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| | | 20 November 2012 | | | Featured image: | |  | | | Orsenigo et al. show that phosphorylated VE-cadherin regulates vascular permeability in veins but not in arteries. | | | | | | |
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In partnership with: KACST | | | | | | | | Latest Articles | View all Articles | | | | | Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource OPEN | | | Caleb S. Heffner, C. Herbert Pratt, Randal P. Babiuk, Yashoda Sharma, Stephen F. Rockwood, Leah R. Donahue, Janan T. Eppig and Stephen A. Murray | | | The cre-loxP system is widely used for the generation of conditional gene knockouts. Here Heffner et al. systematically characterize cre recombinase activity in tissues of embryonic and adult cre-driver mouse strains and provide an online resource for scientists. | | | 20 Nov | Nat Commun 3:1218 doi:10.1038/ncomms2186 (2012) | | | Biological sciences Genetics | | Abstract | Full Text | PDF (4,668 kB) |
Supplementary Information |
| On-chip transformation optics for multimode waveguide bends | | | Lucas H. Gabrielli, David Liu, Steven G. Johnson and Michal Lipson | | | Integrated photonic devices rely on single-mode waveguides, as inter-mode coupling prevents multimode waveguides from being efficiently bent for on-chip schemes. Using transformation optics, Gabrielli et al. overcome this limitation and show a multimode waveguide bend with minimal inter-mode coupling. | | | 20 Nov | Nat Commun 3:1217 doi:10.1038/ncomms2232 (2012) | | | Physical sciences Nanotechnology | | | Optical physics | | | Abstract | Full Text | PDF (1,164 kB) |
| Flexible and low-voltage integrated circuits constructed from high-performance nanocrystal transistors | | | David K. Kim, Yuming Lai, Benjamin T. Diroll, Christopher B. Murray and Cherie R. Kagan | | | Field-effect transistors based on semiconductor nanocrystals are promising candidates for low-cost, flexible electronics. This work demonstrates fabrication on flexible substrates and low-voltage operations of integrated circuits based on nanocrystal transistors, including amplifiers and ring oscillators. | | | 20 Nov | Nat Commun 3:1216 doi:10.1038/ncomms2218 (2012) | | | Physical sciences Applied physics | | | Materials science | | | Nanotechnology | | Abstract | Full Text | PDF (641 kB) |
Supplementary Information |
| Synthesis of chiral TiO2 nanofibre with electron transition-based optical activity OPEN | | | Shaohua Liu, Lu Han, Yingying Duan, Shunsuke Asahina, Osamu Terasaki, Yuanyuan Cao, Ben Liu, Liguo Ma, Jialiang Zhang and Shunai Che | | | Optical activity resulting from electronic transitions in chiral inorganic materials is rare. Liu et al. report the synthesis of amino acid-derived amphiphile templated chiral TiO2 fibres, which exhibit an optical response to polarized light resulting from valence to conduction band electronic transitions. | | | 20 Nov | Nat Commun 3:1215 doi:10.1038/ncomms2215 (2012) | | | Chemical sciences Materials science | | Abstract | Full Text | PDF (1,069 kB) |
Supplementary Information |
| Cellulose degradation and assimilation by the unicellular phototrophic eukaryote Chlamydomonas reinhardtii | | | Olga Blifernez-Klassen, Viktor Klassen, Anja Doebbe, Klaudia Kersting, Philipp Grimm, Lutz Wobbe and Olaf Kruse | | | Although cellulose is abundant in the biosphere, its potential as a source of biofuel depends on finding efficient ways to degrade it. Blifernez-Klassen et al. show that phototrophic microalga Chlamydomonas reinhardtii can metabolize cellulose, indicating its potential as a catalyst for biofuel production. | | | 20 Nov | Nat Commun 3:1214 doi:10.1038/ncomms2210 (2012) | | | Biological sciences Biochemistry | | | Biotechnology Plant sciences | | Abstract | Full Text | PDF (1,456 kB) |
Supplementary Information |
| Broadband electromagnetic cloaking with smart metamaterials | | | Dongheok Shin, Yaroslav Urzhumov, Youngjean Jung, Gumin Kang, Seunghwa Baek, Minjung Choi, Haesung Park, Kyoungsik Kim and David R. Smith | | | Metamaterial cloaks can manipulate light to effectively hide objects from view, but they mostly rely on rigid structures that are tailored specifically for the chosen object. Shin et al. demonstrate an elastic, smart metamaterial cloak that can adapt to a range of deformations and object sizes. | | | 20 Nov | Nat Commun 3:1213 doi:10.1038/ncomms2219 (2012) | | | Physical sciences Materials science | | | Optical physics | | | Abstract | Full Text | PDF (2,201 kB) |
| Scalable organocatalytic asymmetric Strecker reactions catalysed by a chiral cyanide generator | | | Hailong Yan, Joong Suk Oh, Ji-Woong Lee and Choong Eui Song | | | The Strecker synthesis is an established method for the production of α-amino acids. Here, a scalable catalytic asymmetric Strecker reaction is reported that allows one-pot synthesis of enantiomerically pure α-amino acids. | | | 20 Nov | Nat Commun 3:1212 doi:10.1038/ncomms2216 (2012) | | | Chemical sciences Catalysis | | | Organic chemistry | | Abstract | Full Text | PDF (368 kB) |
Supplementary Information |
| Experimental observation of quantum chaos in a beam of light | | | Gabriela B. Lemos, Rafael M. Gomes, Stephen P. Walborn, Paulo H. Souto Ribeiro and Fabricio Toscano | | | Chaotic dynamics can arise in quantum systems as well as classical ones, leading to its own interesting phenomena. Using an all-optical approach, Lemos et al. study the quantum-kicked harmonic oscillator and its nonlinear dynamics, controlling and mapping the transition into quantum chaotic behaviour. | | | 20 Nov | Nat Commun 3:1211 doi:10.1038/ncomms2214 (2012) | | | Physical sciences Optical physics | | | | Abstract | Full Text | PDF (1,650 kB) |
Supplementary Information |
| Hopping transport and the Hall effect near the insulator—metal transition in electrochemically gated poly(3-hexylthiophene) transistors | | | Shun Wang, Mingjing Ha, Michael Manno, C Daniel Frisbie and C Leighton | | | Understanding charge transport and the fundamental limits on conductivity in polymer semiconductors is important for improving device performance. Wang et al. report a transport regime close to band-like conduction and the observation of the Hall effect in an electrochemically-doped polymer semiconductor. | | | 20 Nov | Nat Commun 3:1210 doi:10.1038/ncomms2213 (2012) | | | Physical sciences Condensed matter | | | Materials science | | | | Abstract | Full Text | PDF (794 kB) |
Supplementary Information |
| Driving diffusionless transformations in colloidal crystals using DNA handshaking | | | Marie T. Casey, Raynaldo T. Scarlett, W. Benjamin Rogers, Ian Jenkins, Talid Sinno and John C. Crocker | | | Crystalline material may be stabilized by complementary DNA interactions but its subsequent capacity for structural transformation is poorly understood. Here, by tuning the DNA handshaking between two sets of nanoparticles, a Martensitic transformation within the binary colloidal crystals is observed. | | | 20 Nov | Nat Commun 3:1209 doi:10.1038/ncomms2206 (2012) | | | Chemical sciences Materials science | | | Nanotechnology | | Abstract | Full Text | PDF (1,435 kB) |
Supplementary Information |
| Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo OPEN | | | Fabrizio Orsenigo, Costanza Giampietro, Aldo Ferrari, Monica Corada, Ariane Galaup, Sara Sigismund, Giuseppe Ristagno, Luigi Maddaluno, Gou Young Koh, Davide Franco, Vartan Kurtcuoglu, Dimos Poulikakos, Peter Baluk, Donald McDonald, Maria Grazia Lampugnani and Elisabetta Dejana | | | Vascular endothelial-cadherin is a junctional protein implicated in the control of vascular permeability. Orsenigo et al. find that vascular endothelial-cadherin is phosphorylated in veins but not in arteries of mice, and that this sensitizes vessels to rapid changes in permeability in response to inflammatory mediators. | | | 20 Nov | Nat Commun 3:1208 doi:10.1038/ncomms2199 (2012) | | | Biological sciences Cell biology | | | | Abstract | Full Text | PDF (11,862 kB) |
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