Nature Reviews Neuroscience contents October 2015 Volume 16 Number 10 pp 575-642

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TABLE OF CONTENTS
October 2015 Volume 16 Number 10		Advertisement
Impact Factor 31.427 *	In this issue Research Highlights Reviews Perspectives Correspondence Also this month Article series: The endocannabinoid system  Featured article: Endocannabinoid signalling in reward and addiction Loren H. Parsons & Yasmin L. Hurd	Reach optimal transfection efficiency on primary neurons and neural cells with NeuroMag NeuroMag is a unique magnetic-assisted transfection reagent dedicated to transfect nervous system cells with high efficiency from DIV 1 to DIV 21. Hippocampal, cortical, motor neurons, neural stem cells, dopaminergic... have been successfully transfected. Click here to learn more about NeuroMag reagent.  www.ozbiosciences.com
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RESEARCH HIGHLIGHTS Top Spatial processing: Mapping function p575 | doi:10.1038/nrn4029 Studies reveal a gradient in the functional properties of neurons along the transverse axis of hippocampal CA3 and their likely contribution to pattern separation and pattern completion. PDF Neurodegenerative disease: Downsizing neurons p576 | doi:10.1038/nrn4027 Neuronal atrophy early in a mouse model of spinal cerebellar ataxia 1 may represent an adaptive mechanism that restores the density of potassium channels in Purkinje neurons, thus normalizing membrane polarization and firing. PDF Learning and memory: Conditions for fear p576 | doi:10.1038/nrn4030 State-dependent fear conditioning can be induced by activation of hippocampal extrasynaptic GABAA receptors and is regulated by protein kinase CβII activity and microRNA-33 signalling. PDF Neural development: A complex competition for spines p577 | doi:10.1038/nrn4024 Activity-dependent redistribution of cadherin–catenin complexes between neighbouring dendritic spines drives pruning versus maturation. PDF Neural development: Lipid guideposts p578 | doi:10.1038/nrn4035 A derivative of a glial membrane phospholipid has a crucial role in nociceptive-axon guidance in the spinal cord of chicks and mice. PDF IN BRIEF Techniques: The power of radio waves | Neuronal circuits: Fear and anxiety generalization | Learning and memory: Remembering in space and time | Neurobiology of reward: Predicting the unexpected PDF Neuroscience JOBS of the week PhD Student (F / M) in Neuroscience German Center for Neurodegenerative Deseases Assistant / Associate Professors in Neuroscience Virginia Tech (VT) Institute Assoc Scientist IV – Target Biology – Neuroscience The University of Texas MD Anderson Cancer Center More Science jobs from Neuroscience EVENT Neuroscience R&D Technologies Conference 03.12.15 Barcelona, Spain More science events from
REVIEWS		Top
Article series: The endocannabinoid system Endocannabinoid signalling in reward and addiction Loren H. Parsons & Yasmin L. Hurd p579 | doi:10.1038/nrn4004 Cannabinoid receptors and their endogenous ligands, the endocannabinoids, are widely expressed in the brain, particularly in regions that are implicated in mediating reward. In this Review, Parsons and Hurd explore the role of endocannabinoid signalling in natural and drug-induced reward, as well as in addiction. Abstract | Full Text | PDF
Dysregulation and restoration of translational homeostasis in fragile X syndrome Joel D. Richter, Gary J. Bassell & Eric Klann p595 | doi:10.1038/nrn4001 Fragile X syndrome (FXS) results from the loss of the RNA-binding protein fragile X mental retardation protein (FMRP). Here, Klann and colleagues discuss the ways in which FMRP loss disrupts mRNA translation in the brain and the outcomes of genetic and pharmacological attempts to reset translational homeostasis in FXS model mice. Abstract | Full Text | PDF
The attentive brain: insights from developmental cognitive neuroscience Dima Amso & Gaia Scerif p606 | doi:10.1038/nrn4025 Attention processes allow the selection of salient information over competing inputs. In this Review, Amso and Scerif propose a framework for visual attention development that incorporates its interactions with visual and memory systems and may guide the design of training programmes to alleviate attention disorders. Abstract | Full Text | PDF
Social cognition in schizophrenia Michael F. Green, William P. Horan & Junghee Lee p620 | doi:10.1038/nrn4005 Impairment of social cognition is an important feature of schizophrenia. Green and colleagues review the social processes that are affected in people with this disorder and consider empathy — a complex social cognitive function that involves several of these processes — in such individuals. Abstract | Full Text | PDF
PERSPECTIVES		Top
OPINION Tinnitus: perspectives from human neuroimaging Ana Belén Elgoyhen, Berthold Langguth, Dirk De Ridder & Sven Vanneste p632 | doi:10.1038/nrn4003 The causes and neurological mechanisms of tinnitus remain incompletely understood. In this Opinion, Elgoyhen et al. critically assess recent neuroimaging studies of people with tinnitus that implicate structural and functional changes among auditory and non-auditory areas and networks, and suggest ways to improve future research into the disorder. Abstract | Full Text | PDF | Supplementary information
CORRESPONDENCE		Top
Neuronal circuits for fear and anxiety — the missing link Richard Apps & Piergiorgio Strata p642 | doi:10.1038/nrn4028 Full Text | PDF
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*2014 Journal Citation Report (Thomson Reuters, 2015)

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