Molecular Systems Biology - New articles published 19 February 2013

Latest Articles 19th Feb 2013   Featured Article Report   Web feeds About Open access   Advertisement The winner of the 2013 FEBS | EMBO Women in Science Award is Geneviève Almouzni from the Institut Curie in Paris, France. She received the award in recognition of her outstanding research on chromatin dynamics and her commitment to mentoring women pursuing a career in science. Molecular Systems Biology congratulates Geneviève Almouzni for her achievements.   Featured Article Programming biological models in Python using PySB PySB is a framework for creating biological models as Python programs using a high-level, action-oriented vocabulary that promotes transparency, extensibility and reusability. PySB interoperates with many existing modeling tools and supports distributed model development. Carlos F Lopez, Jeremy L Muhlich, John A Bachman & Peter K Sorger Molecular Systems Biology 9:646; doi:10.1038/msb.2013.1; published 19 February 2013 Full Text | PDF | Supp. Inf. | Review Process Report Epigenetic epistatic interactions constrain the evolution of gene expression Harmful epistatic (genetic) interactions not only occur between mutations, but also when genes change in expression. Gene expression dynamics in yeast suggests that this ‘epigenetic’ epistasis constrains evolution, with the tight regulation of network hubs promoting a robust, ‘canalized’ phenotype. Solip Park & Ben Lehner Molecular Systems Biology 9:645; doi:10.1038/msb.2013.2; published 19 February 2013 Full Text | PDF | Supp. Inf. | Review Process

Advertisement

Molecular Systems Biology - New Reviews Series Reading and writing omes Church doi:10.1038/msb.2012.75 Genome-scale engineering for systems and synthetic biology Esvelt & Wang doi:10.1038/msb.2012.66 High-throughput sequencing for biology and medicine Soon, Hariharan & Snyder doi:10.1038/msb.2012.61 Read free content at www.nature.com/msb/focus

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. For other enquiries, please contact our customer feedback department. Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2013 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.