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|  | | 21 February 2012 | | | Featured image: | |  | | | Taubert et al. find octave-wide band gaps in plasmonic Bragg structures fabricated from gold nanowires. | | | | | | |
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Onyx Pharmaceuticals, Inc. | | | | | | | | | Latest Articles | View all Articles | | | | | Evidence for the stress-linked immunocompetence handicap hypothesis in humans | | | Markus J. Rantala, Fhionna R. Moore, Ilona Skrinda, Tatjana Krama, Inese Kivleniece, Sanita Kecko and Indrikis Krams | | | Testosterone-dependent traits are thought to give an honest signal of male immune function, however, the exact effects remain unclear. This study shows a positive relationship between testosterone, facial attractiveness and the immune response to a hepatitis B vaccine, which is moderated by naturally co-occurring cortisol. | | | 21 Feb | Nat Commun 3:694 doi:10.1038/ncomms1696 (2012) | | | Biological sciences Ecology | | | Evolution Immunology | | | Abstract | Full Text | PDF (346 kB) |
| Humans and chimpanzees attend differently to goal-directed actions | | | Masako Myowa-Yamakoshi, Céline Scola and Satoshi Hirata | | | Humans understand actions by making inferences about the person's intentions. Comparing humans with chimpanzees, this study shows that humans refer to the actors' faces more than chimpanzees do when observing goal-directed actions, indicating that humans view actions by integrating information from the actor. | | | 21 Feb | Nat Commun 3:693 doi:10.1038/ncomms1695 (2012) | | | Biological sciences Evolution Neuroscience | | | Zoology | | Abstract | Full Text | PDF (386 kB) |
Supplementary Information |
| Broadband omnidirectional antireflection coating based on subwavelength surface Mie resonators OPEN | | | P. Spinelli, M.A. Verschuuren and A. Polman | | | Minimising reflection from the interface between materials is an important goal for optical devices such as solar cells or photodetectors. Spinelli et al. show almost total loss of reflection over a broad spectral range from a silicon surface using periodic arrays of sub-wavelength silicon nanocylinders. | | | 21 Feb | Nat Commun 3:692 doi:10.1038/ncomms1691 (2012) | | | Physical sciences Nanotechnology | | | Optical physics | | Abstract | Full Text | PDF (518 kB) |
Supplementary Information |
| Octave-wide photonic band gap in three-dimensional plasmonic Bragg structures and limitations of radiative coupling OPEN | | | Richard Taubert, Daniel Dregely, Tineke Stroucken, Andre Christ and Harald Giessen | | | Radiative interactions between oscillators in optical systems produce new optical properties. Here, radiative coupling in a Bragg-fashioned, stacked arrangement of plasmonic structures yields a tunable photonic band gap of up to one octave at optical frequencies. | | | 21 Feb | Nat Commun 3:691 doi:10.1038/ncomms1694 (2012) | | | Physical sciences Nanotechnology | | | Optical physics | | | | | Abstract | Full Text | PDF (897 kB) |
| Fully inorganic oxide-in-oxide ultraviolet nanocrystal light emitting devices | | | Sergio Brovelli, Norberto Chiodini, Roberto Lorenzi, Alessandro Lauria, Marco Romagnoli and Alberto Paleari | | | Light-emitting diodes in the form of nanocrystals offer promise for environmental and biomedical diagnostics. Brovelli et al. present a method for realizing mechanically robust and chemically stable nanocrystals emitting light in the ultraviolet range. | | | 21 Feb | Nat Commun 3:690 doi:10.1038/ncomms1683 (2012) | | | Physical sciences Materials science Nanotechnology | | | Optical physics | | Abstract | Full Text | PDF (1,256 kB) |
Supplementary Information |
| Wide bandgap tunability in complex transition metal oxides by site-specific substitution | | | Woo Seok Choi, Matthew F. Chisholm, David J. Singh, Taekjib Choi, Gerald E. Jellison , Jr. and Ho Nyung Lee | | | Tuning the bandgap of complex transition metal oxides in a manner that preserves their intrinsic properties has so far remained elusive. Choi et al. demonstrate that the bandgap of bismuth titanate can be varied by substitutional alloying with lanthanum cobaltate, without altering its ferroelectric properties. | | | 21 Feb | Nat Commun 3:689 doi:10.1038/ncomms1690 (2012) | | | Physical sciences Applied physics | | | Condensed matter Materials science | | Abstract | Full Text | PDF (712 kB) |
Supplementary Information |
| miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia | | | Zejuan Li, Hao Huang, Ping Chen, Miao He, Yuanyuan Li, Stephen Arnovitz, Xi Jiang, Chunjiang He, Elizabeth Hyjek, Jun Zhang, Zhiyu Zhang, Abdel Elkahloun, Donglin Cao, Chen Shen, Mark Wunderlich, Yungui Wang, Mary Beth Neilly, Jie Jin, Minjie Wei, Jun Lu, Peter J.M. Valk, Ruud Delwel, Bob Lowenberg, Michelle M. Le Beau, James Vardiman, James C. Mulloy, Nancy J. Zeleznik-Le, Paul P. Liu, Jiwang Zhang and Jianjun Chen | | | HOX9A and MEIS1 are key oncogenes in MLL-rearranged leukaemia. miRNA-196b is shown here to directly suppress their expression and delay MLL-fusion-mediated leukaemia, but to also cause an aggressive leukaemia phenotype when expressed ectopically, suggesting that it targets tumour suppressors as well. | | | 21 Feb | Nat Commun 3:688 doi:10.1038/ncomms1681 (2012) | | | Biological sciences Cancer | | | Genetics | | | Medical research | | Abstract | Full Text | PDF (2,143 kB) |
Supplementary Information |
| The dynamic stator stalk of rotary ATPases OPEN | | | Alastair G. Stewart, Lawrence K. Lee, Mhairi Donohoe, Jessica J. Chaston and Daniela Stock | | | The peripheral stalks of rotary ATPases counteract torque generated by rotation of the central stalk during ATP synthesis or hydrolysis. Stewart et al. report the crystal structure of an A-type ATPase/synthase peripheral stalk and identify bending and twisting motions that permit the radial wobbling of the headgroup. | | | 21 Feb | Nat Commun 3:687 doi:10.1038/ncomms1693 (2012) | | | Biological sciences Biochemistry | | | Biophysics | | Abstract | Full Text | PDF (1,594 kB) |
Supplementary Information |
| Draft genome sequence and genetic transformation of the oleaginous alga Nannochloropis gaditana OPEN | | | Randor Radakovits, Robert E. Jinkerson, Susan I. Fuerstenberg, Hongseok Tae, Robert E. Settlage, Jeffrey L. Boore and Matthew C. Posewitz | | | Algae show much promise in the production of biofuels owing to their high photoautotrophic biomass and lipid production rates. In this study, the draft genome of Nannochloropsis gaditana CCMP526 and a method for the transformation of this alga are reported, facilitating the investigation of lipid synthesis and biofuel production. | | | 21 Feb | Nat Commun 3:686 doi:10.1038/ncomms1688 (2012) | | | Biological sciences Biotechnology | | | Genetics Plant sciences | | Abstract | Full Text | PDF (1,401 kB) |
Supplementary Information |
| Stress-induced chemical waves in sediment burial diagenesis | | | Yifeng Wang and David A. Budd | | | Dolomite sedimentary rock has lateral metre-scale periodic variations in porosity and composition, which may provide information on formation and transformation. This study suggests that such variations are fossilized chemical waves emerging from stress-mediated mineral-water interaction during sediment burial diagenesis. | | | 21 Feb | Nat Commun 3:685 doi:10.1038/ncomms1684 (2012) | | | Earth sciences Geology and geophysics | | Abstract | Full Text | PDF (594 kB) |
Supplementary Information |
| Resolving the electromagnetic mechanism of surface-enhanced light scattering at single hot spots OPEN | | | P. Alonso-González, P. Albella, M. Schnell, J. Chen, F. Huth, A. García-Etxarri, F. Casanova, F. Golmar, L. Arzubiaga, L.E. Hueso, J. Aizpurua and R. Hillenbrand | | | Light scattering from nanoscale objects can be dramatically enhanced in the proximity of optical antennas. Here, by studying the amplitude and phase of the light scattered from a tip located at the hot spot of an antenna, the underlying electromagnetic mechanism of this enhancement is resolved. | | | 21 Feb | Nat Commun 3:684 doi:10.1038/ncomms1674 (2012) | | | Physical sciences Applied physics | | | Materials science Nanotechnology | | Abstract | Full Text | PDF (958 kB) |
Supplementary Information |
| Sensing of mammalian IL-17A regulates fungal adaptation and virulence | | | Teresa Zelante, Rossana G. Iannitti, Antonella De Luca, Javier Arroyo, Noelia Blanco, Giuseppe Servillo, Dominique Sanglard, Utz Reichard, Glen E. Palmer, Jean-Paul Latgè, Paolo Puccetti and Luigina Romani | | | It is unclear whether pathogens can advantageously exploit the host's immune response. Using Candida albicans, the authors show that host IL-17A binds to the fungi and induces nutrient starvation and autophagy, which eventually leads to enhanced biofilm formation and resistance to the hosts' defence. | | | 21 Feb | Nat Commun 3:683 doi:10.1038/ncomms1685 (2012) | | | Biological sciences Immunology | | | Microbiology | | Abstract | Full Text | PDF (1,777 kB) |
Supplementary Information |
| Stochastic signalling rewires the interaction map of a multiple feedback network during yeast evolution OPEN | | | Chieh Hsu, Simone Scherrer, Antoine Buetti-Dinh, Prasuna Ratna, Julia Pizzolato, Vincent Jaquet and Attila Becskei | | | GAL genes enhance their own transcription via the transcription factor Gal4p, and the number of Galp4 sites in a promoter is expected to strengthen the feedback. In this study, Hsu et al. show that instead the feedback loops are activated by genes that have frequent bursts of expression and fast RNA decay kinetics. | | | 21 Feb | Nat Commun 3:682 doi:10.1038/ncomms1687 (2012) | | | Biological sciences Biotechnology | | | Evolution Microbiology | | Abstract | Full Text | PDF (1,410 kB) |
Supplementary Information |
| Unique domain appended to vertebrate tRNA synthetase is essential for vascular development OPEN | | | Xiaoling Xu, Yi Shi, Hui-Min Zhang, Eric C. Swindell, Alan G. Marshall, Min Guo, Shuji Kishi and Xiang-Lei Yang | | | Seryl-tRNA synthetase is important in vasculogenesis and contains a unique domain at its C-terminus. In this study, the unique domain is shown to target the protein to the nucleus, block expression of vegfa and be essential for vasculogenesis in zebrafish. | | | 21 Feb | Nat Commun 3:681 doi:10.1038/ncomms1686 (2012) | | | Biological sciences Biochemistry | | | Developmental biology Molecular biology | | | | Abstract | Full Text | PDF (1,373 kB) |
Supplementary Information |
| An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid OPEN | | | Marc de la Roche, Trevor J. Rutherford, Deepti Gupta, Dmitry B. Veprintsev, Barbara Saxty, Stefan M. Freund and Mariann Bienz | | | β-Catenin can be oncogenic but finding inhibitors has been a challenge. Here, five compounds are identified, which attenuate transcriptional β-catenin outputs in colorectal cancer cells, and the response to one of them is shown to require an intrinsically labile α-helix next to the BCL9-binding site in β-catenin. | | | 21 Feb | Nat Commun 3:680 doi:10.1038/ncomms1680 (2012) | | | Biological sciences Biophysics | | | Cell biology Chemical biology | | | | Abstract | Full Text | PDF (1,101 kB) |
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