Nature Reviews Neuroscience contents March 2017 Volume 18 Number 3 pp 127 - 192

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TABLE OF CONTENTS
March 2017 Volume 18 Number 3
2015 2-year Impact Factor 29.298 Journal Metrics 2-year Median 22	In this issue Research Highlights Reviews Perspectives Also this month  Featured article: Fractionating impulsivity: neuropsychiatric implications Jeffrey W. Dalley & Trevor W. Robbins
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RESEARCH HIGHLIGHTS Top Learning and memory: Space and time connections p127 | doi:10.1038/nrn.2017.11 Direct projections from the dorsal and intermediate CA1 to the medial prefrontal cortex in rats are crucial for the retrieval of temporal and spatial aspects of episodic memory, respectively. PDF Learning and memory: I remember it well... p128 | doi:10.1038/nrn.2017.12 Extended periods of exposure to emotional stimuli result in increased functional connectivity between the amygdala and the anterior hippocampus, which strengthens memory consolidation and subsequent recall of neutral stimuli experienced during this altered brain state. PDF Sensory systems: Sensational organization in the dorsal horn p128 | doi:10.1038/nrn.2017.9 This study dissects the complex interneuron networks that contribute to the processing of innocuous touch-information in the spinal cord. PDF Glia: A toxic reaction p130 | doi:10.1038/nrn.2017.13 Activated microglia induce a subtype of reactive astrocytes that is toxic to various neuronal types and oligodendrocytes and that is found in various neurological disorders. PDF IN BRIEF Prefrontal cortex: Down in front | Neurodegenerative disease: Losing the way | Behavioural neuroscience: Right on (social) cue | Cell biology of the neuron: Adding fuel to the firing | Synaptic transmission: Recycling regulators | Sleep and memory: REM sleep targets new synapses | Pain: Improving opioids | Neuromodulation: A circuit modulator PDF
REVIEWS		Top
Micro-connectomics: probing the organization of neuronal networks at the cellular scale Manuel Schröter, Ole Paulsen & Edward T. Bullmore p131 | doi:10.1038/nrn.2016.182 Micro-connectomics involves determining the principles of how neuronal networks are organized at the cellular level. In this Review, Schröter, Paulsen and Bullmore examine studies that have provided insight into the network organization of relatively small, as well as more complex, nervous systems. Abstract | Full Text | PDF
SHANK proteins: roles at the synapse and in autism spectrum disorder Patricia Monteiro & Guoping Feng p147 | doi:10.1038/nrn.2016.183 Mutations in the genes encoding the SH3 and multiple ankyrin repeat domains protein (SHANK) family have been linked to autism spectrum disorder, driving a wave of recent studies that aimed to dissect their functional roles in the brain. Monteiro and Feng describe recent findings that have begun to shed light on the important roles of SHANK proteins at the synapse. Abstract | Full Text | PDF | Supplementary information
Fractionating impulsivity: neuropsychiatric implications Jeffrey W. Dalley & Trevor W. Robbins p158 | doi:10.1038/nrn.2017.8 Impulsivity comes in various forms, with some forms considered more or less advantageous than others. Dalley and Robbins review the different types of impulsivity and their underlying neural mechanisms, and comment on the applicability of measures of impulsivity in research into psychiatric disorders. Abstract | Full Text | PDF
PERSPECTIVES		Top
OPINION A distributed, hierarchical and recurrent framework for reward-based choice Laurence T. Hunt & Benjamin Y. Hayden p172 | doi:10.1038/nrn.2017.7 In this Opinion article, Hunt and Hayden highlight that many of the models for reward-based choice are based on distinct component processes that occur in series and are functionally localized. They argue that, instead, such choice emerges from repeated computations that are undertaken in many brain areas. Abstract | Full Text | PDF
OPINION The contribution of the human posterior parietal cortex to episodic memory Carlo Sestieri, Gordon L. Shulman & Maurizio Corbetta p183 | doi:10.1038/nrn.2017.6 Recent human neuroimaging studies suggest that, in addition to its role in visuospatial and sensorimotor processes, the posterior parietal cortex (PPC) also plays an important part in episodic memory retrieval. Here, Sestieri, Shulman and Corbetta present a functional–anatomical model of the involvement of the PPC in memory retrieval. Abstract | Full Text | PDF
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