TABLE OF CONTENTS
| | | | Volume 30, Issue 12 (December 2016) | | In this issue Reviews Original Articles Letters to the Editor Corrigendum
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Explore the benefits of submitting your next research article. | | | | | | Reviews | Top | | Human memory B cellsM Seifert and R Küppers Leukemia 2016 30: 2283-2292; advance online publication, August 8, 2016; 10.1038/leu.2016.226 Abstract | Full Text | | | | B cells and macrophages pursue a common path toward the development and progression of chronic lymphocytic leukemiaG Galletti, F Caligaris-Cappio and M T S Bertilaccio Leukemia 2016 30: 2293-2301; advance online publication, September 28, 2016; 10.1038/leu.2016.261 Abstract | Full Text | | Original Articles | Top | | ACUTE MYELOID LEUKEMIA | Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cellsB Mitton, H -D Chae, K Hsu, R Dutta, G Aldana-Masangkay, R Ferrari, K Davis, B C Tiu, A Kaul, N Lacayo, G Dahl, F Xie, B X Li, M R Breese, E M Landaw, G Nolan, M Pellegrini, S Romanov, X Xiao and K M Sakamoto Leukemia 2016 30: 2302-2311; advance online publication, May 23, 2016; 10.1038/leu.2016.139 Abstract | Full Text | | | | ACUTE LYMPHOBLASTIC LEUKEMIA | Eye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse OPENR J M Bashford-Rogers, K A Nicolaou, J Bartram, N J Goulden, L Loizou, L Koumas, J Chi, M Hubank, P Kellam, P A Costeas and G S Vassiliou Leukemia 2016 30: 2312-2321; advance online publication, May 23, 2016; 10.1038/leu.2016.142 Abstract | Full Text | | | | MYELODYSPLASTIC SYNDROME | Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes OPENH Dolatshad, A Pellagatti, F G Liberante, M Llorian, E Repapi, V Steeples, S Roy, L Scifo, R N Armstrong, J Shaw, B H Yip, S Killick, R Kušec, S Taylor, K I Mills, K I Savage, C W J Smith and J Boultwood Leukemia 2016 30: 2322-2331; advance online publication, May 23, 2016; 10.1038/leu.2016.149 Abstract | Full Text | | | | CHRONIC MYELOPROLIFERATIVE NEOPLASMS | JAK2V617F-mutant megakaryocytes contribute to hematopoietic stem/progenitor cell expansion in a model of murine myeloproliferationH Zhan, Y Ma, C H S Lin and K Kaushansky Leukemia 2016 30: 2332-2341; advance online publication, May 2, 2016; 10.1038/leu.2016.114 Abstract | Full Text | | | | Splenomegaly, elevated alkaline phosphatase and mutations in the SRSF2/ASXL1/RUNX1 gene panel are strong adverse prognostic markers in patients with systemic mastocytosisM Jawhar, J Schwaab, D Hausmann, J Clemens, N Naumann, T Henzler, H-P Horny, K Sotlar, S O Schoenberg, N C P Cross, A Fabarius, W-K Hofmann, P Valent, G Metzgeroth and A Reiter Leukemia 2016 30: 2342-2350; advance online publication, July 15, 2016; 10.1038/leu.2016.190 Abstract | Full Text | | | | MOLECULAR TARGETS FOR THERAPY | Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivoP Storti, V Marchica, I Airoldi, G Donofrio, E Fiorini, V Ferri, D Guasco, K Todoerti, R Silbermann, J L Anderson, W Zhao, L Agnelli, M Bolzoni, E Martella, C Mancini, N Campanini, D M Noonan, P G Petronini, A Neri, F Aversa, G D Roodman and N Giuliani Leukemia 2016 30: 2351-2363; advance online publication, May 20, 2016; 10.1038/leu.2016.137 Abstract | Full Text | | | | EARLY PHASE STUDIES | Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignanciesZ A Hing, H Y J Fung, P Ranganathan, S Mitchell, D El-Gamal, J A Woyach, K Williams, V M Goettl, J Smith, X Yu, X Meng, Q Sun, T Cagatay, A M Lehman, D M Lucas, E Baloglu, S Shacham, M G Kauffman, J C Byrd, Y M Chook, R Garzon and R Lapalombella Leukemia 2016 30: 2364-2372; advance online publication, May 20, 2016; 10.1038/leu.2016.136 Abstract | Full Text | | | | CYTOGENETICS AND MOLECULAR GENETICS | Loss of Dnmt3b accelerates MLL-AF9 leukemia progressionY Zheng, H Zhang, Y Wang, X Li, P Lu, F Dong, Y Pang, S Ma, H Cheng, S Hao, F Tang, W Yuan, X Zhang and T Cheng Leukemia 2016 30: 2373-2384; advance online publication, May 2, 2016; 10.1038/leu.2016.112 Abstract | Full Text | | | | Distinct genetic evolution patterns of relapsing diffuse large B-cell lymphoma revealed by genome-wide copy number aberration and targeted sequencing analysisD Juskevicius, T Lorber, J Gsponer, V Perrina, C Ruiz, F Stenner-Liewen, S Dirnhofer and A Tzankov Leukemia 2016 30: 2385-2395; advance online publication, May 20, 2016; 10.1038/leu.2016.135 Abstract | Full Text | | Letters to the Editor | Top | | Chronic myeloid leukemia patients call for quality and consistency when generics are introduced to treat their cancer OPENJ Geissler, G Sharf, J Cugurovic, R Padua, Š Narbutas, M Remic and V Venkatesh for the CML Advocates Network Leukemia 2016 30: 2396-2397; advance online publication, August 3, 2016; 10.1038/leu.2016.220 Full Text | | | | Anti-CD44 antibodies inhibit both mTORC1 and mTORC2: a new rationale supporting CD44-induced AML differentiation therapy OPENS Z Gadhoum, N Y Madhoun, A F Abuelela and J S Merzaban Leukemia 2016 30: 2397-2401; advance online publication, August 8, 2016; 10.1038/leu.2016.221 Full Text | | | | The novel PI3K-δ inhibitor TGR-1202 enhances Brentuximab Vedotin-induced Hodgkin lymphoma cell death via mitotic arrestS L Locatelli, G Careddu, G Inghirami, L Castagna, P Sportelli, A Santoro and C Carlo-Stella Leukemia 2016 30: 2402-2405; advance online publication, August 8, 2016; 10.1038/leu.2016.224 Full Text | | | | Molecular predictors of response in patients with myeloid neoplasms treated with lenalidomideE Negoro, T Radivoyevitch, C Polprasert, V Adema, N Hosono, H Makishima, B Przychodzen, C Hirsch, M J Clemente, A Nazha, V Santini, K L McGraw, A F List, F Sole, M A Sekeres and J P Maciejewski Leukemia 2016 30: 2405-2409; advance online publication, August 18, 2016; 10.1038/leu.2016.228 Full Text | | | | Dissection of CD20 regulation in lymphoma using RNAiM Słabicki, K S Lee, A Jethwa, L Sellner, F Sacco, T Walther, J Hüllein, S Dietrich, B Wu, D B Lipka, C C Oakes, S Mamidi, B Pyrzyńska, M Winiarska, M Oleś, M Seifert, C Plass, M Kirschfink, M Boettcher, J Gołąb, W Huber, S Fröhling and T Zenz Leukemia 2016 30: 2409-2412; advance online publication, August 18, 2016; 10.1038/leu.2016.230 Full Text | | | | The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasmsM O Holmström, C H Riley, I M Svane, H C Hasselbalch and M H Andersen Leukemia 2016 30: 2413-2416; advance online publication, August 18, 2016; 10.1038/leu.2016.233 Full Text | | | | Toll-like receptor signaling-deficient mice are easy mobilizers: evidence that TLR signaling prevents mobilization of hematopoietic stem/progenitor cells in HO-1-dependent manner OPENM Adamiak, A Abdelbaset-Ismail, M Kucia, J Ratajczak and M Z Ratajczak Leukemia 2016 30: 2416-2419; advance online publication, August 18, 2016; 10.1038/leu.2016.236 Full Text | | | | Evidence of shared epitopic reactivity among independent B-cell clones in chronic lymphocytic leukemia patients OPENS Mimmi, E Vecchio, E Iaccino, M Rossi, A Lupia, F Albano, F Chiurazzi, G Fiume, A Pisano, S Ceglia, M Pontoriero, G Golino, P Tassone, I Quinto, G Scala and C Palmieri Leukemia 2016 30: 2419-2422; advance online publication, August 29, 2016; 10.1038/leu.2016.245 Full Text | | | | Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndromeE J Duncavage, J O'Brien, K Vij, C A Miller, G S Chang, J Shao, M A Jacoby, S Heath, M R Janke, K Elliott, R S Fulton, C Fronick, M O'Laughlin, P Westervelt, T J Ley, R K Wilson and M J Walter Leukemia 2016 30: 2422-2426; advance online publication, August 30, 2016; 10.1038/leu.2016.247 Full Text | | | | Allogeneic hematopoietic cell transplantation with double alkylating agents containing reduced-intensity conditioning for patients ≥60 years with advanced AML/MDSH Bertz, M Lübbert, K Ohneberg, R Zeiser, R Wäsch, R Marks and J Finke Leukemia 2016 30: 2426-2429; advance online publication, August 30, 2016; 10.1038/leu.2016.248 Full Text | | Corrigendum | Top | | Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemiaV Madan, P Shyamsunder, L Han, A Mayakonda, Y Nagata, J Sundaresan, D Kanojia, K Yoshida, S Ganesan, N Hattori, N Fulton, K T Tan, T Alpermann, M C Kuo, S Rostami, J Matthews, M Sanada, L-Z Liu, Y Shiraishi, S Miyano, E Chendamarai, H A Hou, G Malnassy, T Ma, M Garg, L W Ding, Q Y Sun, W Chien, T Ikezoe, M Lill, A Biondi, R A Larson, B L Powell, M Lübbert, W J Chng, H F Tien, M Heuser, A Ganser, M Koren-Michowitz, S M Kornblau, H M Kantarjian, D Nowak, W K Hofmann, H Yang, W Stock, A Ghavamzadeh, K Alimoghaddam, T Haferlach, S Ogawa, L Y Shih, V Mathews and H P Koeffler Leukemia 2016 30: 2430; advance online publication, October 7, 2016; 10.1038/leu.2016.237 Full Text | | | | | | | | | | | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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