Thursday, February 15, 2018

Oncogene - Table of Contents alert Volume 37 Issue 7

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Volume 37, Issue 7 (February 2018)

In this issue
Original Articles
Short Communication
Also new

The new SRG rat™, is a Sprague-Dawley SCID rat with knockouts in the Rag2 and Il2rgamma genes which lacks B-cells, T-cells, and NK-cells.

The SRG rat enables tumor cell line & PDX studies that are inefficient or not feasible in mouse. Tumors grow ~10x larger enabling PDX establishment and efficacy studies in a single passage, powerfully shortening timelines. Can the SRG rat can overcome limitations of mouse models? 

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Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics

A J Lucanus & G W Yip

Oncogene 2017 37 :833 - 838; October 23, 2017; 10.1038/onc.2017.406


Abstract | Full Text

Molecular genetics and cellular events of K-Ras-driven tumorigenesis

G G Jinesh, V Sambandam, S Vijayaraghavan, K Balaji et al.

Oncogene 2017 37 :839 - 846; October 23, 2017; 10.1038/onc.2017.377


Abstract | Full Text

Original Articles

Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

A García-Mariscal, H Li, E Pedersen, K Peyrollier, K M Ryan et al.

Oncogene 2017 37 :847 - 860; October 23, 2017; 10.1038/onc.2017.333


Abstract | Full Text

EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1

H J Cho, Y-S Hwang, J Yoon, M Lee, H G Lee et al.

Oncogene 2017 37 :861 - 872; October 23, 2017; 10.1038/onc.2017.386


Abstract | Full Text

IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma

Y Qiao, C Zhang, A Li, D Wang, Z Luo et al.

Oncogene 2017 37 :873 - 883; October 23, 2017; 10.1038/onc.2017.387


Abstract | Full Text

MiR-22 sustains NLRP3 expression and attenuates H. pylori-induced gastric carcinogenesis

S Li, X Liang, L Ma, L Shen, T Li et al.

Oncogene 2017 37 :884 - 896; October 23, 2017; 10.1038/onc.2017.381


Abstract | Full Text

Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition

P Dietrich, S Kuphal, T Spruss, C Hellerbrand et al.

Oncogene 2017 37 :897 - 911; October 23, 2017; 10.1038/onc.2017.391


Abstract | Full Text

SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer

H Zhou, Y Qin, S Ji, J Ling, J Fu et al.

Oncogene 2017 37 :912 - 923; October 23, 2017; 10.1038/onc.2017.393


Abstract | Full Text

Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation

V L Sodi, Z A Bacigalupa, C M Ferrer, J V Lee, W A Gocal et al.

Oncogene 2017 37 :924 - 934; October 23, 2017; 10.1038/onc.2017.395


Abstract | Full Text

Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation

F Shi, L Shang, L-Y Yang, Y-Y Jiang, X-M Wang et al.

Oncogene 2017 37 :935 - 943; October 23, 2017; 10.1038/onc.2017.399


Abstract | Full Text

Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors

D Araiza-Olivera, Y Feng, G Semenova, T Y Prudnikova, J Rhodes et al.

Oncogene 2017 37 :944 - 952; October 23, 2017; 10.1038/onc.2017.400


Abstract | Full Text

Activation of PPARa by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/ß-catenin pathway

J Xue, W Zhu, J Song, Y Jiao, J Luo et al.

Oncogene 2017 37 :953 - 962; October 23, 2017; 10.1038/onc.2017.401


Abstract | Full Text

Short Communication

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism

E Cuyàs, S Fernández-Arroyo, S Verdura, R Á-F García, J Stursa et al.

Oncogene 2017 37 :963 - 970; October 23, 2017; 10.1038/onc.2017.367


Abstract | Full Text

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