Wednesday, February 6, 2013

British Journal of Cancer - Table of Contents alert Volume 108 Issue 2


TABLE OF CONTENTS

Volume 108, Issue 2 (245-476)
Published online 5 February 2013

In this issue
Minireview
Clinical Studies
Translational Therapeutics
Molecular Diagnostics
Genetics & Genomics

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British Journal of Cancer presents:
Web Focus on Lifestyle

Lifestyle is now known to contribute significantly to global cancer burdens. We highlight here some recent studies and meta-analyses that identify various factors associated with risk of developing cancer.

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Minireview

Top

Functional genomic screening to enhance oncolytic virotherapy

D J Mahoney and D F Stojdl

Br J Cancer 2013 108: 245-249; advance online publication, November 20, 2012; 10.1038/bjc.2012.467

Abstract | Full Text

Targeted anti-vascular therapies for ovarian cancer: current evidence

M Hall, C Gourley, I McNeish, J Ledermann, M Gore, G Jayson, T Perren, G Rustin and S Kaye

Br J Cancer 2013 108: 250-258; 10.1038/bjc.2012.541

Abstract | Full Text

Clinical Studies

Top

Epidural methadone results in dose-dependent analgesia in cancer pain, further enhanced by epidural dexamethasone

G R Lauretti, C C Rizzo, A L Mattos and S W Rodrigues

Br J Cancer 2013 108: 259-264; advance online publication, January 15, 2013; 10.1038/bjc.2012.593

Abstract | Full Text

A randomised multicentre phase II study with cisplatin/docetaxel vs oxaliplatin/docetaxel as first-line therapy in patients with advanced or metastatic non-small cell lung cancer

A Atmaca, S-E Al-Batran, D Werner, C Pauligk, T Güner, A Koepke, H Bernhard, T Wenzel, A-G Banat, P Brueck, K Caca, N Prasnikar, F Kullmann, H Günther Derigs, M Koenigsmann, G Dingeldein, T Neuhaus and E Jäger

Br J Cancer 2013 108: 265-270; advance online publication, January 17, 2013; 10.1038/bjc.2012.555

Abstract | Full Text

Prognostic value of Ki-67 for prostate cancer death in a conservatively managed cohort

G Fisher, Z H Yang, S Kudahetti, H Møller, P Scardino, J Cuzick and D M Berney on behalf of the Transatlantic Prostate Group

Br J Cancer 2013 108: 271-277; advance online publication, January 17, 2013; 10.1038/bjc.2012.598

Abstract | Full Text

Telomerase is an independent prognostic marker of overall survival in patients with colorectal cancer

R Bertorelle, M Briarava, E Rampazzo, L Biasini, M Agostini, I Maretto, S Lonardi, M L Friso, C Mescoli, V Zagonel, D Nitti, A De Rossi and S Pucciarelli

Br J Cancer 2013 108: 278-284; advance online publication, January 15, 2013; 10.1038/bjc.2012.602

Abstract | Full Text

Clinical benefit from neoadjuvant chemotherapy in oestrogen receptor-positive invasive ductal and lobular carcinomas

Y Delpech, C Coutant, L Hsu, E Barranger, T Iwamoto, C H Barcenas, G N Hortobagyi, R Rouzier, F J Esteva and L Pusztai

Br J Cancer 2013 108: 285-291; advance online publication, January 8, 2013; 10.1038/bjc.2012.557

Abstract | Full Text

Differences in cancer awareness and beliefs between Australia, Canada, Denmark, Norway, Sweden and the UK (the International Cancer Benchmarking Partnership): do they contribute to differences in cancer survival?

L J L Forbes, A E Simon, F Warburton, D Boniface, K E Brain, A Dessaix, C Donnelly, K Haynes, L Hvidberg, M Lagerlund, G Lockwood, C Tishelman, P Vedsted, M N Vigmostad, A J Ramirez and J Wardle the International Cancer Benchmarking Partnership Module 2 Working Group

Br J Cancer 2013 108: 292-300; advance online publication, January 31, 2013; 10.1038/bjc.2012.542

Abstract | Full Text

Validation of the EORTC QLQ-GINET21 questionnaire for assessing quality of life of patients with gastrointestinal neuroendocrine tumours

G Yadegarfar, L Friend, L Jones, L M Plum, J Ardill, B Taal, G Larsson, K Jeziorski, D Kwekkeboom and J K Ramage on behalf of the EORTC Quality of Life Group

Br J Cancer 2013 108: 301-310; advance online publication, January 15, 2013; 10.1038/bjc.2012.560

Abstract | Full Text

Sorafenib tolerability in elderly patients with advanced renal cell carcinoma: results from a large pooled analysis

G Procopio, J Bellmunt, J Dutcher, S Bracarda, J Knox, A Brueckner, I Molnar, B Escudier and T E Hutson

Br J Cancer 2013 108: 311-318; advance online publication, January 15, 2013; 10.1038/bjc.2012.543

Abstract | Full Text

Translational Therapeutics

Top

Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts

X Wang, L Zhang, A O'Neill, B Bahamon, D C Alsop, J W Mier, S N Goldberg, S Signoretti, M B Atkins, C G Wood and R S Bhatt

Br J Cancer 2013 108: 319-326; advance online publication, January 15, 2013; 10.1038/bjc.2012.591

Abstract | Full Text

Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo

W C Duivenvoorden, L K Beatty, S Lhotak, B Hill, I Mak, G Paulin, D Gallino, S Popovic, R C Austin and J H Pinthus

Br J Cancer 2013 108: 327-333; advance online publication, January 15, 2013; 10.1038/bjc.2012.574

Abstract | Full Text

Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenografts

C Eicher, A Dewerth, J Thomale, V Ellerkamp, S Hildenbrand, S W Warmann, J Fuchs and S Armeanu-Ebinger

Br J Cancer 2013 108: 334-341; advance online publication, December 20, 2012; 10.1038/bjc.2012.539

Abstract | Full Text

A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

M Kaliszczak, S Trousil, O Åberg, M Perumal, Q-D Nguyen and E O Aboagye

Br J Cancer 2013 108: 342-350; advance online publication, January 15, 2013; 10.1038/bjc.2012.576

Abstract | Full Text

Molecular Diagnostics

Top

Tissue biomarkers of breast cancer and their association with conventional pathologic features

L Chung, S Shibli, K Moore, E E Elder, F M Boyle, D J Marsh and R C Baxter

Br J Cancer 2013 108: 351-360; advance online publication, January 8, 2013; 10.1038/bjc.2012.552

Abstract | Full Text

Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer

T Kawaguchi, S Komatsu, D Ichikawa, R Morimura, M Tsujiura, H Konishi, H Takeshita, H Nagata, T Arita, S Hirajima, A Shiozaki, H Ikoma, K Okamoto, T Ochiai, H Taniguchi and E Otsuji

Br J Cancer 2013 108: 361-369; advance online publication, January 17, 2013; 10.1038/bjc.2012.546

Abstract | Full Text

The epigenetic landscape of oral squamous cell carcinoma

P V Jithesh, J M Risk, A G Schache, J Dhanda, B Lane, T Liloglou and R J Shaw

Br J Cancer 2013 108: 370-379; advance online publication, January 3, 2013; 10.1038/bjc.2012.568

Abstract | Full Text

Fasting blood glucose is a novel prognostic indicator for extranodal natural killer/T-cell lymphoma, nasal type

Q Cai, X Luo, Y Liang, H Rao, X Fang, W Jiang, T Lin, T Lin and H Huang

Br J Cancer 2013 108: 380-386; advance online publication, January 8, 2013; 10.1038/bjc.2012.566

Abstract | Full Text

Erythrocyte sedimentation rate and anaemia are independent predictors of survival in patients with clear cell renal cell carcinoma

Y Choi, B Park, K Kim, B C Jeong, S I Seo, S S Jeon, H Y Choi, J E Lee and H M Lee

Br J Cancer 2013 108: 387-394; advance online publication, January 8, 2013; 10.1038/bjc.2012.565

Abstract | Full Text

REG Iα is a biomarker for predicting response to chemotherapy with S-1 plus cisplatin in patients with unresectable stage IV gastric cancer

A Sekikawa, H Fukui, X Zhang, T Maruo, T Tsumura, Y Okabe, T Wakasa, Y Osaki, T Chiba, T Tomita, T Oshima, J Watari and H Miwa

Br J Cancer 2013 108: 395-401; advance online publication, January 15, 2013; 10.1038/bjc.2012.572

Abstract | Full Text

Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix

A Mayer, M Höckel, N Schlischewsky, H Schmidberger, L-C Horn and P Vaupel

Br J Cancer 2013 108: 402-408; advance online publication, January 15, 2013; 10.1038/bjc.2012.570

Abstract | Full Text

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells

K M Dixon, G Y L Lui, Z Kovacevic, D Zhang, M Yao, Z Chen, Q Dong, S J Assinder and D R Richardson

Br J Cancer 2013 108: 409-419; advance online publication, January 3, 2013; 10.1038/bjc.2012.582

Abstract | Full Text

Prognostic significance of aberrantly silenced ANPEP expression in prostate cancer

K D Sørensen, M O Abildgaard, C Haldrup, B P Ulhøi, H Kristensen, S Strand, C Parker, S Høyer, M Borre and T F Ørntoft

Br J Cancer 2013 108: 420-428; advance online publication, January 15, 2013; 10.1038/bjc.2012.549

Abstract | Full Text

Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations

D J Pinato, R Ramachandran, S T K Toussi, M Vergine, N Ngo, R Sharma, T Lloyd, K Meeran, F Palazzo, N Martin, B Khoo, R Dina and T M Tan

Br J Cancer 2013 108: 429-437; advance online publication, December 20, 2012; 10.1038/bjc.2012.538

Abstract | Full Text

Genetics & Genomics

Top

An intronic polymorphic deletion in the PTEN gene: implications for molecular diagnostic testing

S Sandell, R J L Schuit and D J Bunyan

Br J Cancer 2013 108: 438-441; advance online publication, January 8, 2013; 10.1038/bjc.2012.562

Abstract | Full Text

Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells

S Carbajo-Pescador, C Steinmetz, A Kashyap, S Lorenz, J L Mauriz, M Heise, P R Galle, J González-Gallego and S Strand

Br J Cancer 2013 108: 442-449; advance online publication, December 20, 2012; 10.1038/bjc.2012.563

Abstract | Full Text

Lack of correlation between predicted and actual off-target effects of short-interfering RNAs targeting the human papillomavirus type 16 E7 oncogene

J E Hanning, H K Saini, M J Murray, S van Dongen, M P A Davis, E M Barker, D M Ward, C G Scarpini, A J Enright, M R Pett and N Coleman

Br J Cancer 2013 108: 450-460; advance online publication, January 8, 2013; 10.1038/bjc.2012.564

Abstract | Full Text

An inherited NBN mutation is associated with poor prognosis prostate cancer

C Cybulski, D Wokołorczyk, W Kluźniak, A Jakubowska, B Górski, J Gronwald, T Huzarski, A Kashyap, T Byrski, T Dębniak, A Gołąb, B Gliniewicz, A Sikorski, J Świtała, T Borkowski, A Borkowski, A Antczak, Ł Wojnar, J Przybyła, M Sosnowski, B Małkiewicz, R Zdrojowy, P Sikorska-Radek, J Matych, J Wilkosz, W Różański, J Kiś, K Bar, P Bryniarski, A Paradysz, K Jersak, J Niemirowicz, P Słupski, P Jarzemski, M Skrzypczyk, J Dobruch, P Domagała, S A Narod and J Lubiński the Polish Hereditary Prostate Cancer Consortium

Br J Cancer 2013 108: 461-468; advance online publication, November 13, 2012; 10.1038/bjc.2012.486

Abstract | Full Text

EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104

S Boeck, A Jung, R P Laubender, J Neumann, R Egg, C Goritschan, U Vehling-Kaiser, C Winkelmann, L Fischer von Weikersthal, M R Clemens, T C Gauler, A Märten, S Klein, G Kojouharoff, M Barner, M Geissler, T F Greten, U Mansmann, T Kirchner and V Heinemann

Br J Cancer 2013 108: 469-476; advance online publication, November 20, 2012; 10.1038/bjc.2012.495

Abstract | Full Text

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