Thursday, February 22, 2018

Oncogene - Table of Contents alert Volume 37 Issue 8

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The new SRG rat™, is a Sprague-Dawley SCID rat with knockouts in the Rag2 and Il2rg genes. The SRG rat lacks B-cells, T-cells, and NK-cells and enables tumor model studies that are inefficient or not feasible in mouse.

For example, the VCaP prostate model demonstrates a high tumor take rate (> 70%) in SRG rats. Efficiency gains and larger sample sizes save time and money. Can the SRG rat enable your oncology research? See the data & learn more. 

Volume 37, Issue 8 (February 2018)

In this issue
Original Articles
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Transcribing malignancy: transcription-associated genomic instability in cancer

B Boulianne & N Feldhahn

Oncogene 2017 37 :971 - 981; November 06, 2017; 10.1038/onc.2017.402


Abstract | Full Text

Original Articles

Calcium signalling links MYC to NUAK1

T Monteverde, J Tait-Mulder, A Hedley, J R Knight, O J Sansom et al.

Oncogene 2017 37 :982 - 992; November 06, 2017; 10.1038/onc.2017.394


Abstract | Full Text

Aberrant GATA2 epigenetic dysregulation induces a GATA2/GATA6 switch in human gastric cancer

S H Song, M S Jeon, J W Nam, J K Kang, Y J Lee et al.

Oncogene 2017 37 :993 - 1004; November 06, 2017; 10.1038/onc.2017.397


Abstract | Full Text

ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells

E M Langer, N D Kendsersky, C J Daniel, G M Kuziel, C Pelz et al.

Oncogene 2017 37 :1005 - 1019; October 30, 2017; 10.1038/onc.2017.356


Abstract | Full Text

Transcription factor c-Myb inhibits breast cancer lung metastasis by suppression of tumor cell seeding

L Knopfová, E Biglieri, N Volodko, M Masařík, M Hermanová et al.

Oncogene 2017 37 :1020 - 1030; October 30, 2017; 10.1038/onc.2017.392


Abstract | Full Text

MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells

A L Schroyer, N W Stimes, W F Abi Saab & D N Chadee

Oncogene 2017 37 :1031 - 1040; October 30, 2017; 10.1038/onc.2017.396


Abstract | Full Text

Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth

D Ma, X Chen, P-Y Zhang, H Zhang, L-J Wei et al.

Oncogene 2017 37 :1041 - 1048; October 30, 2017; 10.1038/onc.2017.398


Abstract | Full Text

SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex

S-J Zhao, Y-Q Jiang, N-W Xu, Q Li, Q Zhang et al.

Oncogene 2017 37 :1049 - 1061; October 30, 2017; 10.1038/onc.2017.403


Abstract | Full Text

Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia

F Peng, J-H Wang, W-J Fan, Y-T Meng, M-M Li et al.

Oncogene 2017 37 :1062 - 1074; November 06, 2017; 10.1038/onc.2017.368


Abstract | Full Text

CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2

M Qi, M Jiao, X Li, J Hu, L Wang et al.

Oncogene 2017 37 :1075 - 1085; November 06, 2017; 10.1038/onc.2017.380


Abstract | Full Text

DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma

Y Zhou, L Wang, X Ban, T Zeng, Y Zhu et al.

Oncogene 2017 37 :1086 - 1094; November 06, 2017; 10.1038/onc.2017.383


Abstract | Full Text

Intracellular mature IL-37 suppresses tumor metastasis via inhibiting Rac1 activation

Y Li, M Zhao, C Guo, H Chu, W Li et al.

Oncogene 2017 37 :1095 - 1106; November 06, 2017; 10.1038/onc.2017.405


Abstract | Full Text

Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia

D A Almiron Bonnin, M C Havrda, M C Lee, H Liu, Z Zhang et al.

Oncogene 2017 37 :1107 - 1118; November 20, 2017; 10.1038/onc.2017.404


Abstract | Full Text


Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia

F Peng, J-H Wang, W-J Fan, Y-T Meng, M-M Li et al.

Oncogene 2017 37 :1119 - 1119; December 18, 2017; 10.1038/onc.2017.407


Abstract | Full Text

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