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February 2017 Volume 15 Number 2 | Advertisement | ||||||||||||||||||||||||||||||||||||
In this issue Research Highlights News and Analysis Reviews
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NEWS AND ANALYSIS | Top | ||||||||||||||||||||||||||||||||||||
GENOME WATCH You are where you live Samuel E. Kidman & Josephine M. Bryant p68 | doi:10.1038/nrmicro.2016.203 This month's Genome Watch discusses how whole-genome sequencing of bacteria from several body sites has provided insights into the spatial diversity of bacteria within patients. | |||||||||||||||||||||||||||||||||||||
REVIEWS | Top | ||||||||||||||||||||||||||||||||||||
Nuclear landscape of HIV-1 infection and integration Marina Lusic & Robert F. Siliciano p69 | doi:10.1038/nrmicro.2016.162 Entry into the nucleus and integration into the host cell are key steps during HIV-1 infection. In this Review, Lusic and Siliciano discuss viral and host factors that influence HIV-1 integration and how it can be targeted therapeutically. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
Cellulosomes: bacterial nanomachines for dismantling plant polysaccharides Lior Artzi, Edward A. Bayer & Sarah Moraïs p83 | doi:10.1038/nrmicro.2016.164 Cellulosomes are sophisticated multicomponent complexes that are used by bacteria to degrade cellulose from plant cell walls. In this review, Artzi, Bayer and Morais explore the structural and functional diversity of cellulosomes and their applications; for example, in microbial biofuel production. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
Candida albicans cell-type switching and functional plasticity in the mammalian host Suzanne M. Noble, Brittany A. Gianetti & Jessica N. Witchley p96 | doi:10.1038/nrmicro.2016.157 In this Review, Noble and colleagues discuss the characteristics of the classic cell types of Candida albicans — yeast, hyphae, pseudohyphae and chlamydospores — as well as newly identified yeast-like morphotypes, including grey and gastrointestinally induced transition (GUT) cell types, and highlight emerging knowledge about their associations with different host niches and propensities towards virulence versus commensalism. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer Aurélie Gagnaire, Bertrand Nadel, Didier Raoult, Jacques Neefjes & Jean-Pierre Gorvel p109 | doi:10.1038/nrmicro.2016.171 In addition to viruses, bacteria such as Helicobacter pylori and Salmonella enterica subsp. enterica serovar Typhi have been linked to cancer development. Progress has been made in our understanding of how bacterial effectors contribute to cancer directly by influencing host cell signalling pathways and indirectly by causing tissue damage and inflammatory responses. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
Corrigendum: A new view into prokaryotic cell biology from electron cryotomography Catherine M. Oikonomou & Grant J. Jensen p128 | doi:10.1038/nrmicro.2016.195 Full Text | PDF | |||||||||||||||||||||||||||||||||||||
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