TABLE OF CONTENTS
|  |  |  | Volume 21, Issue 11 (November 2016) |  | In this issue Image News and Commentary Reviews Original Articles Corrigenda Erratum
Also new    AOP
| |  |  |  | | Advertisement |  | A new open access journal dedicated to publishing the most important scientific advances in all aspects of genomics and its application in the practice of medicine. Part of the Nature Partner Journals series, the journal is published in partnership with the Center of Excellence in Genomic Medicine Research.
Open for submissions |  | | |  |  | Image | Top |  | Misassembly of non-mutant full-length Disrupted-in-Schizophrenia 1 protein is induced by dopamine in vitro and in vivoV Bader, S V Trossbach, I Prikulis, S F Godsave, P J Peters and C Korth Mol Psychiatry 2016 21: 1487; 10.1038/mp.2016.190 Full Text | PDF |  | News and Commentary | Top |  | DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1M Niwa, T Cash-Padgett, K-I Kubo, A Saito, K Ishii, A Sumitomo, Y Taniguchi, K Ishizuka, H Jaaro-Peled, T Tomoda, K Nakajima, A Sawa and A Kamiya Mol Psychiatry 2016 21: 1488-1489; advance online publication, September 6, 2016; 10.1038/mp.2016.154 Full Text | PDF |  | Reviews | Top |  | Dissecting bipolar disorder complexity through epigenomic approach OPENB Ludwig and Y Dwivedi Mol Psychiatry 2016 21: 1490-1498; advance online publication, August 2, 2016; 10.1038/mp.2016.123 Abstract | Full Text | PDF |  |  |  | The significance of selegiline/(−)-deprenyl after 50 years in research and therapy (1965–2015)I Miklya Mol Psychiatry 2016 21: 1499-1503; advance online publication, August 2, 2016; 10.1038/mp.2016.127 Abstract | Full Text | PDF |  | Original Articles | Top |  | Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis OPENN Yoshimi, T Futamura, S E Bergen, Y Iwayama, T Ishima, C Sellgren, C J Ekman, J Jakobsson, E Pålsson, K Kakumoto, Y Ohgi, T Yoshikawa, M Landén and K Hashimoto Mol Psychiatry 2016 21: 1504-1510; advance online publication, January 19, 2016; 10.1038/mp.2015.217 Abstract | Full Text | PDF |  |  |  | Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosisS Georgin-Lavialle, D S Moura, A Salvador, J-C Chauvet-Gelinier, J-M Launay, G Damaj, F Côté, E Soucié, M-O Chandesris, S Barète, C Grandpeix-Guyodo, C Bachmeyer, M-A Alyanakian, A Aouba, O Lortholary, P Dubreuil, J-R Teyssier, B Trojak, E Haffen, P Vandel, B Bonin, the French Mast Cell Study Group, O Hermine and R Gaillard Mol Psychiatry 2016 21: 1511-1516; advance online publication, January 26, 2016; 10.1038/mp.2015.216 Abstract | Full Text | PDF |  |  |  | KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophreniaG V Carr, J Chen, F Yang, M Ren, P Yuan, Q Tian, A Bebensee, G Y Zhang, J Du, P Glineburg, R Xun, O Akhile, D Akuma, J Pickel, J C Barrow, F Papaleo and D R Weinberger Mol Psychiatry 2016 21: 1517-1526; advance online publication, February 9, 2016; 10.1038/mp.2015.219 Abstract | Full Text | PDF |  |  |  | In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancyI Loryan, E Melander, M Svensson, M Payan, F König, B Jansson and M Hammarlund-Udenaes Mol Psychiatry 2016 21: 1527-1536; advance online publication, January 26, 2016; 10.1038/mp.2015.229 Abstract | Full Text | PDF |  |  |  | Metformin treatment of antipsychotic-induced dyslipidemia: an analysis of two randomized, placebo-controlled trials OPENR-R Wu, F-Y Zhang, K-M Gao, J-J Ou, P Shao, H Jin, W-B Guo, P K Chan and J-P Zhao Mol Psychiatry 2016 21: 1537-1544; advance online publication, January 26, 2016; 10.1038/mp.2015.221 Abstract | Full Text | PDF |  |  |  | Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdalaD De Bundel, C Zussy, J Espallergues, C R Gerfen, J-A Girault and E Valjent Mol Psychiatry 2016 21: 1545-1553; advance online publication, January 19, 2016; 10.1038/mp.2015.210 Abstract | Full Text | PDF |  |  |  | Midbrain functional connectivity and ventral striatal dopamine D2-type receptors: link to impulsivity in methamphetamine usersM Kohno, K Okita, A M Morales, C L Robertson, A C Dean, D G Ghahremani, F W Sabb, R A Rawson, M A Mandelkern, R M Bilder and E D London Mol Psychiatry 2016 21: 1554-1560; advance online publication, February 2, 2016; 10.1038/mp.2015.223 Abstract | Full Text | PDF |  |  |  | Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits OPENS V Trossbach, V Bader, L Hecher, M E Pum, S T Masoud, I Prikulis, S Schäble, M A de Souza Silva, P Su, B Boulat, C Chwiesko, G Poschmann, K Stühler, K M Lohr, K A Stout, A Oskamp, S F Godsave, A Müller-Schiffmann, T Bilzer, H Steiner, P J Peters, A Bauer, M Sauvage, A J Ramsey, G W Miller, F Liu, P Seeman, N J Brandon, J P Huston and C Korth Mol Psychiatry 2016 21: 1561-1572; advance online publication, January 12, 2016; 10.1038/mp.2015.194 Abstract | Full Text | PDF |  |  |  | Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiologyC Bardy, M van den Hurk, B Kakaradov, J A Erwin, B N Jaeger, R V Hernandez, T Eames, A A Paucar, M Gorris, C Marchand, R Jappelli, J Barron, A K Bryant, M Kellogg, R S Lasken, B P F Rutten, H W M Steinbusch, G W Yeo and F H Gage Mol Psychiatry 2016 21: 1573-1588; advance online publication, October 4, 2016; 10.1038/mp.2016.158 Abstract | Full Text | PDF |  |  |  | Separating the wheat from the chaff: systematic identification of functionally relevant noncoding variants in ADHDJ H S Tong, Z Hawi, C Dark, T D R Cummins, B P Johnson, D P Newman, R Lau, A Vance, H S Heussler, N Matthews, M A Bellgrove and K C Pang Mol Psychiatry 2016 21: 1589-1598; advance online publication, April 26, 2016; 10.1038/mp.2016.2 Abstract | Full Text | PDF |  |  |  | Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features OPENM Heidari, D M Johnstone, B Bassett, R M Graham, A C G Chua, M J House, J F Collingwood, C Bettencourt, H Houlden, M Ryten, J K Olynyk, D Trinder and E A Milward for the UK Brain Expression Consortium (UKBEC) Mol Psychiatry 2016 21: 1599-1607; advance online publication, January 5, 2016; 10.1038/mp.2015.192 Abstract | Full Text | PDF |  |  |  | Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG, and PDCL3C Herold, B V Hooli, K Mullin, T Liu, J T Roehr, M Mattheisen, A R Parrado, L Bertram, C Lange and R E Tanzi Mol Psychiatry 2016 21: 1608-1612; advance online publication, February 2, 2016; 10.1038/mp.2015.218 Abstract | Full Text | PDF |  |  |  | Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1 OPENN Fujitsuka, A Asakawa, A Morinaga, M S Amitani, H Amitani, G Katsuura, Y Sawada, Y Sudo, Y Uezono, E Mochiki, I Sakata, T Sakai, K Hanazaki, T Yada, K Yakabi, E Sakuma, T Ueki, A Niijima, K Nakagawa, N Okubo, H Takeda, M Asaka and A Inui Mol Psychiatry 2016 21: 1613-1623; advance online publication, February 2, 2016; 10.1038/mp.2015.220 Abstract | Full Text | PDF |  |  |  | Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia OPENS P Hagenaars, S E Harris, G Davies, W D Hill, D C M Liewald, S J Ritchie, R E Marioni, C Fawns-Ritchie, B Cullen, R Malik, METASTROKE Consortium, International Consortium for Blood Pressure GWAS, SpiroMeta Consortium, CHARGE Consortium Pulmonary Group, CHARGE Consortium Aging and Longevity Group, B B Worrall, C L M Sudlow, J M Wardlaw, J Gallacher, J Pell, A M McIntosh, D J Smith, C R Gale and I J Deary Mol Psychiatry 2016 21: 1624-1632; advance online publication, January 26, 2016; 10.1038/mp.2015.225 Abstract | Full Text | PDF |  |  |  | Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise OPENC Suo, M F Singh, N Gates, W Wen, P Sachdev, H Brodaty, N Saigal, G C Wilson, J Meiklejohn, N Singh, B T Baune, M Baker, N Foroughi, Y Wang, Y Mavros, A Lampit, I Leung and M J Valenzuela Mol Psychiatry 2016 21: 1633-1642; advance online publication, March 22, 2016; 10.1038/mp.2016.19 Abstract | Full Text | PDF |  | Corrigenda | Top |  | Attention-deficit hyperactivity disorder in adults: a systematic review and meta-analysis of genetic, pharmacogenetic and biochemical studies OPENC Bonvicini, S V Faraone and C Scassellati Mol Psychiatry 2016 21: 1643; advance online publication, August 9, 2016; 10.1038/mp.2016.128 Full Text | PDF |  |  |  | Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci OPEND J Smith, V Escott-Price, G Davies, M E S Bailey, L Colodro-Conde, J Ward, A Vedernikov, R Marioni, B Cullen, D Lyall, S P Hagenaars, D C M Liewald, M Luciano, C R Gale, S J Ritchie, C Hayward, B Nicholl, B Bulik-Sullivan, M Adams, B Couvy-Duchesne, N Graham, D Mackay, J Evans, B H Smith, D J Porteous, S E Medland, N G Martin, P Holmans, A M McIntosh, J P Pell, I J Deary and M C O'Donovan Mol Psychiatry 2016 21: 1644; advance online publication, September 13, 2016; 10.1038/mp.2016.177 Full Text | PDF |  | Erratum | Top |  | Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exerciseC Suo, M F Singh, N Gates, W Wen, P Sachdev, H Brodaty, N Saigal, G C Wilson, J Meiklejohn, N Singh, B T Baune, M Baker, N Foroughi, Y Wang, Y Mavros, A Lampit, I Leung and M J Valenzuela Mol Psychiatry 2016 21: 1645; advance online publication, April 19, 2016; 10.1038/mp.2016.57 Full Text | PDF |  |  |  |  |  |  |  |  |  |  | Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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