Wednesday, May 24, 2017

Nature Reviews Cancer contents June 2017 Volume 17 Number 6 pp333-392

If you are unable to see the message below, click here to view.

Nature Reviews Cancer

June 2017 Volume 17 Number 6Advertisement
Nature Reviews Cancer cover
2015 2-year Impact Factor 34.244 Journal Metrics 2-year Median 27
In this issue
Research Highlights

Also this month
 Featured article:
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
Silvia von Karstedt, Antonella Montinaro & Henning Walczak

Find out how Ginger got her voice back.
Behind every patient stands thousands of scientists and researchers working together to develop life-saving treatments. So what happens when a patient meets the people that helped save her life? Watch as Ginger Tam, a professional singer and lung cancer patient, meets the researchers who worked on her cancer treatment. 

View the video

Recommend to library
Harvard Medical School Global & Continuing Education

Join Harvard faculty for a 1 year blended-learning program designed to provide deep knowledge of the cancer biology that shapes modern preventive & therapeutics approaches. In this program you will learn the latest educational approaches, challenges & opportunities as to how cancer biology research is shaping cutting edge therapies.

Explore the CBT Certificate Program Today!
7 Genomic methods that empower immuno-oncology trials

How can genomics provide new insights and shape the success of your immuno-oncology program? Download our complimentary insight brief to learn how genomics-based biomarker approaches, combined with bioinformatics expertise, enhance immuno-oncology programs.

September 17-19, 2017 | Seattle, WA, USA

Presented by: Adaptive Biotechnologies | Nature Immunology | Nature Medicine | Nature Biotechnology


Immunotherapy: T cells get a ride
p333 | doi:10.1038/nrc.2017.39

Tumorigenesis: Cancer as a symptom of evolution?
p373 | doi:10.1038/nrc.2017.33
A paper in Science by Tomasetti, Li and Vogelstein develops their 'bad luck' model further and explores how different sources of DNA mutation influence different cancer types.

Metastasis: The plastic state
p373 | doi:10.1038/nrc.2017.34
ZEB1-mediated epithelial-mesenchymal transition (EMT) and cellular plasticity promotes metastasis in pancreatic cancer.


Genetics: Gender-specific factors in cancer susceptibility | Immunotherapy: Programming T cells in situ

JOBS of the week
Assistant / Associate Editor for Cancer Immunology Research
American Association for Cancer Research (AACR)
Postdoctoral Fellow - Comparative Analysis of Cancer Genomes
Wellcome Trust Sanger Institute
Postdoctoral position available in Cancer Immunology and Immunotherapy at Weill Cornell Medicine in New York City
Weill Cornell Medicine
Post-doctoral position – Carolina Cancer Nanotechnology T32 Training program
The University of North Carolina
Professorship in Cancer Genomics
Ecole Polytechnique Fédérale de Lausanne (EPFL)
More Science jobs from
3rd World Congress on Thyroid Cancer
Boston, USA
More science events from
Nature Reviews Cancer: Poster on Multifaceted effects of the microenvironment on tumour progression

Available to download free online

Produced with support from 
Fluidigm Corporation 
The ETS family of oncogenic transcription factors in solid tumours
Gina M. Sizemore, Jason R. Pitarresi, Subhasree Balakrishnan & Michael C. Ostrowski
p337 | doi:10.1038/nrc.2017.20
Initially identified more than 30 years ago, the ETS family of transcription factors has been found to take part in all steps of tumorigenesis. This Review discusses the different mechanisms of ETS activation and the oncogenic implications of this activation, as well as how to target ETS factors in cancer treatment.
Abstract | Full Text | PDF

Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
Silvia von Karstedt, Antonella Montinaro & Henning Walczak
p352 | doi:10.1038/nrc.2017.28
Clinical trials testing activators of tumour necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) signalling in cancer have not met expectations. This Review discusses new insights that might explain clinical failure, but also provide the basis for harnessing TRAIL-Rs for cancer therapy.
Abstract | Full Text | PDF

The calcium-cancer signalling nexus
Gregory R. Monteith, Natalia Prevarskaya & Sarah J. Roberts-Thomson
p367 | doi:10.1038/nrc.2017.18
Changes in the calcium signal enable cells to achieve specific outcomes. In this Review, Monteith et al. describe how the remodelling of the expression and activity of calcium channels and pumps in cancer cells can influence tumour progression.
Abstract | Full Text | PDF

RNA editing-dependent epitranscriptome diversity in cancer stem cells
Qingfei Jiang, Leslie A. Crews, Frida Holm & Catriona H. M. Jamieson
p381 | doi:10.1038/nrc.2017.23
This Review discusses the roles of deregulated RNA processing, including RNA methylation, RNA editing, RNA splicing and RNA binding protein activity, in cancer stem cells and highlights the potential of these events as biomarkers and therapeutic targets.
Abstract | Full Text | PDF

npj Precision Oncology is a new open access, online-only, peer-reviewed journal committed to publishing cutting-edge scientific research in all aspects of precision oncology from basic science to translational applications, to clinical medicine. The journal is part of the Nature Partner Journals series and published in partnership with The Hormel Institute, University of Minnesota.

Explore the benefits of submitting your manuscript.
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.

Find the latest scientific conferences, courses, meetings and symposia on For event advertising opportunities across the Nature Publishing Group portfolio please contact
More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your account at:
(You will need to log in to be recognised as a registrant).

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our feedback department

Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Springer Nature's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2017 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.

Springer Nature

No comments: