Leukemia - Table of Contents alert Volume 25 Issue 10

TABLE OF CONTENTS Volume 25, Issue 10 (October 2011) In this issue Spotlight Review Review Original Articles Letters to the Editor Also new AOP Advertisment Innovative solutions for blood cell disorders Delivering the building blocks for patient care, BD Biosciences provides innovative flow cytometry reagents and instrumentation used in the identification of various markers associated with blood cell disorders. Learn more about our solutions that enable high clinical performance and reliable results for neoplastic blood cell disorder patient care. Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Take a Closer Look at Myeloproliferative Neoplams  Discover a reliable source of information and physician resources related to myeloproliferative neoplasms (MPNs). Find valuable information about the role of JAK Pathway in Myeloproliferative Neoplams. Exploring MPN G-INC-1030929     Spotlight Review Top Notch signaling in mammalian hematopoietic stem cells K V Pajcini, N A Speck and W S Pear Leukemia 2011 25: 1525-1532; advance online publication, June 7, 2011; 10.1038/leu.2011.127 Abstract | Full Text Review Top The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma S K Martin, P Diamond, S Gronthos, D J Peet and A C W Zannettino Leukemia 2011 25: 1533-1542; advance online publication, June 3, 2011; 10.1038/leu.2011.122 Abstract | Full Text Original Articles Top THERAPY A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia M H Kirschbaum, T Synold, A S Stein, J Tuscano, J M Zain, L Popplewell, C Karanes, M R O'Donnell, B Pulone, A Rincon, J Wright, P Frankel, S J Forman and E M Newman Leukemia 2011 25: 1543-1547; advance online publication, May 31, 2011; 10.1038/leu.2011.124 Abstract | Full Text ACUTE LEUKEMIAS Predictive impact of allele-matching and EBMT risk score for outcome after T-cell depleted unrelated donor transplantation in poor-risk acute leukemia and myelodysplasia T Lodewyck, M Oudshoorn, B van der Holt, E Petersen, E Spierings, P A von dem Borne, A Schattenberg, W Allebes, M Groenendijk-Sijnke, L Duinhouwer, R Willemze, B Lowenberg, L F Verdonck, E Meijer and J J Cornelissen Leukemia 2011 25: 1548-1554; advance online publication, May 24, 2011; 10.1038/leu.2011.123 Abstract | Full Text Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles M G Loudin, J Wang, H-C Eastwood Leung, S Gurusiddappa, J Meyer, G Condos, D Morrison, A Tsimelzon, M Devidas, N A Heerema, A J Carroll, S E Plon, S P Hunger, G Basso, A Pession, D Bhojwani, W L Carroll and K R Rabin Leukemia 2011 25: 1555-1563; advance online publication, June 7, 2011; 10.1038/leu.2011.128 Abstract | Full Text Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL M L Sulis, P Saftig and A A Ferrando Leukemia 2011 25: 1564-1569; advance online publication, May 31, 2011; 10.1038/leu.2011.130 Abstract | Full Text IDH1 and IDH2 mutations in pediatric acute leukemia A K Andersson, D W Miller, J A Lynch, A S Lemoff, Z Cai, S B Pounds, I Radtke, B Yan, J D Schuetz, J E Rubnitz, R C Ribeiro, S C Raimondi, J Zhang, C G Mullighan, S A Shurtleff, B A Schulman and J R Downing Leukemia 2011 25: 1570-1577; advance online publication, June 7, 2011; 10.1038/leu.2011.133 Abstract | Full Text TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells B A Cardoso, S F de Almeida, A B A Laranjeira, M Carmo-Fonseca, J A Yunes, P J Coffer and J T Barata Leukemia 2011 25: 1578-1586; advance online publication, June 7, 2011; 10.1038/leu.2011.140 Abstract | Full Text IMMUNOLOGY Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation A Kreutzman, K Ladell, C Koechel, E Gostick, M Ekblom, L Stenke, T Melo, H Einsele, K Porkka, D A Price, S Mustjoki and R Seggewiss Leukemia 2011 25: 1587-1597; advance online publication, June 7, 2011; 10.1038/leu.2011.135 Abstract | Full Text LYMPHOMA Cooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma Z Qin, L Dai, M Bratoeva, M G Slomiany, B P Toole and C Parsons Leukemia 2011 25: 1598-1609; advance online publication, June 10, 2011; 10.1038/leu.2011.144 Abstract | Full Text MYELOMA Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T lymphocytes: a potential therapeutic application in multiple myeloma J Bae, R Carrasco, A-H Lee, R Prabhala, Y-T Tai, K C Anderson and N C Munshi Leukemia 2011 25: 1610-1619; advance online publication, June 10, 2011; 10.1038/leu.2011.120 Abstract | Full Text Impact of lenalidomide dose on progression-free survival in patients with relapsed or refractory multiple myeloma M A Dimopoulos, M Hussein, A S Swern and D Weber Leukemia 2011 25: 1620-1626; advance online publication, July 12, 2011; 10.1038/leu.2011.126 Abstract | Full Text Stem cell mobilization in patients with newly diagnosed multiple myeloma after lenalidomide induction therapy F Cavallo, S Bringhen, G Milone, D Ben-Yehuda, A Nagler, E Calabrese, N Cascavilla, V Montefusco, B Lupo, A M Liberati, C Crippa, F Rossini, R Passera, F Patriarca, A M Cafro, P Omedè, A M Carella, J Peccatori, L Catalano, T Caravita, P Musto, M T Petrucci, M Boccadoro and A Palumbo Leukemia 2011 25: 1627-1631; advance online publication, June 3, 2011; 10.1038/leu.2011.131 Abstract | Full Text Letters to the Editor Top Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2 by juxtaposition with MBNL1 and STAG2 S Chen, S Nagel, B Schneider, M Kaufmann, C Meyer, M Zaborski, U R Kees, H G Drexler and R A F MacLeod Leukemia 2011 25: 1632-1635; advance online publication, June 7, 2011; 10.1038/leu.2011.119 Full Text Stable and reproducible engraftment of primary adult and pediatric acute myeloid leukemia in NSG mice M Malaisé, M Neumeier, C Botteron, K Döhner, D Reinhardt, B Schlegelberger, G Göhring, B Gruhn, K-M Debatin and S Corbacioglu Leukemia 2011 25: 1635-1639; advance online publication, June 7, 2011; 10.1038/leu.2011.121 Full Text An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia T Herold, V Jurinovic, K H Metzeler, A-L Boulesteix, M Bergmann, T Seiler, M Mulaw, S Thoene, A Dufour, Z Pasalic, M Schmidberger, M Schmidt, S Schneider, P M Kakadia, M Feuring-Buske, J Braess, K Spiekermann, U Mansmann, W Hiddemann, C Buske and S K Bohlander Leukemia 2011 25: 1639-1645; advance online publication, May 31, 2011; 10.1038/leu.2011.125 Full Text A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL) P M Kakadia, B Tizazu, G Mellert, J Harbott, S Röttgers, H Quentmeier, K Spiekermann and S K Bohlander Leukemia 2011 25: 1645-1649; advance online publication, May 31, 2011; 10.1038/leu.2011.129 Full Text Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia N Konstandin, S Bultmann, A Szwagierczak, A Dufour, B Ksienzyk, F Schneider, T Herold, M Mulaw, P M Kakadia, S Schneider, K Spiekermann, H Leonhardt and S K Bohlander Leukemia 2011 25: 1649-1652; advance online publication, May 31, 2011; 10.1038/leu.2011.134 Full Text Immunophenotype-defined sub-populations are common at diagnosis in childhood B-cell precursor acute lymphoblastic leukemia N F Øbro, H V Marquart, H O Madsen, L P Ryder, M K Andersen, B Lausen, B K Albertsen, P S Wehner, J Helgestad and K Schmiegelow Leukemia 2011 25: 1652-1657; advance online publication, June 17, 2011; 10.1038/leu.2011.136 Full Text Donor KIR haplotype B improves progression-free and overall survival after allogeneic hematopoietic stem cell transplantation for multiple myeloma N Kröger, T Zabelina, J Berger, H Duske, E Klyuchnikov, T Binder, T Stübig, Y Hilde-brandt, D Atanackovic, H Alchalby, F Ayuk, A R Zander, U Bacher and T Eiermann Leukemia 2011 25: 1657-1661; advance online publication, June 7, 2011; 10.1038/leu.2011.138 Full Text Mutation analysis of TET2, IDH1, IDH2 and ASXL1 in chronic myeloid leukemia C Roche-Lestienne, A Marceau, E Labis, O Nibourel, V Coiteux, J Guilhot, L Legros, F Nicolini, P Rousselot, M Gardembas, N Helevaut, C Frimat, F-X Mahon, F Guilhot and C Preudhomme on the behalf of the Fi-LMC group Leukemia 2011 25: 1661-1664; advance online publication, June 3, 2011; 10.1038/leu.2011.139 Full Text Advertisement Nature Reviews Cancer Turns 10 Nature Reviews Cancer celebrates its 10 year anniversary with a specially commissioned Article Series that explores today's hottest research areas such as epigenetics, heterogeneity and metastasis, as well as forward looking concepts that could result in new treatments for cancer patients. 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