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TABLE OF CONTENTS
|  |  |  | Volume 96, Issue 3 (September 2014) |  | In this issue In This Issue Editorial News & Views Perspectives Discovery & Development Clinical Trial Research Corrigendum
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Listen to the latest podcast from Clinical Pharmacology & Therapeutics and join us as we delve into the advances in the nature, action, efficacy, and evaluation of therapeutics in this cross-disciplinary field of experimental and clinical medicine. Each podcast features highlighted content from Clinical Pharmacology & Therapeutics. |  | | |  |  | In This Issue | Top |  | In This IssueClin Pharmacol Ther 2014 96: 279; 10.1038/clpt.2014.149 Full Text |  | Editorial | Top |  | BiotransformationS Ito Clin Pharmacol Ther 2014 96: 281-283; 10.1038/clpt.2014.133 Abstract | Full Text |  | News & Views | Top |  | HIGHLIGHTS |
Clin Pharmacol Ther 2014 96: 284-285; 10.1038/clpt.2014.148 Full Text |  |  |  | ASCPT NEWS |
Clin Pharmacol Ther 2014 96: 286-289; 10.1038/clpt.2014.135 Full Text |  | Perspectives | Top |  | OPINION | A Question-Based Approach to Adopting Pharmacogenetics to Understand Risk for Clinical Variability in Pharmacokinetics in Early Drug DevelopmentR Evers, R L Blanchard, A W Warner, D Cutler, N G B Agrawal and P M Shaw Clin Pharmacol Ther 2014 96: 291-295; 10.1038/clpt.2014.98 Abstract | Full Text |  |  |  | COMMENTARIES | Genetic Markers of Cisplatin-Induced Hearing Loss in ChildrenB C Carleton, C J Ross, K Pussegoda, A P Bhavsar, H Visscher, J W Lee, B Brooks, S R Rassekh, M-P P Dubé and M R Hayden Clin Pharmacol Ther 2014 96: 296-298; 10.1038/clpt.2014.92 Abstract | Full Text |  |  |  | COMMENTARY | ITC Commentary on the Prediction of Digoxin Clinical Drug–Drug Interactions from In Vitro Transporter AssaysC A Lee, J C Kalvass, A Galetin and M J Zamek-Gliszczynski ; on behalf of the International Transporter Consortium Clin Pharmacol Ther 2014 96: 298-301; 10.1038/clpt.2014.94 Abstract | Full Text |  |  |  | LETTERS TO THE EDITOR | The Failing Right Heart: The Neglected Ventricle?V Ziesenitz, D Köhler and M Gorenflo Clin Pharmacol Ther 2014 96: 302; advance online publication, May 13, 2014; 10.1038/clpt.2014.108 Full Text |  |  |  | Response to “The Failing Right Heart: The Neglected Ventricle?”J Vincent Clin Pharmacol Ther 2014 96: 302-303; advance online publication, June 13, 2014; 10.1038/clpt.2014.132 Full Text |  | Discovery & Development | Top |  | TRANSLATION | Individualizing the Use of Medications in Children: Making Goldilocks HappyJ S Leeder, J T Brown and S E Soden Clin Pharmacol Ther 2014 96: 304-306; advance online publication, June 13, 2014; 10.1038/clpt.2014.130 Abstract | Full Text |  |  |  | DEVELOPMENT | Prerequisites to Implementing a Pharmacogenomics Program in a Large Health-Care SystemK D Levy, B S Decker, J S Carpenter, D A Flockhart, P R Dexter, Z Desta and T C Skaar Clin Pharmacol Ther 2014 96: 307-309; advance online publication, May 7, 2014; 10.1038/clpt.2014.101 Abstract | Full Text |  |  |  | Human iPSC-Derived Miniature Organs: A Tool for Drug StudiesT Takebe and H Taniguchi Clin Pharmacol Ther 2014 96: 310-313; advance online publication, May 21, 2014; 10.1038/clpt.2014.110 Abstract | Full Text |  | Clinical Trial | Top |  | A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure ProphylaxisA G A Jackson, L J Else, P M M Mesquita, D Egan, D J Back, Z Karolia, L Ringner-Nackter, C J Higgs, B C Herold, B G Gazzard and M Boffito Clin Pharmacol Ther 2014 96: 314-323; advance online publication, May 26, 2014; 10.1038/clpt.2014.118 Abstract | Full Text |  | Research | Top |  | REVIEW | Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical ImplicationsC Guillemette, É Lévesque and M Rouleau Clin Pharmacol Ther 2014 96: 324-339; advance online publication, June 12, 2014; 10.1038/clpt.2014.126 Abstract | Full Text |  |  |  | Functional Gene Variants of CYP3A4A N Werk and I Cascorbi Clin Pharmacol Ther 2014 96: 340-348; advance online publication, June 13, 2014; 10.1038/clpt.2014.129 Abstract | Full Text |  |  |  | ARTICLES | Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots OPENM Bosilkovska, C F Samer, J Déglon, M Rebsamen, C Staub, P Dayer, B Walder, J A Desmeules and Y Daali Clin Pharmacol Ther 2014 96: 349-359; advance online publication, April 10, 2014; 10.1038/clpt.2014.83 Abstract | Full Text |  |  |  | Inflammation-Related Genetic Variations and Survival in Patients With Advanced Non–Small Cell Lung Cancer Receiving First-Line ChemotherapyX Pu, M A T Hildebrandt, C Lu, J A Roth, D J Stewart, Y Zhao, R S Heist, Y Ye, D W Chang, L Su, J D Minna, S M Lippman, M R Spitz, D C Christiani and X Wu Clin Pharmacol Ther 2014 96: 360-369; advance online publication, April 22, 2014; 10.1038/clpt.2014.89 Abstract | Full Text |  |  |  | Genetic Variants in Transcription Factors Are Associated With the Pharmacokinetics and Pharmacodynamics of MetforminS Goswami, S W Yee, S Stocker, J D Mosley, M Kubo, R Castro, J A Mefford, C Wen, X Liang, J Witte, C Brett, S Maeda, M D Simpson, M M Hedderson, R L Davis, D M Roden, K M Giacomini and R M Savic Clin Pharmacol Ther 2014 96: 370-379; advance online publication, May 22, 2014; 10.1038/clpt.2014.109 Abstract | Full Text |  |  |  | The Posology of Oseltamivir in Infants With Influenza Infection Using a Population Pharmacokinetic ApproachM A Kamal, E P Acosta, D W Kimberlin, L Gibiansky, P Jester, V Niranjan, B Rath, B Clinch, P J Sánchez, K Ampofo, R Whitley and C R Rayner Clin Pharmacol Ther 2014 96: 380-389; advance online publication, May 27, 2014; 10.1038/clpt.2014.120 Abstract | Full Text |  |  |  | Retreatment With Varenicline for Smoking Cessation in Smokers Who Have Previously Taken Varenicline: A Randomized, Placebo-Controlled Trial OPEND Gonzales, P Hajek, L Pliamm, K Nackaerts, L-J Tseng, T D McRae and J Treadow Clin Pharmacol Ther 2014 96: 390-396; advance online publication, June 9, 2014; 10.1038/clpt.2014.124 Abstract | Full Text |  | Corrigendum | Top |  | Corrigendum: Patients Benefit From Genetics-Guided Coumarin Anticoagulant TherapyClin Pharmacol Ther 2014 96: 397; 10.1038/clpt.2014.142 Full Text |  |  |  | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. 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