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|  | | 08 May 2012 |  | | Featured image: |  |  |  | | Lu et al. use scanning tunnelling microscopy to monitor the coalescence of Moiré blisters into geometric nanobubbles in graphene. |
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A growing number of conditions are now linked to dysbiosis of the gut microbiota (such as IBD, cancer and obesity). This Nature Reviews Gastroenterology & Hepatology collection considers the gut microbiota's role in health and disease as well as innovative health-care approaches that target this microbial 'organ'.
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|  | | | | | | Latest Articles | View all Articles | | | |  | Tuning the magneto-structural properties of non-porous coordination polymers by HCl chemisorption |  | | Eugenio Coronado, Mónica Giménez-Marqués, Guillermo Mínguez Espallargas and Lee Brammer |  | | Tuning the properties of responsive materials by applying an external stimulus could lead to their application as chemical switches or molecular sensors. Coronado et al. develop a non-porous one-dimensional coordination polymer, the magnetic properties of which undergo drastic changes on chemisorption of gaseous HCl. |  | | 08 May | Nat Commun 3:828 doi:10.1038/ncomms1827 (2012) |  | | Chemical sciences Inorganic chemistry |  | | Materials science |  | Abstract | Full Text | PDF (952 kB) | Supplementary Information |

 
 | Potential regime shift in decreased sea ice production after the Mertz Glacier calving OPEN |  | | T. Tamura, G.D. Williams, A.D. Fraser and K.I. Ohshima |  | | The calving of the Mertz Glacier occurred in 2010 in East Antarctica, brought on by the re-positioning of a large iceberg. Using satellite data, this study shows a reduction in sea ice production following the calving, interpreted as a potential regime shift towards reduced sea ice production for the coming decades. |  | | 08 May | Nat Commun 3:826 doi:10.1038/ncomms1820 (2012) |  | | Earth sciences Climate science |  | | Oceanography |  | Abstract | Full Text | PDF (4,709 kB) | Supplementary Information |

 | Bridging quantum and classical plasmonics with a quantum-corrected model OPEN |  | | Ruben Esteban, Andrei G. Borisov, Peter Nordlander and Javier Aizpurua |  | | As lengthscales in plasmonic structures enter the sub-nanometre regime, quantum effects become increasingly important. Here, a quantum-corrected model is presented that addresses quantum effects in realistic-sized plasmonic structures, a situation not feasible for full-quantum-mechanical simulations. |  | | 08 May | Nat Commun 3:825 doi:10.1038/ncomms1806 (2012) |  | | Physical sciences Nanotechnology |  | | Optical physics |  | Abstract | Full Text | PDF (949 kB) | Supplementary Information |

 | Molecular preservation of the pigment melanin in fossil melanosomes |  | | Johan Lindgren, Per Uvdal, Peter Sjövall, Dan E. Nilsson, Anders Engdahl, Bo Pagh Schultz and Volker Thiel |  | | Putative fossil melanosomes have been reported but, because their shape and size correspond well with those of bacteria, further evidence is required to confirm their identity. This study reports evidence of melanin in association with melanosome-like microbodies in an argentinoid fish eye from the early Eocene. |  | | 08 May | Nat Commun 3:824 doi:10.1038/ncomms1819 (2012) |  | | Biological sciences Cell biology |  | | Evolution Palaeontology |  | Abstract | Full Text | PDF (1,092 kB) | Supplementary Information |

 
 | Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster |  | | Michael T. Bocker, Francesca Tuorto, Günter Raddatz, Tanja Musch, Feng-Chun Yang, Mingjiang Xu, Frank Lyko and Achim Breiling |  | | Hox gene expression is induced upon cellular differentiation and is inhibited in pluripotent cells. Bocker and colleagues show that the maintenance of induced transcription depends on Tet2 mediated hydroxylation of 5-methylcytosine at the Hoxa gene locus, indicating that this epigenetic switch is required for an active chromatin state and gene expression. |  | | 08 May | Nat Commun 3:818 doi:10.1038/ncomms1826 (2012) |  | | Biological sciences Developmental biology |  | | Molecular biology |  | |  | Abstract | Full Text | PDF (1,103 kB) | Supplementary Information |

 | JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency OPEN |  | | Anouk L. van Oosten, Yael Costa, Austin Smith and José C.R. Silva |  | | Culture conditions are critical for the successful induction of pluripotent stem cells and define whether cells are primed or naïve. Here, activation of JAK/STAT3 signalling is shown to be sufficient and dominant over antagonistic cues to enable the induction of a naïve pluripotent state in stem cells. |  | | 08 May | Nat Commun 3:817 doi:10.1038/ncomms1822 (2012) |  | | Biological sciences Cell biology |  | | Developmental biology |  | Abstract | Full Text | PDF (2,694 kB) | Supplementary Information |

 | The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H+ channel Hv1 OPEN |  | | Yuichiro Fujiwara, Tatsuki Kurokawa, Kohei Takeshita, Megumi Kobayashi, Yoshifumi Okochi, Atsushi Nakagawa and Yasushi Okamura |  | | In the dimeric voltage-gated H+ channel, Hv1/VSOP, the gating of each subunit is coupled, but the molecular basis of dimer formation and intersubunit coupling is unclear. This study shows that channel assembly and cooperative gating are mediated by the cytoplasmic domain. |  | | 08 May | Nat Commun 3:816 doi:10.1038/ncomms1823 (2012) |  | | Biological sciences Biophysics |  | |  | Abstract | Full Text | PDF (1,681 kB) | Supplementary Information |

 | Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression |  | | Li Zheng, Huifang Dai, Mian Zhou, Xiaojin Li, Changwei Liu, Zhigang Guo, Xiwei Wu, Jun Wu, Charles Wang, John Zhong, Qin Huang, Julio Garcia-Aguilar, Gerd P. Pfeifer and Binghui Shen |  | | Tumour cells are subject to replication stress but how cells overcome damage without inducing senescence and apoptotic pathways is unclear. Here, the authors study polyploidy in cancer cells and show that this blocks apoptotic and senescent pathways, resulting in the induction of proteins involved in DNA repair. |  | | 08 May | Nat Commun 3:815 doi:10.1038/ncomms1825 (2012) |  | | Biological sciences Biochemistry |  | | Cancer Molecular biology |  | Abstract | Full Text | PDF (1,328 kB) | Supplementary Information |

 | The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2 OPEN |  | | Guillermo López-Doménech, Román Serrat, Serena Mirra, Salvatore D'Aniello, Ildiko Somorjai, Alba Abad, Nathalia Vitureira, Elena García-Arumí, María Teresa Alonso, Macarena Rodriguez-Prados, Ferran Burgaya, Antoni L. Andreu, Javier García-Sancho, Ramón Trullas, Jordi Garcia-Fernàndez and Eduardo Soriano |  | | Mitochondrial dynamics and trafficking are important for providing energy for neuron function. In this study, the Armadillo repeat containing proteins clustered on the X chromosome are shown to be highly expressed in the nervous system and have a role in mitochondrial dynamics. |  | | 08 May | Nat Commun 3:814 doi:10.1038/ncomms1829 (2012) |  | | Biological sciences Cell biology |  | | Evolution Genetics |  | Abstract | Full Text | PDF (1,728 kB) | Supplementary Information |

 | Attosecond tracing of correlated electron-emission in non-sequential double ionization OPEN |  | | Boris Bergues, Matthias Kübel, Nora G. Johnson, Bettina Fischer, Nicolas Camus, Kelsie J. Betsch, Oliver Herrwerth, Arne Senftleben, A. Max Sayler, Tim Rathje, Thomas Pfeifer, Itzik Ben-Itzhak, Robert R. Jones, Gerhard G. Paulus, Ferenc Krausz, Robert Moshammer, Joachim Ullrich and Matthias F. Kling |  | | Studying the dynamics of electrons is important for understanding fundamental processes in materials. Here the ionization of a pair of electrons in argon atoms is explored on attosecond timescales, offering insight into their correlated emission and the double ionization mechanism. |  | | 08 May | Nat Commun 3:813 doi:10.1038/ncomms1807 (2012) |  | | Physical sciences Atomic and molecular physics |  | |  | | Abstract | Full Text | PDF (674 kB) |
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