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| TABLE OF CONTENTS | |||||||||||||||||||||||||||||||||||||
| July 2013 Volume 14 Number 7 | |||||||||||||||||||||||||||||||||||||
| In this issue
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| In this issue p453 | doi:10.1038/nrn3545 Full Text | |||||||||||||||||||||||||||||||||||||
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| REVIEWS | Top | ||||||||||||||||||||||||||||||||||||
| Acid-sensing ion channels in pain and disease John A. Wemmie, Rebecca J. Taugher & Collin J. Kreple p461 | doi:10.1038/nrn3529 Acid-sensing ion channels (ASICs) have been implicated in pain, and neurological and psychiatric disease. Wemmie et al. provide an update on the roles of ASICs in health and disease, and consider the implications for therapy and future lines of research. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
| The histaminergic network in the brain: basic organization and role in disease Pertti Panula & Saara Nuutinen p472 | doi:10.1038/nrn3526 The histaminergic neuromodulatory system has important roles in in the regulation of cognition, sleep and wakefulness, and feeding and energy balance. In this Review, Panula and Nuutinen briefly explore histamine's physiological functions before focusing on its roles in various brain disorders. Abstract | Full Text | PDF | Supplementary information | |||||||||||||||||||||||||||||||||||||
| Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective Dan W. Grupe & Jack B. Nitschke p488 | doi:10.1038/nrn3524 In order to anticipate and prepare effectively for future experiences, the brain must cope with the inherent uncertainty of future events. In this Review, Grupe and Nitschke show how alterations in the processes by which the brain deals with future uncertainty may contribute to the development of pathological anxiety. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
| Cognitive and emotional control of pain and its disruption in chronic pain M. Catherine Bushnell, Marta Čeko & Lucie A. Low p502 | doi:10.1038/nrn3516 Chronic pain is associated with changes in brain structure and function resulting in altered cognition and affect. Bushnell et al. examine the mechanisms underlying the psychological modulation of pain and the potential of mind-body therapies to alleviate chronic pain. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
| PERSPECTIVES | Top | ||||||||||||||||||||||||||||||||||||
| SCIENCE AND SOCIETY The influence of neuroscience on US Supreme Court decisions about adolescents' criminal culpability Laurence Steinberg p513 | doi:10.1038/nrn3509 The changes that occur in the brain during adolescence have been a topic of increasing interest in the past decade. Steinberg discusses how progress in adolescent brain research has influenced US Supreme Court decisions in three landmark cases about the criminal culpability of adolescents. Abstract | Full Text | PDF | |||||||||||||||||||||||||||||||||||||
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| *2012 Journal Citation Report (Thomson Reuters, 2013) |
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