Thursday, August 30, 2012

Drugmakers seek replacements for expiring cardio blockbusters

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August 30, 2012
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  Today's Top Story 
 
  • Drugmakers seek replacements for expiring cardio blockbusters
    Expiring patents for best-selling cardiovascular drugs, including Bristol-Myers Squibb and Sanofi's anti-clotting drug Plavix and Pfizer's cholesterol-lowering treatment Lipitor, have left drugmakers scrambling for next-generation replacements. The patent losses could drag down sales of cardiovascular drugs to $60 billion by 2017 from $83 billion last year, according to analysts' forecasts. Reuters (8/29) LinkedInFacebookTwitterEmail this Story
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  Health Care & Policy 
  • FDA panel supports use of Abbott's Humira for ulcerative colitis
    An FDA advisory panel recommended approval of Abbott Laboratories' Humira as a treatment for ulcerative colitis, saying that the drug's benefits surpass its risks. Humira already is cleared for six other indications, including Crohn's disease and rheumatoid arthritis. The FDA is expected to complete its review this year. Reuters (8/28) LinkedInFacebookTwitterEmail this Story
  • Kyowa halts late-stage trial of ArQule's lung cancer drug tivantinib
    ArQule said partner Kyowa Hakko Kirin ceased enrollment in a Phase III trial of experimental lung cancer drug tivantinib because of suspected cases of interstitial lung disease. The study is evaluating the efficacy of tivantinib combined with Roche Holding's Tarceva, or erlotinib, against a combination of Tarceva and placebo in treating patients with nonsquamous nonsmall-cell lung cancer. The suspension likely won't affect other trials of tivantinib, analysts said. Reuters (8/29) LinkedInFacebookTwitterEmail this Story
  • Researchers grow sperm cells from skin cells
    U.S. researchers have induced early-stage sperm cells from adult skin cells. The development indicates that it may be possible to grow human sperm from induced pluripotent stem cells, a researcher said. The method has the potential to lead to advances that address infertility and help cancer survivors become fathers. The Telegraph (London) (8/29) LinkedInFacebookTwitterEmail this Story
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  Food & Agriculture 
  • Researchers report findings of cotton genome-sequencing project
    An international team of researchers announced that they have sequenced and have begun comparing the genomes of Gossypium raimondii, a wild South American cotton species, with previously sequenced plants and they found that the cotton, like cacao plants, has a family of CDN1 genes that play a role in the production of a compound used to drive away some herbivores and potential pathogens. The project will "provide a major source of candidate genes important for the genetic improvement of cotton quality and productivity," said researchers from the Chinese Academy of Agricultural Sciences' Cotton Research Institute. GenomeWeb Daily News (free registration) (8/27) LinkedInFacebookTwitterEmail this Story
  Industrial & Environmental 
  • Calls for RFS waiver could drive away investors, BIO exec says
    Calls from a group of governors for a temporary suspension of the Renewable Fuel Standard is sending a negative signal to investors in advanced biofuels, according to biofuel groups during a conference call Tuesday. "I think just the fact that people are filing waivers kind of creates turbulence in the system," said BIO executive vice president Brent Erickson. The Hill/E2 Wire blog (8/28) LinkedInFacebookTwitterEmail this Story
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