Friday, June 30, 2017

Cell Death and Disease - Table of Contents alert Volume 8, June 2017

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Cell Death and Disease


Volume 8, June 2017

In this issue
News and Commentaries
Original Articles
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News and Commentaries


Genes versus Environment: cytoplasmic BAP1 determines the toxic response to environmental stressors in mesothelioma

Ivano Amelio

Cell Death Dis 2017 8: e2907; 10.1038/cddis.2017.293

Full Text

BH3-only proteins: the thorny end of the ER stress response

Jason A Glab, Marcel Doerflinger and Hamsa Puthalakath

Cell Death Dis 2017 8: e2889; 10.1038/cddis.2017.283

Full Text



MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis

Julian Musa, Marie-Ming Aynaud, Olivier Mirabeau, Olivier Delattre and Thomas GP Grünewald

Cell Death Dis 2017 8: e2895; 10.1038/cddis.2017.244

Abstract | Full Text

Necroptosis in neurodegenerative diseases: a potential therapeutic target

Shuo Zhang, Mi-bo Tang, Hai-yang Luo, Chang-he Shi and Yu-ming Xu

Cell Death Dis 2017 8: e2905; 10.1038/cddis.2017.286

Abstract | Full Text

Original Articles


Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study

Rahul Agarwal, Yuan Cao, Klaus Hoffmeier, Nicolas Krezdorn, Lukas Jost, Alejandro Rodriguez Meisel, Ruth Jüngling, Francesco Dituri, Serena Mancarella, Björn Rotter, Peter Winter and Gianluigi Giannelli

Cell Death Dis 2017 8: e2867; 10.1038/cddis.2017.229

Abstract | Full Text

Inefficient differentiation response to cell cycle stress leads to genomic instability and malignant progression of squamous carcinoma cells

Pilar Alonso-Lecue, Isabel de Pedro, Vincent Coulon, Rut Molinuevo, Corina Lorz, Carmen Segrelles, Laura Ceballos, Daniel López-Aventín, Ana García-Valtuille, José M Bernal, Francisco Mazorra, Ramón M Pujol, Jesús Paramio, J Ramón Sanz, Ana Freije, Agustí Toll and Alberto Gandarillas

Cell Death Dis 2017 8: e2901; 10.1038/cddis.2017.259

Abstract | Full Text

The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth

Hyun Seung Ban, Bo-Kyung Kim, Hongsub Lee, Hwan Mook Kim, Dipesh Harmalkar, Miso Nam, Song-Kyu Park, Kiho Lee, Joon-Tae Park, Inhyub Kim, Kyeong Lee, Geum-Sook Hwang and Misun Won

Cell Death Dis 2017 8: e2843; 10.1038/cddis.2017.235

Abstract | Full Text

Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

Purnima Bhat, Graham Leggatt, Nigel Waterhouse and Ian H Frazer

Cell Death Dis 2017 8: e2836; 10.1038/cddis.2017.67

Abstract | Full Text

The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke

Elisabetta Bonfanti, Paolo Gelosa, Marta Fumagalli, Leda Dimou, Francesca Viganò, Elena Tremoli, Mauro Cimino, Luigi Sironi and Maria P Abbracchio

Cell Death Dis 2017 8: e2871; 10.1038/cddis.2017.256

Abstract | Full Text

MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis

Qing Chen, Dan Yin, Yong Zhang, Lei Yu, Xue-Dong Li, Zheng-Jun Zhou, Shao-Lai Zhou, Dong-Mei Gao, Jie Hu, Cheng Jin, Zheng Wang, Ying-Hong Shi, Ya Cao, Jia Fan, Zhi Dai and Jian Zhou

Cell Death Dis 2017 8: e2906; 10.1038/cddis.2017.142

Abstract | Full Text

MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion

Xin Chen, Xue-Mei Jiang, Lin-Jing Zhao, Lin-Lin Sun, Mei-Ling Yan, You Tian, Shuai Zhang, Ming-Jing Duan, Hong-Mei Zhao, Wen-Rui Li, Yang-Yang Hao, Li-Bo Wang, Qiao-Jie Xiong and Jing Ai

Cell Death Dis 2017 8: e2850; 10.1038/cddis.2017.243

Abstract | Full Text

The putative tumor suppressor microRNA-30a-5p modulates clear cell renal cell carcinoma aggressiveness through repression of ZEB2

Zhenhua Chen, Jiaxing Zhang, Zhiling Zhang, Zihao Feng, Jinhuan Wei, Jun Lu, Yong Fang, Yanping Liang, Junjie Cen, Yihui Pan, Yong Huang, Fangjian Zhou, Wei Chen and Junhang Luo

Cell Death Dis 2017 8: e2859; 10.1038/cddis.2017.252

Abstract | Full Text

Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death

Emarndeena H Cheteh, Martin Augsten, Helene Rundqvist, Julie Bianchi, Victoria Sarne, Lars Egevad, Vladimir JN Bykov, Arne Östman and Klas G Wiman

Cell Death Dis 2017 8: e2848; 10.1038/cddis.2017.225

Abstract | Full Text

Nicotine protects rat hypoglossal motoneurons from excitotoxic death via downregulation of connexin 36

Silvia Corsini, Maria Tortora, Rossana Rauti and Andrea Nistri

Cell Death Dis 2017 8: e2881; 10.1038/cddis.2017.232

Abstract | Full Text

Knockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia

Luciana De Luca, Stefania Trino, Ilaria Laurenzana, Daniela Tagliaferri, Geppino Falco, Vitina Grieco, Gabriella Bianchino, Filomena Nozza, Valentina Campia, Francesca D'Alessio, Francesco La Rocca, Antonella Caivano, Oreste Villani, Daniela Cilloni, Pellegrino Musto and Luigi Del Vecchio

Cell Death Dis 2017 8: e2849; 10.1038/cddis.2017.253

Abstract | Full Text

Single-cell time-lapse imaging of intracellular O2 in response to metabolic inhibition and mitochondrial cytochrome-c release

Heiko Düssmann, Sergio Perez-Alvarez, Ujval Anilkumar, Dmitri B Papkovsky and Jochen HM Prehn

Cell Death Dis 2017 8: e2853; 10.1038/cddis.2017.247

Abstract | Full Text

MicroRNA-26a/cyclin-dependent kinase 5 axis controls proliferation, apoptosis and in vivo tumor growth of diffuse large B-cell lymphoma cell lines

Floriana Maria Farina, Alessandra Inguscio, Paolo Kunderfranco, Alice Cortesi, Leonardo Elia and Manuela Quintavalle

Cell Death Dis 2017 8: e2890; 10.1038/cddis.2017.291

Abstract | Full Text

The NF-κB1 is a key regulator of acute but not chronic renal injury

Amy Fearn, Gerhard R Situmorang, Christopher Fox, Fiona Oakley, Rachel Howarth, Caroline L Wilson, Agklinta Kiosia, Michael G Robson, Derek A Mann, Anna Moles and Neil S Sheerin

Cell Death Dis 2017 8: e2883; 10.1038/cddis.2017.233

Abstract | Full Text

A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling

Jemma Gatliff, Daniel A East, Aarti Singh, Maria Soledad Alvarez, Michele Frison, Ivana Matic, Caterina Ferraina, Natalie Sampson, Federico Turkheimer and Michelangelo Campanella

Cell Death Dis 2017 8: e2896; 10.1038/cddis.2017.186

Abstract | Full Text

Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia–reperfusion injury

Mian Ge, Weifeng Yao, Dongdong Yuan, Shaoli Zhou, Xi Chen, Yihan Zhang, Haobo Li, Zhengyuan Xia and Ziqing Hei

Cell Death Dis 2017 8: e2841; 10.1038/cddis.2017.236

Abstract | Full Text

Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons

Cristian Gerónimo-Olvera, Teresa Montiel, Ruth Rincon-Heredia, Susana Castro-Obregón and Lourdes Massieu

Cell Death Dis 2017 8: e2911; 10.1038/cddis.2017.299

Abstract | Full Text

P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo

Chao Gu, Yan Zhang, Qingsong Hu, Jiayuan Wu, Haigang Ren, Chun-Feng Liu and Guanghui Wang

Cell Death Dis 2017 8: e2858; 10.1038/cddis.2017.250

Abstract | Full Text

Titanium particle-induced osteogenic inhibition and bone destruction are mediated by the GSK-3β/β-catenin signal pathway

Ye Gu, Zhirong Wang, Jiawei Shi, Liangliang Wang, Zhenyang Hou, Xiaobin Guo, Yunxia Tao, Xiexing Wu, Wei Zhou, Yu Liu, Wen Zhang, Yaozeng Xu, Huilin Yang, Feng Xue and Dechun Geng

Cell Death Dis 2017 8: e2878; 10.1038/cddis.2017.275

Abstract | Full Text

LISPRO mitigates β-amyloid and associated pathologies in Alzheimer’s mice

Ahsan Habib, Darrell Sawmiller, Song Li, Yang Xiang, David Rongo, Jun Tian, Huayan Hou, Jin Zeng, Adam Smith, Shengnuo Fan, Brian Giunta, Takashi Mori, Glenn Currier, Douglas Ronald Shytle and Jun Tan

Cell Death Dis 2017 8: e2880; 10.1038/cddis.2017.279

Abstract | Full Text

Upconversion nanoparticle-mediated photodynamic therapy induces autophagy and cholesterol efflux of macrophage-derived foam cells via ROS generation

Xiaobo B Han, Hongxia X Li, Yueqing Q Jiang, Hao Wang, Xuesong S Li, Jiayuan Y Kou, Yinghong H Zheng, Zhongni N Liu, Hong Li, Jing Li, Dou Dou, You Wang, Ye Tian and Liming M Yang

Cell Death Dis 2017 8: e2864; 10.1038/cddis.2017.242

Abstract | Full Text

Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells

Tinka Haydn, Eric Metzger, Roland Schuele and Simone Fulda

Cell Death Dis 2017 8: e2879; 10.1038/cddis.2017.239

Abstract | Full Text

Heme oxygenase-1 derived carbon monoxide suppresses Aβ 1–42 toxicity in astrocytes

Nishani T Hettiarachchi, John P Boyle, Mark L Dallas, Moza M Al-Owais, Jason L Scragg and Chris Peers

Cell Death Dis 2017 8: e2884; 10.1038/cddis.2017.276

Abstract | Full Text

Gene knockout of Zmym3 in mice arrests spermatogenesis at meiotic metaphase with defects in spindle assembly checkpoint

Xiangjing Hu, Bin Shen, Shangying Liao, Yan Ning, Longfei Ma, Jian Chen, Xiwen Lin, Daoqin Zhang, Zhen Li, Chunwei Zheng, Yanmin Feng, Xingxu Huang and Chunsheng Han

Cell Death Dis 2017 8: e2910; 10.1038/cddis.2017.228

Abstract | Full Text

Bilirubin neurotoxicity is associated with proteasome inhibition

Hongbiao Huang, Mingxing Guo, Ningning Liu, Chong Zhao, Haoyu Chen, Xiaoli Wang, Siyan Liao, Ping Zhou, Yuning Liao, Xin Chen, Xiaoying Lan, Jinghong Chen, Dacai Xu, Xiaofen Li, Xianping Shi, Li Yu, Yuqiang Nie, Xuejun Wang, Chang-E Zhang and Jinbao Liu

Cell Death Dis 2017 8: e2877; 10.1038/cddis.2017.274

Abstract | Full Text

AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer

Dandan Huang, Xingzhi Feng, Yiting Liu, Yanhong Deng, Hao Chen, Daici Chen, Lekun Fang, Yue Cai, Huanliang Liu, Lei Wang, Jianping Wang and Zihuan Yang

Cell Death Dis 2017 8: e2894; 10.1038/cddis.2017.282

Abstract | Full Text

Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu

Yvonne Huber, Nadine Gehrke, Jana Biedenbach, Susanne Helmig, Perikles Simon, Beate K Straub, Ina Bergheim, Tobias Huber, Detlef Schuppan, Peter R Galle, Marcus A Wörns, Marcus Schuchmann and Jörn M Schattenberg

Cell Death Dis 2017 8: e2893; 10.1038/cddis.2017.266

Abstract | Full Text

In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects

Tongmeng Jiang, Guojie Xu, Qiuyan Wang, Lihui Yang, Li Zheng, Jinmin Zhao and Xingdong Zhang

Cell Death Dis 2017 8: e2851; 10.1038/cddis.2017.215

Abstract | Full Text

Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways

Huijuan Jiang, Yiqing Wang, Meiling Ai, Haowei Wang, Zhijiao Duan, Huanan Wang, Li Zhao, Jiang Yu, Yanqing Ding and Shuang Wang

Cell Death Dis 2017 8: e2862; 10.1038/cddis.2017.258

Abstract | Full Text

Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury

Aoi Kaneko, Sumiko Kiryu-Seo, Sakiko Matsumoto and Hiroshi Kiyama

Cell Death Dis 2017 8: e2847; 10.1038/cddis.2017.212

Abstract | Full Text

Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression

Shin Kasai, Yoshiyuki Furuichi, Norie Ando, Keiko Kagami, Masako Abe, Takaya Nakane, Kumiko Goi, Takeshi Inukai, Sei Saitoh, Shinichi Ohno, Shogo Okazaki, Osamu Nagano, Hideyuki Saya and Kanji Sugita

Cell Death Dis 2017 8: e2857; 10.1038/cddis.2017.249

Abstract | Full Text

BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer

Chun-mei Kuang, Xiang Fu, Yi-jun Hua, Wen-di Shuai, Zhi-hua Ye, Yingchang Li, Qi-hua Peng, Yi-zhuo Li, Shuai Chen, Chao-nan Qian, Wenlin Huang and Ran-yi Liu

Cell Death Dis 2017 8: e2874; 10.1038/cddis.2017.271

Abstract | Full Text

KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL

Ibrahim Cagri Kurt, Ilknur Sur, Ezgi Kaya, Ahmet Cingoz, Selena Kazancioglu, Zeynep Kahya, Omer Duhan Toparlak, Filiz Senbabaoglu, Zeynep Kaya, Ezgi Ozyerli, Sercin Karahüseyinoglu, Nathan A Lack, Zeynep H Gümüs, Tamer T Onder and Tugba Bagci-Onder

Cell Death Dis 2017 8: e2897; 10.1038/cddis.2017.288

Abstract | Full Text

Simvastatin treatment boosts benefits of apoptotic cell infusion in murine lung fibrosis

Ye-JI Lee, Meung-Joo Kim, Young-So Yoon, Youn-Hee Choi, Hee-Sun Kim and Jihee Lee Kang

Cell Death Dis 2017 8: e2860; 10.1038/cddis.2017.260

Abstract | Full Text

Long non-coding RNA ATB promotes malignancy of esophageal squamous cell carcinoma by regulating miR-200b/Kindlin-2 axis

Zhongwen Li, Xiaoliang Wu, Ling Gu, Qi Shen, Wen Luo, Chuangzhong Deng, Qianghua Zhou, Xinru Chen, Yanjie Li, ZuanFu Lim, Xing Wang, Jiahong Wang and Xianzi Yang

Cell Death Dis 2017 8: e2888; 10.1038/cddis.2017.245

Abstract | Full Text

Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer

Yang Li, Zheng Sun, Bing Liu, Yujia Shan, Lifen Zhao and Li Jia

Cell Death Dis 2017 8: e2892; 10.1038/cddis.2017.281

Abstract | Full Text

Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells

Rafik Mansouri, Yohann Jouan, Eric Hay, Claudine Blin-Wakkach, Monique Frain, Agnès Ostertag, Carole Le Henaff, Caroline Marty, Valérie Geoffroy, Pierre J Marie, Martine Cohen-Solal and Dominique Modrowski

Cell Death Dis 2017 8: e2902; 10.1038/cddis.2017.287

Abstract | Full Text

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury

Sofie Martens, Manhyung Jeong, Wulf Tonnus, Friederike Feldmann, Sam Hofmans, Vera Goossens, Nozomi Takahashi, Jan Hinrich Bräsen, Eun-Woo Lee, Pieter Van der Veken, Jurgen Joossens, Koen Augustyns, Simone Fulda, Andreas Linkermann, Jaewhan Song and Peter Vandenabeele

Cell Death Dis 2017 8: e2904; 10.1038/cddis.2017.298

Abstract | Full Text

Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

Lauren J Maskell, Kashif Qamar, Aram A Babakr, Thomas A Hawkins, Richard J Heads and Vishwanie S Budhram-Mahadeo

Cell Death Dis 2017 8: e2861; 10.1038/cddis.2017.185

Abstract | Full Text

Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice

Tie-Gang Meng, Meng-Wen Hu, Xue-Shan Ma, Lin Huang, Qiu-Xia Liang, Yue Yuan, Yi Hou, Hongmei Wang, Heide Schatten, Zhen-Bo Wang and Qing-Yuan Sun

Cell Death Dis 2017 8: e2846; 10.1038/cddis.2017.231

Abstract | Full Text

ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65

Jun Meng, Zhenyu Yao, Yaqing He, Renli Zhang, Yanwei Zhang, Xiangjie Yao, Hong Yang, Long Chen, Zhen Zhang, Hailong Zhang, Xueqin Bao, Gang Hu, Tangchun Wu and Jinquan Cheng

Cell Death Dis 2017 8: e2866; 10.1038/cddis.2017.257

Abstract | Full Text

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption

Stefan Meyer, Adam Stevens, Roberto Paredes, Marion Schneider, Michael J Walker, Andrew J K Williamson, Maria-Belen Gonzalez-Sanchez, Stephanie Smetsers, Vineet Dalal, Hsiang Ying Teng, Daniel J White, Sam Taylor, Joanne Muter, Andrew Pierce, Chiara de Leonibus, Davy A P Rockx, Martin A Rooimans, Elaine Spooncer, Stacey Stauffer, Kajal Biswas, Barbara Godthelp, Josephine Dorsman, Peter E Clayton, Shyam K Sharan and Anthony D Whetton

Cell Death Dis 2017 8: e2875; 10.1038/cddis.2017.264

Abstract | Full Text

Mutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers

Chevaun D Morrison, Jenny C Chang, Ruth A Keri and William P Schiemann

Cell Death Dis 2017 8: e2899; 10.1038/cddis.2017.294

Abstract | Full Text

Ubiquitin-dependent regulation of Cdc42 by XIAP

Arun Murali, Jaeyoung Shin, Hajime Yurugi, Aswini Krishnan, Masato Akutsu, Alejandro Carpy, Boris Macek and Krishnaraj Rajalingam

Cell Death Dis 2017 8: e2900; 10.1038/cddis.2017.305

Abstract | Full Text

Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism

Ting Ni, Zihao He, Yuanyuan Dai, Jingyue Yao, Qinglong Guo and Libin Wei

Cell Death Dis 2017 8: e2865; 10.1038/cddis.2017.261

Abstract | Full Text

HIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination

Mayilaadumveettil Nishana, Namrata M Nilavar, Rupa Kumari, Monica Pandey and Sathees C Raghavan

Cell Death Dis 2017 8: e2852; 10.1038/cddis.2017.237

Abstract | Full Text

Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex

Debasish Paul, Suvankar Ghorai, U S Dinesh, Praveenkumar Shetty, Samit Chattopadhyay and Manas Kumar Santra

Cell Death Dis 2017 8: e2882; 10.1038/cddis.2017.270

Abstract | Full Text

Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice

Eric Press, Katanya C Alaga, Kevin Barr, Qing Shao, Felicitas Bosen, Klaus Willecke and Dale W Laird

Cell Death Dis 2017 8: e2845; 10.1038/cddis.2017.234

Abstract | Full Text

Ochratoxin A-induced autophagy in vitro and in vivo promotes porcine circovirus type 2 replication

Gang Qian, Dandan Liu, Junfa Hu, Fang Gan, Lili Hou, Xingxiang Chen and Kehe Huang

Cell Death Dis 2017 8: e2909; 10.1038/cddis.2017.303

Abstract | Full Text

Mitochondrial AKAP1 supports mTOR pathway and tumor growth

Laura Rinaldi, Maria Sepe, Rossella Delle Donne, Kristel Conte, Antonietta Arcella, Domenica Borzacchiello, Stefano Amente, Fernanda De Vita, Monia Porpora, Corrado Garbi, Maria A Oliva, Claudio Procaccini, Deriggio Faicchia, Giuseppe Matarese, Federica Zito Marino, Gaetano Rocco, Sara Pignatiello, Renato Franco, Luigi Insabato, Barbara Majello and Antonio Feliciello

Cell Death Dis 2017 8: e2842; 10.1038/cddis.2017.241

Abstract | Full Text

Reduced brain UCP2 expression mediated by microRNA-503 contributes to increased stroke susceptibility in the high-salt fed stroke-prone spontaneously hypertensive rat

Speranza Rubattu, Rosita Stanzione, Franca Bianchi, Maria Cotugno, Maurizio Forte, Floriana Della Ragione, Salvatore Fioriniello, Maurizio D'Esposito, Simona Marchitti, Michele Madonna, Simona Baima, Giorgio Morelli, Sebastiano Sciarretta, Luigi Sironi, Paolo Gelosa and Massimo Volpe

Cell Death Dis 2017 8: e2891; 10.1038/cddis.2017.278

Abstract | Full Text

Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis

Natalia Rukoyatkina, Elke Butt, Hariharan Subramanian, Viacheslav O Nikolaev, Igor Mindukshev, Ulrich Walter, Stepan Gambaryan and Peter M Benz

Cell Death Dis 2017 8: e2898; 10.1038/cddis.2017.290

Abstract | Full Text

Cytoprotective effect of neuropeptides on cancer stem cells: vasoactive intestinal peptide-induced antiapoptotic signaling

Konduru S Sastry, Aouatef Ismail Chouchane, Ena Wang, George Kulik, Francesco M Marincola and Lotfi Chouchane

Cell Death Dis 2017 8: e2844; 10.1038/cddis.2017.226

Abstract | Full Text

Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells

Xiang-Bin Song, Gang Liu, Fei Liu, Zhen-Gui Yan, Zhen-Yong Wang, Zong-Ping Liu and Lin Wang

Cell Death Dis 2017 8: e2863; 10.1038/cddis.2017.262

Abstract | Full Text

Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming

Shujuan Sun, Jia Liu, Meisong Zhao, Yingyan Han, Pingbo Chen, Qingqing Mo, Beibei Wang, Gang Chen, Yong Fang, Yuan Tian, Jianfeng Zhou, Ding Ma, Qinglei Gao and Peng Wu

Cell Death Dis 2017 8: e2870; 10.1038/cddis.2017.273

Abstract | Full Text

Long noncoding RNA UCA1 induced by SP1 promotes cell proliferation via recruiting EZH2 and activating AKT pathway in gastric cancer

Zhen-Qiang Wang, Qiang Cai, Lei Hu, Chang-Yu He, Jian-Fang Li, Zhi-Wei Quan, Bing-Ya Liu, Chen Li and Zheng-Gang Zhu

Cell Death Dis 2017 8: e2839; 10.1038/cddis.2017.143

Abstract | Full Text

Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

Yang Wang, Jing Zhang, Zhi-Hao Huang, Xiao-Hui Huang, Wei-Bin Zheng, Xing-Feng Yin, Yao-Lan Li, Bin Li and Qing-Yu He

Cell Death Dis 2017 8: e2876; 10.1038/cddis.2017.265

Abstract | Full Text

Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells

Jiankang Wang, Bingling Luo, Xiaobing Li, Wenhua Lu, Jing Yang, Yumin Hu, Peng Huang and Shijun Wen

Cell Death Dis 2017 8: e2887; 10.1038/cddis.2017.272

Abstract | Full Text

Role of peroxiredoxin2 downregulation in recurrent miscarriage through regulation of trophoblast proliferation and apoptosis

Fan Wu, Fuju Tian, Weihong Zeng, Xiaorui Liu, Jianxia Fan, Yi Lin and Yan Zhang

Cell Death Dis 2017 8: e2908; 10.1038/cddis.2017.301

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Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target

Ping Xie, Jun-Ping Yang, Yun Cao, Li-Xia Peng, Li-Sheng Zheng, Rui Sun, Dong-Fang Meng, Meng-Yao Wang, Yan Mei, Yuan-Yuan Qiang, Li Cao, Yan-Qun Xiang, Dong-Hua Luo, Jing-Ping Yun, Bi-Jun Huang, Li-Jun Jia and Chao-Nan Qian

Cell Death Dis 2017 8: e2834; 10.1038/cddis.2017.195

Abstract | Full Text

E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis

Tong-Peng Xu, Yan-Fen Wang, Wei-Liang Xiong, Pei Ma, Wen-Yu Wang, Wen-Ming Chen, Ming-De Huang, Rui Xia, Rong Wang, Er-Bao Zhang, Yan-Wen Liu, Wei De and Yong-Qian Shu

Cell Death Dis 2017 8: e2837; 10.1038/cddis.2017.205

Abstract | Full Text

RGD-modified oncolytic adenovirus-harboring shPKM2 exhibits a potent cytotoxic effect in pancreatic cancer via autophagy inhibition and apoptosis promotion

Yanni Xu, Liang Chu, Sujing Yuan, Yuanqin Yang, Yu Yang, Bin Xu, Kangjian Zhang, Xin-Yuan Liu, Ruwei Wang, Ling Fang, Zhinan Chen and Zongsuo Liang

Cell Death Dis 2017 8: e2835; 10.1038/cddis.2017.230

Abstract | Full Text

Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition

Yuyao Yin, Mingming Zhang, Robert Gregory Dorfman, Yang Li, Zhenguo Zhao, Yida Pan, Qian Zhou, Shan Huang, Shimin Zhao, Yuling Yao and Xiaoping Zou

Cell Death Dis 2017 8: e2856; 10.1038/cddis.2016.457

Abstract | Full Text

Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype

Christina A Young, Ellen A Rorke, Gautam Adhikary, Wen Xu and Richard L Eckert

Cell Death Dis 2017 8: e2840; 10.1038/cddis.2017.238

Abstract | Full Text

Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling

Huijun Zeng, Zhao Yang, Ningbo Xu, Boyang Liu, Zhao Fu, Changlin Lian and Hongbo Guo

Cell Death Dis 2017 8: e2885; 10.1038/cddis.2017.248

Abstract | Full Text

Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis

Ting Zhang, Ping Yin, Zichen Zhang, Banglao Xu, Di Che, Zhiyu Dai, Chang Dong, Ping Jiang, Honghai Hong, Zhonghan Yang, Ti Zhou, Jianyong Shao, Zumin Xu, Xia Yang and Guoquan Gao

Cell Death Dis 2017 8: e2838; 10.1038/cddis.2017.114

Abstract | Full Text

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis

Zili Zhang, Zhen Yao, Shifeng Zhao, Jiangjuan Shao, Anping Chen, Feng Zhang and Shizhong Zheng

Cell Death Dis 2017 8: e2886; 10.1038/cddis.2017.255

Abstract | Full Text

EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway

Fei Zhang, Shanshan Xiang, Yang Cao, Maolan Li, Qiang Ma, Haibin Liang, Huaifeng Li, Yuanyuan Ye, Yijian Zhang, Lin Jiang, Yunping Hu, Jian Zhou, Xuefeng Wang, Yong Zhang, Lei Nie, Xiao Liang, Wei Gong and Yingbin Liu

Cell Death Dis 2017 8: e2868; 10.1038/cddis.2017.263

Abstract | Full Text

The role of MAP2 kinases and p38 kinase in acute murine liver injury models

Jun Zhang, Robert W M Min, Khanh Le, Sheng Zhou, Mariam Aghajan, Tin A Than, Sanda Win and Neil Kaplowitz

Cell Death Dis 2017 8: e2903; 10.1038/cddis.2017.295

Abstract | Full Text

EGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy

Kunming Zhao, Miao Yu, Yifu Zhu, Dong Liu, Qiong Wu and Ying Hu

Cell Death Dis 2017 8: e2869; 10.1038/cddis.2017.268

Abstract | Full Text

MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway

Zhen Zheng, Jia-Quan Qu, Hong-Mei Yi, Xu Ye, Wei Huang, Ta Xiao, Jiao-Yang Li, Yuan-Yuan Wang, Juan Feng, Jin-Feng Zhu, Shan-Shan Lu, Hong Yi and Zhi-Qiang Xiao

Cell Death Dis 2017 8: e2855; 10.1038/cddis.2017.211

Abstract | Full Text

Cystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units

Jing Zou, Zhaoyu Chen, Xiaobo Wei, Zhigang Chen, Yongmei Fu, Xiaoyan Yang, Dan Chen, Rui Wang, Peter Jenner, Jia-Hong Lu, Min Li, Zhuohua Zhang, Beisha Tang, Kunlin Jin and Qing Wang

Cell Death Dis 2017 8: e2854; 10.1038/cddis.2017.240

Abstract | Full Text



EMT-Regulome: a database for EMT-related regulatory interactions, motifs and network

Zhangxiang Zhao, Wenbin Zhou, Yue Han, Fuduan Peng, Ruiping Wang, Ruihan Yu, Chengyu Wang, Haihai Liang, Zheng Guo and Yunyan Gu

Cell Death Dis 2017 8: e2872; 10.1038/cddis.2017.267

Full Text

A hypoxia-inducible factor 1α null splice variant lacking exon 10

Xiangyu Zhou, Weijia Zeng, Rui Peng and Hongyan Wang

Cell Death Dis 2017 8: e2873; 10.1038/cddis.2017.269

Full Text

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