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Molecular Therapy - Nucleic Acids is an online-only, open access journal publishing high quality basic, translational, and clinical research and cutting-edge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies.
Explore the benefits of submitting your next research article. | | | | | | Editorial | Top | | Molecular Therapy Special Issue on Gene Editing Technologies and ApplicationsRobert Frederickson and Seppo Ylä-Herttuala Mol Ther 2015 23: 1279; 10.1038/mt.2015.80 Full Text | | In This Issue | Top | | In This IssueMol Ther 2015 23: 1280; 10.1038/mt.2015.117 Full Text | | Research Highlights | Top | | Research HighlightsMol Ther 2015 23: 1281; 10.1038/mt.2015.116 Full Text | | Commentaries | Top | | ASGCT and JSGT Joint Position Statement on Human Genomic EditingTheodore Friedmann, Erica C Jonlin, Nancy M P King, Bruce E Torbett, Nelson A Wivel, Yasufumi Kaneda and Michel Sadelain Mol Ther 2015 23: 1282; 10.1038/mt.2015.118 Full Text | | | | From Mesoderm to Mesodermatology: Bone Marrow Mesenchymal Cells Heal Skin WoundsMarketa Tolarova and Jakub Tolar Mol Ther 2015 23: 1283-1284; 10.1038/mt.2015.84 Full Text | | Original Articles | Top | | Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular DystrophyPam M Van Ry, Ryan D Wuebbles, Megan Key and Dean J Burkin Mol Ther 2015 23: 1285-1297; advance online publication, June 8, 2015; 10.1038/mt.2015.105 Abstract | Full Text | | | | Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman PrimatesChristian Hinderer, Peter Bell, Jean-Pierre Louboutin, Yanqing Zhu, Hongwei Yu, Gloria Lin, Ruth Choa, Brittney L Gurda, Jessica Bagel, Patricia O'Donnell, Tracey Sikora, Therese Ruane, Ping Wang, Alice F Tarantal, Margret L Casal, Mark E Haskins and James M Wilson Mol Ther 2015 23: 1298-1307; advance online publication, May 29, 2015; 10.1038/mt.2015.99 Abstract | Full Text | | | | CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis PigmentosaDaniel M Lipinski, Alun R Barnard, Mandeep S Singh, Chris Martin, Edward J Lee, Wayne I L Davies and Robert E MacLaren Mol Ther 2015 23: 1308-1319; advance online publication, April 21, 2015; 10.1038/mt.2015.68 Abstract | Full Text | | | | S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 DysfunctionJulia Ritterhoff, Mirko Völkers, Andreas Seitz, Kristin Spaich, Erhe Gao, Karsten Peppel, Sven T Pleger, Wolfram H Zimmermann, Oliver Friedrich, Rainer H A Fink, Walter J Koch, Hugo A Katus and Patrick Most Mol Ther 2015 23: 1320-1330; advance online publication, May 25, 2015; 10.1038/mt.2015.93 Abstract | Full Text | | | | Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix–related Genes in a Rat Model of OsteoarthritisMTOPENLinghui Dai, Xin Zhang, Xiaoqing Hu, Qiang Liu, Zhentao Man, Hongjie Huang, Qingyang Meng, Chunyan Zhou and Yingfang Ao Mol Ther 2015 23: 1331-1340; advance online publication, April 29, 2015; 10.1038/mt.2015.61 Abstract | Full Text | | | | Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx MiceNgoc B Lu-Nguyen, Susan A Jarmin, Amer F Saleh, Linda Popplewell, Michael J Gait and George Dickson Mol Ther 2015 23: 1341-1348; advance online publication, May 11, 2015; 10.1038/mt.2015.88 Abstract | Full Text | | | | MiR-26a Rescues Bone Regeneration Deficiency of Mesenchymal Stem Cells Derived From Osteoporotic MiceYan Li, Longkun Fan, Jiang Hu, Leilei Zhang, Li Liao, Shiyu Liu, Dan Wu, Ping Yang, Lijuan Shen, Jihua Chen and Yan Jin Mol Ther 2015 23: 1349-1357; advance online publication, June 8, 2015; 10.1038/mt.2015.101 Abstract | Full Text | | | | HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem CellsAnjie Zhen, Masakazu Kamata, Valerie Rezek, Jonathan Rick, Bernard Levin, Saro Kasparian, Irvin SY Chen, Otto O Yang, Jerome A Zack and Scott G Kitchen Mol Ther 2015 23: 1358-1367; advance online publication, June 8, 2015; 10.1038/mt.2015.102 Abstract | Full Text | | | | High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis BullosaTobias Kühl, Markus Mezger, Ingrid Hausser, Rupert Handgretinger, Leena Bruckner-Tuderman and Alexander Nyström Mol Ther 2015 23: 1368-1379; advance online publication, April 10, 2015; 10.1038/mt.2015.58 Abstract | Full Text | | | | Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic MelanomaJoal D Beane, Gary Lee, Zhili Zheng, Matthew Mendel, Daniel Abate-Daga, Mini Bharathan, Mary Black, Nimisha Gandhi, Zhiya Yu, Smita Chandran, Martin Giedlin, Dale Ando, Jeff Miller, David Paschon, Dmitry Guschin, Edward J Rebar, Andreas Reik, Michael C Holmes, Philip D Gregory, Nicholas P Restifo, Steven A Rosenberg, Richard A Morgan and Steven A Feldman Mol Ther 2015 23: 1380-1390; advance online publication, May 5, 2015; 10.1038/mt.2015.71 Abstract | Full Text | | | | mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor ImmunityGal Cafri, Adi Sharbi-Yunger, Esther Tzehoval, Zoya Alteber, Tamar Gross, Ezra Vadai, Alon Margalit, Gideon Gross and Lea Eisenbach Mol Ther 2015 23: 1391-1400; advance online publication, May 22, 2015; 10.1038/mt.2015.90 Abstract | Full Text | | | | Long-term Outcome of Extranodal NK/T Cell Lymphoma Patients Treated With Postremission Therapy Using EBV LMP1 and LMP2a-specific CTLsMTOPENSeok-Goo Cho, Nayoun Kim, Hyun-Jung Sohn, Suk Kyeong Lee, Sang Taek Oh, Hyun-Joo Lee, Hyun-Il Cho, Hyeon Woo Yim, Seung Eun Jung, Gyeongsin Park, Joo Hyun Oh, Byung-Ock Choi, Sung Won Kim, Soo Whan Kim, Nak Gyun Chung, Jong Wook Lee, Young Seon Hong and Tai-Gyu Kim Mol Ther 2015 23: 1401-1409; advance online publication, May 28, 2015; 10.1038/mt.2015.91 Abstract | Full Text | | | | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. 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