, Hiroshi Kimura, A Arockia Jeyaprakash, Shinya Ohta and William C Earnshaw Published online 21.02.2018 Corrigendum The pseudophosphatase STYX targets the F‐box of FBXW7 and inhibits SCFFBXW7 function Veronika Reiterer, Cristina Figueras‐Puig, Francois Le Guerroue, Stefano Confalonieri, Manuela Vecchi, Dasaradha Jalapothu, Sandip M Kanse, Raymond J Deshaies, Pier Paolo Di Fiore, Christian Behrends and Hesso Farhan Published online 15.03.2018   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 973 University Avenue * Los Gatos, CA 95032 * U.S.A. Copyright © 2017 by the European Molecular Biology Organisation.