TABLE OF CONTENTS
| | | | Volume 106, Issue 4 (617-792) Published online 14 February 2012
| | In this issue Editorial Minireview Clinical Studies Translational Therapeutics Molecular Diagnostics Genetics and Genomics Corrigenda
Also new today Advance online publication
| | | | | Advertisement | | British Journal of Cancer publishes high quality original papers and reviews that make a significant contribution to increasing understanding of the causes of cancer and to improving the treatment and survival of patients. Visit the journal online at www.bjcancer.com to view the latest research and access selected articles FREE of charge. | | | | Editorial | Top | | Second-line treatment for renal cell cancerG Di Lorenzo, S De Placido and C Buonerba Br J Cancer 2012 106: 617-618; 10.1038/bjc.2011.611 Full Text | | Minireview | Top | | Functional imaging: what evidence is there for its utility in clinical trials of targeted therapies?N Tunariu, S B Kaye and N M deSouza Br J Cancer 2012 106: 619-628; advance online publication, January 26, 2012; 10.1038/bjc.2011.579 Abstract | Full Text | | Clinical Studies | Top | | Open-label feasibility study of pazopanib, carboplatin, and paclitaxel in women with newly diagnosed, untreated, gynaecologic tumours: a phase I/II trial of the AGO study groupA du Bois, I Vergote, P Wimberger, I Ray-Coquard, P Harter, L B Curtis and I Mitrica Br J Cancer 2012 106: 629-632; advance online publication, January 12, 2012; 10.1038/bjc.2011.608 Abstract | Full Text | | | | CA-125 can be part of the tumour evaluation criteria in ovarian cancer trials: experience of the GCIG CALYPSO trialJ Alexandre, C Brown, D Coeffic, N Raban, J Pfisterer, J Mäenpää, H Chalchal, B Fitzharris, B Volgger, I Vergote, C Pisano, A Ferrero and E Pujade-Lauraine Br J Cancer 2012 106: 633-637; advance online publication, January 12, 2012; 10.1038/bjc.2011.593 Abstract | Full Text | | | | Survival gains needed to offset persistent adverse treatment effects in localised prostate cancerM T King, R Viney, D P Smith, I Hossain, D Street, E Savage, S Fowler, M P Berry, M Stockler, P Cozzi, P Stricker, J Ward and B K Armstrong Br J Cancer 2012 106: 638-645; advance online publication, January 24, 2012; 10.1038/bjc.2011.552 Abstract | Full Text | | | | Baseline quality of life as a prognostic survival tool in patients receiving sunitinib for metastatic renal cell carcinomaD Cella, A G Bushmakin, J C Cappelleri, C Charbonneau, M D Michaelson and R J Motzer Br J Cancer 2012 106: 646-650; advance online publication, January 12, 2012; 10.1038/bjc.2011.589 Abstract | Full Text | | | | Internet chemotherapy information: impact on patients and health professionalsE Davies and K-W Yeoh Br J Cancer 2012 106: 651-657; advance online publication, January 19, 2012; 10.1038/bjc.2011.601 Abstract | Full Text | | | | Triplets versus doublets, with or without cisplatin, in the first-line treatment of stage IIIB–IV non-small cell lung cancer (NSCLC) patients: a multicenter randomised factorial trial (FAST)C Boni, M Tiseo, L Boni, E Baldini, F Recchia, C Barone, F Grossi, D Germano, E Matano, G Marini, R Labianca, F Di Costanzo, A Bagnulo, C Pennucci, C Caroti, M Mencoboni, F Zanelli, T Prochilo, M A Cafferata and A Ardizzoni on behalf of Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC) Investigators Br J Cancer 2012 106: 658-665; advance online publication, January 12, 2012; 10.1038/bjc.2011.606 Abstract | Full Text | | | | Phase I first-in-human study of TAK-285, a novel investigational dual HER2/EGFR inhibitor, in cancer patientsT Doi, H Takiuchi, A Ohtsu, N Fuse, M Goto, M Yoshida, N Dote, Y Kuze, F Jinno, M Fujimoto, T Takubo, N Nakayama and R Tsutsumi Br J Cancer 2012 106: 666-672; advance online publication, January 12, 2012; 10.1038/bjc.2011.590 Abstract | Full Text | | | | Phase I study of lapatinib plus vinorelbine in patients with locally advanced or metastatic breast cancer overexpressing HER2E Brain, N Isambert, F Dalenc, V Diéras, J Bonneterre, K Rezai, M Jimenez, F Mefti-Lacheraf, E Cottura, P Tresca, L Vanlemmens, C Mahier-Aït Oukhatar, F Lokiec and P Fumoleau Br J Cancer 2012 106: 673-677; advance online publication, January 12, 2012; 10.1038/bjc.2011.591 Abstract | Full Text | | | | A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumoursU Lassen, D L Nielsen, M Sørensen, L Winstedt, T Niskanen, Y Stenberg, S Pakola, J-M Stassen and S Glazer Br J Cancer 2012 106: 678-684; advance online publication, January 24, 2012; 10.1038/bjc.2011.609 Abstract | Full Text | | Translational Therapeutics | Top | | The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosisJ Follet, L Corcos, G Baffet, F Ezan, F Morel, B Simon and C Le Jossic-Corcos Br J Cancer 2012 106: 685-692; advance online publication, January 31, 2012; 10.1038/bjc.2012.6 Abstract | Full Text | | | | Sigma-2 ligands induce tumour cell death by multiple signalling pathwaysC Zeng, J Rothfuss, J Zhang, W Chu, S Vangveravong, Z Tu, F Pan, K C Chang, R Hotchkiss and R H Mach Br J Cancer 2012 106: 693-701; advance online publication, January 17, 2012; 10.1038/bjc.2011.602 Abstract | Full Text | | Molecular Diagnostics | Top | | The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinomaS Dutta, J J Going, A B C Crumley, Z Mohammed, C Orange, J Edwards, G M Fullarton, P G Horgan and D C McMillan Br J Cancer 2012 106: 702-710; advance online publication, January 12, 2012; 10.1038/bjc.2011.610 Abstract | Full Text | | | | The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cellsM J Nyhan, T R O'Donovan, B Elzinga, L C Crowley, G C O'Sullivan and S L McKenna Br J Cancer 2012 106: 711-718; advance online publication, January 12, 2012; 10.1038/bjc.2011.604 Abstract | Full Text | | | | Loss of PTEN is associated with elevated EGFR and HER2 expression and worse prognosis in salivary gland cancerT Ettl, K Baader, C Stiegler, M Müller, A Agaimy, J Zenk, T Kühnel, M Gosau, K Zeitler, S Schwarz and G Brockhoff Br J Cancer 2012 106: 719-726; advance online publication, January 12, 2012; 10.1038/bjc.2011.605 Abstract | Full Text | | | | FGFR2 gene amplification and clinicopathological features in gastric cancerK Matsumoto, T Arao, T Hamaguchi, Y Shimada, K Kato, I Oda, H Taniguchi, F Koizumi, K Yanagihara, H Sasaki, K Nishio and Y Yamada Br J Cancer 2012 106: 727-732; advance online publication, January 12, 2012; 10.1038/bjc.2011.603 Abstract | Full Text | | | | Serum biomarker panels for the diagnosis of gastric adenocarcinomaH S Ahn, Y S Shin, P J Park, K N Kang, Y Kim, H-J Lee, H-K Yang and C W Kim Br J Cancer 2012 106: 733-739; advance online publication, January 12, 2012; 10.1038/bjc.2011.592 Abstract | Full Text | | | | Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasmaH Konishi, D Ichikawa, S Komatsu, A Shiozaki, M Tsujiura, H Takeshita, R Morimura, H Nagata, T Arita, T Kawaguchi, S Hirashima, H Fujiwara, K Okamoto and E Otsuji Br J Cancer 2012 106: 740-747; advance online publication, January 19, 2012; 10.1038/bjc.2011.588 Abstract | Full Text | | | | Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancerE Dotan, N J Meropol, F Zhu, F Zambito, B Bove, K Q Cai, A K Godwin, E A Golemis, I Astsaturov and S J Cohen Br J Cancer 2012 106: 748-755; advance online publication, January 12, 2012; 10.1038/bjc.2011.587 Abstract | Full Text | | | | Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patientsM P Myklebust, Ø Fluge, H Immervoll, A Skarstein, L Balteskard, O Bruland and O Dahl Br J Cancer 2012 106: 756-762; 10.1038/bjc.2011.548 Abstract | Full Text | | | | Combined effect of ALK and MEK inhibitors in EML4–ALK-positive non-small-cell lung cancer cellsJ Tanizaki, I Okamoto, K Takezawa, K Sakai, K Azuma, K Kuwata, H Yamaguchi, E Hatashita, K Nishio, P A Janne and K Nakagawa Br J Cancer 2012 106: 763-767; advance online publication, January 12, 2012; 10.1038/bjc.2011.586 Abstract | Full Text | | | | Changes in circulating microRNA levels associated with prostate cancerR J Bryant, T Pawlowski, J W F Catto, G Marsden, R L Vessella, B Rhees, C Kuslich, T Visakorpi and F C Hamdy Br J Cancer 2012 106: 768-774; advance online publication, January 12, 2012; 10.1038/bjc.2011.595 Abstract | Full Text | | Genetics and Genomics | Top | | Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older womenL Sidon, S Ingham, T Clancy, R Clayton, A Clarke, E A Jones, F Lalloo and D G R Evans Br J Cancer 2012 106: 775-779; advance online publication, December 20, 2011; 10.1038/bjc.2011.573 Abstract | Full Text | | | | Role of micronucleus test in predicting breast cancer susceptibility: a systematic review and meta-analysisF Cardinale, P Bruzzi and C Bolognesi Br J Cancer 2012 106: 780-790; advance online publication, December 20, 2011; 10.1038/bjc.2011.567 Abstract | Full Text | | Corrigenda | Top | | Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumoursM A Rijlaarsdam, H A D M van Herk, A J M Gillis, H Stoop, G Jenster, J Martens, G J L H van Leenders, W Dinjens, A M Hoogland, M Timmermans and L H J Looijenga Br J Cancer 2012 106: 791; 10.1038/bjc.2012.37 Full Text | | | | Specific activity of cyclin-dependent kinase I is a new potential predictor of tumour recurrence in stage II colon cancerE C M Zeestraten, M Maak, M Shibayama, T Schuster, U Nitsche, T Matsushima, S Nakayama, K Gohda, H Friess, C J H van de Velde, H Ishihara, R Rosenberg, P J K Kuppen and K-P Janssen Br J Cancer 2012 106: 792; 10.1038/bjc.2012.38 Full Text | | | | | | Advertisement | | Ensure your access to British Journal of Cancer If you are unable to access the articles in this Table of Contents e-alert, your library may not subscribe to this journal. 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