Wednesday, October 19, 2016

Molecular Psychiatry - Table of Contents alert Volume 21 Issue 11

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Molecular Psychiatry

TABLE OF CONTENTS

Volume 21, Issue 11 (November 2016)

In this issue
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News and Commentary
Reviews
Original Articles
Corrigenda
Erratum

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A new open access journal dedicated to publishing the most important scientific advances in all aspects of genomics and its application in the practice of medicine. Part of the Nature Partner Journals series, the journal is published in partnership with the Center of Excellence in Genomic Medicine Research. 

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Misassembly of non-mutant full-length Disrupted-in-Schizophrenia 1 protein is induced by dopamine in vitro and in vivo

V Bader, S V Trossbach, I Prikulis, S F Godsave, P J Peters and C Korth

Mol Psychiatry 2016 21: 1487; 10.1038/mp.2016.190

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News and Commentary

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DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1

M Niwa, T Cash-Padgett, K-I Kubo, A Saito, K Ishii, A Sumitomo, Y Taniguchi, K Ishizuka, H Jaaro-Peled, T Tomoda, K Nakajima, A Sawa and A Kamiya

Mol Psychiatry 2016 21: 1488-1489; advance online publication, September 6, 2016; 10.1038/mp.2016.154

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Reviews

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Dissecting bipolar disorder complexity through epigenomic approach OPEN

B Ludwig and Y Dwivedi

Mol Psychiatry 2016 21: 1490-1498; advance online publication, August 2, 2016; 10.1038/mp.2016.123

Abstract | Full Text | PDF

The significance of selegiline/(−)-deprenyl after 50 years in research and therapy (1965–2015)

I Miklya

Mol Psychiatry 2016 21: 1499-1503; advance online publication, August 2, 2016; 10.1038/mp.2016.127

Abstract | Full Text | PDF

Original Articles

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Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis OPEN

N Yoshimi, T Futamura, S E Bergen, Y Iwayama, T Ishima, C Sellgren, C J Ekman, J Jakobsson, E Pålsson, K Kakumoto, Y Ohgi, T Yoshikawa, M Landén and K Hashimoto

Mol Psychiatry 2016 21: 1504-1510; advance online publication, January 19, 2016; 10.1038/mp.2015.217

Abstract | Full Text | PDF

Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis

S Georgin-Lavialle, D S Moura, A Salvador, J-C Chauvet-Gelinier, J-M Launay, G Damaj, F Côté, E Soucié, M-O Chandesris, S Barète, C Grandpeix-Guyodo, C Bachmeyer, M-A Alyanakian, A Aouba, O Lortholary, P Dubreuil, J-R Teyssier, B Trojak, E Haffen, P Vandel, B Bonin, the French Mast Cell Study Group, O Hermine and R Gaillard

Mol Psychiatry 2016 21: 1511-1516; advance online publication, January 26, 2016; 10.1038/mp.2015.216

Abstract | Full Text | PDF

KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia

G V Carr, J Chen, F Yang, M Ren, P Yuan, Q Tian, A Bebensee, G Y Zhang, J Du, P Glineburg, R Xun, O Akhile, D Akuma, J Pickel, J C Barrow, F Papaleo and D R Weinberger

Mol Psychiatry 2016 21: 1517-1526; advance online publication, February 9, 2016; 10.1038/mp.2015.219

Abstract | Full Text | PDF

In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy

I Loryan, E Melander, M Svensson, M Payan, F König, B Jansson and M Hammarlund-Udenaes

Mol Psychiatry 2016 21: 1527-1536; advance online publication, January 26, 2016; 10.1038/mp.2015.229

Abstract | Full Text | PDF

Metformin treatment of antipsychotic-induced dyslipidemia: an analysis of two randomized, placebo-controlled trials OPEN

R-R Wu, F-Y Zhang, K-M Gao, J-J Ou, P Shao, H Jin, W-B Guo, P K Chan and J-P Zhao

Mol Psychiatry 2016 21: 1537-1544; advance online publication, January 26, 2016; 10.1038/mp.2015.221

Abstract | Full Text | PDF

Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala

D De Bundel, C Zussy, J Espallergues, C R Gerfen, J-A Girault and E Valjent

Mol Psychiatry 2016 21: 1545-1553; advance online publication, January 19, 2016; 10.1038/mp.2015.210

Abstract | Full Text | PDF

Midbrain functional connectivity and ventral striatal dopamine D2-type receptors: link to impulsivity in methamphetamine users

M Kohno, K Okita, A M Morales, C L Robertson, A C Dean, D G Ghahremani, F W Sabb, R A Rawson, M A Mandelkern, R M Bilder and E D London

Mol Psychiatry 2016 21: 1554-1560; advance online publication, February 2, 2016; 10.1038/mp.2015.223

Abstract | Full Text | PDF

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits OPEN

S V Trossbach, V Bader, L Hecher, M E Pum, S T Masoud, I Prikulis, S Schäble, M A de Souza Silva, P Su, B Boulat, C Chwiesko, G Poschmann, K Stühler, K M Lohr, K A Stout, A Oskamp, S F Godsave, A Müller-Schiffmann, T Bilzer, H Steiner, P J Peters, A Bauer, M Sauvage, A J Ramsey, G W Miller, F Liu, P Seeman, N J Brandon, J P Huston and C Korth

Mol Psychiatry 2016 21: 1561-1572; advance online publication, January 12, 2016; 10.1038/mp.2015.194

Abstract | Full Text | PDF

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology

C Bardy, M van den Hurk, B Kakaradov, J A Erwin, B N Jaeger, R V Hernandez, T Eames, A A Paucar, M Gorris, C Marchand, R Jappelli, J Barron, A K Bryant, M Kellogg, R S Lasken, B P F Rutten, H W M Steinbusch, G W Yeo and F H Gage

Mol Psychiatry 2016 21: 1573-1588; advance online publication, October 4, 2016; 10.1038/mp.2016.158

Abstract | Full Text | PDF

Separating the wheat from the chaff: systematic identification of functionally relevant noncoding variants in ADHD

J H S Tong, Z Hawi, C Dark, T D R Cummins, B P Johnson, D P Newman, R Lau, A Vance, H S Heussler, N Matthews, M A Bellgrove and K C Pang

Mol Psychiatry 2016 21: 1589-1598; advance online publication, April 26, 2016; 10.1038/mp.2016.2

Abstract | Full Text | PDF

Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features OPEN

M Heidari, D M Johnstone, B Bassett, R M Graham, A C G Chua, M J House, J F Collingwood, C Bettencourt, H Houlden, M Ryten, J K Olynyk, D Trinder and E A Milward for the UK Brain Expression Consortium (UKBEC)

Mol Psychiatry 2016 21: 1599-1607; advance online publication, January 5, 2016; 10.1038/mp.2015.192

Abstract | Full Text | PDF

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG, and PDCL3

C Herold, B V Hooli, K Mullin, T Liu, J T Roehr, M Mattheisen, A R Parrado, L Bertram, C Lange and R E Tanzi

Mol Psychiatry 2016 21: 1608-1612; advance online publication, February 2, 2016; 10.1038/mp.2015.218

Abstract | Full Text | PDF

Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1 OPEN

N Fujitsuka, A Asakawa, A Morinaga, M S Amitani, H Amitani, G Katsuura, Y Sawada, Y Sudo, Y Uezono, E Mochiki, I Sakata, T Sakai, K Hanazaki, T Yada, K Yakabi, E Sakuma, T Ueki, A Niijima, K Nakagawa, N Okubo, H Takeda, M Asaka and A Inui

Mol Psychiatry 2016 21: 1613-1623; advance online publication, February 2, 2016; 10.1038/mp.2015.220

Abstract | Full Text | PDF

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112151) and 24 GWAS consortia OPEN

S P Hagenaars, S E Harris, G Davies, W D Hill, D C M Liewald, S J Ritchie, R E Marioni, C Fawns-Ritchie, B Cullen, R Malik, METASTROKE Consortium, International Consortium for Blood Pressure GWAS, SpiroMeta Consortium, CHARGE Consortium Pulmonary Group, CHARGE Consortium Aging and Longevity Group, B B Worrall, C L M Sudlow, J M Wardlaw, J Gallacher, J Pell, A M McIntosh, D J Smith, C R Gale and I J Deary

Mol Psychiatry 2016 21: 1624-1632; advance online publication, January 26, 2016; 10.1038/mp.2015.225

Abstract | Full Text | PDF

Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise OPEN

C Suo, M F Singh, N Gates, W Wen, P Sachdev, H Brodaty, N Saigal, G C Wilson, J Meiklejohn, N Singh, B T Baune, M Baker, N Foroughi, Y Wang, Y Mavros, A Lampit, I Leung and M J Valenzuela

Mol Psychiatry 2016 21: 1633-1642; advance online publication, March 22, 2016; 10.1038/mp.2016.19

Abstract | Full Text | PDF

Corrigenda

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Attention-deficit hyperactivity disorder in adults: a systematic review and meta-analysis of genetic, pharmacogenetic and biochemical studies OPEN

C Bonvicini, S V Faraone and C Scassellati

Mol Psychiatry 2016 21: 1643; advance online publication, August 9, 2016; 10.1038/mp.2016.128

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Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci OPEN

D J Smith, V Escott-Price, G Davies, M E S Bailey, L Colodro-Conde, J Ward, A Vedernikov, R Marioni, B Cullen, D Lyall, S P Hagenaars, D C M Liewald, M Luciano, C R Gale, S J Ritchie, C Hayward, B Nicholl, B Bulik-Sullivan, M Adams, B Couvy-Duchesne, N Graham, D Mackay, J Evans, B H Smith, D J Porteous, S E Medland, N G Martin, P Holmans, A M McIntosh, J P Pell, I J Deary and M C O'Donovan

Mol Psychiatry 2016 21: 1644; advance online publication, September 13, 2016; 10.1038/mp.2016.177

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Erratum

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Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise

C Suo, M F Singh, N Gates, W Wen, P Sachdev, H Brodaty, N Saigal, G C Wilson, J Meiklejohn, N Singh, B T Baune, M Baker, N Foroughi, Y Wang, Y Mavros, A Lampit, I Leung and M J Valenzuela

Mol Psychiatry 2016 21: 1645; advance online publication, April 19, 2016; 10.1038/mp.2016.57

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