TABLE OF CONTENTS
| | | | Volume 91, Issue 6 (June 2012) | | In this issue In This Issue Editorial News & Views Perspectives Clinical Trials State of the Art Review Research Discovery & Development Corrigendum
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| | | In This Issue | Top | | In This IssueClin Pharmacol Ther 2012 91: 947; 10.1038/clpt.2012.60 Full Text | | Editorial | Top | | Translational Bioinformatics: Data-driven Drug Discovery and DevelopmentA J Butte and S Ito Clin Pharmacol Ther 2012 91: 949-952; 10.1038/clpt.2012.55 Abstract | Full Text | | News & Views | Top | | HIGHLIGHTS
| HighlightsClin Pharmacol Ther 2012 91: 954-955; 10.1038/clpt.2012.59 Full Text | | | | ASCPT NEWS
| ASCPT NewsClin Pharmacol Ther 2012 91: 956-959; 10.1038/clpt.2012.56 Full Text | | | | MACROSCOPY
| Drug Research and Translational BioinformaticsL J Lesko Clin Pharmacol Ther 2012 91: 960-962; 10.1038/clpt.2012.45 Full Text | | Perspectives | Top | | OPINION
| Needs for an Expanded Ontology-Based Classification of Adverse Drug Reactions and Related MechanismsP E Zhichkin, B D Athey, M I Avigan and D R Abernethy Clin Pharmacol Ther 2012 91: 963-965; 10.1038/clpt.2012.41 Abstract | Full Text | | | | Healthy Volunteer Registries and Ethical Research PrinciplesE A Kupetsky-Rincon and W K Kraft Clin Pharmacol Ther 2012 91: 965-968; 10.1038/clpt.2012.32 Abstract | Full Text | | | | COMMENTARY
| The Perils of Gene PatentsS L Salzberg Clin Pharmacol Ther 2012 91: 969-971; 10.1038/clpt.2012.6 Abstract | Full Text | | | | LETTERS TO THE EDITOR
| The Role of Cannabinoids in Chronic Pain Patients Remains HazyB C Chen and R S Hoffman Clin Pharmacol Ther 2012 91: 972; advance online publication, April 25, 2012; 10.1038/clpt.2012.27 Full Text | | | | Response to “The Role of Cannabinoids in Chronic Pain Patients Remains Hazy”D I Abrams, P Couey, S B Shade, M E Kelly and N L Benowitz Clin Pharmacol Ther 2012 91: 972-973; advance online publication, April 25, 2012; 10.1038/clpt.2012.36 Full Text | | | | Tissue-Engineered Airway in the Clinical Setting: A Call for Information DisclosureA Wurtz and E Kipnis Clin Pharmacol Ther 2012 91: 973-974; advance online publication, April 25, 2012; 10.1038/clpt.2012.7 Full Text | | | | Response to “Tissue-Engineered Airway in the Clinical Setting: A Call for Information Disclosure”P Macchiarini and P Jungebluth Clin Pharmacol Ther 2012 91: 974; advance online publication, May 2, 2012; 10.1038/clpt.2012.52 Full Text | | Clinical Trials | Top | | Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical TrialP Hoever, G Dorffner, H Beneš, T Penzel, H Danker-Hopfe, M J Barbanoj, G Pillar, B Saletu, O Polo, D Kunz, J Zeitlhofer, S Berg, M Partinen, C L Bassetti, B Högl, I O Ebrahim, E Holsboer-Trachsler, H Bengtsson, Y Peker, U-M Hemmeter, E Chiossi, G Hajak and J Dingemanse Clin Pharmacol Ther 2012 91: 975-985; advance online publication, May 2, 2012; 10.1038/clpt.2011.370 Abstract | Full Text | | | | Comparative Impact on Prostanoid Biosynthesis of Celecoxib and the Novel Nonsteroidal Anti-Inflammatory Drug CG100649C Skarke, N Alamuddin, J A Lawson, L Cen, K J Propert and G A FitzGerald Clin Pharmacol Ther 2012 91: 986-993; advance online publication, January 25, 2012; 10.1038/clpt.2012.3 Abstract | Full Text | | State of the Art | Top | | Translational Bioinformatics: Linking the Molecular World to the Clinical WorldR B Altman Clin Pharmacol Ther 2012 91: 994-1000; advance online publication, May 2, 2012; 10.1038/clpt.2012.49 Abstract | Full Text | | | | Whole-Genome Sequencing in Personalized TherapeuticsP Cordero and E A Ashley Clin Pharmacol Ther 2012 91: 1001-1009; advance online publication, May 2, 2012; 10.1038/clpt.2012.51 Abstract | Full Text | | Review | Top | | Novel Data-Mining Methodologies for Adverse Drug Event Discovery and AnalysisR Harpaz, W DuMouchel, N H Shah, D Madigan, P Ryan and C Friedman Clin Pharmacol Ther 2012 91: 1010-1021; advance online publication, May 2, 2012; 10.1038/clpt.2012.50 Abstract | Full Text | | Research | Top | | REPORT
| Associations Between ABCC2 Polymorphisms and Cisplatin Disposition and EfficacyJ A Sprowl, V Gregorc, C Lazzari, R H Mathijssen, W J Loos and A Sparreboom Clin Pharmacol Ther 2012 91: 1022-1026; advance online publication, April 25, 2012; 10.1038/clpt.2011.330 Abstract | Full Text | | | | ARTICLES
| Prediction of Weight Loss and Regain Following Dietary, Lifestyle, and Pharmacologic InterventionA Napolitano, S R Miller, P R Murgatroyd, B Delafont, A Brooke, M Elkhawad, C Y Tan, S Virtue, A Vidal-Puig and D J Nunez Clin Pharmacol Ther 2012 91: 1027-1034; advance online publication, February 15, 2012; 10.1038/clpt.2011.333 Abstract | Full Text | | | | PhRMA Survey of Pharmacogenomic and Pharmacodynamic Evaluations: What Next?N Grecco, N Cohen, A W Warner, C Lopez-Correa, S L Truter, A Snapir, S P Piccoli, D Wang, A Westelinck, L Hinman and M A Franc ; on behalf of the Industry Pharmacogenomics Working Group Clin Pharmacol Ther 2012 91: 1035-1043; advance online publication, April 25, 2012; 10.1038/clpt.2011.334 Abstract | Full Text | | | | PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In VivoKathrin Klein, Maria Thomas, Stefan Winter, Andreas K. Nussler, Mikko Niemi, Matthias Schwab and Ulrich M. Zanger Clin Pharmacol Ther 2012 91: 1044-1052; advance online publication, April 18, 2012; 10.1038/clpt.2011.336 Abstract | Full Text | | | | Transporter-Mediated Drug–Drug Interactions Involving OATP Substrates: Predictions Based on In Vitro Inhibition StudiesK Yoshida, K Maeda and Y Sugiyama Clin Pharmacol Ther 2012 91: 1053-1064; advance online publication, April 25, 2012; 10.1038/clpt.2011.351 Abstract | Full Text | | | | Comparative Effects of Angiotensin Receptor Blockade and ACE Inhibition on the Fibrinolytic and Inflammatory Responses to Cardiopulmonary BypassF T Billings, IV, J M Balaguer, C Yu, P Wright, M R Petracek, J G Byrne, N J Brown and M Pretorius Clin Pharmacol Ther 2012 91: 1065-1073; advance online publication, May 2, 2012; 10.1038/clpt.2011.356 Abstract | Full Text | | | | Dermal Application of Nitric Oxide In Vivo: Kinetics, Biological Responses, and Therapeutic Potential in HumansC Opländer, A Römer, A Paunel-Görgülü, T Fritsch, E E van Faassen, M Mürtz, A Bozkurt, G Grieb, Paul Fuchs, Norbert Pallua and C V Suschek Clin Pharmacol Ther 2012 91: 1074-1082; advance online publication, May 2, 2012; 10.1038/clpt.2011.366 Abstract | Full Text | | Discovery & Development | Top | | TRANSLATION
| Electronic Medical Records as a Tool in Clinical Pharmacology: Opportunities and ChallengesD M Roden, H Xu, J C Denny and R A Wilke Clin Pharmacol Ther 2012 91: 1083-1086; advance online publication, April 25, 2012; 10.1038/clpt.2012.42 Abstract | Full Text | | Corrigendum | Top | | CORRIGENDUM: Activity Levels of Tamoxifen Metabolites at the Estrogen Receptor and the Impact of Genetic Polymorphisms of Phase I and II Enzymes on Their Concentration Levels in PlasmaClin Pharmacol Ther 2012 91: 1087; 10.1038/clpt.2012.33 Full Text | | | | | | Advertisement | | Ensure your access If you are unable to access the articles in thisalert, your library may not subscribe to this journal. Our online recommendation form is a simple way to make your librarian aware that this journal is valuable to your research. Recommend now at http://www.nature.com/librec/svc/request/makeProdRequest?id=clpt |
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