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| | | Influence of substrate modulus on gecko adhesion ▶ | | | Mena R. Klittich, Michael C. Wilson, Craig Bernard et al. | | | The gecko adhesion system fascinates biologists and materials scientists alike for its strong, reversible, glue-free, dry adhesion. Understanding the adhesion system’s … | | | | |
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| | | Tool use for corpse cleaning in chimpanzees ▶ | | | Edwin J. C. van Leeuwen, Katherine A. Cronin, Daniel B. M. Haun | | | For the first time, chimpanzees have been observed using tools to clean the corpse of a deceased group member. A female chimpanzee sat down at the dead body of a young male, … | | | | |
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| | | Hyaluronan synthesis by developing cortical neurons in vitro ▶ | | | Tania M. Fowke, Rashika N. Karunasinghe, Ji-Zhong Bai et al. | | | Hyaluronan is a linear glycosaminoglycan that forms the backbone of perineuronal nets around neurons in the cerebral cortex. However, it remains controversial whether neurons are … | | | | |
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| | | Worldwide circulation of HSV-2 × HSV-1 recombinant strains ▶ | | | David M. Koelle, Peter Norberg, Matthew P. Fitzgibbon et al. | | | Homo sapiens harbor two distinct, medically significant species of simplexviruses, herpes simplex virus (HSV)-1 and HSV-2, with estimated divergence 6–8 million years ago (MYA). … | | | | |
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| | | Heterogeneity assessment of functional T cell avidity ▶ | | | Kalliopi Ioannidou, Petra Baumgaertner, Philippe O. Gannon et al. | | | The potency of cellular immune responses strongly depends on T cell avidity to antigen. Yet, functional avidity measurements are rarely performed in patients, mainly due to the … | | | | |
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| | | Mona Lisa is always happy – and only sometimes sad ▶ | | | Emanuela Liaci, Andreas Fischer, Markus Heinrichs et al. | | | The worldwide fascination of da Vinci’s Mona Lisa has been dedicated to the emotional ambiguity of her face expression. In the present study we manipulated Mona Lisa’s mouth … | | | | |
| | | Auto-phosphorylation Represses Protein Kinase R Activity ▶ | | | Die Wang, Nicole A. de Weerd, Belinda Willard et al. | | | The central role of protein kinases in controlling disease processes has spurred efforts to develop pharmaceutical regulators of their activity. A rational strategy to achieve … | | | | |
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| | | Kinetic 15N-isotope effects on algal growth ▶ | | | Eivydas Andriukonis, Elena Gorokhova | | | Stable isotope labeling is a standard technique for tracing material transfer in molecular, ecological and biogeochemical studies. The main assumption in this approach is that … | | | | |
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| | | The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees? ▶ | | | Peter D. Walsh, Drishya Kurup, Dana L. Hasselschwert et al. | | | Could new oral vaccine technologies protect endangered wildlife against a rising tide of infectious disease? We used captive chimpanzees to test oral delivery of a rabies virus … | | | | |
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| | | Optogenetic control of the Dab1 signaling pathway ▶ | | | Liang Wang, Jonathan A. Cooper | | | The Reelin-Dab1 signaling pathway regulates development of the mammalian brain, including neuron migrations in various brain regions, as well as learning and memory in adults. … | | | | |
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| | | Emergence of linguistic laws in human voice ▶ | | | Iván González Torre, Bartolo Luque, Lucas Lacasa et al. | | | Linguistic laws constitute one of the quantitative cornerstones of modern cognitive sciences and have been routinely investigated in written corpora, or in the equivalent … | | | | |
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| | | Confocal imaging of mouse mandibular condyle cartilage ▶ | | | Y. He, M. Zhang, A. Y. Huang et al. | | | Mice are commonly used to study the temporomandibular joint (TMJ) and to model human TMJ disease. However, evaluating TMJ pathology in mice using standard histologic methods is … | | | | |
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| | | Human NDE1 splicing and mammalian brain development ▶ | | | S. Mosca, M. Raponi, A. Meneghello et al. | | | Exploring genetic and molecular differences between humans and other close species may be the key to explain the uniqueness of our brain and the selective pressures under which … | | | | |
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| | | D-Glutamate is metabolized in the heart mitochondria ▶ | | | Makoto Ariyoshi, Masumi Katane, Kenji Hamase et al. | | | D-Amino acids are enantiomers of L-amino acids and have recently been recognized as biomarkers and bioactive substances in mammals, including humans. In the present study, we … | | | | |
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| | | In vivo microsampling to capture the elusive exposome ▶ | | | Vincent Bessonneau, Jennifer Ings, Mark McMaster et al. | | | Loss and/or degradation of small molecules during sampling, sample transportation and storage can adversely impact biological interpretation of metabolomics data. In this study, … | | | | |
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| | | Physics of chewing in terrestrial mammals ▶ | | | Emmanuel Virot, Grace Ma, Christophe Clanet et al. | | | Previous studies on chewing frequency across animal species have focused on finding a single universal scaling law. Controversy between the different models has been aroused … | | | | |
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