The EMBO Journal Table of Contents for 18 November 2014; Vol. 33, No. 22

18 November 2014 | Volume 33, Number 22 Submit Table of Contents Editorial Have you seen? Articles Corrigendum Volume 33, Number 22 Editorial Transparent, Reproducible Data New guidelines for the reporting of research and source data enhance the interpretation and reproducibility of published research. Bernd Pulverer Published online 23.10.2014 Have you seen? Shigella hacks host immune responses by reprogramming the host epigenome During infection, Shigella injects effector protein OspF to modulate the epigenetic status of specific host genes. This effect involves dual targeting of both histones and the chromatin reader HP1γ. Hiroshi Ashida and Chihiro Sasakawa Published online 22.09.2014 Splicing together sister chromatids Impaired spliceosome function triggers the loss of sister chromatid cohesion in interphase due a specific sensitivity of sororin to pre‐mRNA splicing. Juan Valcárcel and Marcos Malumbres Published online 29.09.2014 Old dog, new tricks: Arf1 required for mitochondria homeostasis The small G‐protein Arf1 and its GEF regulate mitochondrial quality control and activity, a surprising and conserved function independent of their canonical role in COPI coated vesicle budding and membrane traffic through the secretory pathway. Catherine Rabouille Published online 17.09.2014 Articles Shigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspF The Shigella virulence effector OspF regulates the activity and phosphorylation status of the chromatin reader HP1γ by inactivating the HP1γ kinase MSK1. Habiba Harouz, Christophe Rachez, Benoit M Meijer, Benoit Marteyn, Françoise Donnadieu, Florence Cammas, Christian Muchardt, Philippe Sansonetti, and Laurence Arbibe Published online 12.09.2014 Functional genomics identifies a requirement of pre‐mRNA splicing factors for sister chromatid cohesion Correct splicing of cohesin‐loading factor sororin is required for sister chromatid cohesion during interphase. Mutations in a splicing factor essential for cohesion is implicated in chronic lymphocytic leukemia. Sriramkumar Sundaramoorthy, María Dolores Vázquez‐Novelle, Sergey Lekomtsev, Michael Howell, and Mark Petronczki Published online 25.09.2014 SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre‐mRNAs Loss of splicesome subunits SNW1 and PRPF8 leads to altered intron retention in a specific set of genes and depletes expression of cohesion loading factor sororin, explaining the mitotic defects caused by aberrant pre‐mRNA splicing. Petra van der Lelij, Roman R Stocsits, Rene Ladurner, Georg Petzold, Emanuel Kreidl, Birgit Koch, Julia Schmitz, Beate Neumann, Jan Ellenberg, and Jan‐Michael Peters Published online 25.09.2014 The small GTPase Arf1 modulates mitochondrial morphology and function The GTPase Arf1 and its GEF GBF‐1/Gea1/2 have a role independent of the well known regulation of vesicle trafficking in maintaining mitochondrial dynamics and function via Cdc48 and mitofusin mediated quality control and ER‐mitochondria contact site functionality. Karin B Ackema, Jürgen Hench, Stefan Böckler, Shyi Chyi Wang, Ursula Sauder, Heidi Mergentaler, Benedikt Westermann, Frédéric Bard, Stephan Frank, and Anne Spang Published online 04.09.2014 OPA1‐dependent cristae modulation is essential for cellular adaptation to metabolic demand Metabolic stress causes inner mitochondrial membrane fusion protein OPA1 to interact with solute carriers and to oligomerize to regulate cristae shape, thereby maintaining mitochondrial activity under low energy availability. David A Patten, Jacob Wong, Mireille Khacho, Vincent Soubannier, Ryan J Mailloux, Karine Pilon‐Larose, Jason G MacLaurin, David S Park, Heidi M McBride, Laura Trinkle‐Mulcahy, Mary‐Ellen Harper, Marc Germain, and Ruth S Slack Published online 08.10.2014 Crystal structure of a c‐di‐AMP riboswitch reveals an internally pseudo‐dimeric RNA C‐di‐AMP is a recently discovered second messenger in bacteria that is detected by both RNA and proteins. The crystal structure of ydaO, a c‐di‐AMP binding riboswitch, illustrates the basis for ligand specificity. Christopher P Jones and Adrian R Ferré‐D'Amaré Published online 30.09.2014 Inhibitor‐3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore‐bound protein phosphatase‐1 Intricate interplay of two PP1‐interacting regulators controls Aurora B‐mediated kinetochore phosphorylation to ensure proper chromosome segregation. Annika Eiteneuer, Jonas Seiler, Matthias Weith, Monique Beullens, Bart Lesage, Veronica Krenn, Andrea Musacchio, Mathieu Bollen, and Hemmo Meyer Published online 08.10.2014 Peripheral natural killer cell maturation depends on the transcription factor Aiolos Aiolos, a member of the Ikaros family of transcription factors, regulates the differentiation of mouse natural killer cells. Melissa L Holmes, Nicholas D Huntington, Rebecca PL Thong, Jason Brady, Yoshihiro Hayakawa, Christopher E Andoniou, Peter Fleming, Wei Shi, Gordon K Smyth, Mariapia A Degli‐Esposti, Gabrielle T Belz, Axel Kallies, Sebastian Carotta, Mark J Smyth, and Stephen L Nutt Published online 15.10.2014 Corrigendum Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon Cecilia Rocha, Laura Papon, Wulfran Cacheux, Patricia Marques Sousa, Valeria Lascano, Olivia Tort, Tiziana Giordano, Sophie Vacher, Benedicte Lemmers, Pascale Mariani, Didier Meseure, Jan Paul Medema, Ivan Bièche, Michael Hahne, and Carsten Janke Published online 18.11.2014   Unsubscribe from or edit your subscription for this service. Or by mail: Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2014 by the European Molecular Biology Organisation.