The EDGE

A study of the decision outcomes and financial costs of multidisciplinary team meetings (MDMs) in oncology

P B De Ieso, J I Coward, I Letsa, U Schick, M Nandhabalan, S Frentzas and M E Gore

Br J Cancer 2013 109: 2295-2300; advance online publication, October 1, 2013; 10.1038/bjc.2013.586

Quality of life during chemotherapy in lung cancer patients: results across different treatment lines

L M Wintner, J M Giesinger, A Zabernigg, M Sztankay, V Meraner, G Pall, W Hilbe and B Holzner

Br J Cancer 2013 109: 2301-2308; advance online publication, October 3, 2013; 10.1038/bjc.2013.585

Phase II study of dovitinib in patients with metastatic and/or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib

Y-K Kang, C Yoo, B-Y Ryoo, J J Lee, E Tan, I Park, J H Park, Y J Choi, J Jo, J-S Ryu and M-H Ryu

Br J Cancer 2013 109: 2309-2315; advance online publication, October 1, 2013; 10.1038/bjc.2013.594

Validation of the prognostic relevance of plasma C-reactive protein levels in soft-tissue sarcoma patients

J Szkandera, A Gerger, B Liegl-Atzwanger, G Absenger, M Stotz, H Samonigg, W Maurer-Ertl, T Stojakovic, F Ploner, A Leithner and M Pichler

Br J Cancer 2013 109: 2316-2322; advance online publication, October 1, 2013; 10.1038/bjc.2013.595

Identification of serum miRNAs as novel non-invasive biomarkers for detection of high risk for early gastric cancer

A Shiotani, T Murao, Y Kimura, H Matsumoto, T Kamada, H Kusunoki, K Inoue, N Uedo, H Iishi and K Haruma

Br J Cancer 2013 109: 2323-2330; advance online publication, October 8, 2013; 10.1038/bjc.2013.596

Aromatase inhibitor-induced modulation of breast density: clinical and genetic effects

N L Henry, H-P Chan, J Dantzer, C P Goswami, L Li, T C Skaar, J M Rae, Z Desta, N Khouri, R Pinsky, S Oesterreich, C Zhou, L Hadjiiski, S Philips, J Robarge, A T Nguyen, A M Storniolo, D A Flockhart, D F Hayes, M A Helvie and V Stearns

Br J Cancer 2013 109: 2331-2339; advance online publication, October 1, 2013; 10.1038/bjc.2013.587

High-risk features in radiation-associated breast angiosarcomas

S P D'Angelo, C R Antonescu, D Kuk, L Qin, N Moraco, R C Carvajal, P Chi, M A Dickson, M Gounder, M L Keohan, S Singer, G K Schwartz and W D Tap

Br J Cancer 2013 109: 2340-2346; advance online publication, October 8, 2013; 10.1038/bjc.2013.590

Somatic copy number changes in DPYD are associated with lower risk of recurrence in triple-negative breast cancers

E Gross, C Meul, S Raab, C Propping, S Avril, M Aubele, A Gkazepis, T Schuster, N Grebenchtchikov, M Schmitt, M Kiechle, J Meijer, R Vijzelaar, A Meindl and A B P van Kuilenburg

Br J Cancer 2013 109: 2347-2355; advance online publication, October 8, 2013; 10.1038/bjc.2013.621

Translational Therapeutics

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

M Kaliszczak, H Patel, S H B Kroll, L Carroll, G Smith, S Delaney, D A Heathcote, A Bondke, M J Fuchter, R C Coombes, A G M Barrett, S Ali and E O Aboagye

Br J Cancer 2013 109: 2356-2367; advance online publication, September 26, 2013; 10.1038/bjc.2013.584

Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer

C Zeng, S Vangveravong, J E McDunn, W G Hawkins and R H Mach

Br J Cancer 2013 109: 2368-2377; advance online publication, October 8, 2013; 10.1038/bjc.2013.593

Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents

G He, J Kuang, J Koomen, R Kobayashi, A R Khokhar and Z H Siddik

Br J Cancer 2013 109: 2378-2388; advance online publication, October 8, 2013; 10.1038/bjc.2013.613

Molecular Diagnostics

Acquired resistance to temsirolimus in human renal cell carcinoma cells is mediated by the constitutive activation of signal transduction pathways through mTORC2

K Harada, H Miyake, M Kumano and M Fujisawa

Br J Cancer 2013 109: 2389-2395; advance online publication, October 3, 2013; 10.1038/bjc.2013.602

The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome

S M Robinson, D A Mann, D M Manas, F Oakley, J Mann and S A White

Br J Cancer 2013 109: 2396-2403; advance online publication, October 10, 2013; 10.1038/bjc.2013.604

A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material

N G Bediaga, M P A Davies, A Acha-Sagredo, R Hyde, O Y Raji, R Page, M Walshaw, J Gosney, A Alfirevic, J K Field and T Liloglou

Br J Cancer 2013 109: 2404-2411; advance online publication, October 10, 2013; 10.1038/bjc.2013.623

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2

D Bedognetti, T L Spivey, Y Zhao, L Uccellini, S Tomei, M E Dudley, M L Ascierto, V De Giorgi, Q Liu, L G Delogu, M Sommariva, M R Sertoli, R Simon, E Wang, S A Rosenberg and F M Marincola

Br J Cancer 2013 109: 2412-2423; advance online publication, October 15, 2013; 10.1038/bjc.2013.557

Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis

G Celesti, G Di Caro, P Bianchi, F Grizzi, F Marchesi, G Basso, D Rahal, G Delconte, M Catalano, P Cappello, M Roncalli, A Zerbi, M Montorsi, F Novelli, A Mantovani, P Allavena, A Malesci and L Laghi

Br J Cancer 2013 109: 2424-2433; advance online publication, October 1, 2013; 10.1038/bjc.2013.565

p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

M J Groves, C E Johnson, J James, A R Prescott, J Cunningham, S Haydock, C Pepper, C Fegan, L Pirrie, N J Westwood, P J Coates, I G Ganley and S Tauro

Br J Cancer 2013 109: 2434-2444; advance online publication, October 3, 2013; 10.1038/bjc.2013.601

Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis

J A C M Goos, V M H Coupe, B Diosdado, P M Delis-Van Diemen, C Karga, J A M Beliën, B Carvalho, M P van den Tol, H M W Verheul, A A Geldof, G A Meijer, O S Hoekstra and R J A Fijneman on behalf of the DeCoDe PET group

Br J Cancer 2013 109: 2445-2452; advance online publication, October 8, 2013; 10.1038/bjc.2013.608

Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial

J M S Bartlett, C L Brookes, T Piper, C J H van de Velde, D Stocken, N Lyttle, A Hasenburg, M A Quintayo, D G Kieback, H Putter, C Markopoulos, E M-K Kranenbarg, E A Mallon, L Y Dirix, C Seynaeve and D W Rea

Br J Cancer 2013 109: 2453-2461; advance online publication, October 3, 2013; 10.1038/bjc.2013.609

Epidemiology

Prognostic value of ABO blood group in southern Chinese patients with established nasopharyngeal carcinoma

P-Y OuYang, Z Su, Y-P Mao, Q Liu and F-Y Xie

Br J Cancer 2013 109: 2462-2466; advance online publication, September 10, 2013; 10.1038/bjc.2013.559

Immediate and delayed effects of mammographic screening on breast cancer mortality and incidence in birth cohorts

T M Ripping, A L M Verbeek, D van der Waal, J D M Otten, G J den Heeten, J Fracheboud, H J de Koning and M J M Broeders

Br J Cancer 2013 109: 2467-2471; advance online publication, October 10, 2013; 10.1038/bjc.2013.627

The association between different night shiftwork factors and breast cancer: a case–control study

L Fritschi, T C Erren, D C Glass, J Girschik, A K Thomson, C Saunders, T Boyle, S El-Zaemey, P Rogers, S Peters, T Slevin, A D'Orsogna, F de Vocht, R Vermeulen and J S Heyworth

Br J Cancer 2013 109: 2472-2480; advance online publication, September 10, 2013; 10.1038/bjc.2013.544

Clinical-guide risk prediction of hepatocellular carcinoma development in chronic hepatitis C patients after interferon-based therapy

K-C Chang, Y-Y Wu, C-H Hung, S-N Lu, C-M Lee, K-W Chiu, M-C Tsai, P-L Tseng, C-M Huang, C-L Cho, H-H Chen and T-H Hu

Br J Cancer 2013 109: 2481-2488; advance online publication, October 1, 2013; 10.1038/bjc.2013.564

'Socioeconomic position and survival after cervical cancer: influence of cancer stage, comorbidity and smoking among Danish women diagnosed between 2005 and 2010

E H Ibfelt, S K Kjær, C Høgdall, M Steding-Jessen, T K Kjær, M Osler, C Johansen, K Frederiksen and S O Dalton

Br J Cancer 2013 109: 2489-2495; advance online publication, September 12, 2013; 10.1038/bjc.2013.558

Cancer risk in patients with Hashimoto’s thyroiditis: a nationwide cohort study

Y-K Chen, C-L Lin, F T-F Cheng, F-C Sung and C-H Kao

Br J Cancer 2013 109: 2496-2501; advance online publication, October 1, 2013; 10.1038/bjc.2013.597

Letters to the Editor

Comment on ‘Prevalence of the metabolic syndrome and cardiovascular disease risk in chemotherapy-treated testicular germ cell tumour survivors’

M Singhera and R Huddart

Br J Cancer 2013 109: 2502-2503; advance online publication, September 17, 2013; 10.1038/bjc.2013.566

Reply: ‘Comment on Prevalence of the metabolic syndrome and cardiovascular disease risk in chemotherapy-treated testicular germ cell tumour survivors’

P M Willemse, J Burggraaf, N A T Hamdy and S Osanto

Br J Cancer 2013 109: 2503-2504; advance online publication, September 17, 2013; 10.1038/bjc.2013.567

Comment on ‘Phase III randomised controlled trial of neoadjuvant chemotherapy plus radical surgery vs radical surgery alone for stages IB2, IIA2, and IIB cervical cancer: a Japan Clinical Oncology Group trial (JCOG 0102)’

H Nagano

Br J Cancer 2013 109: 2505; advance online publication, September 24, 2013; 10.1038/bjc.2013.581

Reply: ‘Comment on Phase III randomised controlled trial of neoadjuvant chemotherapy plus radical surgery vs radical surgery alone for stages IB2, IIA2, and IIB cervical cancer: a Japan Clinical Oncology Group trial (JCOG 0102)’

N Katsumata

Br J Cancer 2013 109: 2506; advance online publication, September 24, 2013; 10.1038/bjc.2013.582