TABLE OF CONTENTS
| | | | Volume 24, Issue 5 (May 2016) | | In this issue Editorial In This Issue Research Highlights Commentaries Original Articles
Also new AOP | | | | Editorial | Top | | Overcoming Challenges in CAR T-cell Product CGMP ReleaseConcetta Quintarelli, Franco Locatelli, Ignazio Caruana and Biagio De Angelis Mol Ther 2016 24: 845-846; 10.1038/mt.2016.72 Full Text | | In This Issue | Top | | In This IssueMol Ther 2016 24: 847; 10.1038/mt.2016.73 Full Text | | Research Highlights | Top | | Research HighlightsMol Ther 2016 24: 848; 10.1038/mt.2016.74 Full Text | | Commentaries | Top | | Multistage Delivery Technologies: Multifunctional, Interdisciplinary Approaches to NanomedicineMatthew T Haynes and Leaf Huang Mol Ther 2016 24: 849-851; 10.1038/mt.2016.75 Full Text | | | | Endogenous Transposase Source in Human Cells Mobilizes piggyBac TransposonsZoltán Ivics Mol Ther 2016 24: 851-854; 10.1038/mt.2016.76 Full Text | | Original Articles | Top | | Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose DependentMonir Shababi, Zhihua Feng, Eric Villalon, Christine M Sibigtroth, Erkan Y Osman, Madeline R Miller, Patricka A Williams-Simon, Abby Lombardi, Thalia H Sass, Arleigh K Atkinson, Michael L Garcia, Chien-Ping Ko and Christian L Lorson Mol Ther 2016 24: 855-866; advance online publication, February 10, 2016; 10.1038/mt.2016.33 Abstract | Full Text | | | | AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient DogsVirginie Pichard, Nathalie Provost, Alexandra Mendes-Madeira, Lyse Libeau, Philippe Hulin, Kizito-Tshitoko Tshilenge, Marine Biget, Baptiste Ameline, Jack-Yves Deschamps, Michel Weber, Guylène Le Meur, Marie-Anne Colle, Philippe Moullier and Fabienne Rolling Mol Ther 2016 24: 867-876; advance online publication, February 9, 2016; 10.1038/mt.2016.37 Abstract | Full Text | | | | Gene Transfer of Brain-derived Neurotrophic Factor (BDNF) Prevents Neurodegeneration Triggered by FXN DeficiencyYurika Katsu-Jiménez, Frida Loría, Juan Carlos Corona and Javier Díaz-Nido Mol Ther 2016 24: 877-889; advance online publication, February 5, 2016; 10.1038/mt.2016.32 Abstract | Full Text | | | | Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8Delphine Demeestere, Eline Dejonckheere, Sophie Steeland, Paco Hulpiau, Jurgen Haustraete, Nick Devoogdt, Rielana Wichert, Christoph Becker-Pauly, Elien Van Wonterghem, Sylviane Dewaele, Griet Van Imschoot, Jeroen Aerts, Lutgarde Arckens, Yvan Saeys, Claude Libert and Roosmarijn E Vandenbroucke Mol Ther 2016 24: 890-902; advance online publication, January 18, 2016; 10.1038/mt.2016.2 Abstract | Full Text | | | | SSRP1 Contributes to the Malignancy of Hepatocellular Carcinoma and Is Negatively Regulated by miR-497MTOPENQianshan Ding, Ke He, Tao Luo, Yunchao Deng, Hanning Wang, Hao Liu, Jinqian Zhang, Kaiyun Chen, Jinfeng Xiao, Xiaopeng Duan, Rui Huang, Zhenglin Xia, Wenjie Zhou, Jinliang He, Honggang Yu, Xingyuan Jiao and Guoan Xiang Mol Ther 2016 24: 903-914; advance online publication, January 12, 2016; 10.1038/mt.2016.9 Abstract | Full Text | | | | Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage ProductionYingying Yao, Yi Wang, Zhijun Zhang, Long He, Jianghui Zhu, Meng Zhang, Xiaoyu He, Zhenshun Cheng, Qilin Ao, Yong Cao, Ping Yang, Yunchao Su, Jianping Zhao, Shu Zhang, Qilin Yu, Qin Ning, Xudong Xiang, Weining Xiong, Cong-Yi Wang and Yongjian Xu Mol Ther 2016 24: 915-925; advance online publication, February 17, 2016; 10.1038/mt.2016.36 Abstract | Full Text | | | | Inhibiting Notch Activity in Breast Cancer Stem Cells by Glucose Functionalized Nanoparticles Carrying γ-secretase InhibitorsMTOPENVeronika Mamaeva, Rasmus Niemi, Michaela Beck, Ezgi Özliseli, Diti Desai, Sebastian Landor, Tove Gronroos, Pauliina Kronqvist, Ina K N Pettersen, Emmet McCormack, Jessica M Rosenholm, Mika Linden and Cecilia Sahlgren Mol Ther 2016 24: 926-936; advance online publication, February 26, 2016; 10.1038/mt.2016.42 Abstract | Full Text | | | | MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular AtrophyMTOPENNaemeh Pourshafie, Philip R Lee, Ke-lian Chen, George G Harmison, Laura C Bott, Masahisa Katsuno, Gen Sobue, Barrington G Burnett, Kenneth H Fischbeck and Carlo Rinaldi Mol Ther 2016 24: 937-945; advance online publication, January 12, 2016; 10.1038/mt.2016.13 Abstract | Full Text | | | | Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA MimicsMTOPENMasayuki Matsui, Thazha P Prakash and David R Corey Mol Ther 2016 24: 946-955; advance online publication, February 23, 2016; 10.1038/mt.2016.39 Abstract | Full Text | | | | Induced Apoptosis Investigation in Wild-type and FLT3-ITD Acute Myeloid Leukemia Cells by Nanochannel Electroporation and Single-cell qRT-PCRKeliang Gao, Xiaomeng Huang, Chi-Ling Chiang, Xinmei Wang, Lingqian Chang, Pouyan Boukany, Guido Marcucci, Robert Lee and Ly James Lee Mol Ther 2016 24: 956-964; advance online publication, January 19, 2016; 10.1038/mt.2016.6 Abstract | Full Text | | | | Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington’s Disease Mouse ModelsMTOPENKari Pollock, Heather Dahlenburg, Haley Nelson, Kyle D Fink, Whitney Cary, Kyle Hendrix, Geralyn Annett, Audrey Torrest, Peter Deng, Joshua Gutierrez, Catherine Nacey, Karen Pepper, Stefanos Kalomoiris, Johnathon D Anderson, Jeannine McGee, William Gruenloh, Brian Fury, Gerhard Bauer, Alexandria Duffy, Theresa Tempkin, Vicki Wheelock and Jan A Nolta Mol Ther 2016 24: 965-977; advance online publication, January 14, 2016; 10.1038/mt.2016.12 Abstract | Full Text | | | | A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial CellsMTOPENMounia Boulberdaa, Elizabeth Scott, Margaret Ballantyne, Raquel Garcia, Betty Descamps, Gianni D Angelini, Mairi Brittan, Amanda Hunter, Martin McBride, John McClure, Joseph M Miano, Costanza Emanueli, Nicholas L Mills, Joanne C Mountford and Andrew H Baker Mol Ther 2016 24: 978-990; advance online publication, February 22, 2016; 10.1038/mt.2016.41 Abstract | Full Text | | | | H7N9 Live Attenuated Influenza Vaccine Is Highly Immunogenic, Prevents Virus Replication, and Protects Against Severe Bronchopneumonia in FerretsJørgen de Jonge, Irina Isakova-Sivak, Harry van Dijken, Sanne Spijkers, Justin Mouthaan, Rineke de Jong, Tatiana Smolonogina, Paul Roholl and Larisa Rudenko Mol Ther 2016 24: 991-1002; advance online publication, January 22, 2016; 10.1038/mt.2016.23 Abstract | Full Text | | | | Development of an Interleukin-1β Vaccine in Patients with Type 2 DiabetesClaudia Cavelti-Weder, Katharina Timper, Eleonora Seelig, Cornelia Keller, Martin Osranek, Ute Lässing, Gunther Spohn, Patrik Maurer, Philipp Müller, Gary T Jennings, Joerg Willers, Philippe Saudan, Marc Y Donath and Martin F Bachmann Mol Ther 2016 24: 1003-1012; advance online publication, December 21, 2015; 10.1038/mt.2015.227 Abstract | Full Text | | | | | Advertisement | | Open for Submissions
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