The EMBO Journal Table of Contents for 15 December 2016; Vol. 35, No. 24

15 December 2016 | Volume 35, Number 24 Submit Table of Contents Editorial Commentary Obituary News & Views Review Articles Volume 35, Number 24 Editorial Preparing for Preprints Preprints reduce delays in sharing research results. With appropriate policies to encourage use and quality assurance mechanisms, their widespread adoption would benefit everyone in the scientific community. Bernd Pulverer Published online 01.12.2016 Commentary Preprint Déjà Vu Preprints allow stable archiving and sharing of research findings with minimal delay, complementing peer‐reviewed journals. In the physical sciences, preprints are an integral part the scientific process. Here, the initiator of the concept describes why and how preprints can work in biology. Paul Ginsparg Published online 19.10.2016 Obituary Susan Lee Lindquist (1949–2016)—pioneer in the study of cellular protein folding and disease Franz‐Ulrich Hartl Published online 05.12.2016 News & Views Bimodal skin progenitors—a matter of place and time A new study uncovers that hair follicle position and cycling regulate the proliferation of skin epithelial cells. Svetlana Ulyanchenko and Kim B Jensen Published online 14.11.2016 Zika virus NS1, a pathogenicity factor with many faces Two new structural studies on the enigmatic Zika virus NS1 protein reveal its unique surface properties, with functional implications and potential significance for vaccine development. Rolf Hilgenfeld Published online 27.10.2016 Review The diverse and expanding role of mass spectrometry in structural and molecular biology Starting from a historical perspective, Albert Heck and colleagues showcase how state‐of‐the‐art mass spectrometry approaches have evolved into powerful tools to elucidate structure and function of proteins and protein complexes. Philip Lössl, Michiel van de Waterbeemd, and Albert JR Heck Published online 26.10.2016 Articles Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling Transgenic “skinbow” multicolour lineage tracing and mathematical modelling reveal two distinct modes of progenitor cell proliferation, controlled by relative hair follicle position and cycle phase. Edwige Roy, Zoltan Neufeld, Luca Cerone, Ho Yi Wong, Samantha Hodgson, Jean Livet, and Kiarash Khosrotehrani Published online 21.10.2016 Rapid movement and transcriptional re‐localization of human cohesin on DNA Human cohesin rings entrap DNA and rapidly translocate along DNA by diffusion. Cohesin can pass over small DNA‐bound proteins but is constrained in its movement by transcription and DNA‐bound CCCTC‐binding factor (CTCF). Iain F Davidson, Daniela Goetz, Maciej P Zaczek, Maxim I Molodtsov, Pim J Huis in 't Veld, Florian Weissmann, Gabriele Litos, David A Cisneros, Maria Ocampo‐Hafalla, Rene Ladurner, Frank Uhlmann, Alipasha Vaziri, and Jan‐Michael Peters Published online 31.10.2016 Cohesin acetylation and Wapl‐Pds5 oppositely regulate translocation of cohesin along DNA Single‐molecule observations of cohesin translocation in vitro and in Xenopus egg extracts define its dependence on regulatory factors and DNA replication. Mai Kanke, Eri Tahara, Pim J Huis in't Veld, and Tomoko Nishiyama Published online 21.11.2016 Seipin regulates ER–lipid droplet contacts and cargo delivery Seipin, mutated in severe congenital lipodystrophy (BSCL2), is an ER–lipid droplet (LD) contact protein that regulates the extent of ER–LD contacts and facilitates incorporation of lipid and protein cargo into maturing LDs. Veijo T Salo, Ilya Belevich, Shiqian Li, Leena Karhinen, Helena Vihinen, Corinne Vigouroux, Jocelyne Magré, Christoph Thiele, Maarit Hölttä‐Vuori, Eija Jokitalo, and Elina Ikonen Published online 22.11.2016   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2016 by the European Molecular Biology Organisation.