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| | | | Volume 37, Issue 7 (February 2018) | | In this issue Reviews Original Articles Short Communication Also new AOP | Advertisement | The new SRG rat™, is a Sprague-Dawley SCID rat with knockouts in the Rag2 and Il2rgamma genes which lacks B-cells, T-cells, and NK-cells. The SRG rat enables tumor cell line & PDX studies that are inefficient or not feasible in mouse. Tumors grow ~10x larger enabling PDX establishment and efficacy studies in a single passage, powerfully shortening timelines. Can the SRG rat can overcome limitations of mouse models? AACR posters & data | | | | | | | | | Reviews | | | Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics A J Lucanus & G W Yip Oncogene 2017 37 :833 - 838; October 23, 2017; 10.1038/onc.2017.406 Abstract | Full Text | | | | | Molecular genetics and cellular events of K-Ras-driven tumorigenesis G G Jinesh, V Sambandam, S Vijayaraghavan, K Balaji et al. Oncogene 2017 37 :839 - 846; October 23, 2017; 10.1038/onc.2017.377 Abstract | Full Text | | Original Articles | | | Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB A García-Mariscal, H Li, E Pedersen, K Peyrollier, K M Ryan et al. Oncogene 2017 37 :847 - 860; October 23, 2017; 10.1038/onc.2017.333 Abstract | Full Text | | | | | EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1 H J Cho, Y-S Hwang, J Yoon, M Lee, H G Lee et al. Oncogene 2017 37 :861 - 872; October 23, 2017; 10.1038/onc.2017.386 Abstract | Full Text | | | | | IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma Y Qiao, C Zhang, A Li, D Wang, Z Luo et al. Oncogene 2017 37 :873 - 883; October 23, 2017; 10.1038/onc.2017.387 Abstract | Full Text | | | | | MiR-22 sustains NLRP3 expression and attenuates H. pylori-induced gastric carcinogenesis S Li, X Liang, L Ma, L Shen, T Li et al. Oncogene 2017 37 :884 - 896; October 23, 2017; 10.1038/onc.2017.381 Abstract | Full Text | | | | | Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition P Dietrich, S Kuphal, T Spruss, C Hellerbrand et al. Oncogene 2017 37 :897 - 911; October 23, 2017; 10.1038/onc.2017.391 Abstract | Full Text | | | | | SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer H Zhou, Y Qin, S Ji, J Ling, J Fu et al. Oncogene 2017 37 :912 - 923; October 23, 2017; 10.1038/onc.2017.393 Abstract | Full Text | | | | | Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation V L Sodi, Z A Bacigalupa, C M Ferrer, J V Lee, W A Gocal et al. Oncogene 2017 37 :924 - 934; October 23, 2017; 10.1038/onc.2017.395 Abstract | Full Text | | | | | Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation F Shi, L Shang, L-Y Yang, Y-Y Jiang, X-M Wang et al. Oncogene 2017 37 :935 - 943; October 23, 2017; 10.1038/onc.2017.399 Abstract | Full Text | | | | | Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors D Araiza-Olivera, Y Feng, G Semenova, T Y Prudnikova, J Rhodes et al. Oncogene 2017 37 :944 - 952; October 23, 2017; 10.1038/onc.2017.400 Abstract | Full Text | | | | | Activation of PPARa by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/ß-catenin pathway J Xue, W Zhu, J Song, Y Jiao, J Luo et al. Oncogene 2017 37 :953 - 962; October 23, 2017; 10.1038/onc.2017.401 Abstract | Full Text | | Short Communication | | | Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism E Cuyàs, S Fernández-Arroyo, S Verdura, R Á-F García, J Stursa et al. Oncogene 2017 37 :963 - 970; October 23, 2017; 10.1038/onc.2017.367 Abstract | Full Text | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com | | | | | | | | Please note that you need to be a subscriber or site-licence holder to enjoy full-text access to Oncogene. In order to do so, please purchase a subscription. 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