The EDGE

A Seat at the Big Table: Expanding the Role of Dermatology at the World Health Organization and Beyond

Esther E Freeman

J Invest Dermatol 2014 134: 2663-2665; 10.1038/jid.2014.355

Clinical Snippets

J Invest Dermatol 2014 134: 2666; 10.1038/jid.2014.390

BJD Editor's Choice

J Invest Dermatol 2014 134: 2667; 10.1038/jid.2014.391

Editors' Picks

J Invest Dermatol 2014 134: 2668; 10.1038/jid.2014.392

Research Techniques Made Simple

Identifying the Stem Cell

Krisztian Nemeth and Sarolta Karpati

J Invest Dermatol 2014 134: e26; 10.1038/jid.2014.393

JID VisualDx Quiz

JID VisualDx Quiz: November 2014

Jose E Ollague and Robert S Kirsner

J Invest Dermatol 2014 134: e22; 10.1038/jid.2014.394

Cells to Surgery Quiz

Cells to Surgery Quiz: November 2014

Mohammad-Ali Yazdani Abyaneh, Robert D Griffith, Leyre Falto-Aizpurua and Keyvan Nouri

J Invest Dermatol 2014 134: e7; 10.1038/jid.2014.395

In Memoriam

Ruth Kimmelstiel Freinkel (1926–2014)

Amy S Paller and Eugene A Bauer

J Invest Dermatol 2014 134: 2669-2670; 10.1038/jid.2014.386

Meeting Report

Proceedings of the Inaugural Pediatric Dermatology Research Alliance (PeDRA) Conference

Dawn H Siegel, Keith A Choate, Beth A Drolet, Ilona J Frieden, Sheila Rittenberg, Joyce M Teng, Wynnis L Tom, Mary L Williams, Lawrence F Eichenfield and Amy S Paller

J Invest Dermatol 2014 134: 2671-2674; 10.1038/jid.2014.227

Commentaries

Myeloid Cells’ Evasion of Melanoma Immunity

Jun Wang and Lieping Chen

J Invest Dermatol 2014 134: 2675-2677; 10.1038/jid.2014.251

Newly Discovered Olfactory Receptors in Epidermal Keratinocytes Are Associated with Proliferation, Migration, and Re-Epithelialization of Keratinocytes

Mitsuhiro Denda

J Invest Dermatol 2014 134: 2677-2679; 10.1038/jid.2014.229

Perspective

Intravital Multiphoton Imaging of Cutaneous Immune Responses

Kenji Kabashima and Gyohei Egawa

J Invest Dermatol 2014 134: 2680-2684; advance online publication, June 26, 2014; 10.1038/jid.2014.225

Original Articles

APPENDAGES

Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages

Veronika Mlitz, Bettina Strasser, Karin Jaeger, Marcela Hermann, Minoo Ghannadan, Maria Buchberger, Lorenzo Alibardi, Erwin Tschachler and Leopold Eckhart

J Invest Dermatol 2014 134: 2685-2692; advance online publication, April 29, 2014; 10.1038/jid.2014.204

CLINICAL RESEARCH

Abnormally Differentiating Keratinocytes in the Epidermis of Systemic Sclerosis Patients Show Enhanced Secretion of CCN2 and S100A9

Joanna Nikitorowicz-Buniak, Xu Shiwen, Christopher P Denton, David Abraham and Richard Stratton

J Invest Dermatol 2014 134: 2693-2702; advance online publication, June 16, 2014; 10.1038/jid.2014.253

EPIDEMIOLOGY

Socioeconomic Patterning in the Incidence and Survival of Children and Young People Diagnosed with Malignant Melanoma in Northern England

Richard J Q McNally, Nermine O Basta, Steven Errington, Peter W James, Paul D Norman and Alan W Craft

J Invest Dermatol 2014 134: 2703-2708; advance online publication, June 13, 2014; 10.1038/jid.2014.246

IMMUNOLOGY/INFECTION

Natural Killer T Cells Are Essential for the Development of Contact Hypersensitivity in BALB/c Mice

Chihiro Shimizuhira, Atsushi Otsuka, Tetsuya Honda, Akihiko Kitoh, Gyohei Egawa, Saeko Nakajima, Chisa Nakashima, Hiroshi Watarai, Yoshiki Miyachi and Kenji Kabashima

J Invest Dermatol 2014 134: 2709-2718; advance online publication, April 22, 2014; 10.1038/jid.2014.200

Role of ROS and HMGB1 in Contact Allergen–Induced IL-18 Production in Human Keratinocytes

Valentina Galbiati, Angela Papale, Corrado L Galli, Marina Marinovich and Emanuela Corsini

J Invest Dermatol 2014 134: 2719-2727; advance online publication, April 29, 2014; 10.1038/jid.2014.203

Mast Cells Are Key Mediators of Cathelicidin-Initiated Skin Inflammation in Rosacea

Yumiko Muto, Zhenping Wang, Matthieu Vanderberghe, Aimee Two, Richard L Gallo and Anna Di Nardo

J Invest Dermatol 2014 134: 2728-2736; advance online publication, May 20, 2014; 10.1038/jid.2014.222

Trichomide A, a Natural Cyclodepsipeptide, Exerts Immunosuppressive Activity against Activated T Lymphocytes by Upregulating SHP2 Activation to Overcome Contact Dermatitis

Xingqi Wang, Aihua Zhang, Jian Gao, Wei Chen, Shiyu Wang, Xuefeng Wu, Yan Shen, Yuehai Ke, Zichun Hua, Renxiang Tan, Yang Sun and Qiang Xu

J Invest Dermatol 2014 134: 2737-2746; advance online publication, June 16, 2014; 10.1038/jid.2014.252

Propionibacterium acnes Activates the NLRP3 Inflammasome in Human Sebocytes

Zheng Jun Li, Dae Kyoung Choi, Kyung Cheol Sohn, Min Seok Seo, Hae Eul Lee, Young Lee, Young Joon Seo, Young Ho Lee, Ge Shi, Christos C Zouboulis, Chang Deok Kim, Jeung Hoon Lee and Myung Im

J Invest Dermatol 2014 134: 2747-2756; advance online publication, May 12, 2014; 10.1038/jid.2014.221

IL-19 Is a Component of the Pathogenetic IL-23/IL-17 Cascade in Psoriasis

Ellen Witte, Georgios Kokolakis, Katrin Witte, Sandra Philipp, Wolf-Dietrich Doecke, Nina Babel, Bianca M Wittig, Katarzyna Warszawska, Agata Kurek, Magdalena Erdmann-Keding, Stefanie Kunz, Khusru Asadullah, Marshall E Kadin, Hans-Dieter Volk, Wolfram Sterry, Kerstin Wolk and Robert Sabat

J Invest Dermatol 2014 134: 2757-2767; advance online publication, July 21, 2014; 10.1038/jid.2014.308

KERATINOCYTES/EPIDERMIS

Fas/Fas Ligand Mediates Keratinocyte Death in Sunitinib-Induced Hand-Foot Skin Reaction

Chun-Nan Yeh, Wen-Hung Chung, Shih-Chi Su, Yen-Yang Chen, Chi-Tung Cheng, Yen-Ling Lin, Wan-Chun Chang, Rosaline Chung-Yee Hui, Kun-Chun Chiang, Tsung-Wen Chen, Yi-Yin Jan, Chien-Wei Chen, Ting-Jui Chen, Chih-Hsun Yang and Shuen-Iu Hung

J Invest Dermatol 2014 134: 2768-2775; advance online publication, May 6, 2014; 10.1038/jid.2014.218

Interaction of Plectin with Keratins 5 and 14: Dependence on Several Plectin Domains and Keratin Quaternary Structure

Jamal-Eddine Bouameur, Bertrand Favre, Lionel Fontao, Prakash Lingasamy, Nadja Begré and Luca Borradori

J Invest Dermatol 2014 134: 2776-2783; advance online publication, June 18, 2014; 10.1038/jid.2014.255

MELANOCYTES/MELANOMA

DC-HIL-Expressing Myelomonocytic Cells Are Critical Promoters of Melanoma Growth

Jin-Sung Chung, Kyoichi Tamura, Ponciano D Cruz, Jr and Kiyoshi Ariizumi

J Invest Dermatol 2014 134: 2784-2794; advance online publication, June 17, 2014; 10.1038/jid.2014.254

The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells

Stuart J Gallagher, Branka Mijatov, Dilini Gunatilake, Jessamy C Tiffen, Kavitha Gowrishankar, Lei Jin, Gulietta M Pupo, Carleen Cullinane, Rab K Prinjha, Nicholas Smithers, Grant A McArthur, Helen Rizos and Peter Hersey

J Invest Dermatol 2014 134: 2795-2805; advance online publication, June 6, 2014; 10.1038/jid.2014.243

PHOTOBIOLOGY

Sun and Ski Holidays Improve Vitamin D Status, but Are Associated with High Levels of DNA Damage

Bibi Petersen, Hans C Wulf, Margarita Triguero-Mas, Peter A Philipsen, Elisabeth Thieden, Peter Olsen, Jakob Heydenreich, Payam Dadvand, Xavier Basagaña, Tove S Liljendahl, Graham I Harrison, Dan Segerbäck, Alois W Schmalwieser, Antony R Young and Mark J Nieuwenhuijsen

J Invest Dermatol 2014 134: 2806-2813; advance online publication, May 20, 2014; 10.1038/jid.2014.223

TUMOR BIOLOGY

Depletion of M2-Like Tumor-Associated Macrophages Delays Cutaneous T-Cell Lymphoma Development In Vivo

Xuesong Wu, Brian C Schulte, Youwen Zhou, Dipica Haribhai, Alexander C Mackinnon, Jose A Plaza, Calvin B Williams and Sam T Hwang

J Invest Dermatol 2014 134: 2814-2822; advance online publication, April 29, 2014; 10.1038/jid.2014.206

WOUND HEALING

A Synthetic Sandalwood Odorant Induces Wound-Healing Processes in Human Keratinocytes via the Olfactory Receptor OR2AT4

Daniela Busse, Philipp Kudella, Nana-Maria Grüning, Günter Gisselmann, Sonja Ständer, Thomas Luger, Frank Jacobsen, Lars Steinsträßer, Ralf Paus, Paraskevi Gkogkolou, Markus Böhm, Hanns Hatt and Heike Benecke

J Invest Dermatol 2014 134: 2823-2832; advance online publication, July 7, 2014; 10.1038/jid.2014.273

Letters to the Editor

Substance P Is Upregulated in the Serum of Patients with Chronic Spontaneous Urticaria

Martin Metz, Clemens Krull, Tomasz Hawro, Rohit Saluja, Adriane Groffik, Christian Stanger, Petra Staubach and Marcus Maurer

J Invest Dermatol 2014 134: 2833-2836; advance online publication, May 20, 2014; 10.1038/jid.2014.226

Biomechanical Properties of the Skin in Cutis Laxa

Beth A Kozel, Chi-Ting Su, Joshua R Danback, Ryan L Minster, Suneeta Madan-Khetarpal, Juliann S McConnell, Meghan K Mac Neal, Kara L Levine, Robert C Wilson, Frank C Sciurba and Zsolt Urban

J Invest Dermatol 2014 134: 2836-2838; advance online publication, May 20, 2014; 10.1038/jid.2014.224

DC-HIL⁺ CD14⁺ HLA-DR^no/low Cells Are a Potential Blood Marker and Therapeutic Target for Melanoma

Jake Turrentine, Jin-Sung Chung, Kaveh Nezafati, Kyoichi Tamura, Amy Harker-Murray, James Huth, Rohit R Sharma, David B Harker, Kiyoshi Ariizumi and Ponciano D Cruz, Jr

J Invest Dermatol 2014 134: 2839-2842; advance online publication, June 16, 2014; 10.1038/jid.2014.248

Ethnicity and Hidradenitis Suppurativa

Virginia J Reeder, Meredith G Mahan and Iltefat H Hamzavi

J Invest Dermatol 2014 134: 2842-2843; advance online publication, May 12, 2014; 10.1038/jid.2014.220

Abnormal Epidermal Barrier Recovery in Uninvolved Skin Supports the Notion of an Epidermal Pathogenesis of Psoriasis

Li Ye, Chengzhi Lv, George Man, Shunpeng Song, Peter M Elias and Mao-Qiang Man

J Invest Dermatol 2014 134: 2843-2846; advance online publication, April 29, 2014; 10.1038/jid.2014.205

miR-330-5p Targets Tyrosinase and Induces Depigmentation

Florian Rambow, Audrey Bechadergue, Gaelle Saintigny, Frédérique Morizot, Christian Mahé and Lionel Larue

J Invest Dermatol 2014 134: 2846-2849; advance online publication, May 26, 2014; 10.1038/jid.2014.231

Corrigenda

CD8⁺ Granzyme B⁺–Mediated Tissue Injury versus CD4⁺IFNγ⁺–Mediated Parasite Killing in Human Cutaneous Leishmaniasis

Claire da Silva Santos, Viviane Boaventura, Cristina Ribeiro Cardoso, Natalia Tavares, Morgana J Lordelo, Almério Noronha, Jackson Costa, Valéria M Borges, Camila I de Oliveira, Johan Van Weyenbergh, Aldina Barral, Manoel Barral-Netto and Cláudia Ida Brodskyn

J Invest Dermatol 2014 134: 2850; advance online publication, June 19, 2014; 10.1038/jid.2014.230

Flt3L Dependence Helps Define an Uncharacterized Subset of Murine Cutaneous Dendritic Cells

Shamim A Mollah, Joseph S Dobrin, Rachel E Feder, Sze-Wah Tse, Ines G Matos, Cheolho Cheong, Ralph M Steinman and Niroshana Anandasabapathy

J Invest Dermatol 2014 134: 2850-2851; advance online publication, July 10, 2014; 10.1038/jid.2014.234

The Adverse Effect of IFN Gamma on Stratum Corneum Structure and Function in Psoriasis and Atopic Dermatitis

Kenneth R Feingold

J Invest Dermatol 2014 134: 2851; advance online publication, August 14, 2014; 10.1038/jid.2014.298

Replication of Associations between GWAS SNPs and Melanoma Risk in the Population Architecture Using Genomics and Epidemiology (PAGE) Study

Jonathan M Kocarnik, Sungshim Lani Park, Jiali Han, Logan Dumitrescu, Iona Cheng, Lynne R Wilkens, Fredrick R Schumacher, Laurence Kolonel, Chris S Carlson, Dana C Crawford, Robert J Goodloe, Holli Dilks, Paxton Baker, Danielle Richardson, José Luis Ambite, Fengju Song, Abrar A Qureshi, Mingfeng Zhang, David Duggan, Carolyn Hutter, Lucia A Hindorff, William S Bush, Charles Kooperberg, Loic Le Marchand and Ulrike Peters

J Invest Dermatol 2014 134: 2852; advance online publication, August 14, 2014; 10.1038/jid.2014.299

siRNA-Targeting Transforming Growth Factor-β Type I Receptor Reduces Wound Scarring and Extracellular Matrix Deposition of Scar Tissue

Yi-Wen Wang, Nien-Hsien Liou, Juin-Hong Cherng, Shu-Jen Chang, Kuo-Hsing Ma, Earl Fu, Jiang-Chuan Liu and Niann-Tzyy Dai

J Invest Dermatol 2014 134: 2852; advance online publication, August 14, 2014; 10.1038/jid.2014.300