Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 92 Issue 4

TABLE OF CONTENTS Volume 92, Issue 4 (October 2012) In this issue In This Issue Editorial News & Views Perspectives Discovery & Development Regulation & Use Clinical Trial State of the Art Research Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement A new online open access journal from Clinical Pharmacology & Therapeutics. Sign me up for this alert Publishing advances in quantitative methods as applied in pharmacology, physiology, and therapeutics in humans with a common focus on the application of these two areas on drug development.   In This Issue Top In This Issue Clin Pharmacol Ther 2012 92: 399; 10.1038/clpt.2012.161 Full Text Editorial Top Achieving the Promise of Personalized Medicine K S Reynolds Clin Pharmacol Ther 2012 92: 401-405; 10.1038/clpt.2012.147 Abstract | Full Text News & Views Top Highlights Clin Pharmacol Ther 2012 92: 406-407; 10.1038/clpt.2012.160 Full Text ASCPT News Clin Pharmacol Ther 2012 92: 408-410; 10.1038/clpt.2012.148 Full Text Perspectives Top COMMENTARIES Without an Adequate Ethical Infrastructure, the Road to Personalized Medicine Will Be Rocky at Best A L Caplan Clin Pharmacol Ther 2012 92: 411-412; 10.1038/clpt.2012.142 Abstract | Full Text Ready When You Are: Easing Into Preemptive Pharmacogenetics Y J He and H L McLeod Clin Pharmacol Ther 2012 92: 412-414; 10.1038/clpt.2012.144 Abstract | Full Text Pharmacogenomics Knowledge for Personalized Medicine M Whirl-Carrillo, E M McDonagh, J M Hebert, L Gong, K Sangkuhl, C F Thorn, R B Altman and T E Klein Clin Pharmacol Ther 2012 92: 414-417; 10.1038/clpt.2012.96 Abstract | Full Text Individualized Dosing With Anesthetic Agents H J M Lemmens and D R Stanski Clin Pharmacol Ther 2012 92: 417-419; 10.1038/clpt.2012.131 Abstract | Full Text In Search of Physiologically Based Distribution Volume Estimates for Macromolecules P D Garzone and A J Atkinson, Jr. Clin Pharmacol Ther 2012 92: 419-421; 10.1038/clpt.2012.156 Abstract | Full Text Discovery & Development Top DISCOVERY Population Imaging as Valuable Tool for Personalized Medicine H Völzke, C O Schmidt, K Hegenscheid, J-P Kühn, F Bamberg, W Lieb, H K Kroemer, N Hosten and R Puls Clin Pharmacol Ther 2012 92: 422-424; advance online publication, August 22, 2012; 10.1038/clpt.2012.100 Abstract | Full Text Clinical Translation of Cell-Based Pharmacogenomic Discovery N J Cox, E R Gamazon, H E Wheeler and M E Dolan Clin Pharmacol Ther 2012 92: 425-427; advance online publication, August 22, 2012; 10.1038/clpt.2012.115 Abstract | Full Text The Relevance of “Missing Heritability ” in Pharmacogenomics W Sadee Clin Pharmacol Ther 2012 92: 428-430; advance online publication, August 22, 2012; 10.1038/clpt.2012.116 Full Text TRANSLATION Individualization of Tamoxifen Treatment for Breast Carcinoma L Binkhorst, T van Gelder and R H J Mathijssen Clin Pharmacol Ther 2012 92: 431-433; advance online publication, August 22, 2012; 10.1038/clpt.2012.94 Abstract | Full Text Interpreting Pharmacogenetic Data in the Developing Neonate: The Challenge of Hitting a Moving Target J S Leeder and G L Kearns Clin Pharmacol Ther 2012 92: 434-436; advance online publication, September 5, 2012; 10.1038/clpt.2012.130 Abstract | Full Text Implementing Personalized Medicine: Development of a Cost-Effective Customized Pharmacogenetics Genotyping Array J A Johnson, B M Burkley, T Y Langaee, M J Clare-Salzler, T E Klein and R B Altman Clin Pharmacol Ther 2012 92: 437-439; advance online publication, August 22, 2012; 10.1038/clpt.2012.125 Abstract | Full Text DEVELOPMENT Progress Toward Personalized Treatment of Rheumatoid Arthritis M P Keith, J D Edison and W R Gilliland Clin Pharmacol Ther 2012 92: 440-442; advance online publication, August 22, 2012; 10.1038/clpt.2012.124 Abstract | Full Text Regulation & Use Top PRACTICE Strategies for Personalized Medicine–Based Research and Implementation in the Clinical Workflow W Lieb, H Völzke, J M Pulley, D M Roden and H K Kroemer Clin Pharmacol Ther 2012 92: 443-445; advance online publication, August 22, 2012; 10.1038/clpt.2012.119 Abstract | Full Text The 1200 Patients Project: Creating a New Medical Model System for Clinical Implementation of Pharmacogenomics P H O'Donnell, A Bush, J Spitz, K Danahey, D Saner, S Das, N J Cox and M J Ratain Clin Pharmacol Ther 2012 92: 446-449; advance online publication, August 29, 2012; 10.1038/clpt.2012.117 Abstract | Full Text Clinical Trial Top The Effect of Safinamide, a Novel Drug for Parkinson's Disease, on Pressor Response to Oral Tyramine: A Randomized, Double-Blind, Clinical Trial A Marquet, K Kupas, A Johne, B Astruc, A Patat, S Krösser and A Kovar Clin Pharmacol Ther 2012 92: 450-457; advance online publication, September 5, 2012; 10.1038/clpt.2012.128 Abstract | Full Text State of the Art Top Individualization of Drug Therapy: History, Present State, and Opportunities for the Future L J Lesko and S Schmidt Clin Pharmacol Ther 2012 92: 458-466; advance online publication, September 5, 2012; 10.1038/clpt.2012.113 Abstract | Full Text Pharmacogenomics and Individualized Medicine: Translating Science Into Practice K R Crews, J K Hicks, C-H Pui, M V Relling and W E Evans Clin Pharmacol Ther 2012 92: 467-475; advance online publication, September 5, 2012; 10.1038/clpt.2012.120 Abstract | Full Text Personalizing Antiplatelet Therapy With Clopidogrel D Trenk, O Zolk, M F Fromm, F-J Neumann and W Hochholzer Clin Pharmacol Ther 2012 92: 476-485; advance online publication, September 5, 2012; 10.1038/clpt.2012.133 Abstract | Full Text Advancing the Science of Medicines Regulation: The Role of the 21st-Century Medicines Regulator M M Lumpkin, H-G Eichler, A Breckenridge, M A Hamburg, T Lönngren and K Woods Clin Pharmacol Ther 2012 92: 486-493; advance online publication, September 5, 2012; 10.1038/clpt.2012.146 Abstract | Full Text Research Top ARTICLES Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro–In Vivo Extrapolation Model M Siccardi, L Almond, A Schipani, C Csajka, C Marzolini, C Wyen, N H Brockmeyer, M Boffito, A Owen and D Back Clin Pharmacol Ther 2012 92: 494-502; advance online publication, July 18, 2012; 10.1038/clpt.2012.61 Abstract | Full Text Polymorphisms in Endothelial Nitric Oxide Synthase (eNOS) and Vascular Endothelial Growth Factor (VEGF) Predict Sunitinib-Induced Hypertension K Eechoute, A A M van der Veldt, S Oosting, M H W Kappers, J A M Wessels, H Gelderblom, H-J Guchelaar, A K L Reyners, C M L van Herpen, J B Haanen, R H J Mathijssen and E Boven Clin Pharmacol Ther 2012 92: 503-510; advance online publication, September 5, 2012; 10.1038/clpt.2012.136 Abstract | Full Text Influence of Environmental and Genetic Factors on CYP1A2 Activity in Individuals of South Asian and European Ancestry V Perera, A S Gross and A J McLachlan Clin Pharmacol Ther 2012 92: 511-519; advance online publication, September 5, 2012; 10.1038/clpt.2012.139 Abstract | Full Text Semi-mechanistic Population Pharmacokinetic Model of Multivalent Trastuzumab Emtansine in Patients with Metastatic Breast Cancer V L Chudasama, F Schaedeli Stark, J M Harrold, J Tibbitts, S R Girish, M Gupta, N Frey and D E Mager Clin Pharmacol Ther 2012 92: 520-527; advance online publication, September 12, 2012; 10.1038/clpt.2012.153 Abstract | Full Text Advertisement Ensure your access If you are unable to access the articles in thisalert, your library may not subscribe to this journal. 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