Molecular Therapy - Table of Contents alert Volume 24 Issue 3

If you are unable to see the message below, click here to view.

TABLE OF CONTENTS Volume 24, Issue 3 (March 2016) In this issue Editorial In This Issue Research Highlights Commentaries Review Original Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Editorial Top A New Induction to the Gene and Cell Therapy Hall Of Fame: Genome Editing Michel Sadelain Mol Ther 2016 24: 407-408; 10.1038/mt.2016.25 Full Text In This Issue Top In This Issue Mol Ther 2016 24: 410; 10.1038/mt.2016.26 Full Text Research Highlights Top Research Highlights Mol Ther 2016 24: 411; 10.1038/mt.2016.27 Full Text Commentaries Top A Perspective on the State of Genome Editing Dana Carroll Mol Ther 2016 24: 412-413; 10.1038/mt.2016.28 Full Text CRISPR/Cas9 Flexes Its Muscles: In Vivo Somatic Gene Editing for Muscular Dystrophy Thierry VandenDriessche and Marinee K Chuah Mol Ther 2016 24: 414-416; 10.1038/mt.2016.29 Full Text A CRISPR Approach for Reactivating Latent HIV-1 Angel Lin and Zachary Klase Mol Ther 2016 24: 416-418; 10.1038/mt.2016.30 Full Text Patent Law and Genome Engineering: A Short Guide to a Rapidly Changing Landscape Ross Cloney Mol Ther 2016 24: 419-421; 10.1038/mt.2016.31 Full Text Review Top Salient Features of Endonuclease Platforms for Therapeutic Genome Editing Michael T Certo and Richard A Morgan Mol Ther 2016 24: 422-429; advance online publication, January 22, 2016; 10.1038/mt.2016.21 Abstract | Full Text Genome-editing Technologies for Gene and Cell TherapyMTOPEN Morgan L Maeder and Charles A Gersbach Mol Ther 2016 24: 430-446; advance online publication, January 12, 2016; 10.1038/mt.2016.10 Abstract | Full Text Engineered Viruses as Genome Editing DevicesMTOPEN Xiaoyu Chen and Manuel A F V Gonçalves Mol Ther 2016 24: 447-457; advance online publication, September 4, 2015; 10.1038/mt.2015.164 Abstract | Full Text Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications Thomas Gaj, Benjamin E Epstein and David V Schaffer Mol Ther 2016 24: 458-464; advance online publication, September 16, 2015; 10.1038/mt.2015.151 Abstract | Full Text Current Progress in Therapeutic Gene Editing for Monogenic Diseases Versha Prakash, Marc Moore and Rafael J Yáñez-Muñoz Mol Ther 2016 24: 465-474; advance online publication, January 14, 2016; 10.1038/mt.2016.5 Abstract | Full Text Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingMTOPEN Ciaran M Lee, Thomas J Cradick, Eli J Fine and Gang Bao Mol Ther 2016 24: 475-487; advance online publication, January 11, 2016; 10.1038/mt.2016.1 Abstract | Full Text Original Articles Top Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator ComplexMTOPEN Sheena M Saayman, Daniel C Lazar, Tristan A Scott, Jonathan R Hart, Mayumi Takahashi, John C Burnett, Vicente Planelles, Kevin V Morris and Marc S Weinberg Mol Ther 2016 24: 488-498; advance online publication, November 19, 2015; 10.1038/mt.2015.202 Abstract | Full Text CRISPR-mediated Activation of Latent HIV-1 Expression Prajit Limsirichai, Thomas Gaj and David V Schaffer Mol Ther 2016 24: 499-507; advance online publication, November 26, 2015; 10.1038/mt.2015.213 Abstract | Full Text Specific Reactivation of Latent HIV-1 by dCas9-SunTag-VP64-mediated Guide RNA Targeting the HIV-1 Promoter Haiyan Ji, Zhengtao Jiang, Panpan Lu, Li Ma, Chuan Li, Hanyu Pan, Zheng Fu, Xiying Qu, Pengfei Wang, Junxiao Deng, Xinyi Yang, Jianhua Wang and Huanzhang Zhu Mol Ther 2016 24: 508-521; advance online publication, January 18, 2016; 10.1038/mt.2016.7 Abstract | Full Text CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus EscapeMTOPEN Gang Wang, Na Zhao, Ben Berkhout and Atze T Das Mol Ther 2016 24: 522-526; advance online publication, January 22, 2016; 10.1038/mt.2016.24 Abstract | Full Text CRISPR/dCas9-mediated Transcriptional Inhibition Ameliorates the Epigenetic Dysregulation at D4Z4 and Represses DUX4-fl in FSH Muscular Dystrophy Charis L Himeda, Takako I Jones and Peter L Jones Mol Ther 2016 24: 527-535; advance online publication, November 3, 2015; 10.1038/mt.2015.200 Abstract | Full Text Re-expression of Selected Epigenetically Silenced Candidate Tumor Suppressor Genes in Cervical Cancer by TET2-directed Demethylation Christian Huisman, Monique G P van der Wijst, Matthijs Schokker, Pilar Blancafort, Martijn M Terpstra, Klaas Kok, Ate G J van der Zee, Ed Schuuring, G Bea A Wisman and Marianne G Rots Mol Ther 2016 24: 536-547; advance online publication, December 21, 2015; 10.1038/mt.2015.226 Abstract | Full Text Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse BrainMTOPEN Barbara J Bailus, Benjamin Pyles, Michelle M McAlister, Henriette O'Geen, Sarah H Lockwood, Alexa N Adams, Jennifer Trang T Nguyen, Abigail Yu, Robert F Berman and David J Segal Mol Ther 2016 24: 548-555; advance online publication, January 4, 2016; 10.1038/mt.2015.236 Abstract | Full Text In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis PigmentosaMTOPEN Benjamin Bakondi, Wenjian Lv, Bin Lu, Melissa K Jones, Yuchun Tsai, Kevin J Kim, Rachelle Levy, Aslam Abbasi Akhtar, Joshua J Breunig, Clive N Svendsen and Shaomei Wang Mol Ther 2016 24: 556-563; advance online publication, December 15, 2015; 10.1038/mt.2015.220 Abstract | Full Text CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice Li Xu, Ki Ho Park, Lixia Zhao, Jing Xu, Mona El Refaey, Yandi Gao, Hua Zhu, Jianjie Ma and Renzhi Han Mol Ther 2016 24: 564-569; advance online publication, October 9, 2015; 10.1038/mt.2015.192 Abstract | Full Text Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases Mark J Osborn, Beau R Webber, Friederike Knipping, Cara-lin Lonetree, Nicole Tennis, Anthony P DeFeo, Amber N McElroy, Colby G Starker, Catherine Lee, Sarah Merkel, Troy C Lund, Karen S Kelly-Spratt, Michael C Jensen, Daniel F Voytas, Christof von Kalle, Manfred Schmidt, Richard Gabriel, Keli L Hippen, Jeffrey S Miller, Andrew M Scharenberg, Jakub Tolar and Bruce R Blazar Mol Ther 2016 24: 570-581; advance online publication, October 27, 2015; 10.1038/mt.2015.197 Abstract | Full Text Silent IL2RG Gene Editing in Human Pluripotent Stem Cells Li B Li, Chao Ma, Geneve Awong, Marion Kennedy, German Gornalusse, Gordon Keller, Dan S Kaufman and David W Russell Mol Ther 2016 24: 582-591; advance online publication, October 7, 2015; 10.1038/mt.2015.190 Abstract | Full Text Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4+ T CellsMTOPEN Andreas Gogol-Döring, Ismahen Ammar, Saumyashree Gupta, Mario Bunse, Csaba Miskey, Wei Chen, Wolfgang Uckert, Thomas F Schulz, Zsuzsanna Izsvák and Zoltán Ivics Mol Ther 2016 24: 592-606; advance online publication, January 12, 2016; 10.1038/mt.2016.11 Abstract | Full Text Multidimensional Genome-wide Analyses Show Accurate FVIII Integration by ZFN in Primary Human CellsMTOPEN Jaichandran Sivalingam, Dimitar Kenanov, Hao Han, Ajit Johnson Nirmal, Wai Har Ng, Sze Sing Lee, Jeyakumar Masilamani, Toan Thang Phan, Sebastian Maurer-Stroh and Oi Lian Kon Mol Ther 2016 24: 607-619; advance online publication, December 22, 2015; 10.1038/mt.2015.223 Abstract | Full Text Sleeping Beauty Transposon Vectors in Liver-directed Gene Delivery of LDLR and VLDLR for Gene Therapy of Familial Hypercholesterolemia Tytteli A K Turunen, Jere Kurkipuro, Tommi Heikura, Taina Vuorio, Elisa Hytönen, Zsuzsanna Izsvák and Seppo Ylä-Herttuala Mol Ther 2016 24: 620-635; advance online publication, December 16, 2015; 10.1038/mt.2015.221 Abstract | Full Text Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome Maximilian Müller, Ciaran M Lee, Giedrius Gasiunas, Timothy H Davis, Thomas J Cradick, Virginijus Siksnys, Gang Bao, Toni Cathomen and Claudio Mussolino Mol Ther 2016 24: 636-644; advance online publication, December 14, 2015; 10.1038/mt.2015.218 Abstract | Full Text The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian CellsMTOPEN Ciaran M Lee, Thomas J Cradick and Gang Bao Mol Ther 2016 24: 645-654; advance online publication, January 19, 2016; 10.1038/mt.2016.8 Abstract | Full Text Advertisement Molecular Therapy - Nucleic Acids is an online-only, open access journal publishing high quality basic, translational, and clinical research and cutting-edge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies. The journal has an Impact Factor of 4.512. Explore the benefits of submitting your next research article. Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group |One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2016 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.