Nature Chemistry Contents April 2015 Volume 7 Number 4 pp265-360

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TABLE OF CONTENTS April 2015 Volume 7, Issue 4 Thesis Books and Arts Research Highlights Blogroll News and Views Review Articles Erratum In Your Element Subscribe   Facebook   RSS   Recommend to library   Twitter   Advertisement Tiny treasure: The future of nano-gold Watch this new Animation from Nature Nanotechnology and access Nature Outlook Gold free online for another six months. Produced with support from:  World Gold Council    Thesis Top Scents and sensibility   pp265 - 266 Michelle Francl doi:10.1038/nchem.2212 It's time to wake up and smell the chemistry, argues Michelle Francl. Books and Arts Top Weird world   pp267 - 268 Ashutosh S. Jogalekar reviews Life on the Edge: The Coming of Age of Quantum Biology by Johnjoe McFadden and Jim Al-Khalili doi:10.1038/nchem.2216 Theatre: Rekindling an old flame   pp268 - 269 doi:10.1038/nchem.2209 Research Highlights Top Asymmetric synthesis: Catalysis exposed | Biocatalysis: Harnessing haemoproteins | Nanomedicine: MOFs deliver | Natural products: Re-examining resveratrol Blogroll Top Blogroll: Tasty chemistry   p271 Joseph Meany doi:10.1038/nchem.2214 News and Views Top Origin of life: Primordial soup that cooks itself   pp273 - 274 Paul J. Bracher doi:10.1038/nchem.2219 The spontaneous syntheses of some of life's building blocks from simple precursors have previously been demonstrated in isolation. Now it has been shown that they might all emerge from just one set of ingredients. See also: Article by Patel et al. Inorganic materials: The quest for new functionality   pp274 - 275 Aron Walsh doi:10.1038/nchem.2213 Building on our understanding of the chemical bond, advances in synthetic chemistry, and large-scale computation, materials design has now become a reality. From a pool of 400 unknown compositions, 15 new compounds have been realized that adopt the predicted structures and properties. See also: Article by Gautier et al. Supramolecular sensing: Enzyme activity with a twist   pp275 - 277 David B. Amabilino doi:10.1038/nchem.2208 A supramolecular polymer comprising stacked artificial chromophores to which zinc(II) complexes are appended is able to respond to enzymatic hydrolysis in aqueous solution. The assembly of molecules can twist reversibly and quickly in response to changes in the type of adenosine phosphate present. Protein engineering: The power of four   pp277 - 279 Arnold J. Boersma and Gerard Roelfes doi:10.1038/nchem.2220 Supramolecular assembly has been used to design and create new proteins capable of performing biomimetic functions in complex environments such as membranes and inside living cells. Surface chemistry: A step in the right direction   pp279 - 280 Francisco Zaera doi:10.1038/nchem.2217 Identifying the contribution of different surface sites to the overall kinetics of molecular desorption from solid surfaces is difficult even when using single crystals. A new technique that combines molecular beams with UV-UV double resonance spectroscopy resolves this problem for the case of carbon monoxide on Pt(111). Chemistry JOBS of the week PhD Studentship in Chemistry University of Birmingham PhD in organometallic chemistry National University of Singapore (NUS) Postdoctoral Position in Medicinal Chemistry University of Michigan Research Technician Position in Nucleic Acid Chemistry and Engineering Okinawa Institute of Science and Technology (OIST) PhD and postdoc positions in conformationally controlled chemistry Universität Basel More Science jobs from Chemistry EVENT Biology and Chemistry of Vision 14th June - 19th June 2015 Big Sky, USA More science events from Review Top Supramolecular ferroelectrics   pp281 - 294 Alok S. Tayi, Adrien Kaeser, Michio Matsumoto, Takuzo Aida and Samuel I. Stupp doi:10.1038/nchem.2206 Ferroelectric materials hold much promise for the development of devices such as nonvolatile memories, sensors and nonlinear optic materials. This Review describes the molecular features required to devise organic molecular ferroelectrics, and presents the supramolecular chemistry strategies available for controlling molecular organization and dynamics across different length scales. Articles Top Stepwise growth of surface-grafted DNA nanotubes visualized at the single-molecule level   pp295 - 300 Amani A. Hariri, Graham D. Hamblin, Yasser Gidi, Hanadi F. Sleiman and Gonzalo Cosa doi:10.1038/nchem.2184 DNA nanotubes are attractive building blocks for the assembly of complex arrays. An efficient solid-state synthesis for producing surface-grafted, robust nanotubes has now been devised. Rungs are incorporated in a stepwise manner so that each one is addressable. Using fluorescent tags, the nanotube growth was visualized at the single-molecule level. Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism   pp301 - 307 Bhavesh H. Patel, Claudia Percivalle, Dougal J. Ritson, Colm D. Duffy and John D. Sutherland doi:10.1038/nchem.2202 A minimal cell — one that has all the minimum requirements for life — is still a complex entity comprising informational, compartment-forming and metabolic subsystems. Here it is shown that, contrary to previous assumptions, a common prebiotically plausible chemistry can give rise to building blocks for all the subsystems. Chemical compounds See also: News and Views by Bracher Prediction and accelerated laboratory discovery of previously unknown 18-electron ABX compounds   pp308 - 316 Romain Gautier, Xiuwen Zhang, Linhua Hu, Liping Yu, Yuyuan Lin et al. doi:10.1038/nchem.2207 A method to predict the stability, structure and properties of as-yet-unreported materials has been devised. For 18-valence electron ABX materials, 15 such ‘missing’ compounds identified to be thermodynamically stable were successfully synthesized, and showed crystal structures and properties in good agreement with the predicted ones. See also: News and Views by Walsh Supramolecular nesting of cyclic polymers   pp317 - 322 Dmitry V. Kondratuk, Luís M. A. Perdigão, Ayad M. S. Esmail, James N. O'Shea, Peter H. Beton et al. doi:10.1038/nchem.2182 Biopolymers adopt functional tertiary structures through folding and multiplex formation. Synthetic molecules with protein-like dimensions — monodisperse cyclic porphyrin polymers with diameters of 13–21 nm — have now been shown to exhibit biomimetic self-organization by forming nested structures on a gold surface. These assemblies are formed both under vacuum and during deposition from solution. Chemical compounds Inducing and quantifying forbidden reactivity with single-molecule polymer mechanochemistry   pp323 - 327 Junpeng Wang, Tatiana B. Kouznetsova, Zhenbin Niu, Mitchell T. Ong, Hope M. Klukovich et al. doi:10.1038/nchem.2185 Externally applied mechanical forces can steer molecules along reaction paths that are otherwise inaccessible. Single-molecule force spectroscopy has now been used to quantify the force required to induce symmetry-forbidden reactivity in three different reactions and compare their behaviour to that of the symmetry-allowed analogues. Combined biomass valorization and hydrogen production in a photoelectrochemical cell   pp328 - 333 Hyun Gil Cha and Kyoung-Shin Choi doi:10.1038/nchem.2194 Photoelectrochemical water-splitting produces hydrogen at the cathode and oxygen at the anode. The anode reaction is, however, kinetically unfavourable. Now, reduction of water at the cathode has been combined with oxidation of 5-hydroxymethylfurfural at the anode resulting in a photoelectrochemical cell that produces fuel and a useful platform chemical. Iterative design of a helically folded aromatic oligoamide sequence for the selective encapsulation of fructose   pp334 - 341 Nagula Chandramouli, Yann Ferrand, Guillaume Lautrette, Brice Kauffmann, Cameron David Mackereth et al. doi:10.1038/nchem.2195 Designing synthetic molecular receptors that can differentiate between specific monosaccharide guests is very challenging. Now, a helically folded oligoamide that selectively encapsulates fructose has been designed using an iterative approach that exploits the modular structure of folded synthetic oligomer sequences, in conjunction with molecular modelling and structural characterization. Highly emissive platinum(II) metallacages   pp342 - 348 Xuzhou Yan, Timothy R. Cook, Pi Wang, Feihe Huang and Peter J. Stang doi:10.1038/nchem.2201 Two metallacages containing Pt(II) phosphine centres bridged by organic donors are shown to display dynamic emission behaviour across a range of concentrations. At low concentrations, the individual cages emit. At high concentrations, or on introduction of additional solvents, aggregation occurs that manifests in colour-tunable fluorescence and white-light emission in THF. Chemical compounds Quantum dynamical resonances in low-energy CO(j = 0) + He inelastic collisions   pp349 - 353 Astrid Bergeat, Jolijn Onvlee, Christian Naulin, Ad van der Avoird and Michel Costes doi:10.1038/nchem.2204 Long-lived molecular collision complexes — or ‘resonances’ — are difficult to identify experimentally. Now crossed-beam experiments and quantum calculations are reported for rotationally inelastic CO−He collisions at energies corresponding to temperatures as low as 4 K. Quantum dynamical resonances that are predicted by theory were detected and fully characterized. Two-stage directed self-assembly of a cyclic [3]catenane   pp354 - 358 Christopher S. Wood, Tanya K. Ronson, Ana M. Belenguer, Julian J. Holstein and Jonathan R. Nitschke doi:10.1038/nchem.2205 Interlocked molecules represent some of the most challenging synthetic targets in terms of non-natural products. It has now been demonstrated how a cyclic [3]catenane composed of three mutually interpenetrating rings can be prepared in two stages using a selective imine exchange reaction on a self-assembled triangular precursor. Chemical compounds Erratum Top Erratum: Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig cyclization   p359 Craig P. Johnston, Abhishek Kothari, Tetiana Sergeieva, Sergiy I. Okovytyy, Kelvin E. Jackson et al. doi:10.1038/nchem.2210 In Your Element Top Quantum caesium   p360 Eric Ansoborlo and Richard Wayne Leggett doi:10.1038/nchem.2215 Eric Ansoborlo and Richard Wayne Leggett discuss the chemical and radiological characteristics that make caesium a captivating element but also a troublesome contaminant. Top Advertisement Don't let your data go to waste...   Scientific Data helps researchers make the most of their data, offering publication in a peer reviewed open access journal. We welcome data of all sizes, from all areas of science. What's unique? 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